24 research outputs found

    Development of Dry Process Caisson Method for Maintenance of Submerged Harbor Structure

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    Together with the trend of enhancement in domestic industrial development and economic progress due to import and export, the demand for construction of the roads, bridges, especially port facilities, and several coastal protection and ocean structures is increasing rapidly. MOMAF of Korean Government is driving construction of 9 new ports and renovation of the existing fishery ports. Among these structures most of bridge base, wharves, dolphins, quays, and jetties are being newly built of steel or concrete pile. As the base, supporting bulkheads, and piles are underwater after construction, it is difficult to figure out the status of structures and not enough to get maintenance and strengthen the structures. Every year, moreover, these works suck the government budget due to higher incomplete maintenance expense for protection from corrosions of structures and increased underwater construction period. For the purpose of cutting down the government budget, it is necessary to extend the life cycle of the existing structures. We developed a new method for maintenance of submerged structures near the waterline by allowing dry work environment with the floating caisson. The method shows easy to move around the working area and handle. It also showed not only a significant reduction of maintenance expenses and time for anti-corrosion work but also better protection. This will be a milestone to reduce the maintenance and construction expenses for the shore and water structures.제1μž₯ μ„œλ‘  = 1 1.1 μ—°κ΅¬μ˜ λ°°κ²½ = 1 1.2 μ—°κ΅¬μ˜ 동ν–₯ = 5 1.3 μ—°κ΅¬μ˜ λͺ©μ  = 6 1.4 연ꡬ 방법 = 12 제2μž₯ μ—°κ΅¬μ˜ λ°°κ²½ 이둠 = 15 2.1 κ±΄μ‹ν™˜κ²½μ˜ ν•„μš”μ„± = 15 2.2 기쑴의 방식방법 = 21 2.2.1 λΆ€μ‹μ²˜λ¦¬ 방법 = 21 2.2.2 건식 방법 = 27 3μž₯ DPCM의 개발 = 33 3.1 κ°œμš” = 33 3.2 DPCM의 νŠΉμ§• = 35 3.3 DPC의 기초 섀계 = 37 3.4 λͺ¨ν˜• μ œμž‘ 및 μ™Έλ ₯ 계산 = 40 3.4.1 λͺ¨ν˜•μ˜ μ œμž‘ = 40 3.4.2 λͺ¨ν˜•μ˜ μ™Έλ ₯계산 = 43 3.4.3 수리 μ‹€ν—˜ = 50 제4μž₯ DPCM의 μ‹€λ¬Ό μ œμž‘ = 53 4.1 μ‹€μ œλͺ¨ν˜• λΆ€ν’ˆ μ œμž‘ = 53 4.1.1 DPCM μž₯λΉ„μ˜ ꡬ성 = 54 4.1.2 DPCM의 기타μž₯λΉ„ = 63 4.2 DPCM의 ν˜„μž₯ 적용 = 65 4.2.1 λ°©μ‹μž‘μ—…μ˜ 일반적인 μˆœμ„œ = 65 4.2.2 DPCM의 μœ μ˜μ‚¬ν•­ = 67 4.2.3 DPCM μ œμ› = 68 4.2.4 DPCM μž‘μ—…μˆœμ„œ = 69 4.2.5 DPCM의 κΈ°λŒ€νš¨κ³Ό 및 μ‘μš© = 76 제5μž₯ 타 κ³΅λ²•κ³Όμ˜ 비ꡐ 및 뢄석 = 77 5.1 건식곡법 μΈ‘λ©΄ 뢄석 = 77 5.2 뢀식 방지 곡법 μΈ‘λ©΄ 뢄석 = 78 제6μž₯ κ²°λ‘  = 81 μ°Έκ³  λ¬Έν—Œ = 8

    Alteration of Gut Microbiota in Autism Spectrum Disorder: An Overview

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    The microbiota-gut-brain axis, which refers to the bidirectional communication pathway between gut bacteria and the central nervous system, has a profound effect on important brain processes, from the synthesis of neurotransmitters to the modulation of complex behaviors such as sociability and anxiety. Previous studies have revealed that the gut microbiota is potentially related to not only gastrointestinal disturbances, but also social impairment and repetitive behavior-core symptoms of autism spectrum disorder (ASD). Although studies have been conducted to characterize the microbial composition in patients with ASD, the results are heterogeneous. Nevertheless, it is clear that there is a difference in the composition of the gut microbiota between ASD and typically developed individuals, and animal studies have repeatedly suggested that the gut microbiota plays an important role in ASD pathophysiology. This possibility is supported by abnormalities in metabolites produced by the gut microbiota and the association between altered immune responses and the gut microbiota observed in ASD patients. Based on these findings, various attempts have been made to use the microbiota in ASD treatment. The results reported to date suggest that microbiota-based therapies may be effective for ASD, but largescale, well-designed studies are needed to confirm this.ope

    Altered Gut Microbiota in Korean Children with Autism Spectrum Disorders

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    Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social and behavioral impairments. Recent studies have suggested that gut microbiota play a critical role in ASD pathogenesis. Herein, we investigated the fecal microflora of Korean ASD children to determine gut microbiota profiles associated with ASD. Specifically, fecal samples were obtained from 54 children with ASD and 38 age-matched children exhibiting typical development. Systematic bioinformatic analysis revealed that the composition of gut microbiota differed between ASD and typically developing children (TDC). Moreover, the total amounts of short-chain fatty acids, metabolites produced by bacteria, were increased in ASD children. At the phylum level, we found a significant decrease in the relative Bacteroidetes abundance of the ASD group, whereas Actinobacteria abundance was significantly increased. Furthermore, we found significantly lower Bacteroides levels and higher Bifidobacterium levels in the ASD group than in the TDC group at the genus level. Functional analysis of the microbiota in ASD children predicted that several pathways, including genetic information processing and amino acid metabolism, can be associated with ASD pathogenesis. Although more research is needed to determine whether the differences between ASD and TDC are actually related to ASD pathogenesis, these results provide further evidence of altered gut microbiota in children with ASD, possibly providing new perspectives on the diagnosis and therapeutic approaches for ASD patients.ope

    Increasing Trend and Characteristics of Korean Adolescents Presenting to Emergency Department for Self-Harm: A 5-Year Experience, 2015 to 2019

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    Purpose: Emergency department (ED) is a common treatment setting for adolescents with clinically serious self-harm. Here, we investigated the clinical characteristics and trends of adolescents with self-harm who visited the ED in one Korean university hospital. We also compared patients with a single ED visit to those with multiple ED visits to identify the risk factor of repeated visits. Materials and methods: We retrospectively identified patients aged 12 to 18 years who presented to ED for self-harm from January 2015 to December 2019, based on electronic medical records. Self-harm included all thoughts and behaviors indicating intents to harm or hurt oneself, regardless of the degree of such attempt. Results: A total of 168 individuals (male:female=31:137; average 15.99Β±1.64 years) presented to ED following 304 episodes (45 and 259 episodes in males and females, respectively). The number of episodes steeply increased between 2016 and 2019, and the overall number during the study showed an increasing trend (p=0.043). Repeated ED visitors with self-harm showed more history of psychiatric treatment/admission (58.3% vs. 85.4%, p=0.002; 14.2% vs. 43.9%, p<0.001), history of child abuse (32.3% vs. 53.7%, p=0.013), and familial psychiatric history (13.4% vs. 31.7%, p=0.008) compared to those with a single visit. Conclusion: Among Korean adolescents, the number of ED visits and repetition of ED visits for self-harm is on the rise. For adolescents presenting to ED with self-harm, the history of psychiatric treatment/admission, child abuse, and familial psychiatric history should be properly obtained to identify the risk for multiple ED visits.ope

    Reading Landscape of Literary Geography in perspective of New Cultural Geography: The Case Study on γ€ŽMy Sweet City』

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    ν•™μœ„λ…Όλ¬Έ (석사)-- μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› : μ‚¬νšŒκ΅μœ‘κ³Ό(지리전곡), 2017. 2. μ‹ μ •μ—½.문학지리학은 λ‹€μ–‘ν•œ λ¬Έν•™ μž‘ν’ˆ 속에 λ‚΄μž¬ν•΄ μžˆλŠ” 지리적 지식을 μΆ”μΆœν•˜κ³  κ·Έ 의미λ₯Ό 철학적 관점을 ν†΅ν•˜μ—¬ κ΅¬μ²΄ν™”ν•˜λŠ” λ¬Έν™”μ§€λ¦¬ν•™μ˜ ν•œ 뢄야이닀. κ·ΈλŸ¬λ‚˜ 문학지리학은 μ—¬λŸ¬ 내·외적 μš”μΈμœΌλ‘œ μΈν•˜μ—¬ μ§€λ¦¬ν•™μ—μ„œ ν™•κ³ ν•œ 정체성을 ν™•λ¦½ν•˜μ§€ λͺ»ν•˜μ˜€μœΌλ©°, ν˜„μž¬κΉŒμ§€ μ§„ν–‰λ˜μ–΄ 온 μ—¬λŸ¬ μ„ ν–‰ 연ꡬ도 주둜 μž₯μ†Œμ„±κ³Ό μž₯μ†Œμƒμ‹€, κ³΅κ°„μ˜ 이미지 λ“±μ˜ μ£Όμ œμ— ν•œμ •λ˜λŠ” κ²½ν–₯이 μžˆμ—ˆλ‹€. μ΄λŸ¬ν•œ λ¬Έν•™μ§€λ¦¬ν•™μ˜ ν•œκ³„λ₯Ό λ²—μ–΄λ‚˜κΈ° μœ„ν•˜μ—¬ λ³Έ μ—°κ΅¬μ—μ„œλŠ” μ§€λ¦¬ν•™μ˜ 핡심 κ°œλ…μΈ 경관에 μ£Όλͺ©ν•˜κ³  κ΅­λ‚΄ μΉ™λ¦Ώμ†Œμ„€μ˜ λŒ€ν‘œμž‘μœΌλ‘œ 평가받고 μžˆλŠ” μ •μ΄ν˜„μ˜ γ€Žλ‹¬μ½€ν•œ λ‚˜μ˜ λ„μ‹œγ€λ₯Ό μ‹ λ¬Έν™”μ§€λ¦¬μ˜ κ΄€μ μ—μ„œ λ§₯락적 이해에 κ·Όκ±°ν•˜μ—¬ λ…ν•΄ν•˜μ˜€λ‹€. μ§€μ—­μ§€λ¦¬μ˜ 지식, 싀증적이고 ꡬ쑰적인 지리적 λ³€ν™” κ³Όμ • 등을 ꡬ체적으둜 보여 μ€€ 전톡적 관점은 μΈκ°„μ£Όμ˜ 지리학, 포슀트λͺ¨λ˜ 지리학 등을 μ•„μš°λ₯΄λŠ” 신문화지리 κ΄€μ μ˜ λ„μž…μœΌλ‘œ λ¬Έν•™μ§€λ¦¬ν•™μ˜ μƒˆλ‘œμš΄ 지평을 μ—΄μ–΄κ°ˆ 수 μžˆλ‹€. 신문화지리 κ΄€μ μ˜ λ„μž…μ€ κ²½κ΄€μ˜ 독해λ₯Ό ν†΅ν•˜μ—¬ 지리적 κ°€μΉ˜μ˜ 의미λ₯Ό 적절히 ν™˜κΈ°μ‹œν‚€λŠ” 역할을 ν•˜λ©°, λ¬Έν•™ μž‘ν’ˆμ˜ λ§₯락적 이해λ₯Ό κ°€λŠ₯ν•˜κ²Œ ν•œλ‹€. 경관에 λ‚΄μž¬ν•΄ μžˆλŠ” 인간-μ‚¬νšŒ-λ¬Έν™”μ˜ 관계λ₯Ό 총체적으둜 λ…ν•΄ν•˜λŠ” μ‹ λ¬Έν™”μ§€λ¦¬μ˜ 관점은 ν™œλ°œν•œ ν•™μ œ κ°„ 연ꡬλ₯Ό 근거둜 학문적 토양을 λ”μš± ν’λΆ€ν•˜κ²Œ 닀지고 μžˆλ‹€. μ΄λŸ¬ν•œ κ²½ν–₯은 문학지리학이 좔ꡬ해야 ν•  볡합적이고 λ‹€μ–‘ν•œ κ²½κ΄€μ˜ λ…ν•΄μ˜ 과정과도 μžμ—°μŠ€λŸ½κ²Œ 연결될 수 μžˆλŠ” 뢀뢄이닀. μ‹ λ¬Έν™”μ§€λ¦¬μ˜ κ²½κ΄€ μ—°κ΅¬λŠ” μΈλ¬Έκ²½κ΄€μ˜ 싀체λ₯Ό 이둠적으둜 μ •λ¦½ν•œ λ¬Έν™”κ²½κ΄€λ‘ κ³Ό μΈκ°„μ£Όμ˜ μ§€λ¦¬ν•™μ˜ 관점을 λΉ„νŒμ μœΌλ‘œ κ³„μŠΉ λ°œμ „μ‹œμΌ°λ‹€. 경관을 문화적 μ΄λ―Έμ§€λ‘œ μΈμ‹ν•˜κ³  ν™˜κ²½μ„ μž¬ν˜„ν•˜κ³  κ΅¬μ„±ν•˜λ©° μƒμ§•ν™”ν•˜λŠ” νšŒν™”μ  λ°©μ‹μœΌλ‘œ κ²½κ΄€ λ…ν•΄μ˜ μƒˆλ‘œμš΄ μž₯을 μ—΄μ—ˆλ‹€. μ΄λŸ¬ν•œ 독해 방법둠은 λ¬Έν•™Β·νšŒν™”Β·μ‚¬μ§„Β·μ˜ν™” λ“± μž¬ν˜„λœ 맀체에 폭 λ„“κ²Œ μ μš©λ˜μ–΄ κ²½κ΄€μ˜ 내면에 μˆ¨μ–΄ μžˆλŠ” 의미λ₯Ό λ°ν˜€λ‚΄λŠ” λ³΄λŠ” λ°©λ²•μœΌλ‘œ μ΄λ‘ ν™”λ˜μ—ˆλ‹€. μ‹ λ¬Έν™”μ§€λ¦¬μ˜ κ²½κ΄€ 독해 방법은 λ² μΌλ‘œμ„œμ˜ κ²½κ΄€, ν…μŠ€νŠΈλ‘œμ„œμ˜ κ²½κ΄€, μ‘μ‹œλ‘œμ„œμ˜ κ²½κ΄€μ˜ 3κ°€μ§€λ‘œ μœ ν˜•ν™”ν•  수 있으며, 이λ₯Ό 근거둜 γ€Žλ‹¬μ½€ν•œ λ‚˜μ˜ λ„μ‹œγ€μ— λ‚˜νƒ€λ‚˜λŠ” λ‹€μ–‘ν•œ λ„μ‹œκ²½κ΄€μ„ μ—¬μ„±μ˜ κ΄€μ μ—μ„œ 독해할 수 μžˆλ‹€. μ„œμšΈμ΄λΌλŠ” 곡간적 λ°°κ²½κ³Ό 2005λ…„λΆ€ν„° 2006λ…„ 6μ›” 5μΌκΉŒμ§€μ˜ μ‹œκ°„μ  배경을 따라 μ „κ°œλ˜λŠ” γ€Žλ‹¬μ½€ν•œ λ‚˜μ˜ λ„μ‹œγ€λŠ” 결혼, 계급, κ°œμΈμ‚¬, μ†ŒλΉ„λΌλŠ” μ£Όμš” 경관이 주인곡의 μ‹œμ (μ‹œμ„ )μ—μ„œ μžμ„Έν•˜κ²Œ λ¬˜μ‚¬λ˜κ³  μžˆλ‹€. λ„μ‹œμ˜ λ‹€μ–‘ν•œ 경관은 μ—¬μ„±μ—κ²Œ 인간-μ‚¬νšŒ-λ¬Έν™”κ°€ μ’…ν•©μ μœΌλ‘œ μ–΄μš°λŸ¬μ§„ ν˜•μ‹μœΌλ‘œ μΈμ‹λœλ‹€. μ΄λŸ¬ν•œ 인식은 μ΄λ°μ˜¬λ‘œκΈ°μ™€ μ‚¬νšŒμ  λ³€ν™”κ°€ λ‚΄μž¬ν•΄ μžˆλŠ” 지리적 κ°€μΉ˜μ— κ·Όκ±°ν•˜λ©°, μž‘ν’ˆ μ†μ—μ„œ μ‚¬λ¬Όν™”λœ ν˜•νƒœμ™€ ν–‰λ™ν™”λœ μ–‘μ‹μœΌλ‘œ κ΅¬μ²΄ν™”λ˜μ–΄ λ‚˜νƒ€λ‚œλ‹€. 기쑴의 μ‚¬νšŒμ§ˆμ„œμ— λŒ€ν•œ μžμ—°μŠ€λŸ¬μš΄ μˆœμ‘κ³Ό ν™œμš©μ΄ λ“œλŸ¬λ‚˜λŠ” ν¬μŠ€νŠΈνŽ˜λ―Έλ‹ˆμ¦˜μ˜ κ²½κ΄€, λŒ€λ„μ‹œλΌλ©΄ μ–΄λ””μ—μ„œλ‚˜ λ‚˜νƒ€λ‚  수 μžˆλŠ” 무μž₯μ†Œμ„±μ˜ κ²½κ΄€, μžμ‹ μ„ μœ„λ‘œν•˜κ³  λ§Œμ‘±ν•˜κ²Œ ν•˜λŠ” λ³΄μƒμ˜ 경관을 λ‘λ“œλŸ¬μ§„ νŠΉμ§•μœΌλ‘œ 정리할 수 μžˆλ‹€. λ¬Έν•™μ§€λ¦¬ν•™μ˜ 정체성 확보와 ν’λΆ€ν•œ 연ꡬ 결과의 λ„μΆœμ€ 신문화지리 κ΄€μ μ˜ λ„μž…μœΌλ‘œ κ°€λŠ₯성을 높일 수 μžˆλ‹€. 신문화지리 κ΄€μ μ˜ λ„μž…μ€ λ¬Έν•™μ§€λ¦¬ν•™μ˜ λ‹€μ–‘ν•œ 주제λ₯Ό 인간-μ‚¬νšŒ-λ¬Έν™”μ˜ 총체적 관점을 ν†΅ν•˜μ—¬ 연ꡬ할 수 있게 ν•œλ‹€. λ³Έ μ—°κ΅¬μ—μ„œλŠ” μ§€λ¦¬ν•™μ˜ 핡심 κ°œλ…μΈ 경관에 μ£Όλͺ©ν•˜μ—¬ λ¬Έν•™μ§€λ¦¬ν•™μ˜ 지평을 λ„“ν˜€ 보렀 ν•˜μ˜€λ‹€. μ΄λŸ¬ν•œ μ‹œλ„κ°€ μƒˆλ‘œμš΄ 좜발점이 λ˜μ–΄ 문학지리학 연ꡬ가 λ”μš± λ³Έκ²©ν™”λ˜κ³  λ‹€μ–‘ν™”ν•˜κΈ°λ₯Ό κΈ°λŒ€ν•œλ‹€.β… . μ„œ λ‘  1 1. 연ꡬ배경 및 연ꡬλͺ©μ  1 2. μ—°κ΅¬λŒ€μƒ 및 연ꡬ방법 4 3. λ…Όλ¬Έμ˜ ꡬ성 6 β…‘. 이둠적 λ°°κ²½ 8 1. λ¬Έν•™μ§€λ¦¬ν•™μ—μ„œμ˜ κ²½κ΄€ 8 1) 전톡적 관점 8 2) 신문화지리 관점 11 2. μ‹ λ¬Έν™”μ§€λ¦¬μ˜ κ²½κ΄€ 독해 16 1) κ²½κ΄€ λ…ν•΄μ˜ νŠΉμ„±κ³Ό 방법둠 16 2) 3가지 μœ ν˜•μ˜ 독해 방법둠 26 3. μ†Œ κ²° 32 β…’.γ€Žλ‹¬μ½€ν•œ λ‚˜μ˜ λ„μ‹œγ€μ˜ νŠΉμ„±κ³Ό κ²½κ΄€ 독해 ν”„λ ˆμž„ 34 1.γ€Žλ‹¬μ½€ν•œ λ‚˜μ˜ λ„μ‹œγ€μ˜ νŠΉμ„±κ³Ό 평가 34 2. κ²½κ΄€ 독해 ν”„λ ˆμž„ 42 β…£.γ€Žλ‹¬μ½€ν•œ λ‚˜μ˜ λ„μ‹œγ€μ˜ κ²½κ΄€ 독해 47 1. 베일(veil): 결혼의 κ²½κ΄€ 47 2. 베일(veil): κ³„κΈ‰μ˜ κ²½κ΄€ 54 3. ν…μŠ€νŠΈ(text): κ°œμΈμ‚¬μ˜ κ²½κ΄€ 58 4. μ‘μ‹œ(gaze): μ†ŒλΉ„μ˜ κ²½κ΄€ 66 β…€. κ²° λ‘  73 μ°Έκ³ λ¬Έν—Œ 78 Abstract 86Maste

    Polymorphisms of homocysteine metabolism in Korean amyotrophic lateral sclerosis patients

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    Thesis(master`s)--μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› :μ˜ν•™κ³Ό λ‡Œμ‹ κ²½κ³Όν•™μ „κ³΅,2006.Maste

    Nishina Yoshio and the modern physics in Japan

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    ν•™μœ„λ…Όλ¬Έ(박사)--μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› :ν˜‘λ™κ³Όμ • 과학사 및 κ³Όν•™μ² ν•™ 과학사전곡,1999.Docto

    κ³΅μ‹œμ§€κ°€μ˜ 문제점과 κ°œμ„ λ°©μ•ˆ

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    λ…ΈνŠΈ : 이 λ³΄κ³ μ„œλŠ” κ΅­ν† κ°œλ°œμ—°κ΅¬μ›μ˜ μžμ²΄μ—°κ΅¬λ¬Όλ‘œμ„œ μ •λΆ€μ˜ μ •μ±…μ΄λ‚˜ κ²¬ν•΄μ™€λŠ” μƒκ΄€μ—†μŒμ„ λ°ν˜€λ‘λŠ” λ°”μž…λ‹ˆλ‹€

    Low working memory capacity in euthymic bipolar I disorder: No relation to reappraisal on emotion regulation

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    BACKGROUND: Emotion regulation (ER) applies behavioral and cognitive strategies to modify the appearance and intensity of emotions. Working memory capacity (WMC) plays an important role in the ER process, particularly through its influence on the efficiency of ER strategies. METHODS: We investigated interactions between WMC and three ER strategies, namely cognitive reappraisal, expressive suppression, and rumination, in 43 euthymic patients with bipolar I disorder and 48 healthy control subjects. We used the Korean versions of the Operation Span Task, Emotion Regulation Questionnaire, Ruminative Response Scale, and Difficulties in Emotion Regulation Scale. RESULTS: WMC modulated the efficacy of cognitive reappraisal in healthy controls with high WMC, but not in patients with bipolar disorder. There were no significant interactions between WMC and expressive suppression or rumination in either group. LIMITATIONS: These include the small sample size, use of neutral words to evaluate negative emotion, use of self-administered questionnaires, and relatively high cut-off for the definition of euthymic states. A number of uncontrolled factors may have influenced our results including patients' duration of remission, number of episodes, psychiatric family history, and current psychiatric medications. CONCLUSIONS: Our findings suggest that working memory does not function effectively in the reappraisal process during ER in patients with bipolar disorder. This may indicate that top-down regulation of emotion is impaired in bipolar disorder. Cognitive interventions aimed at improving ER in such patients may be ineffective.restrictio
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