Double burden of malnutrition: implication in nutrition support on the North Korean children

본 연구는 영양상태에 따른 성장결과가 생애후반기 건강에 미치는 영향을 이해하여 어린이들의 건강 성장을 지지하는 영양지원 방안을 모색하기 위해 수행되었다. 영양불량의 이중부담 현상이 전 세계적으로 나타나고 있다. 이는 영양부족과 영양과잉 문제가 공존하는 양상을 표현하는 것으로 영양불량이 만연한 개발도상국에서 경제수준 향상과 함께 비만 및 영양 관련 비전염성 만성질병이 유행하게 됨으로써 나타나는 것으로 보고 있다. 또한, 생애초기 영양부족이 이러한 영양관련 만성질병에 대한 감수성을 높인다는 연구결과들이 많다. 북한 어린이의 심각한 영양부족에 대해서는 이미 잘 알려져 있다. 이러한 극심한 영양부족 상태는 통일 후 영양환경 개선에 따라 영양불량의 이중부담 문제로 전환될 수 있다. 관례적으로 영양지원이라 하면 영양부족상태를 해소하기 위한 것으로 이해되어 왔으나, 영양불량의 이중부담 상황에서는 영양부족 뿐 아니라 영양과잉 문제로 인식되는 비만 및 관련 질환 모두에 대한 대응이 요구된다. 그러나 만성질병 문제도 실은 만성적인 영양불량에서 시작될 수 있기 때문에 궁극적으로는 다양성이 확보된 충분한 식사와 같은 하나의 이상적인 식사유형의 확립이 요구된다. 장기적으로 건강한 식품에 대한 접근성을 높이는 구조적 기반을 확립하는 정책적 노력과 함께 생애초기 건강한 성장을 지지하는 질적인 영양지원 방안의 모색이 필요하다.This study was performed to investigate nutrition support plan for childs healthy growth reviewing the accumulated evidence about child's growth and health in later life. The emergence of a double burden of malnutrition is observed at global level. The phenomenon represents simultaneous occurrence of under- and overnutrition. This may be resulted from obesity and nutrition-related non-communicable diseases becoming prevalent as economic status improves in the developing countries with high rate of undernutrition. In addition, there is a growing evidence that undernutrition in early life may predispose the population to be more susceptible to nutrition-related non-communicable diseases. Severe undernutrition in the north Korea is well recognized. There is a concern about double burden of malnutrition in the future population in the unified Korea. Historically nutrition program has addressed typical undernutrition. However current double burden situation calls on attention to both under- and nutrition-related non-communicable diseases for the nutrition action plans and strategies. As large portion of nutrition-related non-communicable diseases could be originated from chronic malnutrition, one unified approach (i.e. such as adequate diverse healthy diet) to solve both of the problem could be applied. Nutrition policy should focus on the construction of infrastructure to improve accessibility to healthy food and development of nutrition support program for healthy growth in early life.이 연구는 서울대 통일평화연구원 2011년 통일학·평화학 연구기금으로 수행되었음

Analysis of dietary intake and development of balanced diet index among different age groups in Korea

학위논문(박사)--서울대학교 대학원 :식품영양학과,2000.Docto

고등학교 불어교육에 있어서 신체언어 교육의 필요성과 그 방안

학위논문(석사)--서울대학교 대학원 :외국어교육과 불어교육전공,1996.Maste

한국인 GNE근병증 환자들의 임상양상과 유전학적 분석

Dept. of Medicine/석사Background Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (GNE) myopathy is an autosomal recessive neuromuscular disorder characterized by early adult-onset weakness of the distal muscles of the lower limbs. The clinical spectrum of GNE myopathy varies and it is not clear how the same GNE gene mutations can result in different phenotypes. Here, we present the clinical, pathological and genetic characteristics of twenty-one Korean patients with GNE myopathy.Methods Twenty-one GNE myopathy patients were included in this study, conducted from 2004 to 2011. Based on medical records, including the patients’ sex, onset age, family history, clinical history, serum CK level, neurologic examination, findings of muscle biopsy, muscle imaging findings and electrophysiologic features were extensively reviewed. Mutation of the GNE gene (9p13.3) was confirmed by DNA direct sequencing analysis in all patients.Results The mean onset age was 23.8 ± 8.8 years (mean ± s.d.). Patient serum CK levels were slightly to moderately elevated, ranging from 41 to 2610 IU. Among all patients, twelve patients were female and nine patients were male. Except for eight patients, all of the patients presented with only distal muscle weakness in the lower extremities initially. The most common mutation was V572L, followed by C13S.Conclusions The clinical manifestations of our patients with GNE mutations varied. Among twenty-one patients, thirteen patients showed the typical GNE myopathy phenotype. Our data showed that there was no relationship between clinical features and site of mutation. Therefore, we suggest that neither homozygous nor compound heterozygous models are correlated with disease phenotype or disease severity.ope

당뇨병 환자군과 대조군의 vitamin C 영양 상태평가 및 혈청 ascorbic acid 수준에 영향을 미치는 요인 분석

학위논문(석사)--서울大學校 大學院 :食品營養學科,1996.Maste

Trends in the major dish groups and food groups contributing to sodium intake in the Korea National Health and Nutrition Examination Survey 1998-2010

The purpose of this study was to evaluate trends in the sources of dietary sodium intake in a representative Korean population in the Korea National Health and Nutrition Examination Survey (KNHANES) conducted in 1998, 2001, 2005, 2007, 2008, 2009, and 2010. The study consisted of 53,570 men and women aged 7 years or older participating in the KNHANES during the corresponding years. Overall sodium intake and the mean percent contribution of each dish and food group to dietary sodium intake across 1998-2010 were calculated. The means of sodium intake ranged between 4,572.6-5,498.9 mg/d across 1998-2010. The major dish groups contributing to dietary sodium intake were kimchi (1,154.8-1,521.2 mg/d), noodles and dumplings (505.3-760.5 mg/d), soups (465.3-714.8 mg/d), and stews and casseroles (387.0-579.8 mg/d). The combined mean percent contribution from the top four dish groups contributing to dietary sodium intake showed a slight decrease over the period; 64.4% in 1998, 64.5% in 2001, 59.3% in 2005, 58.2% in 2007, 56.3% in 2008, 56.7% in 2009, and 54.4% in 2010. The major food groups contributing to dietary sodium intake were seasonings (1,852.9-2,435.9 mg/d), vegetables (1,425.6-1,792.1 mg/d), grains (482.2-778.1 mg/d), and fish and shellfish (257.2-351.4 mg/d). In addition, the combined mean percent contribution from the top four food groups showed a slight decrease over the period; 92.8% in 1998, 93.2% in 2001, 93.8% in 2005, 92.1% in 2007, 91.7% in 2008, 90.9% in 2009, and 90.7% in 2010. In summary, we did not observe a reduction in dietary sodium intake over time, however, the percent contributions from the top major dish groups or food groups to dietary sodium intake showed a decrease over the last decade. (Korean J Nutr 2013; 46(1): 72 ∼ 82). © 2013 The Korean Nutrition Society.N