41 research outputs found
BLOOD VISCOSITY CHANGE IN ORAL SQUAMOUS CELL CARCINOMA XENOTRANSPLANTED NUDE MICE
It is well known that malignant tumor have hypoxic cell fraction, which is radio resistant and is one of the most important cause of local recurrence after radiotherapy. One of the causes of hypoxia in tumor is blood flow decrease due to increase in blood flow resistance and one of the causes of increased blood flow resistance could be attributed to the increase in blood viscosity. For the evaluation of the change of blood viscosity in oral cancer, experiments were carried out to test the change of blood viscosity among the normal control and xenografted oral cancer nude mice. Relative viscosity measured against distilled water was for normal control, and for tumor bearing mice at the first time of blood sampling in experimental period ( ). There was no statistically significant difference between the control group and experimental group (p>0.05). However, as the tumor grew, significant difference of blood viscosity was detected at the third time of blood sampling (control group:, and experimental group:2003λ
λ νκ΅νμ μ§ν₯μ¬
CHANGE OF BLOOD VISCOSITY AND DEFORMABILITY IN ORAL SQUAMOUS CELL CARCINOMA PATIENTS
Malignant tumor have hypoxic cell fraction, which makes radio-resistant and hypoxia in tumor is a result from the blood flow decrease caused by increase in blood flow resistance. Blood viscosity increase is major factor of increased blood flow resistance and it could be attributed to the decrease in blood deformability index. For the evaluation of the change of blood viscosity and blood deformability in oral squamous cell carcinoma, we perform the test of the change of those factors between the normal control group and oral squamous cell carcinoma cell patient group. Relative viscosity measured against distilled water was for normal control group, and for the SCC patient group and there was statistical significance between the groups. However, there was no significant difference between the groups in blood viscosity between the groups by tumor size (T1+T2 vs T3+T4). Also, there was no significant difference between the normal control group and SCC patient group in blood deformability index and between the groups by tumor size (T1+T2 vs T3+T4). Increase in blood viscosity was confirmed with this study and it can be postulated that modification blood viscosity might contribute to decrease of hypoxia fraction in oral squamous cell carcinoma, thus improve the effect of radiotherapy and it can be assumed that the main factor of blood viscosity increase is not decrease of blood deformability in oral squamous cell carcinoma.2003λ
λ νκ΅νμ μ§ν₯μ¬
INTERNAL VS. RIGID EXTERNAL DISTRACTION DEVICE FOR THE MAXILLARY HYPOPLASIA OF CLEFT PATIENTS
Distraction osteogenesis for the advancement of hypoplastic maxilla of cleft patients has shown successful results. In this report, rigid external distraction(RED) system and internal distraction device were used for maxillary advancement. Each system has its advantages and disadvantages. Larger amount of advancement can be achieved with RED system. But complex external device may give patients psychological stress. Internal device is invisible. However its distraction amount have limitation for the advancement (< 20mm) and the vector cannot be changed freely during distraction. The authors treated five cleft patients with maxillary hypoplasia(three with RED system and two with internal distractor). Their results were clinically satisfactory. We present the pros and cons of RED and internal system for maxillary distraction osteogenesis
BLEPHAROPLASTY BY VARIOUS CAUSES
μ¬λ―Έμ μΈ μ΄μ λ₯Ό ν¬ν¨ν μ¬λ¬ κ°μ§ μμΈμ μν μκ²μ±νμ μ μ μλ±μ΄ μ¬μ©ν λ°©λ², μκ²μ±νμ μ λ°κ³ μ νλ λκΈ°, ν©λ³μ¦ λ±μ λ³΄κ³ νλ©° κ΅λ΄μ ν±μΌκ΅΄μΈκ³Όμμ¬λ€μ μλ‘μ΄ μ§λ£ μμμΌλ‘μ μλ©΄λΆ μ°μ‘°μ§λ―Έμ©μμ μ κ΄ν κ΄μ¬κ³Ό λ
Έλ ₯μ κΈ°λνλ€
FALSE ANEURYSM IN INTERNAL MAXILLARY ARTERY
ꡬκ°μ
μλ©΄ μμμμμ μΈμμ μν λ΄μ
λλ§₯μ κ°μ± λλ§₯λ₯λ κ·Ήν λλ¬Έ λ³λ³μΌλ‘ μ μλ€μ μμΈ λνκ΅ μΉκ³Όλ³μ ꡬκ°μ
μλ©΄μΈκ³Όμμ 1λ‘λ₯Ό μΉννμλ€. κ·Έ μμΈμ μΈμμ μν νμ
κ³Όλ 골μ , κ΄νμ μ 볡μ μμ μμμ μΈμ λλ λ λ€λ₯Ό κ³ λ €ν΄ λ³Ό μ μμμΌλ©° μμμ μΌλ‘ λ°λμ± μ‘μ,μ΄μ§ κ°λ₯ν λ§₯λμ΄ μμκ³ μ μ€ κ³Όλ€ μΆνμ μμμ 보μλ€. λ³μλ νκ΄ μ‘°μμ μ μν΄ νμ§λμμΌλ©°, μμ μ λ‘ μΉλ£νμλ€. κ°μ± λλ§₯λ₯λ μλͺ
μ μνν μ λμ κ³Όλ€ μΆνμ μΌμΌν¬ μ μμΌλ―λ‘ κ·Έ μ§λ¨κ³Ό μΉλ£λ μ€μνλ€. νκ΄ μ‘°μμ μ μμμ μ¦μμ λν νμ€ν μ§λ¨μ κ°λ₯μΌ ν΄ μ£Όλ©° μ΄λ₯Ό μ΄μ©ν μμ μ μ κ΄νμ κ²°μ°°λ²μ λΉν΄ μ₯μ μ κ°μ§λ―λ‘ μ’μ μΉλ£λ²μ΄ λ μ μλ€.보건볡μ§λΆ 보건μλ£κΈ°μ μ§ν₯μ¬
Total esthetic orthognathic surgery : 1 . New esthetic lines and inter-esthetic line angle
Improvement of orthognathic surgical techniques make it possible to design esthetic surgical correction for total esthetic face.
In order to find the esthetic line which guide esthetic surgical correction in patients of orthognathic surgery, cephalometric soft tissue analysis of esthetic faces were performed. In esthetic Korean young adults, 25 males and 25 females who were within 1 S. D. of E-line, ANB, P/A facial height ratio, were analyzed
in natural position keeping their face eye level.
1. Sn position is constant in males and females. The Sn-N1-N' Vertical plane angle is 5.3Λ in both sexes.
Sn is positioned in front of 5 mm in female 7 mm in male from the N' vertical plane.
2. The Sn-Ls line make constant angle to horizontal plane with 72.5Λ in both sexes, which is called
upper esthetic line". The Ls-Pg' line makes constant angle to 72.4Λ (range 72.2Λ in female to 72.6Λ in male), which is called lower esthetic line.
3. When inter-esthetic line angle (the Sn-Ls line to Ls-Pg' line) has 144.9". lower third face has esthetic upper and lower lip.
4. In treatment planning, Sn is fist corrected in proper position, and then upper and lower esthetic line are established with the angle of 144.9. The maxilla is moved to tangent Ls to the upper esthetic line, and mandible is moved to tangent Li and Pgl to the lower esthetic line, according to the "y"-shaped esthetic lines, then lower third face showes esthetics.λ³Έ λ
Όλ¬Έμ 1992λ
λ μμΈλνλ³μ μ§μ μ°κ΅¬λΉμ 보쑰λ₯Ό λ°μκ²μ
Transfacial approaches to the skull base
Development of various crantofacial osteotomies and rigid fixation system allows to approach the skull base with more ease and safety. Transfacial approaches including transzygomatic, transmaxillary and transmandibular approach using osteotmies of the zygoma, Le Fort I, hemimaxillotomy and parasagittal mandibulotomy are descrtbed and discussed.
According to the author's experience including 14 cases, trnaszygomatic approach offers the best technique with wide exposure of middle cranial fossa, infratemporal fossa, pterygoid space, and its combined technique with transmaxillary or transmandibular approach exposes clivus and upper cervical spinc. Trnasmandibular approach exposes the cental base of skull better than transmaxillary approach
with possibility of neck dissection.λ³Έ λ
Όλ¬Έμ 1993λ
λ μμΈλνλ³μ μμμ°κ΅¬λΉμ 보쑰λ₯Ό λ°μ κ²μ
μλ‘μ΄ μΌκ΅΄ μ€μλΆ μ±νμ : ꡬκ°λ΄ Le Fort β ’, β ‘, λ° β 볡ν©κ³¨μ λ¨μ μ κ°λ°
μΌκ΅΄ μ€μλΆ(Midface)λ μν±, μ½λΌ, κ΄λλΌ λΆμλ₯Ό λ§νλ€. μΌκ΅΄ μ€μλΆ ν¨λͺ°μ μν±, μ½λΌ, κ΄λλΌ λΆμμ 골μ λ¨μ μν μ μ§μ μ μν ν¨μΌλ‘μ ν΄κ²°ν μ μλ€.
μ¦ 1) μν±λ§ ν¨λͺ°λ κ²½μ° - Le Fort β
골μ λ¨μ , 2) μν±-μ½λΌ λΆμ ν¨λͺ°μ - Le Fort β
‘, 3) μν±-μ½λΌ-κ΄λλΌ λΆμ ν¨λͺ°μ - Le Fort β
’골μ λ¨μ μ΄ νμνλ€. κ·Έλ¬λ Le Fort β
골μ λ¨μ μ ꡬκ°λ΄λ‘ μννμ§λ§ Le Fort β
‘, β
’골μ λ¨μ μ ꡬκ°λ΄ μ κ°λ§μΌλ‘λ μνμ§ λͺ»νκ³ μμλ€. μ¦ Le Fort β
‘, β
’골μ λ¨μ μ ꡬκ°λ΄ μ κ°λΏ λ§ μλλΌ λ¨Έλ¦¬μ λνΌ μ κ°λ, μΌκ΅΄ μΌλΆ μ¦ μ½λ λ μ£Όμ μ κ°λ₯Ό μΆκ° ν΄μΌλ§ κ°λ₯νλ€. λ°λΌμ μ μλ Le Fort β
‘, β
’골μ λ¨μ ꡬκ°λ΄ μ κ°λ§μΌλ‘ μνν μ μλλ‘ νλ μλ‘μ΄ μ
κ΅μ μ μμ κ°λ°νμκΈ°μ μ΄μ λ³΄κ³ νκ³ μ νλ€. λν μΌκ΅΄ μ€μλΆ ν¨λͺ° μΉλ£μ κ·Όκ°μ μν±, μ½λΌ, κ΄λλΌ λΆμμ 골μ λ¨μΈλ° μ΄λ€ ꡬμ±λΆμκ° λ
립μ μΌλ‘ κ΅μ ν μ μμ΄μΌ μ νν μΌκ΅΄λΌ μ±νμ΄ κ°λ₯νκΈ° λλ¬Έμ ꡬκ°λ΄λ‘ μννλ κ΄λλΌ κ³¨μ λ¨μ μ μμ μλ‘μ΄ κ°λ°νμ¬ νμν λΆμμ λ°λ₯Έ μΌκ΅΄ μ€μλΆμ μ΄μ²΄μ μ±νμμ μ΄ μ
μμΌλ‘λ§ μννμ¬ κ°λ₯νλλ‘ νλ λ³΅ν© μ
κ΅μ μ μμ κ°λ°νμκΈ°μ μ΄μ λ³΄κ³ νκ³ μ νλ€
A experimental study of undemineralized freeze - dried human bone
In order to develop the allogeneic bone implants instead of autogenous bone grafts for maxillofacial reconstruction, undemineralized freeze-dried human bone was processed. The freeze-dried human bone was implanted into the cranial and mandibular defects of the rabbits. The implants were evaluated clinically, roentgenographically and histomophometrically. And immunohistochemical evaluation of the implants was performed on the rat. The results were as follows : 1. When compared with control defects of 0.8Γ0.8cm, the implants on the rabbit defects displayed complete osseous bridging clinically and roentgenographically. Histomophometrically a minimal inflammatory cell infiltrate was present but the defects healed well clinically. 2. When compared with control grafts, the freeze-dried implants on the rat muscle displayed decreased antigenicity by immunohistochemical evaluation, due to freeze-drying process. 3. Undemineralized freeze-dried human bone in this study can be preserved as a bank bone in this study and seems to be applicable for clinical allogeneic bone grafts.1992λ
λ μμΈλνκ΅λ³μ μΌλ° μ°κ΅¬λΉ(026)μ λ³΄μ‘°λ‘ μ΄λ£¨μ΄μ§
MEASUREMENT AND ANALYSIS OF THE RESISTANT MUSCLE FORCE OF MEDIAL PTERYGOID MUSCLE IN THE MANDIBULAR PROGNATHIC PATIENTS
The purpose of this study was to evaluate the resistant force of medial pterygoid muscles against the mandibular advancement and distraction to anterior, and inquire into the relationship between medial pterygoid muscles and cephalometric variables. Sixty six patients with class III malocclusion underwent bilateral sagittal splitting of ramus with intraoralvertico-sagittal ramus osteotomy for mandibular set-back. The spring scale was used to measure the resistance of medial pterygoid muscles after splitting of ramus. Skeletaldental cephalometric analysis was made and statistic package was used for correlation between resistance and cephalometric variables. The resistant force of the right medial pterygoid muscle was greater than the left one in Koreans with class III malocclusion, and the force had a linear regression relationship with facial depth. The results suggested that facial depth has significant correlation with the resistance of medial pterygoid muscle, which can be acquired from patient's cephalometric analysisνκ΅ λ³΄κ±΄λ³΅μ§λΆ μ€μ 곡λμ°κ΅¬μ§μμ¬μ
(00-PJ1-PG1-CH11-0004