Spontaneous Magnetisation in a Quantum Wire

An existence of predominant symmetrical spin configuration (spin polarised phase) and "diluted" density of states (pseudo-gap) in a layer under the Fermi level in a quantum wire is predicted. The condition of cross-over from non-polarised phase to polarised one was derived. The transition occurs for sufficiently low electron density in a wire and is accompanied by an acute decrease of electron density of states near the Fermi level.It may result in a corresponding decrease of conductance. A similar effect may exist in a two-dimensional electron gas.Comment: 8 pages, 1 figur

Dietology elective course as an element of implementing a healthy way of life for prospective physicians

The article presents the results of mastering the dietology elective course by 6-year students of the faculty of general medicine.В статье представлен анализ результатов освоения программы электива по диетологии студентами 6 курса лечебно-профилактического факультет

Hidden Markov Model Analysis of Maternal Behavior Patterns in Inbred and Reciprocal Hybrid Mice

Individual variation in maternal care in mammals shows a significant heritable component, with the maternal behavior of daughters resembling that of their mothers. In laboratory mice, genetically distinct inbred strains show stable differences in maternal care during the first postnatal week. Moreover, cross fostering and reciprocal breeding studies demonstrate that differences in maternal care between inbred strains persist in the absence of genetic differences, demonstrating a non-genetic or epigenetic contribution to maternal behavior. In this study we applied a mathematical tool, called hidden Markov model (HMM), to analyze the behavior of female mice in the presence of their young. The frequency of several maternal behaviors in mice has been previously described, including nursing/grooming pups and tending to the nest. However, the ordering, clustering, and transitions between these behaviors have not been systematically described and thus a global description of maternal behavior is lacking. Here we used HMM to describe maternal behavior patterns in two genetically distinct mouse strains, C57BL/6 and BALB/c, and their genetically identical reciprocal hybrid female offspring. HMM analysis is a powerful tool to identify patterns of events that cluster in time and to determine transitions between these clusters, or hidden states. For the HMM analysis we defined seven states: arched-backed nursing, blanket nursing, licking/grooming pups, grooming, activity, eating, and sleeping. By quantifying the frequency, duration, composition, and transition probabilities of these states we were able to describe the pattern of maternal behavior in mouse and identify aspects of these patterns that are under genetic and nongenetic inheritance. Differences in these patterns observed in the experimental groups (inbred and hybrid females) were detected only after the application of HMM analysis whereas classical statistical methods and analyses were not able to highlight them

Structure of herd immunity to SARS-COV-2 in the Krasnoyarsk region population in the COVID-19 epidemic

Purpose. Determination of the SARS-CoV-2 population humoral immunity among the population of the Krasnoyarsk Territory during the COVID-19 epidemic.Materials and methods. The study was carried out as a part of project for assessing population immunity to SARS-CoV-2 among the population of Russian Federation using unified methodology developed by Rospotrebnadzor, with the participation of the Research Institute for Epidemiology and Microbiology named by Pasteur, and taking into account the recommendations of the WHO. The work involved 2907 volunteers, selected by the online survey and randomization by age and territory. All volunteers were divided into 7 age groups: 1–17, 18–29, 30–39, 40–49, 50–59, 60–69, 70 and older (70+), including a total 246–449 people. Population immunity testing was carried out during the formation of groups (1st stage), and then twice more, with the interval of 6–8 weeks. Serum was obtained from venous blood samples obtained from volunteers, in which antibodies to the SARS-CoV-2 nucleocapsid were determined by the enzyme immunoassay. The results were analyzed by methods of nonparametric statistics: median, interquartile range, rank correlation coefficient were calculated in the Excel statistical package. The confidence interval to seroprevalence indicators (95% CI) was calculated using the WinPepi statistical package (version 11.65). The statistical significance of the differences was assessed with a probability level of p ≤ 0.05.Results. The seroprevalence of the population of the Krasnoyarsk Territory during the 5-month period of seromonitoring had increased 3.3 times from 12.8% (95% CI 11.3–14.4) to 41.7% (95% CI 39.4–4.0) , while the grouping by age had not revealed any peculiarities throughout the study. The trend towards a decrease in the incidence was formed on the 6th week of 2021. The seroprevalence of convalescents after COVID-19 during the initial testing was 61.5% (95% CI 40,6–79.8), among those who were in contact with patients with COVID-19 or convalescents –23.8% (95% CI 13.9–36.2) . Among the volunteers, 347 seropositive persons were identified, 324 of which were observed asymptomatic course.Conclusion. The structure of the population humoral immunity to SARS-CoV-2 of he population of the Krasnoyarsk Territory has been investigated. It was found that an increase in seroprevalence to 41.7% (95% CI 39.4–4.0) was accompanied by a decrease in morbidity

Clinical cases as professional skills and qualifications assessment in a patient – physician - medical insurance expert communication simulation

Внедрение требований Федеральных государственных образовательных стандартов (ФГОС) в подготовку врачей требует разработки инструментов оценки овладения профессиональными компетенциями студентами выпускного курса [2]. Адекватная оценка достижений студента в рамках образовательного процесса с использованием концепции компетентностного подхода, адаптированного к реальным условиям клинической практики, с которыми столкнётся молодой врач в первые часы своей самостоятельной работы представляется крайне важно

5-year students initiating hospital therapy study course baseline knowledge level assessment

The article describes the results of the evaluation of the necessary for mastering the hospital therapy course basic knowledge level of the 5-year general medicine faculty students of the Ural State Medical University. The evaluation was performed by an incoming testing. The average correct answers percentage was 77%. The assessment helped identify the most difficult questions for the students. The issues identified will be the basis for correction measures to optimize the discipline teaching.В статье рассмотрены результаты оценки исходного уровня знаний студентов 5 курса лечебно-профилактического факультета УГМУ, необходимых для освоения дисциплины «Госпитальная терапия». Оценку проводили методом входящего тестирования. Средний процент верных ответов составил 77. Выявлены наиболее сложные для студентов вопросы, требующие разработки и проведения корректирующих мероприятий для оптимизации преподавания госпитальной терапии

Assessment of the baseline knowledge level of 5-year students initiating hospital therapy study course

The article describes the results of the evaluation of the necessary for mastering the hospital therapy course basic knowledge level of the 5-year general medicine faculty students of the Ural state medical university. The evaluation was performed by an incoming testing. The average correct answers percentage was 77%. The assessment helped identify the most difficult questions for the students. The issues identified will be discussed during practical classes and lectures on the disciplineВ статье рассмотрены результаты оценки исходного уровня знаний студентов 5 курса лечебно-профилактического факультета УГМУ, необходимых для освоения дисциплины «Госпитальная терапия». Оценку проводили методом входящего тестирования. Средний процент верных ответов составил 77%. Выявлены наиболее сложные для студентов вопросы, которые будут дополнительно разбираться на практических занятиях и лекциях по госпитальной терапии

Students’ assessment of the hospital therapy lecture course which has been performed before the new coronavirus COVID-19 pandemia

The results of an anonymous 6th year medical students voluntary Google forms survey are discussed. All students had completed the core "Hospital therapy" study course by the survey date. 20 questions were offered to evaluate students opinions about the lecture course of the studied discipline. The analysis of the survey results allowed us to develop directions for optimizing the lecture teaching mode at the Urals State Medical University.В статье рассмотрены результаты анонимного добровольного анкетирования с помощью «гугл-опросника» студентов 6 курса лечебно-профилактического факультета УГМУ, завершивших изучение основного курса дисциплины «Госпитальная терапия». Студентам было предложено 20 вопросов для оценки мнения студентов о лекционном курсе изученной дисциплины. Анализ результатов опроса позволил выработать направления оптимизации лекционной формы преподавания в медицинском вузе

The introduction of score-rating system of evaluating achievements of students on discipline "hospital therapy"

The article presents the score-rating system of evaluation of achievements of students in the department of hospital therapy.В статье представлена балльно-рейтинговая система оценки достижений студентов на кафедре госпитальной терапии

Assessment of the professional competence of the 5- and 6-year studentsof the faculty of general medicine in the course of studying hospital therapy

The article presents the results of the analysis of mastering the professional competencies of 5- and 6-year students of the faculty of general medicine for the period from 2016 to 2018.В статье представлены результаты анализа овладения профессиональными компетенциями студентов 5-6 курсов лечебно-профилактического факультета за период с 2016 по 2018 гг