7,948 research outputs found

    No-signaling, entanglement-breaking, and localizability in bipartite channels

    Full text link
    A bipartite quantum channel represents the interaction between systems, generally allowing for exchange of information. A special class of bipartite channels are the no-signaling ones, which do not allow communication. In Ref. [1] it has been conjectured that all no-signaling channels are mixtures of entanglement-breaking and localizable channels, which require only local operations and entanglement. Here we provide the general realization scheme, giving a counterexample to the conjecture.Comment: 4 pages, revtex

    Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK.

    Get PDF
    Short-patch repair of DNA single-strand breaks and gaps (SSB) is coordinated by XRCC1, a scaffold protein that recruits the DNA polymerase and DNA ligase required for filling and sealing the damaged strand. XRCC1 can also recruit end-processing enzymes, such as PNK (polynucleotide kinase 3'-phosphatase), Aprataxin and APLF (aprataxin/PNK-like factor), which ensure the availability of a free 3'-hydroxyl on one side of the gap, and a 5'-phosphate group on the other, for the polymerase and ligase reactions respectively. PNK binds to a phosphorylated segment of XRCC1 (between its two C-terminal BRCT domains) via its Forkhead-associated (FHA) domain. We show here, contrary to previous studies, that the FHA domain of PNK binds specifically, and with high affinity to a multiply phosphorylated motif in XRCC1 containing a pSer-pThr dipeptide, and forms a 2:1 PNK:XRCC1 complex. The high-resolution crystal structure of a PNK-FHA-XRCC1 phosphopeptide complex reveals the basis for this unusual bis-phosphopeptide recognition, which is probably a common feature of the known XRCC1-associating end-processing enzymes

    Architectural Education for Today’s Challenges

    Get PDF
    The changing environment in which architecture is practiced today appears very hostile in many countries including Nigeria. There are challenges both within the profession and outside the profession. Several of these challenges have serious implications for the training of architects in the country. This paper highlights some of these challenges and their implications for architectural education in Nigeria. It proffers solutions aimed at making architectural education more responsive to the evolving practice climate in Nigeria

    The Higgs Mass beyond the CMSSM

    Full text link
    The apparent discovery of a Higgs boson with mass ~125 GeV has had a significant impact on the constrained minimal supersymmetric extension of the Standard Model in which the scalar masses, gaugino masses and tri-linear A-terms are assumed to be universal at the GUT scale (the CMSSM). Much of the low-mass parameter space in the CMSSM has been excluded by supersymmetric particle searches at the LHC as well as by the Higgs mass measurement and the emergent signal for B_s to mu^+ mu^-. Here, we consider the impact of these recent LHC results on several variants of the CMSSM with a primary focus on obtaining a Higgs mass of ~125 GeV. In particular, we consider the one- and two-parameter extensions of the CMSSM with one or both of the Higgs masses set independently of the common sfermion mass, m_0 (the NUHM1,2). We also consider the one-parameter extension of the CMSSM in which the input universality scale M_in is below the GUT scale (the sub-GUT CMSSM). We find that when M_in < M_GUT large regions of parameter space open up where the relic density of neutralinos can successfully account for dark matter with a Higgs boson mass ~125 GeV. In some of these regions essential roles are played by coannihilation processes that are usually less important in the CMSSM with M_in = M_GUT. Finally, we reconsider mSUGRA models with sub-GUT universality, which have the same number of parameters as the CMSSM. Here too, we find phenomenologically viable regions of parameter space, which are essentially non-existent in GUT-scale mSUGRA models. Interestingly, we find that the preferred range of the A-term straddles that predicted by the simplest Polonyi model.Comment: 28 pages, 12 figure

    RankPL: A Qualitative Probabilistic Programming Language

    Full text link
    In this paper we introduce RankPL, a modeling language that can be thought of as a qualitative variant of a probabilistic programming language with a semantics based on Spohn's ranking theory. Broadly speaking, RankPL can be used to represent and reason about processes that exhibit uncertainty expressible by distinguishing "normal" from" surprising" events. RankPL allows (iterated) revision of rankings over alternative program states and supports various types of reasoning, including abduction and causal inference. We present the language, its denotational semantics, and a number of practical examples. We also discuss an implementation of RankPL that is available for download

    Structural change of vortex patterns in anisotropic Bose-Einstein condensates

    Get PDF
    We study the changes in the spatial distribution of vortices in a rotating Bose-Einstein condensate due to an increasing anisotropy of the trapping potential. Once the rotational symmetry is broken, we find that the vortex system undergoes a rich variety of structural changes, including the formation of zig-zag and linear configurations. These spatial re-arrangements are well signaled by the change in the behavior of the vortex-pattern eigenmodes against the anisotropy parameter. The existence of such structural changes opens up possibilities for the coherent exploitation of effective many-body systems based on vortex patterns.Comment: 5 pages, 4 figure
    corecore