VisGenome: visualization of single and comparative genome representations

VisGenome visualizes single and comparative representations for the rat, the mouse and the human chromosomes at different levels of detail. The tool offers smooth zooming and panning which is more flexible than seen in other browsers. It presents information available in Ensembl for single chromosomes, as well as homologies (orthologue predictions including ortholog one2one, apparent ortholog one2one, ortholog many2many) for any two chromosomes from different species. The application can query supporting data from Ensembl by invoking a link in a browser

Phase-field modelling of fracture in single crystal plasticity

We propose a phase-field model for ductile fracture in a single crystal within the kinematically linear regime, by combining the theory of single crystal plasticity as formulated in Gurtin et al. (2010) and the phase-field formulation for ductile fracture proposed by Ambati et al. (2015) . The model introduces coupling between plasticity and fracture through the dependency of the so-called degradation function from a scalar global measure of the accumulated plastic strain on all slip systems. A viscous regularization is introduced both in the treatment of plasticity and in the phase-field evolution equation. Testing of the model on two examples for face centred cubic single crystals indicates that fracture is predicted to initiate and develop in the regions of the maximum accumulated plastic strain, which is in agreement with phenomenological observations. A rotation of the crystallographic unit cell is shown to affect the test results in terms of failure pattern and corresponding global and local response

Improved micro-contact resistance model that considers material deformation, electron transport and thin film characteristics

This paper reports on an improved analytic model forpredicting micro-contact resistance needed for designing microelectro-mechanical systems (MEMS) switches. The originalmodel had two primary considerations: 1) contact materialdeformation (i.e. elastic, plastic, or elastic-plastic) and 2) effectivecontact area radius. The model also assumed that individual aspotswere close together and that their interactions weredependent on each other which led to using the single effective aspotcontact area model. This single effective area model wasused to determine specific electron transport regions (i.e. ballistic,quasi-ballistic, or diffusive) by comparing the effective radius andthe mean free path of an electron. Using this model required thatmicro-switch contact materials be deposited, during devicefabrication, with processes ensuring low surface roughness values(i.e. sputtered films). Sputtered thin film electric contacts,however, do not behave like bulk materials and the effects of thinfilm contacts and spreading resistance must be considered. Theimproved micro-contact resistance model accounts for the twoprimary considerations above, as well as, using thin film,sputtered, electric contact

SXP 323 - an unusual X-ray binary system in the Small Magellanic Cloud

Spectroscopic observations taken with the VLT/UVES telescope/instrument are presented of the unusual Small Magellanic Cloud (SMC) X-ray binary system SXP 323 = AX J0051-733. This system shows a clear modulation at 0.71d in long term optical photometry which has been proposed as the binary period of this system. The high resolution optical spectra, taken at a range of phases during the 0.71d cycle, rule out this possibility. Instead it is suggested that this long-term effect is due to Non Radial Pulsations (NRP) in the Be star companion to SXP 323. In addition, the spectra show clear evidence for major changes in the (V/R) ratio of the double peaks of the Balmer lines indicative of asymmetries in the circumstellar disk. The complex structure of the interstellar lines are also discussed in the context of the SMC structure.Comment: Accepted in MNRA

Shuttle TPS thermal performance and analysis methodology

Thermal performance of the thermal protection system was approximately as predicted. The only extensive anomalies were filler bar scorching and over-predictions in the high Delta p gap heating regions of the orbiter. A technique to predict filler bar scorching has been developed that can aid in defining a solution. Improvement in high Delta p gap heating methodology is still under study. Minor anomalies were also examined for improvements in modeling techniques and prediction capabilities. These include improved definition of low Delta p gap heating, an analytical model for inner mode line convection heat transfer, better modeling of structure, and inclusion of sneak heating. The limited number of problems related to penetration items that presented themselves during orbital flight tests were resolved expeditiously, and designs were changed and proved successful within the time frame of that program