3,577 research outputs found

    Taguchi analysis of single layer CrN coatings on AISI 304 Stainless Steel to study its erosive corrosive wear behaviour

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    The purpose of present study was to investigate the erosive corrosive wear behavior of single layer (CrN) coatings on AISI 304 Stainless Steel samples with varying coating thickness (0-200 nm) in the range of 50 nm. The slurry jet erosive test was conducted on Slurry Jet Erosion Tester in saline slurry (3.5wt% salt) under the different working conditions with varying impact velocity (10-25 m/s), impingement angle (30°-75°) and erodent discharge (160-280 gm/min). Taguchi analysis was applied to find optimum parameters for the minimization of erosion rate of various coated and uncoated samples. The results of Taguchi experiments also indicated that among all the factors, impact velocity became least significant when samples were coated with CrN whereas it was most significant for uncoated samples. Coating thickness was the second most significant factor in the case of CrN coated samples. PVD- CrN coatings reduced the wear rate by nearly 2 times

    Erosive Corrosive Wear Performance of Single Layer CrN Coatings on AISI 304 Stainless Steel in Sea Water Centrifugal Pumps using Steady State Analysis

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    The purpose of present study was to investigate the erosive corrosive wear behavior of single layer (CrN) coatings on AISI 304 Stainless Steel samples with varying coating thickness (0-200 nm) in the range of 50 nm. The slurry jet erosive test was conducted on Slurry Jet Erosion Tester in saline slurry (3.5wt% salt) under the different working conditions with varying impact velocity (10-25 m/s), impingement angle (30°-75°) and erodent discharge (160-280 gm/min). Steady state analysis was applied to find optimum parameters for the minimization of erosion rate of various coated and uncoated samples. The finding of steady state condition tests indicated that the erosion rate increased with the increase in impact velocity and erodent discharge but decreased with the increase in coating thickness. The results also indicated that erodent discharge was the most significant factor, followed by impingement angle and impact velocity for the CrN coated samples. The SEM characterization of the eroded samples was carried out in order to analyze the topography of the eroded surface to investigate the wear mechanisms induced by slurry jet erosion test

    Lectin based glycoprotein analysis

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    Many of the biopharmaceutical therapeutics entering the market and currently in clinical trails are recombinant glycoprotein molecules, the glycan moieties of which have a significant impact on efficacy and immunogenicity. The cell culture techniques required to produce these glycoproteins often result in products that are heterogeneous with respect to glycan content. This inconsistency ultimately leads to increased production costs and restricts patient accessibility to these therapeutics. To overcome these difficulties novel analytical platforms facilitating rapid in-process monitoring and product quality control are essential. Work undertaken within the Centre for Bioanalytical Sciences (CBAS) seeks to exploit the microbial world as a source of novel biorecognition elements to produce such platforms
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