1,385 research outputs found

    EVALUATION OF SADDLE HEIGHT IN ELITE CYCLISTS

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    Proper bike fit is essential to prevent injuries and improve performance. Especially recreational cyclists, often short on experience, rely on professional adjustment for seating position. Common bike fitting methods use formulas based on rider anthropometrics, e.g. the LeMond method (pubic symphysis height [PSH] x 0.883) (LeMond, 1988) or the Hamley method (PSH x 1.09) (Hamley et al., 1967). Pruitt (2006) recommends the correct saddle height [SH] within a knee angle [KA] of 25-35°. The purpose of this study is to verify these methods in elite men and women cyclists for today’s application

    EPOBF: Energy Efficient Allocation of Virtual Machines in High Performance Computing Cloud

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    Cloud computing has become more popular in provision of computing resources under virtual machine (VM) abstraction for high performance computing (HPC) users to run their applications. A HPC cloud is such cloud computing environment. One of challenges of energy efficient resource allocation for VMs in HPC cloud is tradeoff between minimizing total energy consumption of physical machines (PMs) and satisfying Quality of Service (e.g. performance). On one hand, cloud providers want to maximize their profit by reducing the power cost (e.g. using the smallest number of running PMs). On the other hand, cloud customers (users) want highest performance for their applications. In this paper, we focus on the scenario that scheduler does not know global information about user jobs and user applications in the future. Users will request shortterm resources at fixed start times and non interrupted durations. We then propose a new allocation heuristic (named Energy-aware and Performance per watt oriented Bestfit (EPOBF)) that uses metric of performance per watt to choose which most energy-efficient PM for mapping each VM (e.g. maximum of MIPS per Watt). Using information from Feitelson's Parallel Workload Archive to model HPC jobs, we compare the proposed EPOBF to state of the art heuristics on heterogeneous PMs (each PM has multicore CPU). Simulations show that the EPOBF can reduce significant total energy consumption in comparison with state of the art allocation heuristics.Comment: 10 pages, in Procedings of International Conference on Advanced Computing and Applications, Journal of Science and Technology, Vietnamese Academy of Science and Technology, ISSN 0866-708X, Vol. 51, No. 4B, 201

    The Molonglo Galactic Plane Survey (MGPS-2): Compact Source Catalogue

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    We present the first data release from the second epoch Molonglo Galactic Plane Survey (MGPS-2). MGPS-2 was carried out with the Molonglo Observatory Synthesis Telescope at a frequency of 843 MHz and with a restoring beam of 45 arcsec x 45 arcsec cosec(dec), making it the highest resolution large scale radio survey of the southern Galactic plane. It covers the range |b| < 10 deg and 245 deg < l < 365 deg and is the Galactic counterpart to the Sydney University Molonglo Sky Survey (SUMSS) which covers the whole southern sky with dec 10 deg). In this paper we present the MGPS-2 compact source catalogue. The catalogue has 48,850 sources above a limiting peak brightness of 10 mJy/beam. Positions in the catalogue are accurate to 1 arcsec - 2 arcsec. A full catalogue including extended sources is in preparation. We have carried out an analysis of the compact source density across the Galactic plane and find that the source density is not statistically higher than the density expected from the extragalactic source density alone. We also present version 2.0 of the SUMSS image data and catalogue which are now available online. The data consists of 629 4.3 deg x 4.3 deg mosaic images covering the 8100 deg^2 of sky with dec 10 deg. The catalogue contains 210,412 radio sources to a limiting peak brightness of 6 mJy/beam at dec -50 deg. We describe the updates and improvements made to the SUMSS cataloguing process.Comment: 12 pages, 9 figures, to be published in MNRAS Note that Figures 8 and 9 are much lower resolution than in the published versio

    Baculovirus-Mediated Expression of Human 65 kDa and 67 kDa Glutamic Acid Decarboxylases in SF9 Insect Cells and Their Relevance in Diagnosis of Insulin-Dependent Diabetes Mellitus

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    cDNAs coding for the full-length human 65 and 67 kDa glutamic acid decarboxylases (GAD65 and GAD67) were amplified from pancreas and hippocampus cDNA libraries by polymerase chain reaction, respectively. Both cDNAs were inserted into a baculovirus vector which mediated highly efficient expression of the human GAD65 and GAD67 with histidine-hexapeptides as affinity ligands at their C-termini in Spodoptera frugiperda (Sf9) cells. The recombinant GAD proteins were purified to homogeneity by affinity chromatography using a metal-chelating matrix. The infected Sf9 insect cells expressed the recombinant human GAD65 and GAD67 with natural-like conformations, as confirmed by measurement of their enzyme activities as well as their fully restored autoantigenicities. Immunoprecipitation of metabolically labeled infected Sf9 cells demonstrated the autoantigenic potential of the recombinant GAD proteins. The practicability of using recombinant GAD65 and GAD67 derived from the baculovirus expression system for the development of an immunoassay for the diagnosis of insulin-dependent diabetes mellitus is discussed

    Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II

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    By using an immunoprecipitation assay, we analysed reactivity of autoantibodies to human recombinant GAD65 and GAD67 in sera from patients with autoimmune polyendocrine syndrome Type II (APS II) with and without Type 1 (insulin-dependent) diabetes mellitus (IDDM) compared to patients with organ-specific autoimmunity. Overall antibodies to GAD65 were correlated with IDDM in all study groups, whereas GAD67 antibodies were associated with IDDM when APS II coexists. Antibodies to GAD65 and GAD67 were detected in 13 (44.8%) and 7 (24.1%) out of 29 APS II patients with IDDM, but in only 4 (13.8%) and 2 (6.9%) out of 29 APS II patients without IDDM, respectively (p < 0.05). In short-standing IDDM (< 1 year), antibodies to GAD67 were significantly more frequent in patients with APS II (5 of 9 [55.6%] subjects) compared to matched diabetic patients without coexisting polyendocrinopathy (1 of 18 [5.6%] subjects) (p < 0.02). The levels of GAD65 (142 ± 90 AU) and GAD67 antibodies (178 ± 95 AU) were significantly higher in patients with polyglandular disease than in patients with isolated IDDM (91 ± 85 AU and 93 ± 57 AU) (p < 0.02). Interestingly, all 11 GAD67 antibody positive subjects also had GAD65 antibodies (p < 0.0001), and in 10 of 11 anti-GAD67 positive sera the GAD67 antibodies could be blocked by either GAD67 or GAD65, suggesting the presence of cross-reactive autoantibodies. No correlation was observed between GAD antibodies and age, sex or any particular associated autoimmune disease, besides IDDM. GAD antibodies were present in only 1 of 6 (16.7%) patients with APS Type I, in 1 of 26 (3.9%) patients with autoimmune thyroid disease but in none of the patients with Addison's disease (n = 16), pernicious anaemia (n = 7) or normal controls (n = 50). Our data suggest distinct antibody specificities reactive to GAD isoforms in APS II and IDDM, which might reflect different mechanisms of autoimmune response in IDDM with coexisting autoimmune polyendocrine autoimmunity

    Time Series Analysis of Garment Distributions Via Street Webcam

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    An Exit Burr Model for Drilling of Metals

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