4,611 research outputs found
High-fructose corn-syrup-sweetened beverage intake increases 5-hour breast milk fructose concentrations in lactating women
This study determined the effects of consuming a high-fructose corn syrup (HFCS)-sweetened beverage on breast milk fructose, glucose, and lactose concentrations in lactating women. At six weeks postpartum, lactating mothers (n = 41) were randomized to a crossover study to consume a commercially available HFCS-sweetened beverage or artificially sweetened control beverage. At each session, mothers pumped a complete breast milk expression every hour for six consecutive hours. The baseline fasting concentrations of breast milk fructose, glucose, and lactose were 5.0 ± 1.3 µg/mL, 0.6 ± 0.3 mg/mL, and 6.8 ± 1.6 g/dL, respectively. The changes over time in breast milk sugars were significant only for fructose (treatment × time, p < 0.01). Post hoc comparisons showed the HFCS-sweetened beverage vs. control beverage increased breast milk fructose at 120 min (8.8 ± 2.1 vs. 5.3 ± 1.9 µg/mL), 180 min (9.4 ± 1.9 vs. 5.2 ± 2.2 µg/mL), 240 min (7.8 ± 1.7 vs. 5.1 ± 1.9 µg/mL), and 300 min (6.9 ± 1.4 vs. 4.9 ± 1.9 µg/mL) (all p < 0.05). The mean incremental area under the curve for breast milk fructose was also different between treatments (14.7 ± 1.2 vs. −2.60 ± 1.2 µg/mL × 360 min, p < 0.01). There was no treatment × time interaction for breast milk glucose or lactose. Our data suggest that the consumption of an HFCS-sweetened beverage increased breast milk fructose concentrations, which remained elevated up to five hours post-consumption
Frontal Cognitive Function and Memory in Parkinson’s Disease: Toward a Distinction between Prospective and Declarative Memory Impairments?
Memory dysfunction is a frequent concomitant of Parkinson's disease (PD). Historically, two classes of hypotheses, focusing on different cognitive mechanisms, have been advanced to explain this memory impairment: one postulating retrieval deficits (common to several neurodegenerative disorders involving the basal ganglia), and the other postulating frontally mediated executive deficits as fundamental to memory impairment. After outlining empirical support for the retrieval deficit hypothesis, research on the more recent “frontal executive deficit hypothesis” is reviewed, and major challenges to this hypothesis are identified. It is concluded that the frontal executive deficit hypothesis cannot adequately account for all memory impairments in PD, and that a more parsimonious theoretical account might invoke a distinction between prospective and declarative memory impairments. It is suggested that there may be three subgroups of PD patients: one demonstrating prospective memory dysfunction only, one with declarative memory dysfunction only, and one with both prospective and declarative memory dysfunction. Consequently, PD might provide a useful model within which to investigate the relationship between prospective and declarative memory
Non-universal scalar-tensor theories and big bang nucleosynthesis
We investigate the constraints that can be set from big-bang nucleosynthesis
on two classes of models: extended quintessence and scalar-tensor theories of
gravity in which the equivalence principle between standard matter and dark
matter is violated. In the latter case, and for a massless dilaton with
quadratic couplings, the phase space of theories is investigated. We delineate
those theories where attraction toward general relativity occurs. It is shown
that big-bang nucleosynthesis sets more stringent constraints than those
obtained from Solar system tests.Comment: 28 pages, 20 figure
Validity of new child-specific thoracic gas volume prediction equations for air-displacement plethysmography
BACKGROUND: To determine the validity of the recently developed child-specific thoracic gas volume (TGV) prediction equations for use in air-displacement plethysmography (ADP) in diverse pediatric populations. METHODS: Three distinct populations were studied: European American and African American children living in Birmingham, Alabama and European children living in Lisbon, Portugal. Each child completed a standard ADP testing protocol, including a measured TGV according to the manufactures software criteria. Measured TGV was compared to the predicted TGV from current adult-based ADP proprietary equations and to the recently developed child-specific TGV equations of Fields et al. Similarly, percent body fat, derived using the TGV prediction equations, was compared to percent body fat derived using measured TGV. RESULTS: Predicted TGV from adult-based equations was significantly different from measured TGV in girls from each of the three ethnic groups (P < 0.05), however child-specific TGV estimates did not significantly differ from measured TGV in any of the ethnic or gender groups. Percent body fat estimates using adult-derived and child-specific TGV estimates did not differ significantly from percent body fat measures using measured TGV in any of the groups. CONCLUSION: The child-specific TGV equations developed by Fields et al. provided a modest improvement over the adult-based TGV equations in an ethnically diverse group of children
A luminosity constraint on the origin of unidentified high energy sources
The identification of point sources poses a great challenge for the high
energy community. We present a new approach to evaluate the likelihood of a set
of sources being a Galactic population based on the simple assumption that
galaxies similar to the Milky Way host comparable populations of gamma-ray
emitters. We propose a luminosity constraint on Galactic source populations
which complements existing approaches by constraining the abundance and spatial
distribution of any objects of Galactic origin, rather than focusing on the
properties of a specific candidate emitter. We use M31 as a proxy for the Milky
Way, and demonstrate this technique by applying it to the unidentified EGRET
sources. We find that it is highly improbable that the majority of the
unidentified EGRET sources are members of a Galactic halo population (e.g.,
dark matter subhalos), but that current observations do not provide any
constraints on all of these sources being Galactic objects if they reside
entirely in the disk and bulge. Applying this method to upcoming observations
by the Fermi Gamma-ray Space Telescope has the potential to exclude association
of an even larger number of unidentified sources with any Galactic source
class.Comment: 18 pages, 4 figures, to appear in JPhys
Radiative decay of a massive particle and the non-thermal process in primordial nucleosynthesis
We consider the effects on big bang nucleosynthesis (BBN) of the radiative
decay of a long-lived massive particle. If high-energy photons are emitted
after the BBN epoch ( sec), they may change the abundances of
the light elements through photodissociation processes, which may result in a
significant discrepancy between standard BBN and observation. Taking into
account recent observational and theoretical developments in this field, we
revise our previous study constraining the abundance of the
radiatively-decaying particles. In particular, on the theoretical side, it was
recently claimed that the non-thermal production of Li, which is caused by
the photodissociation of \hefour, most severely constrains the abundance of
the radiatively-decaying particle. We will see, however, it is premature to
emphasize the importance of the non-thermal production of Li because (i)
the theoretical computation of the Li abundance has large uncertainty due
to the lack of the precise understanding of the Li production cross
section, and (ii) the observational data of Li abundance has large errors.Comment: 15 pages, using REVTeX and 3 postscript figure
New Upper Limits on the Tau Neutrino Mass from Primordial Helium Considerations
In this paper we reconsider recently derived bounds on tau neutrinos,
taking into account previously unaccounted for effects. We find that, assuming
that the neutrino life-time is longer than , the constraint
rules out masses in the range
for Majorana neutrinos and
for Dirac neutrinos. Given that the present
laboratory bound is 35 MeV, our results lower the present bound to and
for Majorana and Dirac neutrinos respectively.Comment: 9 pages (2 figures available upon request), UM-AC-93-0
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