24 research outputs found
On the choice of temperature profile at solving the heat conduction equation in spherical coordinates by the method of thermal balance integral
Solutions of the heat conduction equation for a sphere and an area limited from within by a spherical cavity have been obtained by means of the integrated method. The influence of the choice of the temperature profile on efficiency of the approached analytical solution is shown. The variant of solution specification in transitive area is offered
Effect of Laser Modification on Composite Films with Nanodispersed SiO2
ABSTRACT: Introduction. This research is aimed at studying the effect of laser modification on composite films obtained on the basis of polyimide track (nuclear) membranes and filled with nanodispersed SiO2; to change their optical and structural properties. Materials and research methods. Polyimide track (nuclear) membranes were used as a polymer matrix. Track diameter is 200 nm, membrane thickness is 25 ΞΌm. The tracks were filled with nanosized SiO2 by hydrolysis of tetraethoxysilane in the presence of track membranes. For composite film surface modification, we used ytterbium pulsed fiber laser Minimarker 2-20 A4 PA. We studied the change in the surface microscopy of composite films, their optical density, IR-Fourier spectra and surface wettability depending on laser treatment. Results and discussion. The authors have found the possibility of creating a composite film based on a polyimide track (nuclear) membrane and nanodispersed SiO2 by hydrolysis of tetraethoxysilane in the presence of a membrane. It is shown with the energy dispersive analysis method that silicon oxide has completely filled the pore volume of the track membrane. Laser
modification of the composite material surface (composite film) leads to an increase in the contact angle of wetting from ΞΈ = 66.75 Β± 1.55Β° to ΞΈ = 101.52 Β± 3.03Β°. Thus, the material acquires hydrophobic properties. Also, the laser films modification has a positive effect on the transmittance of the films, namely, this coefficient increases. The greatest change is observed in the infrared region of Π΅mitted spectrum, the average increase in transmission is +70.48%. Conclusion. The obtained results of the study are of great importance for understanding the mechanisms of creating composite films with improved optical properties, which can later be used to create
composite films with desired optical properties for various application
Π ΠΎΠ»Ρ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΎΠΌΠΎΡΠΎΡΠΎΠ² Π³Π΅ΡΠΏΠ΅ΡΠ²ΠΈΡΡΡΠΎΠ² Π² ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΏΠ°ΡΠΎΠ³Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π° Π½Π° ΠΏΡΠΈΠΌΠ΅ΡΠ΅ Π±ΠΎΠ»Π΅Π·Π½ΠΈ ΠΠ°ΡΠ΅ΠΊΠ°
Marekβs disease virus is ubiquitous and can harm not only poultry, but also be oncogenic for humans. VBM and malignant tumors induced by them are a convenient and accessible natural model for studying herpesvirus-associated carcinogenesis. To date, according to our observations, there are additional risks of human infection with the Marekβs disease virus - the disease began to appear in broiler chickens 30 days and older, i.e. contact with poultry meat carries a risk of infection. In addition, COVID-19 disease may be accompanied by folic acid deficiency, i.e. a violation of the folate cycle in humans, which increases the risk of manifestation of diseases associated with DNA viruses, since a violation of the folate cycle can reduce the activity of DNA methylation, incl. viral DNA. Methylation is carried out enzymatically in the first minutes after DNA replication, i.e. postreplicatively. Since the DNA nucleotide sequence does not change, methylation is essentially an epigenetic event. We have studied the relationship between the methylation of promoters of the Marekβs disease virus and the copy number of the virus. The assessment of the presence or absence of methylation, as well as partial methylation, was carried out on the basis of identifying the difference between the threshold cycles dC(t). The presence of unmethylated sites included in the studied promoter sequence was detected on the basis of the ability of methylsensitive restrictases AciI and GlaI. A correlation was found between the concentration of genomic DNA of the Marekβs disease virus serotype 1 strain CVI 988 in cell culture and the presence of demethylated CpG islands in the composition of promoters located at position 9413-9865 bp. and 127943 - 128193 b.p. genomic DNA of the virus. The data obtained make it possible to explain the mechanism of the increase in the pathogenicity of herpesvirus infections under conditions of a decrease in the activity of viral DNA methylation in the body.ΠΠΈΡΡΡ Π±ΠΎΠ»Π΅Π·Π½ΠΈ ΠΠ°ΡΠ΅ΠΊΠ° (ΠΠΠ) ΠΈΠΌΠ΅Π΅Ρ ΠΏΠΎΠ²ΡΠ΅ΠΌΠ΅ΡΡΠ½ΠΎΠ΅ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΠ΅ ΠΈ ΠΌΠΎΠΆΠ΅Ρ Π½Π΅ ΡΠΎΠ»ΡΠΊΠΎ Π½Π°Π½ΠΎΡΠΈΡΡ Π²ΡΠ΅Π΄ Π΄ΠΎΠΌΠ°ΡΠ½Π΅ΠΉ ΠΏΡΠΈΡΠ΅, Π½ΠΎ ΠΈ ΠΎΠ±Π»Π°Π΄Π°ΡΡ ΠΎΠ½ΠΊΠΎΠ³Π΅Π½Π½ΠΎΡΡΡΡ Π΄Π»Ρ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°. ΠΠΠ ΠΈ ΠΈΠ½Π΄ΡΡΠΈΡΡΠ΅ΠΌΡΠ΅ ΠΈΠΌΠΈ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠ΅ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΡΠ²Π»ΡΡΡΡΡ ΡΠ΄ΠΎΠ±Π½ΠΎΠΉ ΠΈ Π΄ΠΎΡΡΡΠΏΠ½ΠΎΠΉ Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΌΠΎΠ΄Π΅Π»ΡΡ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ ΠΊΠ°Π½ΡΠ΅ΡΠΎΠ³Π΅Π½Π΅Π·Π°, Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ Ρ Π³Π΅ΡΠΏΠ΅ΡΠ²ΠΈΡΡΡΠ°ΠΌΠΈ. ΠΠ° ΡΠ΅Π³ΠΎΠ΄Π½ΡΡΠ½ΠΈΠΉ Π΄Π΅Π½Ρ, ΠΏΠΎ Π½Π°ΡΠΈΠΌ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΡΠΌ, ΠΏΠΎΡΠ²ΠΈΠ»ΠΈΡΡ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ ΡΠΈΡΠΊΠΈ Π·Π°ΡΠ°ΠΆΠ΅Π½ΠΈΡ Π»ΡΠ΄Π΅ΠΉ Π²ΠΈΡΡΡΠΎΠΌ Π±ΠΎΠ»Π΅Π·Π½ΠΈ ΠΠ°ΡΠ΅ΠΊΠ° β Π±ΠΎΠ»Π΅Π·Π½Ρ Π½Π°ΡΠ°Π»Π° ΠΏΠΎΡΠ²Π»ΡΡΡΡΡ Ρ ΡΡΠΏΠ»ΡΡ-Π±ΡΠΎΠΉΠ»Π΅ΡΠΎΠ² 30 Π΄Π½Π΅ΠΉ ΠΈ ΡΡΠ°ΡΡΠ΅, Ρ.Π΅. ΠΊΠΎΠ½ΡΠ°ΠΊΡ Ρ ΠΌΡΡΠΎΠΌ ΠΏΡΠΈΡΡ Π½Π΅ΡΠ΅Ρ ΡΠΈΡΠΊ Π·Π°ΡΠ°ΠΆΠ΅Π½ΠΈΡ. ΠΠΎΠΌΠΈΠΌΠΎ ΡΡΠΎΠ³ΠΎ, Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠ΅ COVID-19 ΠΌΠΎΠΆΠ΅Ρ ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π°ΡΡΡΡ Π΄Π΅ΡΠΈΡΠΈΡΠΎΠΌ ΡΠΎΠ»ΠΈΠ΅Π²ΠΎΠΉ ΠΊΠΈΡΠ»ΠΎΡΡ, Ρ.Π΅. Π½Π°ΡΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΡΠΎΠ»Π°ΡΠ½ΠΎΠ³ΠΎ ΡΠΈΠΊΠ»Π° Ρ Π»ΡΠ΄Π΅ΠΉ, ΡΡΠΎ ΠΏΠΎΠ²ΡΡΠ°Π΅Ρ ΡΠΈΡΠΊ ΠΌΠ°Π½ΠΈΡΠ΅ΡΡΠ°ΡΠΈΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ, ΡΠ²ΡΠ·Π°Π½Π½ΡΡ
Ρ ΠΠΠ-Π²ΠΈΡΡΡΠ°ΠΌΠΈ, ΡΠ°ΠΊ ΠΊΠ°ΠΊ Π½Π°ΡΡΡΠ΅Π½ΠΈΠ΅ ΡΠΎΠ»Π°ΡΠ½ΠΎΠ³ΠΎ ΡΠΈΠΊΠ»Π° ΡΠΏΠΎΡΠΎΠ±Π½ΠΎ ΡΠ½ΠΈΠ·ΠΈΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΠΠ, Π² Ρ.Ρ. Π²ΠΈΡΡΡΠ½ΠΎΠΉ ΠΠΠ. ΠΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΎΡΡΡΠ΅ΡΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ΅ΡΠΌΠ΅Π½ΡΠ°ΡΠΈΠ²Π½ΠΎ Π² ΠΏΠ΅ΡΠ²ΡΠ΅ ΠΌΠΈΠ½ΡΡΡ ΠΏΠΎΡΠ»Π΅ ΡΠ΅ΠΏΠ»ΠΈΠΊΠ°ΡΠΈΠΈ ΠΠΠ, Ρ.Π΅. ΠΏΠΎΡΡΡΠ΅ΠΏΠ»ΠΈΠΊΠ°ΡΠΈΠ²Π½ΠΎ. ΠΠΎΡΠΊΠΎΠ»ΡΠΊΡ Π½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ΄Π½Π°Ρ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡ ΠΠΠ ΠΏΡΠΈ ΡΡΠΎΠΌ Π½Π΅ ΠΌΠ΅Π½ΡΠ΅ΡΡΡ, ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΠΎ ΡΡΡΠΈ ΡΠ²ΠΎΠ΅ΠΉ β ΡΠΎΠ±ΡΡΠΈΠ΅ ΡΠΏΠΈΠ³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ΅. ΠΠ°ΠΌΠΈ Π±ΡΠ»Π° ΠΈΠ·ΡΡΠ΅Π½Π° Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΡ ΠΌΠ΅ΠΆΠ΄Ρ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΏΡΠΎΠΌΠΎΡΠΎΡΠΎΠ² Π²ΠΈΡΡΡΠ° Π±ΠΎΠ»Π΅Π·Π½ΠΈ ΠΠ°ΡΠ΅ΠΊΠ° ΠΈ ΠΊΠΎΠΏΠΈΠΉΠ½ΠΎΡΡΡΡ Π²ΠΈΡΡΡΠ°. ΠΡΠ΅Π½ΠΊΠ° Π½Π°Π»ΠΈΡΠΈΡ ΠΈΠ»ΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΡ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ, ΡΠ°ΠΊ ΠΆΠ΅ ΠΊΠ°ΠΊ ΠΈ ΡΠ°ΡΡΠΈΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ, ΠΎΡΡΡΠ΅ΡΡΠ²Π»ΡΠ»Π°ΡΡ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ ΡΠ°Π·Π½ΠΈΡΡ ΠΌΠ΅ΠΆΠ΄Ρ ΠΏΠΎΡΠΎΠ³ΠΎΠ²ΡΠΌΠΈ ΡΠΈΠΊΠ»Π°ΠΌΠΈ dC(t). ΠΠ°Π»ΠΈΡΠΈΠ΅ Π½Π΅ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΡΠ°ΠΉΡΠΎΠ², Π²Ρ
ΠΎΠ΄ΡΡΠΈΡ
Π² ΡΠΎΡΡΠ°Π² ΠΈΠ·ΡΡΠ°Π΅ΠΌΠΎΠΉ ΠΏΡΠΎΠΌΠΎΡΠΎΡΠ½ΠΎΠΉ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ, Π²ΡΡΠ²Π»ΡΠ»ΠΎΡΡ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ ΠΌΠ΅ΡΠΈΠ»ΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΡΠ΅ΡΡΡΠΈΠΊΡΠ°Π· AciI ΠΈ GlaI. ΠΡΠ»Π° ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½Π° ΠΊΠΎΡΡΠ΅Π»ΡΡΠΈΠΎΠ½Π½Π°Ρ Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΡ ΠΌΠ΅ΠΆΠ΄Ρ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠ΅ΠΉ Π³Π΅Π½ΠΎΠΌΠ½ΠΎΠΉ ΠΠΠ Π²ΠΈΡΡΡΠ° Π±ΠΎΠ»Π΅Π·Π½ΠΈ ΠΠ°ΡΠ΅ΠΊΠ° 1-Π³ΠΎ ΡΠ΅ΡΠΎΡΠΈΠΏΠ° ΡΡΠ°ΠΌΠΌΠ° CVI988 Π² ΠΊΡΠ»ΡΡΡΡΠ΅ ΠΊΠ»Π΅ΡΠΎΠΊ ΠΈ Π½Π°Π»ΠΈΡΠΈΠ΅ΠΌ Π΄Π΅ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
CpG-ΠΎΡΡΡΠΎΠ²ΠΊΠΎΠ² Π² ΡΠΎΡΡΠ°Π²Π΅ ΠΏΡΠΎΠΌΠΎΡΠΎΡΠΎΠ², Π»ΠΎΠΊΠ°Π»ΠΈΠ·ΡΡΡΠΈΡ
ΡΡ Π² ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠΈ 9413β9865 ΠΈ 127943β128193 ΠΏ.Π½. Π³Π΅Π½ΠΎΠΌΠ½ΠΎΠΉ ΠΠΠ Π²ΠΈΡΡΡΠ°. ΠΠΎΠ»ΡΡΠ΅Π½Π½ΡΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡ ΠΎΠ±ΡΡΡΠ½ΠΈΡΡ ΠΌΠ΅Ρ
Π°Π½ΠΈΠ·ΠΌ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΡ ΠΏΠ°ΡΠΎΠ³Π΅Π½Π½ΠΎΡΡΠΈ Π³Π΅ΡΠΏΠ΅ΡΠ²ΠΈΡΡΡΠ½ΡΡ
ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΉ Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π²ΠΈΡΡΡΠ½ΠΎΠΉ ΠΠΠ Π² ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠ΅
A Conceptual Modelling Approach to Visualising Linked Data
Increasing numbers of Linked Open Datasets are being published, and many possible data visualisations may be appropriate for a user's given exploration or analysis task over a dataset. Users may therefore find it difficult to identify visualisations that meet their data exploration or analyses needs. We propose an approach that creates conceptual models of groups of commonly used data visualisations, which can be used to analyse the data and users' queries so as to automatically generate recommendations of possible visualisations. To our knowledge, this is the first work to propose a conceptual modelling approach to recommending visualisations for Linked Data
The state of dairy cattle breeding and clustering of municipal entities of the Krasnoyarsk Territory by the level of industry development
Effect of electrochemical modification of titanium hydride fraction on oxygen content in surface and deep layers
The paper presents a study of the microstructure and oxygen concentration in the surface and deep layers of fractions of unmodified titanium hydride and titanium hydride modified by electrodeposited layers of Ti and Cu at temperatures of 300 Β°Cβ900 Β°C. The composition of the oxide layer and the concentration of titanium and oxygen atoms are estimated. It is shown that an increase in the thickness and compaction of the oxide layer with increasing temperature prevents the penetration of oxygen into the deep layers of the unmodified fraction of titanium hydride. Modification of titanium hydride by electrochemical deposition of metallic titanium at a temperature of 700 Β°C reduces the oxygen concentration in titanium hydride at a layer depth of 50 ΞΌ m from 35 wt% to 12.5 wt%. Electrodeposition of coatings based on titanium and copper at 700 Β°C reduces the oxygen concentration to 9.2 wt%, which may be due to the protective mechanism of the formed copper titanate layer. At 900 Β°C, in the modification layer based on titanium and copper, due to the eutectoid transformation of the Ξ² -phase of titanium, the process of contact melting occurs and a multiphase zone is formed. The oxygen concentration at a layer depth of 50 ΞΌ m is no more than 12.4 wt%