Single-molecule Fluorescence Imaging in Living Cells

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Diffusion-Based Single Vesicle Fusion Reveals Homotypic Fusion by the Interactions of t-SNAREs

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Propagation of RNA polymerase copy number variation to downstream protein expression noise in bacterial cells

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Single-vesicle assay for revealing fusion dynamics and the potential toxicity in Parkinson's disease

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만성 뇌졸중 환자에서 선행자세적 조절에 대한 동적 신경근 안정성 훈련과 복부당김 기법의 효과비교

Dept. of Physical Therapy/박사The purpose of this study was to compare the effects of dynamic neuromuscular stabilization (DNS) and abdominal drawing-in maneuver (ADIM) exercises on anticipatory postural adjustment (APA) in individuals with chronic hemiparetic stroke. Twenty-eight adults with chronic hemiparetic stroke (15 males, 13 females; mean age ± standard deviation, 57.7 ± 8.5 years) were enrolled in this study. The subjects were randomly divided into the DNS (n = 14) and ADIM (n = 14) groups. Each of the DNS and ADIM exercises was performed for 30minutes per day, 5 days a week for 4 weeks. The APA was determined by measuring the electromyographic (EMG) onset latency in external oblique (EO), transvers abdominis/internal oblique (TrA/IO), and erector spinae (ES) muscles during rapid shoulder flexion. Paired t-tests were used to compare the EMG onset latency between pre-test and post-test in the respective DNS and ADIM groups. Analysis of covariance (ANCOVA) was used to evaluate the differences between the adjusted means of post-test for the DNS and ADIM intervention groups while controlling for the covariates (pre-test). The level of significance was set at α = 0.05. In the DNS group, paired t-tests revealed significant differences in onset latencies for the EO and TrA/IO muscles between pre-test and post-test. In the ADIM group, paired t-test revealed a significant difference in onset latency for the TrA/IO muscles between pre-test and post-test. A separate ANCOVA showed significant differences in the adjusted mean onset latencies between groups during either the paretic or nonparetic shoulder flexion for the paretic and nonparetic postural trunk muscles (EO, TrA/IO, and ES), with exception of the nonparetic ES muscle during paretic shoulder flexion. Therefore, the results of this study suggest that DNS training was more effective than ADIM training in improving APA via the feedforward activation of postural trunk muscles in individuals with hemiparetic stroke.ope

Single-molecule fluorescence spectroscopy for biological systems

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Probing membrane protein interactions and dynamics by single-particle tracking PALM in living cells

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교환여기 방법에 의한 단일 분자 형광공명 에너지 전달

Thesis(doctoral)--서울대학교 대학원 :화학부 물리화학전공,2005.Docto

The kinetic study of in vitro synaptic vesicle fusion by diffusion-based single vesicle fusion assay

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Revealing the sequential mechanism of synaptic vesicle fusion from the docking to fusion by single-vesicle assay

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