21 research outputs found

    Accidental Discovery of Pregnancy-associated Septic Sacroilitis on Ultrasound

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    Pain in the sacroiliac joint and lower back is common during pregnancy and postpartum periods. However, pregnancy related septic sacroilitis is very rare. A 37-year-old pregnant woman had a sudden severe lower back pain two days in advance of the delivery. However, she delivered a healthy baby under cesarean section in good condition. Laboratory tests revealed elevated erythrocyte sedimentation and C-reactive protein, but her initial magnetic resonance imaging of lumbar spine and abdominal pelvis computed tomography were normal. Therefore, she was considered having a general acute back pain that many postpartum patients can have. Conservative treatment was received until she was referred to pain clinic. While we were planning pain management under ultrasound guided, we encounterd mass-like lesion on her left sacroiliac joint accidentally. Sacroiliac MRI was taken immediately and It revealed septic sacroilitis. Pregnant with high ESR, CPR with severe localized sacroiliac joint pain should be suspected of pregnancy related septic sacroilitis.ope

    ์งˆ์‚ฐ ํ‘œ๋ฉด์ฒ˜๋ฆฌ์— ์˜ํ•ด ํ˜•์„ฑํ•œ ์ €๋‹ˆ์ผˆ ๋“€ํ”Œ๋ ‰์Šค ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ๋ถ€๋™ํƒœ๋ง‰๊ณผ ๊ทธ ๋‚ด์‹ํŠน์„ฑ

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    ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์€ ๋ถ€์‹์— ๊ฐ•ํ•˜๊ณ  ๋‚ด๋งˆ๋ชจ์„ฑ ๋ฐ ๋‚ด์‚ฐํ™”์„ฑ ๋“ฑ์ด ์šฐ์ˆ˜ํ•˜์—ฌ ๋‹ค์–‘ํ•œ ์‚ฐ์—…๋ถ„์•ผ์—์„œ ์‚ฌ์šฉ๋˜์–ด์ง€๊ณ  ์žˆ๋‹ค. ํŠนํžˆ ์˜ค์Šคํ…Œ๋‚˜์ดํŠธ์™€ ํŽ˜๋ผ์ดํŠธ์ƒ์ด ํ˜ผํ•ฉ๋œ ๋“€ํ”Œ๋ ‰์Šค ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์€ ์šฐ์ˆ˜ํ•œ ๋‚ด์‹์„ฑ, ๋†’์€ ๊ฐ•๋„, ์–‘ํ˜ธํ•œ ๊ฐ€๊ณต์„ฑ, ์•ˆ์ •์  ๊ฐ€๊ฒฉ๋ณ€๋™์˜ ํŠน์ง•์„ ๊ฐ€์ง„ ์ฒ ๊ฐ•์žฌ๋กœ์จ ๊ทธ ์‚ฌ์šฉ๋Ÿ‰์ด ๊พธ์ค€ํžˆ ์ฆ๊ฐ€ํ•˜๊ณ  ์žˆ๋‹ค. ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ์—ฌ๋Ÿฌ ํ•ฉ๊ธˆ ์›์†Œ ์ค‘ ๋‚ด์‹์„ฑ๊ณผ ์ง์ ‘์ ์ธ ์—ญํ• ์„ ํ•˜๋Š” ํฌ๋กฌ ์ด์™ธ์—, ๋‹ˆ์ผˆ์€ ํŽ˜๋ผ์ดํŠธ์˜ ์ƒ๋ณ€ํƒœ์— ํฐ ์˜ํ–ฅ์„ ์ฃผ๋Š” ์›์†Œ์ด๋‹ค. ๋‹ˆ์ผˆ์€ ์˜ค์Šคํ…Œ๋‚˜์ดํŠธ๊ณ„ ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ๊ฐ€๊ฒฉ ๋ณ€๋™์„ฑ์— ํฐ ์˜ํ–ฅ์„ ๋ฏธ์น˜๊ธฐ ๋•Œ๋ฌธ์— ์ด๋ฅผ ๋Œ€์ฒดํ•˜๋ ค๋Š” ์—ฐ๊ตฌ๊ฐ€ ์ง„ํ–‰๋˜์—ˆ๊ณ , ๊ทธ ๊ฒฐ๊ณผ, ๋‹ˆ์ผˆ์˜ ํ•จ๋Ÿ‰์€ ์ค„์ด๊ณ  ๋ง๊ฐ„๊ณผ ์งˆ์†Œ ๋“ฑ์„ ์ฒจ๊ฐ€ํ•œ ์ €๋‹ˆ์ผˆ ๋“€ํ”Œ๋ ‰์Šค ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•(STS 329 Formability Lean Duplex, FLD)์ด ๋“ฑ์žฅํ•˜์˜€๋‹ค. ํ•˜์ง€๋งŒ STS 329 FLD ๋‚ด ๋‹ˆ์ผˆ์˜ ๊ฐ์†Œ๋กœ ์ธํ•˜์—ฌ ๋‚ด์‹์„ฑ ๋“ฑ ๋ณด์™„ํ•ด์•ผํ•  ๋ฌธ์ œ๊ฐ€ ๋ฐœ์ƒํ•˜๊ณ  ์žˆ๋‹ค. ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ๋‚ด์‹์„ฑ์„ ์ฆ๋Œ€์‹œํ‚ค๋Š” ๋‹ค์–‘ํ•œ ๋ฐฉ์•ˆ์ด ์กด์žฌํ•˜๋ฉฐ ๊ทธ ์ค‘ ํ‘œ๋ฉด์ฒ˜๋ฆฌ๋ฒ•์€ ๊ณต์ •์ด ๋‹จ์ˆœํ•˜๊ณ  ๊ฐ€๊ฒฉ ๊ฒฝ์Ÿ๋ ฅ์ด ์šฐ์ˆ˜ํ•œ ์žฅ์ ์ด ์žˆ๋‹ค. ํ‘œ๋ฉด์ฒ˜๋ฆฌ๋ฒ• ์ค‘ ํ™”ํ•™์  ๋ถ€๋™ํƒœํ™”(Chemical passivation)๋Š” ๊ตฌ์—ฐ์‚ฐ, ์งˆ์‚ฐ ๋“ฑ์„ ์ด์šฉํ•˜์—ฌ ๋ถ€๋™ํƒœ๋ง‰์—์„œ ๋ถ€๋™ํƒœ๋ง‰์˜ ํฌ๋กฌ์‚ฐํ™”๋ฌผ์˜ ์น˜๋ฐ€๋„์˜ ์ฆ๊ฐ€, ๊ฐœ์žฌ๋ฌผ(Inclusion)์˜ ์ œ๊ฑฐ ๋“ฑ์— ์˜ํ•˜์—ฌ ๋‚ด์‹์„ฑ์„ ์ฆ๋Œ€์‹œํ‚ค๋Š” ๋ฐฉ๋ฒ•์ด๋‹ค. ์ด๋Ÿฌํ•œ ์ฒ˜๋ฆฌ๋ฒ• ์ค‘ ์งˆ์‚ฐ ์šฉ์•ก์— ์‚ฐํ™”์ œ๋ฅผ ์ฒจ๊ฐ€ํ•  ๊ฒฝ์šฐ ์‚ฐํ™”ํ™˜์›์ „์œ„์˜ ์ƒ์Šน์œผ๋กœ ์ธํ•˜์—ฌ ์ˆ˜์‚ฐํ™”ํฌ๋กฌ(Cr2(OH)3)์ด ์‚ฐ์„ฑ ํ™˜๊ฒฝ์—์„œ ๋‚ด์‹์„ฑ์ด ์šฐ์ˆ˜ํ•œ ์‚ฐํ™”ํฌ๋กฌ (Cr2O3)์œผ๋กœ ๊ณ ์ฒด์ƒ ๋ณ€ํ™”ํ•˜์—ฌ ๋ถ€๋™ํƒœ๋ง‰์˜ ๋‚ด์‹์„ฑ์ด ๋”์šฑ ์ฆ๊ฐ€ํ•œ๋‹ค. ๊ธฐ์กด์—๋Š” ์‚ฐํ™”์ œ๋กœ ์ค‘ํฌ๋กฌ์‚ฐ๋‚˜ํŠธ๋ฅจ์ด ์ฃผ๋กœ ์‚ฌ์šฉ๋˜์—ˆ์œผ๋‚˜, ์ค‘ํฌ๋กฌ์‚ฐ๋‚˜ํŠธ๋ฅจ์˜ ํ™˜๊ฒฝ์  ๋ฌธ์ œ๋กœ ์ธํ•œ ์ œ์ œ๋กœ ์ƒˆ๋กœ์šด ๋Œ€์ฒด์ œ์˜ ๊ฐœ๋ฐœ์ด ์‹œ๊ธ‰ํ•œ ์ƒํ™ฉ์ด๋‹ค. ๋ณธ ๋…ผ๋ฌธ์—์„œ๋Š” ์งˆ์‚ฐ ํ™˜๊ฒฝ์—์„œ ํ™”ํ•™์  ๋ถ€๋™ํƒœํ™” ์ฒ˜๋ฆฌ๋ฒ•์— ์˜ํ•ด STS 329 FLD์˜ ๋ถ€๋™ํƒœ๋ง‰์˜ ํ˜•์„ฑ์— ๋Œ€ํ•˜์—ฌ ์—ฐ๊ตฌํ•˜์˜€๋‹ค. STS 304์™€ STS 329 FLD์˜ ๊ธ€๋กœ์šฐ ๋ฐฉ์ „ ๋ถ„๊ด‘ ๋ถ„์„๋ฒ•(Glow discharge optical emission spectrometer)์„ ์ด์šฉํ•˜์—ฌ ๊นŠ์ด๋ณ„ ์›์†Œ๋ถ„ํฌ์˜ ํŠน์„ฑ์ฐจ์ด ๋ฐ ํ•ฉ๊ธˆ์›์†Œ์˜ ์ƒ๋Œ€๋น„์œจ๊ณผ STS 304์™€ STS 329 FLD์˜ ์–‘๊ทน๋ถ„๊ทน ๊ณก์„ (Anodic polarization curve)์„ ํŠน์„ฑ์„ ๋น„๊ตํ•˜์—ฌ STS 329 FLD์˜ STS 304 ๋Œ€๋น„ ๋‚ด์‹ํŠน์„ฑ์„ ๊ณ ์ฐฐํ•˜์˜€๋‹ค. ๋˜ํ•œ ์‚ฐํ™”์ œ๋กœ์„œ Na2MoO4์˜ ์ฒจ๊ฐ€์— ์˜ํ•ด ํ˜•์„ฑ๋˜๋Š” ๋ถ€๋™ํƒœ๋ง‰์˜ ํ˜•์„ฑ ๋ฉ”์นด๋‹ˆ์ฆ˜์— ๋Œ€ํ•˜์—ฌ ๊ณ ์ฐฐํ•˜์˜€๋‹ค. ์‹คํ—˜ ๊ฒฐ๊ณผ, ๋ชฐ๋ฆฌ๋ธŒ๋ด์‚ฐ๋‚˜ํŠธ๋ฅจ์„ ์งˆ์‚ฐ ์šฉ์•ก์— ์ฒจ๊ฐ€ํ•จ์œผ๋กœ์จ ๋ชฐํฌ๋กœ์ง€, ๋ถ€๋™ํƒœ๋ง‰์˜ ๊นŠ์ด๋ณ„ ์›์†Œ ๋ถ„ํฌ ํŠน์„ฑ, ๋‚ด์‹ ํŠน์„ฑ์— ์˜ํ–ฅ์„ ๋ฏธ์ณค๋‹ค. ๋ชฐํฌ๋กœ์ง€์—์„œ ๋ชฐ๋ฆฌ๋ธŒ๋ด์‚ฐ๋‚˜ํŠธ๋ฅจ์ด ์ฒจ๊ฐ€๋จ์— ๋”ฐ๋ผ ํ‘œ๋ฉด์˜ ๊ฐœ์žฌ๋ฌผ์ด ๊ฐ์†Œํ•˜์˜€๋‹ค. ๊ทธ๋กœ ์ธํ•˜์—ฌ ์–‘๊ทน๋ถ„๊ทน ๊ณก์„ ์—์„œ ๊ณต์‹์ „์œ„๊ฐ€ ์ฆ๊ฐ€ํ•˜์˜€๊ณ , ์กฐ๋„ ์ธก์ • ๊ฒฐ๊ณผ์—์„œ ํ‘œ๋ฉด์˜ ๊ฑฐ์น ๊ธฐ๊ฐ€ ์ฆ๊ฐ€ํ•˜์˜€๋‹ค. ๋ถ€๋™ํƒœ๋ง‰์˜ ๊นŠ์ด๋ณ„ ์›์†Œ ๋ถ„ํฌ๋Š” ๋ชฐ๋ฆฌ๋ธŒ๋ด์‚ฐ๋‚˜ํŠธ๋ฅจ์ด ์ฒจ๊ฐ€๋จ์— ๋”ฐ๋ผ ๋ถ€๋™ํƒœ๋ง‰์˜ ํ‘œ๋ฉด์ธต์—์„œ ์ฒ ์˜ ํ•จ๋Ÿ‰์€ ๊ฐ์†Œํ•˜์˜€๊ณ , ํฌ๋กฌ์€ ์ฆ๊ฐ€ํ•˜์˜€๋‹ค. ๊ทธ๋กœ์ธํ•ด ์–‘๊ทน๋ถ„๊ทน ๊ณก์„ ์—์„œ ๋ถ€์‹์ „๋ฅ˜๊ฐ€ ๊ฐ์†Œํ•˜์˜€๋‹ค. ์ „๊ธฐํ™”ํ•™์  ์ž„ํ”ผ๋˜์Šค ์ธก์ •๊ฒฐ๊ณผ์—์„œ ๋ชฐ๋ฆฌ๋ธŒ๋ด์‚ฐ๋‚˜ํŠธ๋ฅจ์„ ์ฒจ๊ฐ€ํ•œ ๊ฒฝ์šฐ์— ๋ถ€๋™ํƒœ๋ง‰์˜ ์ปคํŒจ์‹œํ„ด์Šค๊ฐ€ ์ฆ๊ฐ€ํ•˜์˜€๋‹ค. ์ด๋Š” ๋ถ€๋™ํƒœ๋ง‰ ๋‘๊ป˜์˜ ๊ฐ์†Œ์— ์˜ํ•œ ์ฆ๊ฐ€๋ฟ๋งŒ ์•„๋‹ˆ๋ผ ๋ถ€๋™ํƒœ๋ง‰์˜ ์ตœ์™ธ๊ณฝ์— ํก์ฐฉ๋œ ๋ชฐ๋ฆฌ๋ธŒ๋ด์ด ์ด์˜จ์ƒํƒœ๋กœ ์กด์žฌํ•จ์œผ๋กœ์จ ์ตœ์™ธ๊ณฝ ํ‘œ๋ฉด์€ ์–‘์ด์˜จ ์„ ํƒ์ธต, ๋‚ด์ธต์€ ์Œ์ด์˜จ ์„ ํƒ์ธต ํ˜•์„ฑ์œผ๋กœ ์ธํ•˜์—ฌ ์ปคํŒจ์‹œํ„ด์Šค๊ฐ€ ์ฆ๊ฐ€ํ•œ ๊ฒƒ์œผ๋กœ ์‚ฌ๋ฃŒ๋œ๋‹ค. ๋ถ€๋™ํƒœ๋ง‰์ด ๋ชฐ๋ฆฌ๋ธŒ๋ด์˜ ํก์ฐฉ์— ์˜ํ•ด์„œ ์ „๊ธฐ์  ์ด์ค‘์ธต์„ ํ˜•์„ฑํ•จ์— ๋”ฐ๋ผ ์–‘๊ทน๋ถ„๊ทน ๊ณก์„ ์—์„œ ๋ถ€์‹์ „์œ„๊ฐ€ ์ƒ์Šนํ•˜์˜€๋‹ค. ๋˜ํ•œ ๋ชฐ๋ฆฌ๋ธŒ๋ด์‚ฐ๋‚˜ํŠธ๋ฅจ์ด ์ฒจ๊ฐ€๋œ ์งˆ์‚ฐ์šฉ์•ก์—์„œ ํ‘œ๋ฉด ์ฒ˜๋ฆฌ์‹œ๊ฐ„์ด ๊ธธ์–ด์ง์— ๋”ฐ๋ผ ํฌ๋กฌ์˜ ํ•จ๋Ÿ‰์ด ์ฆ๊ฐ€ํ•˜์—ฌ ๋ถ€์‹์ „๋ฅ˜๊ฐ€ ๊ฐ์†Œํ•˜์˜€๊ณ  ํ‘œ๋ฉด์˜ ๊ฐœ์žฌ๋ฌผ์˜ ๊ฐ์†Œ๋กœ ์ธํ•ด ๊ณต์‹์ „์œ„๊ฐ€ ์ฆ๊ฐ€ํ•˜์˜€๋‹ค. ๋ถ€๋™ํƒœ๋ง‰์˜ ๋‘๊ป˜๋Š” ์‹œ๊ฐ„์ด ์ฆ๊ฐ€ํ•จ์— ๋”ฐ๋ผ ๊ฐ์†Œํ•˜์˜€๋‹ค. ์ตœ์™ธ๊ณฝ ํ‘œ๋ฉด์˜ ๋ชฐ๋ฆฌ๋ธŒ๋ด์˜ ํ•จ๋Ÿ‰์€ 60๋ถ„์—์„œ ๊ฐ์†Œํ•˜์˜€์œผ๋ฉฐ, ๊ทธ ์˜ํ–ฅ์œผ๋กœ ์ „๊ธฐํ™”ํ•™์  ์ž„ํ”ผ๋˜์Šค์˜ ์ปคํŒจ์‹œํ„ด์Šค๊ฐ€ ๊ฐ์†Œํ•˜์˜€๋‹ค. ์ด๋Ÿฌํ•œ ๊ฒฐ๊ณผ๋“ค์„ ํ† ๋Œ€๋กœ ๋ชฐ๋ฆฌ๋ธŒ๋ด์‚ฐ๋‚˜ํŠธ๋ฅจ์ด ์ค‘ํฌ๋กฌ์‚ฐ๋‚˜ํŠธ๋ฅจ์˜ ๋Œ€์ฒด์ œ๋กœ์„œ ๊ฐ€๋Šฅ์„ฑ์„ ํ™•์ธํ•˜์˜€๊ณ , STS 329 FLD์˜ ๋‚ด์‹์„ฑ ํ–ฅ์ƒ์— ๋Œ€ํ•œ ๊ธฐ์ดˆ์ ์ธ ์ง€์นจ์„ ์ œ์‹œํ•  ์ˆ˜ ์žˆ์—ˆ๋‹ค.|Over several decades, stainless steels are used in various industrial fields, due to corrosion, abrasion and oxidation resistances. Duplex stainless steels which are mixed with austenite and ferrite phases are steadily increasing in their use as steels with good corrosion resistance, high strength, good formability and stable price fluctuation. In addition to chromium, which plays a direct role in the corrosion resistance of various alloying elements in stainless steel, nickel is a factor that greatly affects the phase transformation of ferrite to austenite. Nickel has had a significant impact on the price volatility of austenitic stainless steels, and studies have been undertaken to replace them. As a result, stainless steel(STS 329 Formability Lean Duplex, FLD) with nickel reduced and manganese and nitrogen was added was developed. However, there is a problem that corrosion resistance is reduced due to reduction of nickel. There are various ways to increase the corrosion resistance of stainless steel, among which surface treatment has advantages of simple process and excellent price competitiveness. Chemical passivation among the surface treatment methods is a method of increasing the corrosion resistance by increasing the density of the chromium oxide of passive films and removing the inclusions in passive films by using citric acid or nitric acid. When a stronger oxidizing agent is added to the nitric acid solution, the corrosion resistance of passive films is further increased. In the past, sodium dichromate was mainly used as an oxidizing agent, but sodium molybdate appeared as an alternative agent due to the environmental problem of sodium dichromate. It is necessary to propose a model of how sodium molybdate affects the corrosion resistance through the action on the surface. In this study, I studied about the formation of passive films on the low nickel duplex stainles steel, STS 329 FLD, by chemical passivation surface treatment. Passive films were formed in nitric acid solutions containing 0 ~ 4.0wt.% sodium molybdate for 30 ~ 60minutes. The morphology, GDOES depth profiles of STS 304 and STS 329 FLD and potentiodynamic anodic polarization curves and EIS were investigated for the formation mechanism of the passive films. Experimental results show that addition of sodium molybdate to the nitric acid solution affected the morphology, the elemental distribution characteristics, and the corrosion resistance characteristics of the passive films. Surface inclusions decreased with the addition of sodium molybdate in the morphology. As a result, the pitting potential increased in the anodic polarization curves, and the roughness profile of the surface increased. As the elemental distribution of the passive films was increased by adding sodium molybdate, the content of iron decreased and chromium increased in the passive films. As a result, the corrosion current(Icorr) decreased in the anodic polarization curves. The electrochemical impedance(EIS) measurements results showed that the capacitance of the passive films increased when sodium molybdate was added. It is considered that not only the increase due to the decrease of the passive films thickness but also the existence of the molybdenum adsorbed on the outermost part of the passive films is due to the formation of the cation selective layer on the outermost surface and the formation of the anion selective layer on the inner passive films. As the passive films formed an electrical bilayer by the adsorption of molybdenum, the corrosion potential(Ecorr) was increased in the anodic polarization curves. In the nitric acid solution with sodium molybdate addition, as the surface treatment time became longer, the content of chromium increased and the corrosion current decreased and the pitting potential increased due to decreased of surface inclusions. The thickness of the passive films decreased with time. The content of molybdenum on the outermost surface decreased in 60minutes, and the capacatance of the electrochemical impedance decreased due to the decrease of molybdenum. Finally, we confirmed the possibility of sodium molybdate as an alternative to sodium dichromate and provided basic guidelines for improving the corrosion resistance of STS 329 FLD1. ์„œ ๋ก  1.1 ์—ฐ๊ตฌ๋ฐฐ๊ฒฝ ๋ฐ ๋ชฉ์  1 1.2 ์—ฐ๊ตฌ๋‚ด์šฉ 3 2. ์ด๋ก ์  ๋ฐฐ๊ฒฝ 2.1 ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ํŠน์„ฑ 4 2.1.1 ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ์žฅ์  5 2.1.2 ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ์•ผ๊ธˆํ•™์  ํŠน์„ฑ 7 2.1.3 ๋“€ํ”Œ๋ ‰์Šค(Duplex) ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ• 11 2.2 ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ํ‘œ๋ฉด์ฒ˜๋ฆฌ 15 2.2.1 ์—ฐ๋งˆ 15 2.2.2 ํ™”ํ•™์  ์ฒ˜๋ฆฌ 19 2.3 ๋ถ€๋™ํƒœ๋ง‰์˜ ํ˜•์„ฑ 25 2.3.1 ๋ถ€๋™ํƒœ๋ง‰์˜ ํ˜•์„ฑ ๊ธฐ๊ตฌ 26 2.3.2 ๋ถ€๋™ํƒœ๋ง‰์˜ ์—ด์—ญํ•™ 28 2.3.3 ๋ถ€๋™ํƒœ๋ง‰์˜ ๋ฐ˜์‘์†๋„๋ก  29 2.3.4 ๋ถ€๋™ํƒœ๋ง‰์˜ ํŠน์„ฑ 34 2.4 ๋ถ€๋™ํƒœ๋ง‰์˜ ํŒŒ๊ดด 42 2.4.1 ๊ณต์‹ 43 2.4.2 ํ‹ˆ๋ถ€์‹ 52 3. ์‹คํ—˜ ๋ฐฉ๋ฒ• 3.1 ์‹œํŽธ ์ œ์ž‘ 54 3.2 ์žฌ๋ฃŒ์˜ ํŠน์„ฑ ๋ถ„์„ ๋ฐ ํ‰๊ฐ€ 58 3.2.1 ๋ ˆ์ด์ € ํ˜„๋ฏธ๊ฒฝ(LSM)์— ์˜ํ•œ ํ‘œ๋ฉด ์กฐ๋„ ์ธก์ • 58 3.2.2 ์ฃผ์‚ฌ์ „์žํ˜„๋ฏธ๊ฒฝ(SEM)์— ์˜ํ•œ ํ‘œ๋ฉด ๋ชฐํฌ๋กœ์ง€ ๊ด€์ฐฐ 58 3.2.3 ์ „์ž๋ฏธ์†Œ๋ถ„์„(EPMA)์— ์˜ํ•œ ํ‘œ๋ฉด์˜ ์›์†Œ๋ณ„ ๋ถ„ํฌ๊ด€์ฐฐ 58 3.2.4 ๊ธ€๋กœ์šฐ๋ฐฉ์ „๋ฐฉ์ถœ๋ถ„๊ด‘๋ฒ•(GDOES)์— ์˜ํ•œ ๊นŠ์ด๋ณ„ ์›์†Œ๋ถ„ํฌ 59 3.2.5 ์ „๊ธฐํ™”ํ•™์  ๋ถ„์„์— ์˜ํ•œ ๋ถ€๋™ํƒœ๋ง‰ ๊ตฌ์กฐ์™€ ๋‚ด์‹ํŠน์„ฑ ๋ถ„์„ 60 4. ์‹คํ—˜ ๊ฒฐ๊ณผ ๋ฐ ๊ณ ์ฐฐ 4.1 ์ €๋‹ˆ์ผˆ ๋“€ํ”Œ๋ ‰์Šค ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•(STS 329 FLD)์˜ ์ž์—ฐ๋ถ€๋™ํƒœ๋ง‰ ํŠน์„ฑ 63 4.1.1 ๋ถ€๋™ํƒœ๋ง‰์˜ ๊นŠ์ด๋ณ„ ์›์†Œ ๋ถ„ํฌ 63 4.1.2 ์ž์—ฐ ๋ถ€๋™ํƒœ๋ง‰์˜ ๋‚ด์‹ ํŠน์„ฑ 69 4.2 ์งˆ์‚ฐ ํ‘œ๋ฉด์ฒ˜๋ฆฌ ์ค‘ ์ฒจ๊ฐ€ํ•œ Na2MoO4 ๋†๋„์— ๋”ฐ๋ฅธ ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜๋ถ€๋™ํƒœ๋ง‰ ํŠน์„ฑ 72 4.2.1 ๋ถ€๋™ํƒœ๋ง‰์˜ ๋ชฐํฌ๋กœ์ง€ ๊ด€์ฐฐ 72 4.2.2 ๋ถ€๋™ํƒœ๋ง‰์˜ ๊นŠ์ด๋ณ„ ์›์†Œ ๋ถ„ํฌ 81 4.2.3 ๋ถ€๋™ํƒœ๋ง‰์˜ ํ‘œ๋ฉด ํŠน์„ฑ ๋ถ„์„ 100 4.2.4 ๋ถ€๋™ํƒœ๋ง‰์˜ ๋‚ด์‹ ํŠน์„ฑ 106 4.3 ์งˆ์‚ฐ ์šฉ์•ก ์ค‘ ์ฒจ๊ฐ€ํ•œ 0.5wt.% Na2MoO4 ํ‘œ๋ฉด์ฒ˜๋ฆฌ ์‹œ๊ฐ„์— ๋”ฐ๋ฅธ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ๋ถ€๋™ํƒœ๋ง‰ ํŠน์„ฑ 108 4.3.1 ๋ถ€๋™ํƒœ๋ง‰์˜ ๋ชฐํฌ๋กœ์ง€ ๊ด€์ฐฐ 108 4.3.2 ๋ถ€๋™ํƒœ๋ง‰์˜ ๊นŠ์ด๋ณ„ ์›์†Œ ๋ถ„ํฌ 114 4.3.3 ๋ถ€๋™ํƒœ๋ง‰์˜ ํ‘œ๋ฉด ํŠน์„ฑ ๋ถ„์„ 125 4.3.4 ๋ถ€๋™ํƒœ๋ง‰์˜ ๋‚ด์‹ ํŠน์„ฑ 127 4.4 ์งˆ์‚ฐ ํ‘œ๋ฉด์ฒ˜๋ฆฌํ•œ ์ €๋‹ˆ์ผˆ ์Šคํ…Œ์ธ๋ฆฌ์Šค๊ฐ•์˜ ๋ถ€๋™ํƒœ๋ง‰์˜ ํ˜•์„ฑ ๋ฉ”์นด๋‹ˆ์ฆ˜ 130 5. ๊ฒฐ ๋ก  134 ์ฐธ๊ณ  ๋ฌธํ—Œ 136Maste

    An anesthetic experience in a patient with Seckel syndrome: A case report

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    Seckel syndrome is an autosomal recessive, primordial dwarfism. The clinical symptoms and signs include severe intrauterine and postnatal growth retardation, nanocephaly, proportional dwarfism, bird-like faces, beak-like triangular nose, and mental retardation. We report a successful anesthetic management including endotracheal intubation with the GlideScope(R) video laryngoscope in an 18-year old man with Seckel syndrome for curettage of chronic osteomyelitis of pelvic boneope

    Treatment of a Twelfth Rib Syndrome

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    Twelfth rib syndrome is thought to be due to intercostal nerve irritation by a mobile twelfth rib, and presents with upper abdominal pain, or low thoracic pain. This syndrome appears to be a fairly common entity and diagnosis is based on clinical findings. Patients with twelfth rib syndrome can be misdiagnosed when it has been overlooked. We report a case of a 34-year-old male along with a presentation of twelfth rib syndrome. One patient was transferred from urologic clinic to pain clinic due to right flank pain and admitted. The patient had direct tenderness on twelfth rib area and direct tenderness was reproducible. Pain increased when the patient flexed laterally, rotated trunk. There were no specific abnormal findings in laboratory test, electrocardiogram, and radiologic examination. After intercostal nerve block and epidural block, pain decreased and the patient was dischargedope

    Chronic Mandibular Osteomyelitis with Normal Value of C-reactive Protein

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    A 58-year-old male was referred to our pain clinic with right lower facial pain of visual analogue scale 8/10 cm. One week ago, his right lower 3rd molar was extracted for vesicles at the buccal mucosal membrane and right lower facial hypoesthesia. Immunoserologic tests revealed negative varicella-zoster virus immunoglobulin-M, positive immunoglobulin-G and normal value of C-reactive protein. Buccal mucosa biopsy revealed squamous epithelial hyperplasia. Medications for pain control was pregabalin 150 mg PO bid, amitriptyline 10 mg PO hs, fentanyl patch 12.5 ีŒg/h, carbamazepine 200 mg PO hs. C-arm guided block and pulsed radiofrequency lesionning was performed at mandibular branch of the right trigeminal nerve. And then VAS score was reduced to 4/10 cm. On facial bone CT, facial MRI and 3-phase bone scan, chronic osteomyelitis was suspected on the right mandible. Herpes zoster by atypical clinical manifestations was excluded. After additional biopsy and culture on lesion, antibiotics were used to treat the osteomyelitis and surgical follow-up was planned for surgical removal of necrotic tissue.ope

    The Expression of the Ca++ Channel ฮฑ2ฮด Subunit and TRPM8 in the Dorsal Root Ganglion of Sympathetically Maintained Pain and Sympathetic Independent Pain Rat Models

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    Background Peripheral nerve injury induces up-regulation of the calcium channel alpha2delta (ฮฑ2ฮด) subunit and TRPM8 in the dorsal root ganglion (DRG) which might contribute to allodynia development. We investigated the expression of the ฮฑ2ฮด subunit and TRPM8 in the DRG of sympathetically maintained pain (SMP) and sympathetic independent pain (SIP) rat model. Methods For the SMP model, the L5 and L6 spinal nerves were ligated tightly distal to the DRG. For the SIP model, the tibial and sural nerves were transected, while the common peroneal nerve was spared. After a 7 day postoperative period, tactile and cold allodynia were assessed using von Frey filaments and acetone drops, respectively. Expression of the ฮฑ2ฮด subunit and TRPM8 in the L5 and L6 DRG were subsequently examined by a Western blot. Results There were no significant differences between the two models for the thresholds of tactile and cold allodynia. Expression of the ฮฑ2ฮด subunit in the ipsilateral DRG to the injury was increased as determined on a Western blot as compared to that in the contralateral or sham-operated DRG of the SMP model, but there was no difference in expression seen with the use of the SIP model. There was no difference in the expression of TRPM8 in the ipsilateral DRG to the injury and the contralateral or sham-operated DRG of either model. Conclusions Up-regulation of the ฮฑ2ฮด subunit in injured DRG may play a role that contributes to tactile allodynia development in SMP, but not TRPM8 to cold allodynia after peripheral nerve injurope

    Incidence and Risk Factors of Postoperative Nausea and Vomiting in Patients with Fentanyl-Based Intravenous Patient-Controlled Analgesia and Single Antiemetic Prophylaxis

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    PURPOSE: We evaluated the incidence and risk factors of postoperative nausea and vomiting (PONV) in patients with fentanyl-based intravenous patient-controlled analgesia (IV-PCA) and single antiemetic prophylaxis of 5-hydroxytryptamine type 3 (5 HTโ‚ƒ)-receptor antagonist after the general anesthesia. MATERIALS AND METHODS: In this retrospective study, incidence and risk factors for PONV were evaluated with fentanyl IV-PCA during postoperative 48 hours after various surgeries. RESULTS: Four hundred-forty patients (23%) of 1878 had showed PONV. PCA was discontinued temporarily in 268 patients (14%), mostly due to PONV (88% of 268 patients). In multivariate analysis, female, non-smoker, history of motion sickness or PONV, long duration of anesthesia (>180 min), use of desflurane and intraoperative remifentanil infusion were independent risk factors for PONV. If one, two, three, four, five, or six of these risk factors were present, the incidences of PONV were 18%, 19%, 22%, 31%, 42%, or 50%. Laparoscopic surgery and higher dose of fentanyl were not risk factors for PONV. CONCLUSION: Despite antiemetic prophylaxis with 5 HTโ‚ƒ-receptor antagonist, 23% of patients with fentanyl-based IV-PCA after general anesthesia showed PONV. Long duration of anesthesia and use of desflurane were identified as risk factors, in addition to risk factors of Apfel's score (female, non-smoker, history of motion sickness or PONV). Also, intraoperative remifentanil infusion was risk factor independent of postoperative opioid use. As the incidence of PONV was up to 50% according to the number of risk factors, risk-adapted, multimodal or combination therapy should be applied.ope

    Participation of K(ATP) Channels in the Antinociceptive Effect of Pregabalin in Rat Formalin Test

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    BACKGROUND: Pregabalin is an anticonvulsant and analgesic agent that interacts selectively with the voltage-sensitive-Ca(2+)-channel alpha-2-delta subunit. The aim of this study was to evaluate whether the analgesic action of intrathecal (IT) pregabalin is associated with K(ATP) channels in the rat formalin test. METHODS: IT PE-10 catheters were implanted in male Sprague-Dawley rats (250-300 g) under inhalation anesthesia using enflurane. Nociceptive behavior was defined as the number of hind paw flinches during 60 min after formalin injection. Ten min before formalin injection, IT drug treatments were divided into 3 groups: normal saline (NS) 20 ยตl (CON group); pregabalin 0.3, 1, 3 and 10 ยตg in NS 10 ยตl (PGB group); glibenclamide 100 ยตg in DMSO 5 ยตl with pregabalin 0.3, 1, 3 and 10 ยตg in NS 5 ยตl (GBC group). All the drugs were flushed with NS 10 ยตl. Immunohistochemistry for the K(ATP) channel was done with a different set of rats divided into naรฏve, NS and PGB groups. RESULTS: IT pregabalin dose-dependently decreased the flinching number only in phase 2 of formalin test. The log dose response curve of the GBC group shifted to the right with respect to that of the PGB group. Immunohistochemistry for the K(ATP) channel expression on the spinal cord dorsal horn showed no difference among the groups 1 hr after the formalin test. CONCLUSIONS: The antinociceptive effect of pregabalin in the rat formalin test was associated with the activation of the K(ATP) channel. However, pregabalin did not induce K(ATP) channel expression in the spinal cord dorsal horn.ope

    Alternative Method of Retrocrural Approach during Celiac Plexus Block Using a Bent Tip Needle

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    BACKGROUND: This study sought to determine safe ranges of oblique angle, skin entry point and needle length by reviewing computed tomography (CT) scans and to evaluate the usefulness of a bent tip needle during celiac plexus block (CPB). METHODS: CT scans of 60 CPB patients were reviewed. Image of the uppermost margin of L2 vertebral body was used to measure the minimal and maximal oblique angles and the distances from the midline to skin puncture point. The imaginary needle trajectory distance was calculated by three-dimensional measurement. When the procedure was performed by using a 10ยฐ bent tip needle under a 20ยฐ oblique X-ray fluoroscopic view, the distance (GF/G'F) from the midline to the actual puncture site was measured. RESULTS: The imaginary safe oblique angle range was 26.4-34.2ยฐ and 27.7-36.0ยฐ on the right and left, respectively. The distance from the midline to skin puncture point was 6.1-7.6 cm on the right and 6.3-7.6 cm on the left. The needle trajectory distance at minimal angle was 9.6-11.6 cm on the right and 9.5-11.5 cm on the left. The distance of GF/G'F was 5.1-6.5 cm and 5.0-6.4 cm on the right and left, respectively. All imaginary parameters were correlated with BMI except for GF/G'F. All complications were mild and transient. CONCLUSIONS: We identified safe values of angles and distances using a straight needle. Furthermore, using a bent tip needle under a 20ยฐ oblique fluoroscopic view, we could safely perform CPB with smaller parameter values.ope

    Significance of active range of motion as pain indicator in cervical facet joint pain

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    ์˜ํ•™๊ณผ/์„์‚ฌ[ํ•œ๊ธ€]์„œ๋ก : ๊ฒฝ๋ถ€ํ†ต์ด ์žˆ๋Š” ํ™˜์ž์—์„œ ๊ฒฝ์ถ”์˜ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„์˜ ์ธก์ •์€ ์ผ์ƒ์ ์œผ๋กœ ํ–‰ํ•ด์ง€๋Š” ์ดํ•™์  ๊ฒ€์‚ฌ์ด๋‹ค. ๋ณธ ์—ฐ๊ตฌ๋Š” ์ผ๋ฐ˜์ ์ธ ์ค‘๋ ฅ๊ฐ๋„๊ธฐ๋ฅผ ์‚ฌ์šฉํ•˜์—ฌ ๊ฒฝ๋ถ€ํ†ต์ด ์žˆ๋Š” ํ™˜์ž์—์„œ ๊ฒฝ์ถ” ํ›„์ง€ ๋‚ด์ธก์ง€ ์ฐจ๋‹จ์ˆ  ์ „ ํ›„์— ๊ฒฝ์ถ”์˜ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„๋ฅผ ์ธก์ •ํ•˜์—ฌ ๊ทธ ๋ณ€ํ™”๋ฅผ ๊ด€์ฐฐํ•˜์˜€์œผ๋ฉฐ, ๊ทธ ๋ณ€ํ™”๊ฐ€ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€๋Š” ์–ด๋–ค ์ƒ๊ด€๊ด€๊ณ„๊ฐ€ ์žˆ๋Š”์ง€ ์‚ดํŽด๋ณด๊ธฐ ์œ„ํ•œ ๊ฒƒ์ด๋‹ค. ๊ฒฝ์ถ”๋ถ€ ํ›„์ง€ ๋‚ด์ธก์ง€ ์ฐจ๋‹จ์ˆ  ์‹œ์ˆ  ์ „ํ›„์— ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„๋ฅผ ์ธก์ •ํ•˜์—ฌ, ์‹œ์ˆ  ์ „์— ๋น„ํ•ด์„œ ์‹œ์ˆ  ํ›„์— ์–ด๋–ป๊ฒŒ ๋ณ€ํ™”๋˜๋Š”์ง€ ํ™•์ธํ•˜๊ณ , ์‹œ์ˆ  ์ „๊ณผ ์‹œ์ˆ  ํ›„ 1์‹œ๊ฐ„, ์‹œ์ˆ  ํ›„ 1์ฃผ์ผ์— ์ธก์ •๋œ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜ ๋ฐ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„ ์ž์ฒด๊ฐ€ ์ƒ๊ด€๊ด€๊ณ„๊ฐ€ ์žˆ๋Š”์ง€ ์‚ดํŽด๋ณด๊ณ , ์‹œ์ˆ  ์ „ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€ ์‹œ์ˆ  ์ „ํ›„ ์ธก์ •๋œ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„๋ณ€ํ™”๊ฐ€ ์ƒ๊ด€๊ด€๊ณ„๊ฐ€ ์žˆ๋Š”์ง€ ์‚ดํŽด๋ณด๊ณ ์ž ํ•œ๋‹ค.๋Œ€์ƒ ๋ฐ ๋ฐฉ๋ฒ•: ๋ณ‘์› ์œค๋ฆฌ์œ„์›ํšŒ์˜ ์‹ฌ์‚ฌ๋ฅผ ํ†ต๊ณผํ•˜๊ณ , ๋Œ€์ƒํ™˜์ž์—๊ฒŒ ๋ณธ ์—ฐ๊ตฌ์˜ ๋ฐฉ๋ฒ•๊ณผ ๋ชฉ์ ์„ ์„ค๋ช…ํ•˜๊ณ  ํ™˜์ž์˜ ๋™์˜ ํ•˜์— ์—ฐ๊ตฌ๋ฅผ ์‹œํ–‰ํ•˜์˜€๋‹ค. 2009๋…„ 3์›”๋ถ€ํ„ฐ 6์›” ์‚ฌ์ด์— ๋ณธ์› ํ†ต์ฆํด๋ฆฌ๋‹‰์„ ๋ฐฉ๋ฌธํ•œ 18์„ธ์—์„œ 65์„ธ ์‚ฌ์ด์˜ ๊ฒฝ๋ถ€ํ†ต ์™ธ์—๋Š” ํŠน๋ณ„ํ•œ ์งˆํ™˜์„ ๊ฐ€์ง€๊ณ  ์žˆ์ง€ ์•Š์€ ํ™˜์ž๋“ค์„ ๋Œ€์ƒ์œผ๋กœ ํ•˜์˜€๋‹ค. ๊ฒฝ๋ถ€ํ†ต ์ค‘์—์„œ ํ›„๊ด€์ ˆํ†ต(facet joint pain)์„ ๊ฐ€์ง„ ํ™˜์ž๋“ค๋งŒ์„ ๋Œ€์ƒ์œผ๋กœ ํ•˜์˜€๊ณ , ์‹ ๊ฒฝ๋ฟŒ๋ฆฌ๋ณ‘์ฆ(radiculopathy)์ด ์žˆ๊ฑฐ๋‚˜, ์ถ”๊ฐ„ํŒ์„ฑ ํ†ต์ฆ(discogenic pain)์ด ์˜์‹ฌ๋˜๋Š” ํ™˜์ž๋Š” ์ œ์™ธํ•˜์˜€๋‹ค. ์ด๋Ÿฐ ํ™˜์ž๋“ค ์ค‘์—์„œ 2์ฃผ๊ฐ„ ๋ฌผ๋ฆฌ์น˜๋ฃŒ๋‚˜ ์•ฝ๋ฌผ์น˜๋ฃŒ๋ฅผ ์‹ค์‹œํ•˜์—ฌ ํ†ต์ฆ ์กฐ์ ˆ์ด ๋˜์ง€ ์•Š๋Š” ๊ฒฝ์ถ” ํ›„๊ด€์ ˆํ†ต ํ™˜์ž 48๋ช…์„ ๋Œ€์ƒ์œผ๋กœ ํ•˜์˜€๋‹ค. ์‹œ์ˆ  ์ „ 1์ฐจ๋กœ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„์™€ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜(VAS score)๋ฅผ ์ธก์ •ํ•˜์˜€๊ณ , ๊ฒฝ์ถ” ํ›„์ง€ ๋‚ด์ธก์ง€ ์ฐจ๋‹จ์ˆ ์„ ์‹œํ–‰ํ•œ ํ›„, 1์‹œ๊ฐ„ ํ›„์— 2์ฐจ๋กœ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„์™€ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜๋ฅผ ์ธก์ •ํ•˜์˜€๋‹ค. 1์ฃผ์ผ ํ›„์— 3์ฐจ๋กœ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„์™€ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜๋ฅผ ์ธก์ •ํ•˜์˜€๋‹ค. ์‹œ์ˆ  ์ „ ์ธก์ •์น˜์™€ 1์‹œ๊ฐ„, 1์ฃผ์ผ ํ›„ ์ธก์ •์น˜์˜ ์‹œ๊ฐ„์— ๋”ฐ๋ฅธ ๋ณ€ํ™”์˜ ์œ ์˜์„ฑ์„ ๊ฒ€์ฆํ•˜์˜€๋‹ค. ์ „์ฒด ํ™˜์ž์—์„œ ์‹œ์ˆ  ์ „ํ›„์— ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„์˜ ์ƒ๊ด€๊ด€๊ณ„๋ฅผ ํ™•์ธํ•˜์˜€๋‹ค. ์–‘์ชฝ์„ ์‹œ์ˆ ํ•œ ๊ตฐ์„ ์ œ์™ธํ•˜๊ณ  ์˜ค๋ฅธ์ชฝ์„ ์‹œ์ˆ ํ•œ ๊ตฐ๊ณผ ์™ผ์ชฝ์„ ์‹œ์ˆ ํ•œ ๊ตฐ์˜ ํ•ฉ, 30๋ช…์— ๋Œ€ํ•ด์„œ, ์‹œ์ˆ ํ•œ ์ชฝ์„ ๊ธฐ์ค€์œผ๋กœ ๋™์ธก(ipsilateral), ๋ฐ˜๋Œ€์ธก(contralateral)์œผ๋กœ ๋‚˜๋ˆ„์–ด ๊ฐ๊ฐ ์‹œ์ˆ  ์ „ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€ ์‹œ์ˆ  ํ›„ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„๋ณ€ํ™”์˜ ์ƒ๊ด€๊ด€๊ณ„๋ฅผ ํ™•์ธํ•˜์˜€๋‹ค. ๊ฒฐ๊ณผ: 48๋ช…(์˜ค๋ฅธ์ชฝ ์ฐจ๋‹จ 12๋ช…, ์™ผ์ชฝ ์ฐจ๋‹จ 18๋ช…, ์–‘์ชฝ ์ฐจ๋‹จ 18๋ช…)์˜ ํ™˜์ž์—์„œ ๊ฒฝ์ถ” ํ›„์ง€ ๋‚ด์ธก์ง€ ์ฐจ๋‹จ ์ „, ์ฐจ๋‹จ ํ›„ 1์‹œ๊ฐ„, ์ฐจ๋‹จ ํ›„ 1์ฃผ์ผ์— ์ธก์ •ํ•œ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜ ๋ฐ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„๋ฅผ ๋ฐ˜๋ณต์ธก์ •๋ถ„์‚ฐ๋ถ„์„(repeated measured ANOVA)์œผ๋กœ ๋ถ„์„ํ•œ ๊ฒฐ๊ณผ ๋ชฉ์˜ ๊ตด๊ณก์„ ์ œ์™ธํ•œ ๋ชจ๋“  ๊ฐ’์—์„œ(p<0.05) ํ†ต๊ณ„์ ์œผ๋กœ ์œ ์˜ํ•œ ๋ณ€ํ™”๋ฅผ ๋ณด์˜€๋‹ค. ์‹œ์ˆ  ํ›„ 1์‹œ๊ฐ„, ์‹œ์ˆ  ํ›„ 1์ฃผ์ผ์—์„œ ๊ฐ๊ฐ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜ -30.1%, -38.6%, ๋ชฉ์˜ ์‹ ์ „ 9.6%, 10.2%, ๋ชฉ์˜ ์˜ค๋ฅธ์ชฝ ์ธก๋ฉด ๊ตฝํž˜ 18.5%, 15.5%, ์™ผ์ชฝ ์ธก๋ฉด ๊ตฝํž˜ 8.5%, 10.9%, ๋ชฉ์˜ ์˜ค๋ฅธ์ชฝ ํšŒ์ „ 9.2%, 13.9%, ์™ผ์ชฝ ํšŒ์ „ 12%, 17.7%์˜ ๋ณ€ํ™”๊ฐ€ ์žˆ์–ด ์‹œ์ˆ  ์ „ํ›„ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„๋Š” ๊ฐ๊ฐ ํ˜ธ์ „์„ ๋ณด์˜€์ง€๋งŒ, ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„์˜ ์ƒ๊ด€๊ด€๊ณ„๋Š” ๋‚ฎ์•˜๋‹ค. ๋‚˜์ด, ์„ฑ๋ณ„, ์‹œ์ˆ ๋ถ„์ ˆ์˜ ์ˆ˜, ์‹œ์ˆ ํ•œ ์ชฝ์˜ ์ฐจ์ด์— ์˜ํ•œ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„์˜ ์œ ์˜ํ•œ ์ฐจ์ด๋Š” ์—†์—ˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜, ์–‘์ชฝ์„ ์‹œ์ˆ ํ•œ 18๋ช…์„ ์ œ์™ธํ•œ 30๋ช…์—์„œ ์‹œ์ˆ  ์ „ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€ ์‹œ์ˆ  1์ฃผ์ผ ํ›„์˜ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„๋ณ€ํ™”์˜ ์ƒ๊ด€๊ด€๊ณ„์—์„œ๋Š” ๋™์ธก, ๋ฐ˜๋Œ€์ธก ํšŒ์ „์—์„œ ๊ฐ๊ฐ p=0.017 (R=-0.433), p=0.042 (R=-0.374)๋กœ ํ†ต๊ณ„์ ์œผ๋กœ ์œ ์˜ํ•œ ์—ญ ์ƒ๊ด€๊ด€๊ณ„๊ฐ€ ์žˆ๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚˜์„œ ์‹œ์ˆ  ์ „ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜๊ฐ€ ๋‚ฎ์€ ํ™˜์ž์ผ์ˆ˜๋ก ์‹œ์ˆ  ํ›„ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„์˜ ์ฆ๊ฐ€๊ฐ€ ์ปค์ง€๋Š” ๊ฒฝํ–ฅ์„ ๋ณด์—ฌ ์ฃผ์—ˆ๋‹ค.๊ฒฐ๋ก : ๊ฒฝ์ถ” ํ›„๊ด€์ ˆํ†ต ํ™˜์ž์—์„œ ๊ฒฝ์ถ” ํ›„์ง€ ๋‚ด์ธก์ง€ ์ฐจ๋‹จ์ˆ  ์‹œํ–‰ ํ›„ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜๊ฐ€ ๊ฐ์†Œํ•˜์˜€์œผ๋ฉฐ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„๋Š” ๋ชฉ์˜ ๊ตด๊ณก์„ ์ œ์™ธํ•˜๊ณ  ์œ ์˜ํ•˜๊ฒŒ ์ฆ๊ฐ€ํ•˜์˜€๋‹ค. ๊ฐ ์ธก์ • ์‹œ์ ์—์„œ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€ ๋Šฅ๋™์  ์šด๋™๋ฒ”์œ„์˜ ์ƒ๊ด€๊ด€๊ณ„๋Š” ๋†’์ง€ ์•Š์•˜๋‹ค. ์–‘์ธก์„ ์ฐจ๋‹จํ•œ 18๋ช…์„ ์ œ์™ธํ•œ 30๋ช…์—์„œ ์‹œ์ˆ  ์ „ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์™€ ์‹œ์ˆ  1์ฃผ์ผ ํ›„ ๋™์ธก, ๋ฐ˜๋Œ€์ธก ํšŒ์ „์˜ ๋ณ€ํ™” ์‚ฌ์ด์— ํ†ต๊ณ„์ ์œผ๋กœ ์œ ์˜ํ•œ ์—ญ ์ƒ๊ด€๊ด€๊ณ„๊ฐ€ ์žˆ์—ˆ๋‹ค. ๋”ฐ๋ผ์„œ, ์‹œ์ˆ  ์ „ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜๊ฐ€ ๋†’์€ ํ™˜์ž๋Š” ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜์˜ ๊ฐ์†Œ๋ฅผ ํ†ต์ฆํ‰๊ฐ€์ง€ํ‘œ๋กœ ์‚ผ์„ ์ˆ˜ ์žˆ๊ณ , ์‹œ์ˆ  ์ „ ์‹œ๊ฐํ†ต์ฆ์ฒ™๋„ ์ ์ˆ˜๊ฐ€ ๋‚ฎ์€ ํ™˜์ž๋Š” ์‹œ์ˆ  ํ›„ 1์ฃผ์ผ์— ํšŒ์ „๋ณ€ํ™”๋ฅผ ์ธก์ •ํ•˜์—ฌ ํ†ต์ฆํ‰๊ฐ€์ง€ํ‘œ๋กœ ์‚ผ์„ ์ˆ˜ ์žˆ์„ ๊ฒƒ์ด๋‹ค. [์˜๋ฌธ]Introduction: The cervical active range of motion should be checked daily by a physical examination in patients with neck pain. This study examined the change in the active range of motion and the visual analogue scale score after a cervical medial branch block and the correlation between the active range of motion and visual analogue scale score after a cervical medial branch block using a commonly used gravity-based goniometer. The visual analogue scale score, active range of motion was measured before and after a cervical medial branch block, and the correlation between a visual analogue scale score before the cervical medial branch blocks and the change in the active range of motion at 1 hour, and 1 week after the cervical medial branch block was examined. The correlation between the visual analogue scale score and active range of motion before, 1 hour and 1 week after the cervical medial branch block was also examined. Objectives and Methods: After gaining approval of the hospital ethical committee, the aims and method of this study were explained to the patients. The subjects were 48 patients who visited our pain clinic from March 2009 to June 2009. The patients were 18-65 years old and had no disease except for neck pain. Patients with cervical radiculopathy and discogenic pain were excluded. Patients with facet joint pain that was not relieved by physical therapy and medication for 2 weeks were included. The active range of motion, visual analogue scale score was measured before, 1 hour and 1 week after the cervical medial branch block. The change in the active range of motion, visual analogue scale score was examined at each time. Excluding the group given injections in both sides, the remaining 30 patients given a right and left injection were divided into the ipsilateral, and contralateral groups, respectively. The correlation between the visual analogue scale score before the cervical medial branch block, and the change in the active range of motion in the ipsilateral and contralateral group (we excluded flexion and extension) was examined. The correlation between the visual analogue scale score and the active range of motion was investigated in all patients at each time. Results: An analysis of 48 patients (right 12, left 18, both 18) by repeated measured ANOVA showed significant changes in the active the cervical medial branch block was examined. The correlation between the visual analogue scale score and active range of motion before, 1 hour and 1 week after the cervical medial branch block was also examined. Objectives and Methods: After gaining approval of the hospital ethical committee, the aims and method of this study were explained to the patients. The subjects were 48 patients who visited our pain clinic from March 2009 to June 2009. The patients were 18-65 years old and had no disease except for neck pain. Patients with cervical radiculopathy and discogenic pain were excluded. Patients with facet joint pain that was not relieved by physical therapy and medication for 2 weeks were included. The active range of motion, visual analogue scale score was measured before, 1 hour and 1 week after the cervical medial branch block. The change in the active range of motion, visual analogue scale score was examined at each time. Excluding the group given injections in both sides, the remaining 30 patients given a right and left injection were divided into the ipsilateral, and contralateral groups, respectively. The correlation between the visual analogue scale score before the cervical medial branch block, and the change in the active range of motion in the ipsilateral and contralateral group (we excluded flexion and extension) was examined. The correlation between the visual analogue scale score and the active range of motion was investigated in all patients at each time. Results: An analysis of 48 patients (right 12, left 18, both 18) by repeated measured ANOVA showed significant changes in the active range of motion except for flexion, and the visual analogue scale score before, 1 hour and 1 week after the cervical medial branch block. The change at 1 hour and 1 week after cervical medial branch block was respectively, -30.1% and -38.6% in the visual analogue scale score, 9.6% and 10.2% in extension, 18.5% and 15.5% in right lateral bending, 8.5% and 10.9% in left lateral bending, 9.2% and 13.9% in right rotation, and 12% and 17.7% in left rotation. There was no correlation between the visual analogue scale score and active range of motion at any time, even though the VAS and active range of motion had improved. In 30 patients injected on either side, there was an inverse correlation between the visual analogue scale score before the cervical median branch block and the change in the ipsilateral, contralateral rotation at 1 week after the cervical medial branch block (p = 0.017 and 0.042; R=-0.433 and -0.0374). Conclusions: In patients with facet joint pain, there were significant decreases in the visual analogue scale score, and increases in the active range of motion after the cervical medial branch block. The visual analogue scale score was not associated with the active range of motion at each time point. The change in the ipsilateral and contralateral rotation at 1 week after the cervical medial branch block was inversely correlated with the visual analogue scale score before the cervical medial branch block. In patients with a high VAS before the cervical medial branch block, a low VAS would be a pain indicator. However, in patients with a low VAS before the cervical medial branch block, monitoring the increase in ipsilateral or contralateral rotation of the neck 1 week after a cervical medial branch block would be a new method for assessing the level of pain.ope
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