8,771 research outputs found
Land landing couch dynamics computer program
Computer programs perform landing stability studies of mechanical impact system designs for advanced spacecraft. The programs consider variation in spacecraft vertical and horizontal velocity, attitude and orientation, shock strut load-stroke characteristics, and ground coefficient of friction
The relation between solar cell flight performance data and materials and manufacturing data Final report
Flight performance data for solar cell power systems in satellites and correlation with manufacturing methods and material
Jupiter: Its infrared spectrum from 10 to 40 microns
Spectral measurements of the thermal radiation from Jupiter in the 16-40 micrometer band were analyzed under the assumption that pressure broadened H2 transitions are responsible for the bulk of the infrared opacity over most of this spectral interval. Both the vertical pressure-temperature profile and the hydrogen mixing ratio were determined. The derived value of the molecular hydrogen mixing ratio, 0.89 + or - 0.11, is consistent with the solar value, 0.86
HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in bunionectomy: phase III results from the randomized EPOCH 1 study.
BACKGROUND AND OBJECTIVES: There is a need for local anesthetics that provide consistent analgesia through 72 hours after surgery. This study evaluates the use of HTX-011 (bupivacaine and meloxicam in Biochronomerpolymer technology), an extended-release, dual-acting local anesthetic, in reducing both postoperative pain over 72 hours and postoperative opioid use when compared with bupivacaine hydrochloride (HCl) and saline placebo. Inclusion of low-dose meloxicam in HTX-011 is designed to reduce local inflammation caused by surgery, potentiating the analgesic effect of bupivacaine. Previously, significant synergy has been observed with bupivacaine and meloxicam with both given locally together.
METHODS: EPOCH 1 was a randomized, double-blind, placebo-controlled and active-controlled phase III study in subjects undergoing a primary unilateral, distal, first metatarsal bunionectomy in which subjects received either a single intraoperative dose of HTX-011, immediate-release bupivacaine HCl or saline placebo.
RESULTS: A total of 412 subjects were dosed. The results for the primary and all four key secondary endpoints were statistically significant in favor of HTX-011. HTX-011 demonstrated superior, sustained pain reduction through 72 hours, significantly reduced opioid consumption and resulted in significantly more opioid-free subjects compared with saline placebo and bupivacaine HCl. Safety was similar across groups with fewer opioid-related adverse events observed in the HTX-011 group.
CONCLUSIONS: HTX-011 demonstrated significant reduction in postoperative pain through 72 hours with significant reduction in opioid consumption and a significant increase in the proportion of opioid-free subjects compared with saline placebo and the most widely used local anesthetic, bupivacaine HCl.
TRIAL REGISTRATION NUMBER: NCT03295721
A Demonstration of LISA Laser Communication
Over the past few years questions have been raised concerning the use of
laser communications links between sciencecraft to transmit phase information
crucial to the reduction of laser frequency noise in the LISA science
measurement. The concern is that applying medium frequency phase modulations to
the laser carrier could compromise the phase stability of the LISA fringe
signal. We have modified the table-top interferometer presented in a previous
article by applying phase modulations to the laser beams in order to evaluate
the effects of such modulations on the LISA science fringe signal. We have
demonstrated that the phase resolution of the science signal is not degraded by
the presence of medium frequency phase modulations.Comment: minor corrections found in the CQG versio
The Hidden Disability Consensus in the 2020 Campaign
At this writing, the final results of the Iowa caucuses remain unreported. No one yet knows which candidates did well and which did poorly. We do know that health policy is a defining cleavage between left and liberal Democrats this primary season. Much of the press coverage will naturally focus on the implications of this vote for Democrats’ commitment to an incremental public option or a full-throated single-payer plan
ALSEP/SIDE/CCGE /Apollo Lunar Surface Experiments Package/Suprathermal Ion Detector Experiment/Cold Cathode Gauge Experiment/. Volume 2 - Appendix Final engineering report
Data for experiments for detecting lunar atmosphere and surface ion emissio
Extreme tunability of interactions in a Li Bose-Einstein condensate
We use a Feshbach resonance to tune the scattering length a of a
Bose-Einstein condensate of 7Li in the |F = 1, m_F = 1> state. Using the
spatial extent of the trapped condensate we extract a over a range spanning 7
decades from small attractive interactions to extremely strong repulsive
interactions. The shallow zero-crossing in the wing of the Feshbach resonance
enables the determination of a as small as 0.01 Bohr radii. In this regime,
evidence of the weak anisotropic magnetic dipole interaction is obtained by
comparison with different trap geometries
Charge Management for Gravitational Wave Observatories using UV LEDs
Accumulation of electrical charge on the end mirrors of gravitational wave
observatories, such as the space-based LISA mission and ground-based LIGO
detectors, can become a source of noise limiting the sensitivity of such
detectors through electronic couplings to nearby surfaces. Torsion balances
provide an ideal means for testing gravitational wave technologies due to their
high sensitivity to small forces. Our torsion pendulum apparatus consists of a
movable Au-coated Cu plate brought near a Au-coated Si plate pendulum suspended
from a non-conducting quartz fiber. A UV LED located near the pendulum
photoejects electrons from the surface, and a UV LED driven electron gun
directs photoelectrons towards the pendulum surface. We have demonstrated both
charging and discharging of the pendulum with equivalent charging rates of
, as well as spectral measurements of the pendulum
charge resulting in a white noise level equivalent to .Comment: 5 pages, submitted to PR
VLBI Polarimetry of 177 Sources from the Caltech-Jodrell Bank Flat-spectrum Survey
We present VLBA observations and a statistical analysis of 5 GHz VLBI
polarimetry data from 177 sources in the Caltech-Jodrell Bank flat-spectrum
(CJF) survey. The CJF survey, a complete, flux-density-limited sample of 293
extragalactic radio sources, gives us the unique opportunity to compare a broad
range of source properties for quasars, galaxies and BL Lacertae objects. We
focus primarily on jet properties, specifically the correlation between the jet
axis angle and the polarization angle in the core and jet. A strong correlation
is found for the electric vector polarization angle in the cores of quasars to
be perpendicular to the jet axis. Contrary to previous claims, no correlation
is found between the jet polarization angle and the jet axis in either quasars
or BL Lac objects. With this large, homogeneous sample we are also able to
investigate cosmological issues and AGN evolution.Comment: Accepted to the Astrophysical Journal: 37 pages, 14 figure
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