On alpha stable distribution of wind driven water surface wave slope

We propose a new formulation of the probability distribution function of wind driven water surface slope with an $\alpha$-stable distribution probability. The mathematical formulation of the probability distribution function is given under an integral formulation. Application to represent the probability of time slope data from laboratory experiments is carried out with satisfactory results. We compare also the $\alpha$-stable model of the water surface slopes with the Gram-Charlier development and the non-Gaussian model of Liu et al\cite{Liu}. Discussions and conclusions are conducted on the basis of the data fit results and the model analysis comparison.Comment: final version of the manuscript: 25 page

Public Health Response to Imported Case of Poliomyelitis, Australia, 2007

Inactivated polio vaccine was offered, and the index case-patient and household contacts were quarantined

Longitudinal Changes in Health-Related Quality of Life in Primary Glomerular Disease: Results From the CureGN Study

© 2020 Introduction: Prior cross-sectional studies suggest that health-related quality of life (HRQOL) worsens with more severe glomerular disease. This longitudinal analysis was conducted to assess changes in HRQOL with changing disease status. Methods: Cure Glomerulonephropathy (CureGN) is a cohort of patients with minimal change disease, focal seNorthwell Healthntal glomerulosclerosis, membranous nephropathy, IgA vasculitis, or IgA nephropathy. HRQOL was assessed at enrollment and follow-up visits 1 to 3 times annually for up to 5 years with the Patient-Reported Outcomes Measurement Information System (PROMIS). Global health, anxiety, and fatigue domains were measured in all; mobility was measured in children; and sleep-related impairment was measured in adults. Linear mixed effects models were used to evaluate HRQOL responsiveness to changes in disease status. Results: A total of 469 children and 1146 adults with PROMIS scores were included in the analysis. HRQOL improved over time in nearly all domains, though group-level changes were modest. Edema was most consistently associated with worse HRQOL across domains among children and adults. A greater number of symptoms also predicted worse HRQOL in all domains. Sex, age, obesity, and serum albumin were associated with some HRQOL domains. The estimated glomerular filtration rate (eGFR) was only associated with fatigue and adult physical health; proteinuria was not associated with any HRQOL domain in adjusted models. Conclusion: HRQOL measures were responsive to changes in disease activity, as indicated by edema. HRQOL over time was not predicted by laboratory-based markers of disease. Patient-reported edema and number of symptoms were the strongest predictors of HRQOL, highlighting the importance of the patient experience in glomerular disease. HRQOL outcomes inform understanding of the patient experience for children and adults with glomerular diseases

Memorials to the victims of Nazism: the impact on tourists in Berlin

This qualitative study explores tourist responses to memorials to the victims of Nazism in Berlin and the impact they have on the tourist experience. The findings are located in the field of study known as dark tourism, of which visiting memorials is a part. The analysis shows that tourists increased their knowledge of the crimes committed by the Nazis, thus fulfilling the educational function of memorials. Tourists were also overwhelmed by their experience; they attested to feelings of sadness, shock, anger, despair and incomprehension. These feelings made it hard for them to resume the role of tourist after their exposure to a memorial. There was acknowledgement of the extent of commemoration practised in Germany

Adorno on Hope

I argue that Theodor W. Adorno’s philosophy articulates a radical conception of hope. According to Lear, radical hope is ‘directed toward a future goodness that transcends the current ability to understand what it is’ (2006:103). Given Adorno’s claim that the current world is radically evil, and that we cannot know or even imagine what the good is, it is plausible that his conception of hope must be radical in this sense. I develop this argument through an analysis of (i) Adorno’s engagement with Kant’s conception of hope, (ii) Adorno’s references to hope, and (iii) his critical diagnosis of a metaphysical need for hope. Having demonstrated that Adorno must reject both ordinary and Kantian hope, I examine why Adorno thinks that we still may have reasons for hope. I also show that Adorno’s conception of hope differs from Lear’s in one important respect

Seroepidemiology of coxsackievirus A6, coxsackievirus A16, and Enterovirus 71 infections among children and adolescents in Singapore, 2008-2010

10.1371/journal.pone.0127999PLoS ONE105e012799

Depressive Symptoms in Children with Chronic Kidney Disease

To assess depression in children with chronic kidney disease (CKD) and to determine associations with patient characteristics, intellectual and educational levels, and health related quality of life (HRQoL)