7,948 research outputs found
No-signaling, entanglement-breaking, and localizability in bipartite channels
A bipartite quantum channel represents the interaction between systems,
generally allowing for exchange of information. A special class of bipartite
channels are the no-signaling ones, which do not allow communication. In Ref.
[1] it has been conjectured that all no-signaling channels are mixtures of
entanglement-breaking and localizable channels, which require only local
operations and entanglement. Here we provide the general realization scheme,
giving a counterexample to the conjecture.Comment: 4 pages, revtex
Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK.
Short-patch repair of DNA single-strand breaks and gaps (SSB) is coordinated by XRCC1, a scaffold protein that recruits the DNA polymerase and DNA ligase required for filling and sealing the damaged strand. XRCC1 can also recruit end-processing enzymes, such as PNK (polynucleotide kinase 3'-phosphatase), Aprataxin and APLF (aprataxin/PNK-like factor), which ensure the availability of a free 3'-hydroxyl on one side of the gap, and a 5'-phosphate group on the other, for the polymerase and ligase reactions respectively. PNK binds to a phosphorylated segment of XRCC1 (between its two C-terminal BRCT domains) via its Forkhead-associated (FHA) domain. We show here, contrary to previous studies, that the FHA domain of PNK binds specifically, and with high affinity to a multiply phosphorylated motif in XRCC1 containing a pSer-pThr dipeptide, and forms a 2:1 PNK:XRCC1 complex. The high-resolution crystal structure of a PNK-FHA-XRCC1 phosphopeptide complex reveals the basis for this unusual bis-phosphopeptide recognition, which is probably a common feature of the known XRCC1-associating end-processing enzymes
Architectural Education for Today’s Challenges
The changing environment in which architecture is practiced today appears very hostile in many countries
including Nigeria. There are challenges both within the profession and outside the profession. Several of these
challenges have serious implications for the training of architects in the country. This paper highlights some of
these challenges and their implications for architectural education in Nigeria. It proffers solutions aimed at
making architectural education more responsive to the evolving practice climate in Nigeria
The Higgs Mass beyond the CMSSM
The apparent discovery of a Higgs boson with mass ~125 GeV has had a
significant impact on the constrained minimal supersymmetric extension of the
Standard Model in which the scalar masses, gaugino masses and tri-linear
A-terms are assumed to be universal at the GUT scale (the CMSSM). Much of the
low-mass parameter space in the CMSSM has been excluded by supersymmetric
particle searches at the LHC as well as by the Higgs mass measurement and the
emergent signal for B_s to mu^+ mu^-. Here, we consider the impact of these
recent LHC results on several variants of the CMSSM with a primary focus on
obtaining a Higgs mass of ~125 GeV. In particular, we consider the one- and
two-parameter extensions of the CMSSM with one or both of the Higgs masses set
independently of the common sfermion mass, m_0 (the NUHM1,2). We also consider
the one-parameter extension of the CMSSM in which the input universality scale
M_in is below the GUT scale (the sub-GUT CMSSM). We find that when M_in < M_GUT
large regions of parameter space open up where the relic density of neutralinos
can successfully account for dark matter with a Higgs boson mass ~125 GeV. In
some of these regions essential roles are played by coannihilation processes
that are usually less important in the CMSSM with M_in = M_GUT. Finally, we
reconsider mSUGRA models with sub-GUT universality, which have the same number
of parameters as the CMSSM. Here too, we find phenomenologically viable regions
of parameter space, which are essentially non-existent in GUT-scale mSUGRA
models. Interestingly, we find that the preferred range of the A-term straddles
that predicted by the simplest Polonyi model.Comment: 28 pages, 12 figure
RankPL: A Qualitative Probabilistic Programming Language
In this paper we introduce RankPL, a modeling language that can be thought of
as a qualitative variant of a probabilistic programming language with a
semantics based on Spohn's ranking theory. Broadly speaking, RankPL can be used
to represent and reason about processes that exhibit uncertainty expressible by
distinguishing "normal" from" surprising" events. RankPL allows (iterated)
revision of rankings over alternative program states and supports various types
of reasoning, including abduction and causal inference. We present the
language, its denotational semantics, and a number of practical examples. We
also discuss an implementation of RankPL that is available for download
Structural change of vortex patterns in anisotropic Bose-Einstein condensates
We study the changes in the spatial distribution of vortices in a rotating
Bose-Einstein condensate due to an increasing anisotropy of the trapping
potential. Once the rotational symmetry is broken, we find that the vortex
system undergoes a rich variety of structural changes, including the formation
of zig-zag and linear configurations. These spatial re-arrangements are well
signaled by the change in the behavior of the vortex-pattern eigenmodes against
the anisotropy parameter. The existence of such structural changes opens up
possibilities for the coherent exploitation of effective many-body systems
based on vortex patterns.Comment: 5 pages, 4 figure
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