Cardiac reserve during weightlessness simulation and shuttle flight

Bedrest deconditioning is suspected to reduce cardiac function. However, quantitation of subtle decreases in cardiac reserve may be difficult. Normal subjects show considerable variability in heart rate response, reflected by a relatively broadband interbeat interval power spectrum. We hypothesized that the deconditioning effects of bedrest would induce narrowing of this spectrum, reflecting a reduction in the autonomically-modulated variability in heart rate. Ten aerobically conditioned men (average 35-50 years) underwent orthostatic tolerance testing with lower body negative pressure pre-bedrest and after 10 days of bedrest, while on placebo and after intravenous atropine. Spectra were derived by Fourier analysis of 128 interbeat interval data sets from subjects with sufficient numbers of beats during matched periods of the protocol. Data suggest that atropine unmasks the deconditioning effect of bedrest in athletic men, evidenced by a reduction in interbeat interval spectral power compared with placebo. Spectral analysis offers a new means of quantitating the effects of bedrest deconditioning and autonomic perturbations on cardiac dynamics

Modern Dynamical Coupled-Channels Calculations for Extracting and Understanding the Nucleon Spectrum

We give an overview of recent progress in the spectroscopic study of nucleon resonances within the dynamical coupled-channels analysis of meson-production reactions. The important role of multichannel reaction dynamics in understanding various properties of nucleon resonances is emphasized.Comment: 11 pages, 8 figures. Plenary talk at The 14th International Conference on Meson-Nucleon Physics and the Structure of the Nucleon (MENU2016), Kyoto, Japan, July 25-30, 201

Dynamical Entanglement in Particle Scattering

This paper explores the connections between particle scattering and quantum information theory in the context of the non-relativistic, elastic scattering of two spin-1/2 particles. An untangled, pure, two-particle in-state is evolved by an S-matrix that respects certain symmetries and the entanglement of the pure out-state is measured. The analysis is phrased in terms of unitary, irreducible representations (UIRs) of the symmetry group in question, either the rotation group for the spin degrees of freedom or the Galilean group for non-relativistic particles. Entanglement may occurs when multiple UIRs appear in the direct sum decomposition of the direct product in-state, but it also depends of the scattering phase shifts. \keywords{dynamical entanglement, scattering, Clebsch-Gordan methods}Comment: 6 pages, submitted to Int. J. Mod. Phys. A as part of MRST 2005 conference proceeding

Classical Three-Box "paradox"

A simple classical probabilistic system (a simple card game) classically exemplifies Aharonov and Vaidman's "Three-Box 'paradox'" [J. Phys. A 24, 2315 (1991)], implying that the Three-Box example is neither quantal nor a paradox and leaving one less difficulty to busy the interpreters of quantum mechanics. An ambiguity in the usual expression of the retrodiction formula is shown to have misled Albert, Aharonov, and D'Amato [Phys. Rev. Lett. 54, 5 (1985)] to a result not, in fact, "curious"; the discussion illustrates how to avoid this ambiguity.Comment: 10 pages. v4: As published, with corrections and updated reference

The Delocalized Effective Degrees of Freedom of a Black Hole at Low Frequencies

Identifying the fundamental degrees of freedom of a black hole poses a long-standing puzzle. In hep-th/0511133 Goldberger and Rothstein forwarded a theory of the low frequency degrees of freedom within the effective field theory approach, where they are relevancy-ordered but of unclear physical origin. Here these degrees of freedom are identified with near-horizon but non-compact gravitational perturbations which are decomposed into delocalized multipoles. Their world-line (kinetic) action is determined within the classical effective field theory (CLEFT) approach and their interactions are discussed. The case of the long-wavelength scattering of a scalar wave off a Schwarzschild black hole is treated in some detail, interpreting within the CLEFT approach the equality of the leading absorption cross section with the horizon area.Comment: 8 pages. Awarded fifth prize in the 2008 Gravity Research Foundation essay contest. v2: minor change

Natural entropy fluctuations discriminate similar looking electric signals emitted from systems of different dynamics

Complexity measures are introduced, that quantify the change of the natural entropy fluctuations at different length scales in time-series emitted from systems operating far from equilibrium. They identify impending sudden cardiac death (SD) by analyzing fifteen minutes electrocardiograms, and comparing to those of truly healthy humans (H). These measures seem to be complementary to the ones suggested recently [Phys. Rev. E {\bf 70}, 011106 (2004)] and altogether enable the classification of individuals into three categories: H, heart disease patients and SD. All the SD individuals, who exhibit critical dynamics, result in a common behavior.Comment: Published in Physical Review

Multifractality and scale invariance in human heartbeat dynamics

Human heart rate is known to display complex fluctuations. Evidence of multifractality in heart rate fluctuations in healthy state has been reported [Ivanov et al., Nature {\bf 399}, 461 (1999)]. This multifractal character could be manifested as a dependence on scale or beat number of the probability density functions (PDFs) of the heart rate increments. On the other hand, scale invariance has been recently reported in a detrended analysis of healthy heart rate increments [Kiyono et al., Phys. Rev. Lett. {\bf 93}, 178103 (2004)]. In this paper, we resolve this paradox by clarifying that the scale invariance reported is actually exhibited by the PDFs of the sum of detrended healthy heartbeat intervals taken over different number of beats, and demonstrating that the PDFs of detrended healthy heart rate increments are scale dependent. Our work also establishes that this scale invariance is a general feature of human heartbeat dynamics, which is shared by heart rate fluctuations in both healthy and pathological states

Emergence of Complex Dynamics in a Simple Model of Signaling Networks

A variety of physical, social and biological systems generate complex fluctuations with correlations across multiple time scales. In physiologic systems, these long-range correlations are altered with disease and aging. Such correlated fluctuations in living systems have been attributed to the interaction of multiple control systems; however, the mechanisms underlying this behavior remain unknown. Here, we show that a number of distinct classes of dynamical behaviors, including correlated fluctuations characterized by $1/f$-scaling of their power spectra, can emerge in networks of simple signaling units. We find that under general conditions, complex dynamics can be generated by systems fulfilling two requirements: i) a ``small-world'' topology and ii) the presence of noise. Our findings support two notable conclusions: first, complex physiologic-like signals can be modeled with a minimal set of components; and second, systems fulfilling conditions (i) and (ii) are robust to some degree of degradation, i.e., they will still be able to generate $1/f$-dynamics

How to reconcile the Rosenbluth and the polarization transfer method in the measurement of the proton form factors

The apparent discrepancy between the Rosenbluth and the polarization transfer method for the ratio of the electric to magnetic proton form factors can be explained by a two-photon exchange correction which does not destroy the linearity of the Rosenbluth plot. Though intrinsically small, of the order of a few percent of the cross section, this correction is kinematically enhanced in the Rosenbluth method while it is small for the polarization transfer method, at least in the range of (Q^2) where it has been used until now.Comment: 4 pages, 4 figures. Version accepted for publication in Phys. Rev. Let

Effective Field Theory and Unification in AdS Backgrounds

This work is an extension of our previous work, hep-th/0204160, which showed how to systematically calculate the high energy evolution of gauge couplings in compact AdS_5 backgrounds. We first directly compute the one-loop effects of massive charged scalar fields on the low energy couplings of a gauge theory propagating in the AdS background. It is found that scalar bulk mass scales (which generically are of order the Planck scale) enter only logarithmically in the corrections to the tree-level gauge couplings. As we pointed out previously, we show that the large logarithms that appear in the AdS one-loop calculation can be obtained within the confines of an effective field theory, by running the Planck brane correlator from a high UV matching scale down to the TeV scale. This result exactly reproduces our previous calculation, which was based on AdS/CFT duality. We also calculate the effects of scalar fields satisfying non-trivial boundary conditions (relevant for orbifold breaking of bulk symmetries) on the running of gauge couplings.Comment: LaTeX, 27 pages; minor typos fixed, comments adde