Stretchable Dual-Capacitor Multi-Sensor for Touch-Curvature-Pressure-Strain Sensing

We introduce a new type of multi-functional capacitive sensor that can sense several different external stimuli. It is fabricated only with polydimethylsiloxane (PDMS) films and silver nanowire electrodes by using selective oxygen plasma treatment method without photolithography and etching processes. Differently from the conventional single-capacitor multi-functional sensors, our new multifunctional sensor is composed of two vertically-stacked capacitors (dual-capacitor). The unique dual-capacitor structure can detect the type and strength of external stimuli including curvature, pressure, strain, and touch with clear distinction, and it can also detect the surface-normal directionality of curvature, pressure, and touch. Meanwhile, the conventional single-capacitor sensor has ambiguity in distinguishing curvature and pressure and it can detect only the strength of external stimulus. The type, directionality, and strength of external stimulus can be determined based on the relative capacitance changes of the two stacked capacitors. Additionally, the logical flow reflected on a tree structure with its branches reaching the direction and strength of the corresponding external stimulus unambiguously is devised. This logical flow can be readily implemented in the sensor driving circuit if the dual-capacitor sensor is commercialized actually in the future

Effects of small pulsed nanocurrents on cell viability in vitro and in vivo: implications for biomedical electrodes

Using a custom-built, implantable pulse generator, we studied the effects of small pulsed currents on the viability on rat aortic-derived cells (RAOC) in vitro. The pulsed currents (0.37A/m(2)) underwent apoptosis within 24h as shown by the positive staining for cleaved caspase-3 and classically apoptotic morphology. Based on these findings, we examined the effects of nanocurrents in vivo. The pulse generator was implanted subcutaneously in the rat model. The electrode|tissue interface histology revealed no difference between the active platinum surface and the neighboring control surface, however we found a large difference between electrodes that were functional during the entire experiment and non-active electrodes. These non-active electrodes showed an increase in impedance at higher frequencies 21 days post-implantation, whereas working electrodes retained their impedance value for the entire experiment. These results indicate that applied currents can reduce the impedance of implanted electrodes

Fully Untethered Battery-free Biomonitoring Electronic Tattoo with Wireless Energy Harvesting

Bioelectronics stickers that interface the human epidermis and collect electrophysiological data will constitute important tools in the future of healthcare. Rapid progress is enabled by novel fabrication methods for adhesive electronics patches that are soft, stretchable and conform to the human skin. Yet, the ultimate functionality of such systems still depends on rigid components such as silicon chips and the largest rigid component on these systems is usually the battery. In this work, we demonstrate a quickly deployable, untethered, battery-free, ultrathin (~5 μm) passive "electronic tattoo" that interfaces with the human skin for acquisition and transmission of physiological data. We show that the ultrathin film adapts well with the human skin, and allows an excellent signal to noise ratio, better than the gold-standard Ag/AgCl electrodes. To supply the required energy, we rely on a wireless power transfer (WPT) system, using a printed stretchable Ag-In-Ga coil, as well as printed biopotential acquisition electrodes. The tag is interfaced with data acquisition and communication electronics. This constitutes a "data-by-request" system. By approaching the scanning device to the applied tattoo, the patient's electrophysiological data is read and stored to the caregiver device. The WPT device can provide more than 300 mW of measured power if it is transferred over the skin or 100 mW if it is implanted under the skin. As a case study, we transferred this temporary tattoo to the human skin and interfaced it with an electrocardiogram (ECG) device, which could send the volunteer's heartbeat rate in real-time via Bluetooth