Effects of Inert Nanoparticles of High-Melting-Point Compositions on Grain Structure and Strength of Ni[3]Al Intermetallic Compounds

The paper represents experimental findings both in the area of effects of nanoparticles of inert high-melting-point TiN compounds on a Ni[3]Al intermetallic grain structure creation in the conditions of high temperature synthesis under pressure, and in the area of impact of grain structure modification on intermetallic compounds' strength factor temperature dependence. It was demonstrated that appending a stoichiometric composition of nanosized particles of high-melting-point inert chemical compounds (TiN) initiates a manyfold loss of average size of grain of Ni[3]Al intermetallic compounds, synthesized under pressure, as well as a sufficient intermetallic compounds' strength rise within a wide range of temperatures (up to 1 000 degree C). Electron-microscopic evaluations of a synthesized intermetallic structure with TiN nanoparticles, showed that, during the process of intermetallic polycrystalline structure creation from high temperature synthesis products melts, TiN nanoparticles are mainly spread throughout the boundaries and joints of grain structure, acting as stoppers of grain boundaries migration

Identifying synonymous regulatory elements in vertebrate genomes

Synonymous gene regulation, defined by regulatory elements driving shared temporal and/or spatial aspects of gene expression, is most probably predicated on genomic elements that contain similar modules of certain transcription factor binding sites (TFBS). We have developed a method to scan vertebrate genomes for evolutionary conserved modules of TFBS in a predefined configuration, and created a tool, named SynoR that identifies synonymous regulatory elements (SREs) in vertebrate genomes. SynoR performs de novo identification of SREs utilizing known patterns of TFBS in active regulatory elements (REs) as seeds for genome scans. Layers of multiple-species conservation allow the use of differential phylogenetic sequence conservation filters in search of SREs and the results are displayed such as to provide an extensive annotation of the genes containing the detected REs. Gene Ontology categories are utilized to further functionally classify the identified genes, and integrated GNF Expression Atlas 2 data allow the cataloging of tissue-specificities of the predicted SREs. SynoR is publicly available at

The gas phase cyclization of deprotonated N-aryl-2-cyano-2-diazoacetamides

The document attached has been archived with permission from the publisher.1-Aryl-4-cyano-5-hydroxy-1,2,3-triazoles can be obtained in solution by base-catalysed cyclization of N-aryl-2-cyano-2-diazoacetamides. A similar reaction was shown to take place under conditions of negative ion chemical ionization in the ion source of a mass spectrometer. High resolution mass spectrometry, tandem mass spectrometry, charge reversal spectra, synthesis of the ions with known structures and quantum chemical calculations were used to prove the latter statement. The fact of the observed cyclization demonstrates once again the ability of mass spectrometry to study the gas phase chemical reactions that take place in solution.Vladislav V. Lobodin, Yuriy Yu. Morzherin, Tom Blumenthal, Daniel Bilusich, Vladimir V. Ovcharenko, John H. Bowie, and Albert T. Lebede

Effects of Inert Nanoparticles of High-Melting-Point Compositions on Grain Structure and Strength of Ni[3]Al Intermetallic Compounds

The paper represents experimental findings both in the area of effects of nanoparticles of inert high-melting-point TiN compounds on a Ni[3]Al intermetallic grain structure creation in the conditions of high temperature synthesis under pressure, and in the area of impact of grain structure modification on intermetallic compounds' strength factor temperature dependence. It was demonstrated that appending a stoichiometric composition of nanosized particles of high-melting-point inert chemical compounds (TiN) initiates a manyfold loss of average size of grain of Ni[3]Al intermetallic compounds, synthesized under pressure, as well as a sufficient intermetallic compounds' strength rise within a wide range of temperatures (up to 1 000 degree C). Electron-microscopic evaluations of a synthesized intermetallic structure with TiN nanoparticles, showed that, during the process of intermetallic polycrystalline structure creation from high temperature synthesis products melts, TiN nanoparticles are mainly spread throughout the boundaries and joints of grain structure, acting as stoppers of grain boundaries migration

Modification of Structure and Strength Properties of Permanent Joints Under Laser Beam Welding with Application of Nanopowder Modifiers

In the paper we present the results of experimental study of specially prepared nanosize metal-ceramic compositions impact upon structure, microhardness and mechanical properties of permanent joints produced by laser-beam welding of steel and titanium alloy plates