1,402 research outputs found
A "metric" complexity for weakly chaotic systems
We consider the number of Bowen sets which are necessary to cover a large
measure subset of the phase space. This introduce some complexity indicator
characterizing different kind of (weakly) chaotic dynamics. Since in many
systems its value is given by a sort of local entropy, this indicator is quite
simple to be calculated. We give some example of calculation in nontrivial
systems (interval exchanges, piecewise isometries e.g.) and a formula similar
to the Ruelle-Pesin one, relating the complexity indicator to some initial
condition sensitivity indicators playing the role of positive Lyapunov
exponents.Comment: 15 pages, no figures. Articl
Almost Fra\"iss\'e Banach spaces
Continuing with the study of Approximately ultrahomogeneous and Fra\"iss\'e
Banach spaces introduced by V. Ferenczi, J. L\'opez-Abad, B. Mbombo and S.
Todorcevic, we define formally weaker and in some aspects more natural
properties of Banach spaces which we call Almost ultrahomogeneity and the
Almost Fra\"iss\'e Property. We obtain relations between these different
homogeneity properties of a space and relate them to certain pseudometrics
on the class of finite dimensional subspaces of . We prove
that ultrapowers of an almost Fra\"iss\'e Banach space are ultrahomogeneous. We
also study two properties called finitely isometrically extensible and almost
finitely isometrically extensible, respectively, and prove that approximately
ultrahomogeneous Banach spaces are finitely isometrically extensible
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Screening for Mutations of 21-Hydroxylase Gene in Hungarian Patients with Congenital Adrenal Hyperplasia
Key Elements of the Ageing Management of the WWER-440/213 type Nuclear Power Plants
The owner’s intention of WWER-440/213 units in Central Europe is to keep the plants in operation as long as technically feasible and reasonable from business point of view. The preconditions of the long term operation and license renewal are the safety and good plant condition. The past and recent ageing management practices have to ensure the required condition and performance of the essential structures, systems and components. In the paper an overall picture of the long term operation of WWER-440/213 units is given. The review covers ageing of mechanical equipment, building structures and electrical equipment to. Key elements of the ageing management are identified and described. Basic issues of assessment of ageing of essential structures, systems and components, also the issues related to availability of design basis information and lacking environmental qualification are discussed. Reference examples typical for WWER-440/213 plants long term operation are given from Paks Nuclear Power Plant practice
Comparison of Stress-Induced Changes in Adults and Pups: Is Aldosterone the Main Adrenocortical Stress Hormone during the Perinatal Period in Rats?
Positive developmental impact of low stress-induced glucocorticoid levels in early development has been recognized for a long time, while possible involvement of mineralocorticoids in the stress response during the perinatal period has been neglected. The present study aimed at verifying the hypothesis that balance between stress-induced glucocorticoid and mineralocorticoid levels is changing during postnatal development. Hormone responses to two different stressors (insulin-induced hypoglycaemia and immune challenge induced by bacterial lipopolysaccharid) measured in 10-day-old rats were compared to those in adults. In pups corticosterone responses to both stressors were significantly lower than in adults, which corresponded well with the stress hyporesponsive period. Importantly, stress-induced elevations in aldosterone concentration were significantly higher in pups compared both to corticosterone elevations and to those in adulthood with comparable adrenocorticotropin concentrations in the two age groups. Greater importance of mineralocorticoids compared to glucocorticoids in postnatal period is further supported by changes in gene expression and protein levels of gluco- (GR) and mineralocorticoid receptors (MR) and selected enzymes measured by quantitative PCR and immunohystochemistry in the hypothalamus, hippocampus, prefrontal cortex, liver and kidney. Gene expression of 11beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2), an enzyme enabling preferential effects of aldosterone on mineralocorticoid receptors, was higher in 10-day-old pups compared to adult animals. On the contrary, the expression and protein levels of GR, MR and 11beta-HSD1 were decreased. Presented results clearly show higher stress-induced release of aldosterone in pups compared to adults and strongly suggest greater importance of mineralocorticoids compared to glucocorticoids in stress during the postnatal period
Cdc42 and Par6–PKCζ regulate the spatially localized association of Dlg1 and APC to control cell polarization
Cell polarization is essential in a wide range of biological processes such as morphogenesis, asymmetric division, and directed migration. In this study, we show that two tumor suppressor proteins, adenomatous polyposis coli (APC) and Dlg1-SAP97, are required for the polarization of migrating astrocytes. Activation of the Par6–PKCζ complex by Cdc42 at the leading edge of migrating cells promotes both the localized association of APC with microtubule plus ends and the assembly of Dlg-containing puncta in the plasma membrane. Biochemical analysis and total internal reflection fluorescence microscopy reveal that the subsequent physical interaction between APC and Dlg1 is required for polarization of the microtubule cytoskeleton
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