Correlation between Osteoprotegerin Serum Levels and Arterial Stiffness Assessed by Cardio-ankle Vascular Index (CAVI) in Hypertensive Patients

Abstract The cardio-ankle vascular index (CAVI) is a newly developed clinical measurement for evaluating arterial stiffness from the origin of the aorta to the ankle. Osteoprotegerin (OPG) is widely known as a vascular calcification mediator, which have a role to affect atherogenesis. Thirty subjects participated in this research and each subject underwent a CAVI examination to assess arterial stiffness and their blood samples were collected for OPG measurement. This study is analyzed with Pearson Correlation Test. There is a positive, strong and significant correlation between osteoprotegerin serum level and arterial stiffness using Cardio-Ankle Vascular Index (CAVI) in hypertensive patients. (r = 0.730 and p <0,0001). There was a positive, strong and significant correlation between osteoprotegerin serum level and arterial stiffness using Cardio-Ankle Vascular Index (CAVI) in hypertensive patients