Infrared spectra, thermogravimetric analysis and antifungal studies of noval Cr(III), Fe(III) and Cu(II) 2-methyl-quinazolinone complexes

Some new solid complexes [CrCl3(L)3]×6H2O, [FeCl3(L)3]×6H2O and [Cu(CH3COO)2(L)3]×2H2O have been synthesized quantitatively by the interactions of 2-methyl-quinazolinone (L) with CrCl3.6H2O, FeCl3.6H2O and Cu(CH3COO)2.2H2O in a mixture of an ethanol-bidistilled water (1:1), at 60 °C. They were characterized by melting point, molar conductivity, magnetic moment, elemental analysis, infrared spectra and thermal analyses. The results supported the formation of the complexes and indicated that the ligand reacted as a monodentate ligand bound to the metal ion through the oxygen atom. The antifungal activity of the free ligand and their metal complexes were evaluated against several species, such as Fusarium solani, Rizoctonia solani, Sclortium rolfsii and Botryodiplodia and they showed a good antifungal activity to some selected fungal strain as compared with free ligand. KEY WORDS: Quinazolinone; Cr(III); Fe(III); Cu(II); Antifungal activity, Thermal analyses Bull. Chem. Soc. Ethiop. 2014, 28(1), 53-66.DOI: http://dx.doi.org/10.4314/bcse.v28i1.

Composition corporelle de poulets cou nu ou normalement emplumés: résultats dans un croisement de type chair

International audienc

The dilemma of widal test - which brand to use? a study of four different widal brands: a cross sectional comparative study

<p>Abstract</p> <p>Background</p> <p>Serodiagnosis of typhoid fever by Widal test based on demonstrating the presence of agglutinins (antibodies) in the serum of an infected patient, against the H (flagellar) and O (somatic) antigens of <it>Salmonella enterica </it>serotype Typhi has been associated with many debates. This is why the aim of this study was to: (i) Compare the diagnostic accuracy of four different commercial kits used to perform Widal test (Remel, BioSystems, Dialab and Biotec). (ii) Compare the sensitivity and specificity of both anti-O and anti-H antibodies. (iii) Compare the validity of single versus paired serum samples with a rising titer for the diagnosis of typhoid fever.</p> <p>Methods</p> <p>Duplicate serum samples were obtained from150 patients clinically diagnosed as typhoid fever patients. Moreover, single serum samples were obtained from 25 patients with febrile diseases other than typhoid fever. All samples were tested using the four different Widal brands and <it>Salmonella </it>Typhi IgM anti-LPS ELISA</p> <p>Results</p> <p><b>-</b>The results of Widal tests differed markedly using the four Widal brands in terms of sensitivity and specificity at three cut-off values of 1/80, 1/160 and 1/320. Remel brand gave the highest sensitivities and the lowest specificities and Dialab brand gave the highest specificities and the lowest sensitivities for both anti-O and anti-H antibodies at the three cut-off values.</p> <p><b>-</b>Four fold rise in the antibodies titer was not demonstrable among clinically diagnosed typhoid fever patients</p> <p>-H agglutinins were less sensitive and less specific than O agglutinins</p> <p>Conclusions</p> <p>-Widal test results showed marked discrepancies using different Widal brands. None of the serum samples of the typhoid fever patients showed four fold rise in the antibody titers. Raised O agglutinins were of slightly greater diagnostic value than raised H agglutinins.</p> <p>Significance and impact of study</p> <p>Widal test done sequentially using two brands could be of value in typhoid fever diagnosis. Single serum sample could be used for typhoid fever diagnosis relying on anti O titer.</p

Spectroscopic, thermal analyses, XRD spectra and nematicidal activity study of some new N2O2 tetradentate Schiff base metal ions complexes

ABSTRACT. A series of metal complexes [Co(HL)2(H2O)2]Cl2.5H2O (A), [Cu(HL)2](CH3COO)2.2H2O (B), [Y(HL)2]Cl3.2H2O (C), [ZrO(HL)2H2O]Cl2.H2O (D), [La(HL)2(H2O)2]Cl3.5H2O (E) and [UO2(HL)2](CH3COO)2 (F) were prepared. The structures of the compounds in solid state were detected by micro analytical, Fourier transform IR, 1H NMR, UV-Vis, mass, X-ray diffraction spectra, molar conductivity, magnetic susceptibility measurements and TG/DTG analysis. The IR spectral data point out that the ligand behaves as tridentate in nature with Cu(II), Y(III), U(VI) and bidentate with Co(II), Zr(IV) and La(III) metal ions. The conductivity values showed that the complexes found as electrolytes and the XRD models of the complexes indicated crystalline nature. The thermodynamic parameters of compounds have been detected using Coats-Redfern and Horowitz-Metzeger methods at n = 1 and n ≠ 1 and values point out more ordered activated complex formation. The nematicidal efficacy of compounds was assessed. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; KEY WORDS: Schiff base, Spectroscopic analysis, Thermal analysis, XRD, Nematicidal &nbsp; Bull. Chem. Soc. Ethiop. 2021, 35(2), 381-397. DOI: https://dx.doi.org/10.4314/bcse.v35i2.1