84 research outputs found

    Haptic Feedback for Wrist Angle Adjustment

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    Haptic feedback is envisioned to be a powerful tool in (digital) orthosis fitment procedures. In context of a larger research project on digital molding and developing a glove for orthopedic experts, we explored the use of vibrotactile feedback on the wrist for wrist angle adjustments. Five different patterns are presented on both the inside and outside of the wrist as well as crossing signals. Participants were asked to indicate whether the pattern was communicating that the wrist angle had to be increased or decreased by moving the hand up or down. The results show that the vibrotactile stimuli are being interpreted consistently by the participants, provided the patterns are presented on one side of the arm. Although the interpretations were consistent within participants, there were individual differences in the reported directions of the signals, which makes it important to take into account personal preferences and calibration when implementing haptic feedback

    Who drops out and when? Predictors of nonresponse and loss to follow-up in a longitudinal cohort study among STI clinic visitors

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    Acknowledgments The authors would like to thank Joran Slager, who assisted with the data collection and contributed to the data analyses. Furthermore, the authors thank the staff at the STI clinics of Amsterdam, Kennemerland, Hollands Noorden, Twente, especially Karin Westra, Anne de Vries, Karlijn Kampman, and Titia Heijman, who were involved in the recruitment and data collection of participants at baseline. The authors are also grateful to Marlous Ratten and Klazien Visser from Soapoli-online, who coordinated the laboratory testing of the home-based test kits at six-month follow-up, and to the staff at the STI department at the National Institute for Public Health and the Environment, especially Birgit van Benthem.Peer reviewedPublisher PD

    The Importance of Social Engagement in the Development of an HIV Cure : A Systematic Review of Stakeholder Perspectives

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    Funding Information: This research has been funded by Aidsfonds under Grant P-53001. Publisher Copyright: © 2023, The Author(s).Peer reviewedPublisher PD

    Beyond community engagement : perspectives on the meaningful involvement of people with HIV and affected communities (MIPA) in HIV cure research in The Netherlands

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    First, we express our heartfelt gratitude to all the participants who generously shared their experiences and insights, making this research possible. Your contributions are invaluable and we sincerely thank you for your time and openness. Special appreciation goes to the Dutch HIV Association of People with HIV and the HIV consultants for their collaboration and support in participant recruitment. We further thank Lissa Agema and Vaneza Paulo for their dedication to the detailed transcriptions. The PAB and CAB deserve profound acknowledgment for their efforts and significant contributions in the development and conducting of this research. Last, we acknowledge the use of the large-language model ChatGPT and Grammarly for improving clarity and conciseness.Peer reviewe

    The impact of STI test results and face-to-face consultations on subsequent behavior and psychological characteristics

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    Acknowledgments The authors would like to thank Maarten Schipper at the Biostatistics Department at the National Institute for Public Health and the Environment, who provided assistance with the statistical analyses. Furthermore, the authors are grateful to the staff at the SHC of Amsterdam, Kennemerland, Hollands Noorden, Twente (especially Karin Westra, Anne de Vries, and Karlijn Kampman) who were involved in the recruitment and data collection of participants at baseline and to Marlous Ratten and Klazien Visser from Soapoli-online, who coordinated the laboratory testing of the home-based test kits at six-month follow-up. The authors would also like to thank the staff at the STI department at the National Institute for Public Health and the Environment, especially Birgit van Benthem.Peer reviewe

    Time for change : Transitions between HIV risk levels and determinants of behavior change in men who have sex with men

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    Funding Information: This project was funded by the Netherlands Organisation for Health Research and Development ZonMw grant 522004009. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

    Study protocol of the iMPaCT project : A longitudinal cohort study assessing psychological determinants, sexual behaviour and chlamydia (re)infections in heterosexual STI clinic visitors

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    Acknowledgements We are grateful to the staff at the STI clinics of Amsterdam, Kennemerland, Hollands Noorden, Twente, who are involved in the recruitment and data collection of participants, and Marlous Ratten and Klazien Visser from Soapoli-online, who are involved in the coordination of laboratory testing of the home-based sampling kits at six-month follow-up. We also thank the staff at the STI department at the National Institute for Public Health and the Environment, especially Birgit van Benthem. Funding This project is funded by the Strategic Programme (SPR) of the National Institute for Public Health and the Environment (RIVM) (project number S/113004/01/IP). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Availability of data and materials The dataset (anonymised) generated during this study will be made available for interested parties on request.Peer reviewedPublisher PD

    Assessment of sperm quality traits in relation to fertility in boar semen

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    <p>Abstract</p> <p>Background</p> <p>Several studies have been published where sperm plasma membrane integrity correlated to fertility. In this study we describe a simple fluorometer-based assay where we monitored the fluorescence intensity of artificially membrane-ruptured spermatozoa with a fixed time staining with fluorescent DNA dyes.</p> <p>Methods</p> <p>Membrane-impermeant fluorescent dyes Hoechst 33258 (H258) and propidium iodide (PI) were used to measure the fluorescence of the nucleus in artificially membrane ruptured spermatozoa and membrane-permeant dye Hoechst 33342 (H342) was used to measure fluorescence of intact spermatozoa. The concentration of spermatozoa in insemination doses varied from 31.2 × 10<sup>6</sup>/ml to 50 × 10<sup>6</sup>/ml and the average value was 35 × 10<sup>6</sup>/ml. Each boar was represented by three consecutive ejaculates, collected at weekly intervals. Nonreturn rate within 60 days of first insemination (NR %) and litter size (total number of piglets born) of multiparous farrowings were used as fertility measures.</p> <p>Results</p> <p>Sperm fluorescence intensity of H258 and H342, but not the fluorescence intensity of PI-stained spermatozoa correlated significantly with the litter size of multiparous farrowings, values being r = - 0.68 (P < 0.01) for H258, r = - 0.69 (P < 0.01) for H342 and r = - 0.38, (P = 0.11) for PI.</p> <p>Conclusions</p> <p>The increase in fluorescence values of membrane-ruptured H258 and unruptured H342-stained spermatozoa in boar AI doses can be associated with smaller litter size after AI. This finding indicates that the fluorescence properties of the sperm nucleus could be used to select for AI doses with greater fertilizing potential.</p
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