Rosehip Extract-Loaded Liposomes for Potential Skin Application: Physicochemical Properties of Non- and UV-Irradiated Liposomes

In the present study, rosehip (Rosa canina L.) extract was successfully encapsulated in phospholipid liposomes using a single-step procedure named the proliposome method. Part of the obtained liposomes was subjected to UV irradiation and non-treated (native) and UV-irradiated liposomes were further characterized in terms of encapsulation efficiency, chemical composition (HPLC analysis), antioxidant capacity, particle size, PDI, zeta potential, conductivity, mobility, and antioxidant capacity. Raman spectroscopy as well as DSC analysis were applied to evaluate the influence of UV irradiation on the physicochemical properties of liposomes. The encapsulation efficiency of extract-loaded liposomes was higher than 90%; the average size was 251.5 nm; the zeta potential was -22.4 mV; and the conductivity was found to be 0.007 mS/cm. UV irradiation did not cause a change in the mentioned parameters. In addition, irradiation did not affect the antioxidant potential of the liposome-extract system. Raman spectroscopy indicated that the extract was completely covered by the lipid membrane during liposome entrapment, and the peroxidation process was minimized by the presence of rosehip extract in liposomes. These results may guide the potential application of rosehip extract-loaded liposomes in the food, pharmaceutical, or cosmetic industries, particularly when liposomal sterilization is needed

Optimization of a stand - alone renewable energy system for a small load requirement

Optimization of a stand-alone Renewable Energy (RE) system involves selecting the best RE resources and components, and sizing the system accordingly to get the most efficient and cost-effective solution. Design and optimization of an RE power system to serve the lighting in a University of the South Pacific car park was carried out using HOMER software and compared to manual calculations. Resource analysis showed that on average the site received 3.8 kWh m−2 day−1 of solar energy, with 1,387 full sun hours annually. Monthly average wind speed of 3.88 m s−1 at 10 m above ground level extrapolated to 15 m (the hub height of the wind turbine) resulted in an average wind speed of 4 m s−1, with power density of 70 Wm−2. With this wind resource, a Whisper 100 wind turbine would be in operation for approximately 50 % of the time in the year. The complementary nature of solar and wind resources showed good potential for a solar-wind hybrid system. In this study three possible systems—a PV system, a wind power system, and a hybrid power system (PV-wind)—were analyzed. It was found that a hybrid system is the best and most cost-effective option, as it is able to provide reliable power whilst minimizing the need for battery storage compared to a single RE power system. The optimum system comprised 0.270 kWp PV combined with a 900 W Whisper wind turbine with total battery storage capacity of 440 Ah at 12 V. Manual calculations yielded results similar to the HOMER simulations