A serious VR game for acrophobia therapy in an urban environment

Much of the costs and dangers of exposure therapy in phobia treatment can be removed through virtual reality (VR). Exposing people to heights, for instance, might sound easy, but it still involves time and money investments to reach a tall building, mountain or bridge. People suffering from milder forms of acrophobia might not even be treated at all, the cost not being worth it. This paper presents a prototype that allows exposure therapy to be done in a controlled environment, in a more comfortable, quick and cheaper way. By applying acrophobia questionnaires, collecting biophysical data and developing a virtual reality game, we can expose volunteers to heights and analyze if there is any change in their fear and anxiety levels. This way, regardless of the initial anxiety level and phobia severity, we can check if there is any post-therapy improvement and verify if virtual reality is a viable alternative to real-world exposure

Improved Outcomes with Heavy Silicone Oil in Complex Primary Retinal Detachment: A Large Multicenter Matched Cohort Study

\ua9 2023 American Academy of OphthalmologyPurpose: To establish whether Densiron 68, a heavier-than-water endotamponade agent, is an effective alternative to conventional light silicone oil in primary rhegmatogenous retinal detachment (RD) surgery for eyes with inferior breaks in the detached retina and severe proliferative vitreoretinopathy (PVR). Design: Cohort study of routinely collected data from the European Society of Retina Specialists and British and Eire Association of Vitreoretinal Surgeons vitreoretinal database between 2015 and 2022. Participants: All consecutive eyes that underwent primary rhegmatogenous RD surgery using Densiron 68 or light silicone oil as an internal tamponade agent. Methods: To minimize confounding bias, we undertook 2:1 nearest-neighbor matching on inferior breaks, large inferior rhegmatogenous RDs, PVR, and, for visual analyses, baseline visual acuity (VA) between treatment groups. We fit regression models including prognostically relevant covariates, treatment–covariate interactions, and matching weights. We used g-computation with cluster-robust methods to estimate marginal effects. For nonlinear models, we calculated confidence intervals (CIs) using bias-corrected cluster bootstrapping with 9999 replications. Main Outcome Measures: Presence of a fully attached retina and VA at least 2 months after oil removal. Results: Of 1061 eyes enrolled, 426 and 239 were included in our matched samples for anatomic and visual outcome analyses, respectively. The primary success rate was higher in the Densiron 68 group (113 of 142; 80%) compared with the light silicone oil group (180 of 284; 63%), with an adjusted odds ratio of 1.90 (95% CI, 1.63–2.23, P < 0.001). We also observed a significant improvement favoring Densiron 68 of –0.26 logarithm of the minimum angle of resolution (logMAR) in postoperative VA between the 2 groups (95% CI, –0.43 to –0.10, P = 0.002). The anatomic benefit of using Densiron 68 in eyes with inferior retinal breaks and large detachments was more pronounced among eyes with PVR grade C. We found no evidence of visual effect moderation by anatomic outcome or foveal attachment. Conclusions: Densiron achieved higher anatomic success rates and improved visual outcomes compared with conventional light silicone oil in eyes with inferior retinal pathology and severe PVR. Financial Disclosure(s): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article

What Makes Russian Women (Un)Happy? A Closer Look at the Family

Two decades of economic transition revealed that Russian women are on average less happy than men. This paper addresses individual subjective well-being from the intra-family perspective and investigates whether the gender satisfaction gap could be caused, among all, by a mismatch between the socially imposed patriarchal family gender roles and the actually performed ones. I test for the presence of the following phenomena: (1) a fair share of income brought by each of the spouses into their household is judged according to the patriarchal model attributing the role of the breadwinner to men; (2) division of housework, with women, even if working, holding the main responsibility for housekeeping activities, is perceived as fair. Prime-age working adults living in partnership constitute the dataset which is a part of the Russian Longitudinal Monitoring Survey for 1994-2004. Life satisfaction is modelled with the help of the seemingly unrelated bivariate ordered probit model aiming at the adjustment for unobserved factors influencing happiness evaluation of both partners. For the period 1994-1998, the results show that women's relative unhappiness is likely to be causes by their increasing earning powers with relative to men, and overload with hours spent on housekeeping in households with children. In the second period of economic growth, 2000 - 2004, I observe a change in women's preferences over time-use and total income shares, suggesting a tendency towards their emancipation

Effect of hyperbaric oxygen therapy in a patient with Wegener’s granulomatosis - case report

Ziarniniak Wegenera jest chorobą autoimmunologiczną, charakteryzującą się martwiczym i ziarniniakowym zapaleniem małych naczyń. Schorzenie to dotyczy górnych i dolnych dróg oddechowych, nerek, gałki ocznej. W 50% przypadków choroba zajmuje skórę, prowadząc do powstawania trudno gojących się owrzodzeń. W poniższej pracy przedstawiamy przypadek 23-letniej pacjentki, u której rozpoznano ziarniniaka Wegenera z zajęciem skóry małżowiny usznej prawej, z naciekiem na śluzówce jamy ustnej i asymetrią twarzy. W leczeniu, obok pulsów sterydowych oraz leczenia immunosupresyjnego, stosowano tlenoterapię hiperbaryczną, uzyskując bardzo dobry efekt terapeutyczny oraz całkowite ustąpienie zmian skórnych.Wegener’s granulomatosis is an autoimmune disease characterized by necrotizing granulomatous inflammation of small vessels. This condition concerns the upper and lower airways, kidneys, and eyes. In 50% of cases the disease affects skin, leading to the formation of non-healing skin ulcers. In this article, the case of a 23-year-old patient is presented who was diagnosed with Wegener’s granulomatosis on skin around the right outer ear, infiltration of the mucosa of the mouth and facial asymmetry. In treatment, apart from steroid pulses and immunosuppressive therapy, hyperbaric oxygen therapy was used, which led to a very good therapeutic effect, and total regression of skin lesions