Gender differences in self-assessed health-related quality of life in children with atopic dermatitis

Background: Atopic dermatitis has a significant impact on quality of life of children and families. Objective: It is important to assess gender differences in health-related quality of life in children with atopic dermatitis in order to effectively use health-related quality of life results. Methods: Children 5- to 16-years of age with atopic dermatitis from Italy, Singapore, Czech Republic, and Ukraine were divided into two groups (boys and girls). Each child in the group of boys was matched to a corresponding child in the group of girls from the same country whose age and scoring atopic dermatitis value were almost identical. Self-assessed health-related quality of life was measured by the Children's Dermatology Life Quality Index. Results: The difference in overall Children's Dermatology Life Quality Index between boys and girls was not significant (P=0.33). Girls with atopic dermatitis assessed Children's Dermatology Life Quality Index item on embarrassment significantly higher (0.78±0.93 for boys and 1.14±0.93 for girls, p<0.05). Lowest scored items were the same and overall Children's Dermatology Life Quality Index results significantly correlated with scoring atopic dermatitis values in both groups. Two separate Children's Dermatology Life Quality Index items in boys and five items in girls significantly correlated with atopic dermatitis severity. The Children's Dermatology Life Quality Index item on affected sleep significantly correlated with the age of boys (r=0.38, P=0.02) and another Children's Dermatology Life Quality Index item on school work/holiday with the age of girls (r=0.59, p<0.01). Conclusion: Despite that the authors did not find differences in overall health-related quality of life results, girls were more embarrassed, self-conscious, upset, and sad because of atopic dermatitis. The authors' results may influence the educational part of consultations of children with atopic dermatitis

An international multicenter study on quality of life and family quality of life in children with atopic dermatitis

10.4103/0378-6323.104669Indian Journal of Dermatology, Venereology and Leprology79152-5

Timing resolution studies of the optical part of the AFP Time-of-flight detector

We present results of the timing performance studies of the optical part and front-end electronics of the time-of-flight subdetector prototype for the ATLAS Forward Proton (AFP) detector obtained during the test campaigns at the CERN-SPS test-beam facility (120 GeV $\pi ^+$ particles) in July 2016 and October 2016. The time-of-flight (ToF) detector in conjunction with a 3D silicon pixel tracker will tag and measure protons originating in central exclusive interactions $p + p \rightarrow p + X + p$, where the two outgoing protons are scattered in the very forward directions. The ToF is required to reduce so-called pileup backgrounds that arise from multiple proton interactions in the same bunch crossing at high luminosity. The background can fake the signal of interest, and the extra rejection from the ToF allows the proton tagger to operate at the high luminosity required for the measurement of the processes. The prototype detector uses fused silica bars emitting Cherenkov radiation as a relativistic particle passes through them. The emitted Cherenkov photons are detected by a multi-anode micro-channel plate photomultiplier tube (MCP-PMT) and processed by fast electronics

Beam tests of an integrated prototype of the ATLAS Forward Proton detector

The ATLAS Forward Proton (AFP) detector is intended to measure protons scattered at small angles from the ATLAS interaction point. To this end, a combination of 3D Silicon pixel tracking modules and Quartz-Cherenkov time-of-flight (ToF) detectors is installed 210m away from the interaction point at both sides of ATLAS. Beam tests with an AFP prototype detector combining tracking and timing sub-detectors and a common readout have been performed at the CERN-SPS test-beam facility in November 2014 and September 2015 to complete the system integration and to study the detector performance. The successful tracking-timing integration was demonstrated. Good tracker hit efficiencies above 99.9% at a sensor tilt of 14{\deg}, as foreseen for AFP, were observed. Spatial resolutions in the short pixel direction with 50 {\mu}m pitch of 5.5 +/- 0.5 {\mu}m per pixel plane and of 2.8 +/- 0.5 {\mu}m for the full four-plane tracker at 14{\deg} were found, largely surpassing the AFP requirement of 10 {\mu}m. The timing detector showed also good hit efficiencies above 99%, and a full-system time resolution of 35 +/- 6 ps was found for the ToF prototype detector with two Quartz bars in-line (half the final AFP size) without dedicated optimisation, fulfilling the requirements for initial low-luminosity AFP runs.The ATLAS Forward Proton (AFP) detector is intended to measure protons scattered at small angles from the ATLAS interaction point. To this end, a combination of 3D Silicon pixel tracking modules and Quartz-Cherenkov time-of-flight (ToF) detectors is installed 210 m away from the interaction point at both sides of ATLAS. Beam tests with an AFP prototype detector combining tracking and timing sub-detectors and a common readout have been performed at the CERN-SPS test-beam facility in November 2014 and September 2015 to complete the system integration and to study the detector performance. The successful tracking-timing integration was demonstrated. Good tracker hit efficiencies above 99.9% at a sensor tilt of 14°, as foreseen for AFP, were observed. Spatial resolutions in the short pixel direction with 50 μm pitch of 5.5 ± 0.5 μm per pixel plane and of 2.8 ± 0.5 μm for the full four-plane tracker at 14° were found, largely surpassing the AFP requirement of 10 μm. The timing detector showed also good hit efficiencies above 99%, and a full-system time resolution of 35±6 ps was found for the ToF prototype detector with two Quartz bars in-line (half the final AFP size) without dedicated optimisation, fulfilling the requirements for initial low-luminosity AFP runs.The ATLAS Forward Proton (AFP) detector is intended to measure protons scattered at small angles from the ATLAS interaction point. To this end, a combination of 3D Silicon pixel tracking modules and Quartz-Cherenkov time-of-flight (ToF) detectors is installed 210m away from the interaction point at both sides of ATLAS. Beam tests with an AFP prototype detector combining tracking and timing sub-detectors and a common readout have been performed at the CERN-SPS test-beam facility in November 2014 and September 2015 to complete the system integration and to study the detector performance. The successful tracking-timing integration was demonstrated. Good tracker hit efficiencies above 99.9% at a sensor tilt of 14{\deg}, as foreseen for AFP, were observed. Spatial resolutions in the short pixel direction with 50 {\mu}m pitch of 5.5 +/- 0.5 {\mu}m per pixel plane and of 2.8 +/- 0.5 {\mu}m for the full four-plane tracker at 14{\deg} were found, largely surpassing the AFP requirement of 10 {\mu}m. The timing detector showed also good hit efficiencies above 99%, and a full-system time resolution of 35 +/- 6 ps was found for the ToF prototype detector with two Quartz bars in-line (half the final AFP size) without dedicated optimisation, fulfilling the requirements for initial low-luminosity AFP runs

Construction of the optical part of a time-of-flight detector prototype for the AFP detector

We present the construction of the optical part of the ToF (time-of-flight) subdetector prototype for the AFP (ATLAS Forward Proton) detector. The ToF detector in conjunction with a 3D silicon pixel tracker will tag and measure protons originating in central exclusive interactions p + p → p + X + p, where the two outgoing protons are scattered in the very forward directions. The ToF is required to reduce so-called pileup backgrounds that arise from multiple proton interactions in the same bunch crossing at high luminosity. The background can fake the signal of interest, and the extra rejection from the ToF allows the proton tagger to operate at the high luminosity required for measurement of the processes. The prototype detector uses fused silica bars emitting Cherenkov radiation as a relativistic particle passes through it. The emitted Cherenkov photons are detected by a micro-channel plate multi-anode Photomultiplier Tube (MCP-PMT) and processed by fast electronics

An insight on the speciation and genetical imprint of bicarbonate ion in the groundwater along K/T boundary, South India

Groundwater stored in sand, clay, and underground rocks that act as huge aquifers of water have been vastly explored by human civilization for drinking and irrigation purposes. This underlying sand, clay, and rocks greatly influence the chemistry of groundwater by fluctuation in various concentrations of ions. The geochemistry of Ariyalur region was studied by taking 142 samples in both Pre monsoon (PRM) and Post monsoon (POM) seasons. Analysis for crucial cations and anions like K+, Na+, F-, Cl-, HCO3-, Mg2+, Ca2+, SO42-, PO43-, NO3-, and H4SiO4and the physico-chemical variables like pH, total dissolved solid (TDS), and electrical conductivity (EC) were carried out to understand the suitability of groundwater. From all these information, Piper-plot has been used to analyze the water type in both the seasons. The study revealed that in both the seasons, HCO3-covers the major factors followed by H2CO3which are responsible for the change of chemistry of groundwater and proved its importance in the study area. Hence to determine the relationship of HCO3-with other ions, various charts were used. To obtain the origin of this HCO3-and reactions related to it, correlation of different species like HCO3, CaHCO3, MgHCO3, NaHCO3, CaCO3, MgCO3, NaCO3, and H2CO3were analyzed along with major physico-chemical variables like pH and logpCO2. The factor analysis for these species revealed the processes and reactions taking place in the study area. The contour diagrams for all the species in both the season has revealed the origin of HCO3-and dissolution by comparing lithology and geology of the study area