23 research outputs found
Effect of Feeding Transcarpathian Zeolite on Gastrointestinal Morphology and Function in Broiler Chickens
Comparative effects of sodium butyrate and flavors on feed intake of lactating sows and growth performance of piglets
Expression of alpha-smooth muscle actin as special and morphometric assessment in the small intestine during the postnatal development in hamster
Encapsulation of tributyrin by gamma‐cyclodextrin: Complexation, spray drying, and in vitro
Electron microscopy finder-grids link quantitative cytometry with high-resolution confocal imaging in the study of TGF-beta 1 expression in the small intestine mucosa in growing pigs
A new method is proposed linking the high-throughput quantitative population analysis with high-resolution imaging systems. Samples from piglet small intestine labelled against transforming growth factor β1 (TGF-β1) were overlayed with electron microscopy finder-grids and scanned by SCAN^R scanning cytometer. From the tissue map generated by SCAN^R, regions of interest (ROI) with TGF-β1-positive cells were selected and their coordinates stored from the sample overview. ROI were then located under the confocal microscope enabling detail visualization of the pattern of intracellular localization of the studied cytokine.4 page(s
Volatile Retention and Morphological Properties of Microencapsulated Tributyrin Varied by Wall Material and Drying Method
The effect of tributyrin supplementation to milk replacer on plasma glucagon‐like peptide 2 concentrations in pre‐weaning calves
Effect of sodium butyrate supplementation in milk replacer and starter diet on rumen development in calves
Importance of release location on the mode of action of butyrate derivatives in the avian gastrointestinal tract
In the field of animal nutrition, butyrate is used as a zootechnical ingredient and can be used as an unprotected salt or in the form of protected derivatives such as butyrate glycerides or butyrate-loaded matrices. Dietary butyrate supplementation has been shown to improve growth performance and resilience of broiler chickens through distinct mechanisms, operating on both eukaryotic and prokaryotic cells. Firstly, butyrate influences endogenous avian cells in multiple ways: it is an agonist of free-fatty acid receptors, an inhibitor of pro-inflammatory pathways, an epigenetic modulating agent and acts as an energy source. Secondly, butyrate influences the microbiota residing in the avian gastrointestinal tract (GIT) as a result of its bacteriostatic properties. The responses, e.g. changes in growth performance, gut morphology, carcass traits or nutrient digestibility of chickens, to dietary butyrate supplementation are inconsistent with factors such as additive inclusion level, diet composition, age and health status of the bird modulating the effects of butyrate and its derivatives. For many derivatives, the precise GIT segment wherein butyrate is released is unclear. Release location may affect the observed responses to butyrate given the diversity of cell types and pH conditions encountered throughout the gastrointestinal tract of poultry, and the differences in microbiota composition in the different gut segments. As a consequence, our understanding of the mode of action of butyrate is hampered. Characterisation of existing derivatives and development of targeted-release formulations are, therefore, important to gain insight in the different physiological effects butyrate can elicit in broiler chickens