Park EunSeok

학위논문(석사)아주대학교 일반대학원 :분자과학기술학과,2012. 2Maste

Hermeneutical practice : interpretation and creation of Lu Xuns Gu shi xin bian

학위논문(석사)--서울대학교 대학원 :중어중문학과 문학전공,2007.Maste

現代中國語 命令文 硏究 : 主語와 呼格語를 중심으로

학위논문(석사)--서울대학교 대학원 :중어중문학과 어학전공,2002.Maste

A Review on the Role of Stereotactic Radiosurgery for Pineal Tumors

Pineal region tumors, although rare, consist of variable histological entities including germ cell tumors most frequently, followed by pineal parenchymal tumors, gliomas, and other miscellaneous tumors. As different therapeutic strategies are required according to the histological diagnosis, correct tissue diagnosis is essential to provide optimal therapy. Treatment options include surgery, radiation in the form of either fractionated radiotherapy or stereotactic radiosurgery, and chemotherapy. Complete surgical resection can provide a chance of cure for a certain kind of benign tumors such as pineocytomas, although it is not always feasible and the risks of morbidity and mortality should be carefully balanced. For malignant tumors such as germ cell tumors or pineoblastomas, multimodal approaches combining surgery, radiotherapy, and chemotherapy are usually adopted. Stereotactic radiosurgery constitutes one of the viable armamentaria in the treatment of tumors arising in this critical location. It can be used as a primary, adjunct or boost, or salvage treatment, depending on specific tumor types as well as clinical situations

Single- and hypofractionated stereotactic radiosurgery for large (> 2 cm) brain metastases: a systematic review

Purpose Since frameless stereotactic radiosurgery (SRS) techniques have been recently introduced, hypofractionated SRS (HF-SRS) for large brain metastases (BMs) is gradually increasing. To verify the efficacy and safety of HF-SRS for large BMs, we aimed to perform a systematic review and compared them with SF-SRS. Methods We systematically searched the studies regarding SF-SRS or HF-SRS for large (> 2 cm) BM from databases including PubMed, Embase, and the Cochrane Library on July 31, 2018. Biologically effective dose with the alpha/beta ratio of 10 (BED10), 1-year local control (LC), and radiation necrosis (RN) were compared between the two groups, with the studies being weighted by the sample size. Results The 15 studies with 1049 BMs that described 1-year LC and RN were included. HF-SRS tended to be performed in larger tumors; however, higher mean BED10 (50.1 Gy(10) versus 40.4 Gy(10), p < 0.0001) was delivered in the HF-SRS group, which led to significantly improved 1-year LC (81.6 versus 69.0%, p < 0.0001) and 1-year overall survival (55.1 versus 47.2%, p < 0.0001) in the HF-SRS group compared to the SF-SRS group. In contrast, the incidence of radiation toxicity was significantly decreased in the HF-SRS group compared to the SF-SRS group (8.0 versus 15.6%, p < 0.0001). Conclusion HF-SRS results in better LC of large BMs while simultaneously reducing RN compared to SF-SRS. Thus, HF-SRS should be considered a priority for SF-SRS in patients with large BMs who are not suitable to undergo surgical resection

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Cavernous sinus dural arteriovenous fistulas (CSDAVFs) are arteriovenous shunts between small dural branches arising from the external and/or internal carotid arteries and the cavernous sinus (CS). And now a days, endovascular treatment is the treatment of choice in CSDAVF. We review the anatomy and classifications of CSDAVFs, discussing and detailing these considerations in the treatment of CSDAVFs, theroretically and the light of recent literatures