71 research outputs found

    ์›๊ฒฉํƒ์‚ฌ ๋ฐ GIS ๊ธฐ๋ฒ•์„ ์ด์šฉํ•œ ์ง€ํ‘œํ™˜๊ฒฝ ๋ถ„์„ ์—ฐ๊ตฌ : ํ•˜๋‚จ์ง€์—ญ์˜ ์‘์šฉ์‚ฌ๋ก€

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    ํ•™์œ„๋…ผ๋ฌธ(์„์‚ฌ)--์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› :๊ณผํ•™๊ต์œก๊ณผ ์ง€๊ตฌ๊ณผํ•™์ „๊ณต,1997.Maste

    ํ˜„๋Œ€ ํ•œ๊ตญ์–ด '-๋ฅผ' ์ค‘์ถœ๋ฌธ์˜ ์˜๋ฏธ์™€ ํ†ต์‚ฌ ์—ฐ๊ตฌ

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    ํ•™์œ„๋…ผ๋ฌธ (์„์‚ฌ)-- ์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› : ๊ตญ์–ด๊ตญ๋ฌธํ•™๊ณผ, 2014. 8. ์ „์˜์ฒ .๊ธฐ์กด โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ ํ˜น์€ โ€˜-๋ฅผโ€™๊ณผ ๊ด€๋ จํ•œ ๋…ผ์˜๋“ค์„ ์‚ดํŽด๋ณด๋ฉด, โ€˜-๋ฅผโ€™์˜ ํ†ต์‚ฌ์  ๊ธฐ๋Šฅ๊ณผ ์˜๋ฏธยทํ™”์šฉ์  ๊ธฐ๋Šฅ์„ ๊ตฌ๋ถ„ํ•˜์ง€ ์•Š์€ ์ฑ„ ๊ฒฉ์กฐ์‚ฌ โ€˜-๋ฅผโ€™๊ณผ ๋ณด์กฐ์‚ฌ โ€˜-๋ฅผโ€™์˜ ํŒฝํŒฝํ•œ ์ค„๋‹ค๋ฆฌ๊ธฐ๊ฐ€ ์ด์–ด์ ธ ์™”๋‹ค. ๋˜ํ•œ ํ†ต์‚ฌ ์ธต์œ„์™€ ๋‹ดํ™” ์ธต์œ„์˜ ๊ตฌ๋ถ„์ด ํ•„์š”ํ•˜๋‹ค๋Š” ๊ฒƒ์„ ์•Œ๋ฉด์„œ๋„ ๋‘ ์ธต์œ„ ๊ฐ„์— ์—ฐ๊ด€์„ฑ์„ ๊ณ ์ฐฐํ•˜๋Š” ๋…ผ์˜๋กœ๊นŒ์ง€๋Š” ์ด์–ด์ง€์ง€ ๋ชปํ•˜์˜€๋‹ค. ๋ณธ๊ณ ๋Š” โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์˜ ์˜๋ฏธยทํ†ต์‚ฌ์  ํŠน์ง•์„ ์‚ดํŽด๋ด„์œผ๋กœ์จ ํ†ต์‚ฌ ์ธต์œ„์—์„œ ๊ฒฉ์กฐ์‚ฌ โ€˜-๋ฅผโ€™์˜ ๊ธฐ๋Šฅ๊ณผ ๋‹ดํ™” ์ธต์œ„์—์„œ ์ดˆ์  ํ‘œ์ง€ โ€˜-๋ฅผโ€™์˜ ๊ธฐ๋Šฅ ๊ฐ„์˜ ์ƒ๊ด€๊ด€๊ณ„๋ฅผ ๋ฐํžˆ๊ณ  ๊ทธ ์—ญํ• ์„ ์ •๋ฆฝํ•˜๊ณ ์ž ํ•˜์˜€๋‹ค. ์ด๋ฅผ ์œ„ํ•ด ๊ธฐ์กด์— ๋‚˜์—ด์‹์œผ๋กœ ์„ค๋ช…๋œ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์„ โ€˜-๋ฅผโ€™์˜ ์„ฑ๊ฒฉ์— ๋”ฐ๋ผ ์ฒด๊ณ„์ ์œผ๋กœ ์œ ํ˜•ํ™”ํ•˜๊ณ  ๊ทธ ์ •๋ณด ๊ตฌ์กฐ๋ฅผ ๋ถ„์„ํ•˜์˜€๋‹ค. ๋ณธ๊ณ ์˜ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์€ ํ˜•ํƒœ์ ์œผ๋กœ๋Š” โ€˜-๋ฅผโ€™์ด ๋‘ ๋ฒˆ ์ถœํ˜„ํ•œ ๊ตฌ๋ฌธ์ด๋ฉฐ, ํ†ต์‚ฌ์ ์œผ๋กœ๋Š” ๋‹จ๋ฌธ์˜ ํƒ€๋™์‚ฌ ๊ตฌ๋ฌธ์ด๋‹ค. ๊ทธ๋ฆฌ๊ณ  ์˜๋ฏธ์ ์œผ๋กœ๋Š” ๋น„์ค‘์ถœ๋ฌธ๊ณผ ๋น„๊ตํ•˜์—ฌ ์˜๋ฏธ์  ํ˜„์ €์„ฑ์„ ๋“œ๋Ÿฌ๋‚ด๋Š” ๊ตฌ๋ฌธ์ด๋‹ค. ์ด๋Ÿฌํ•œ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์—์„œ โ€˜-๋ฅผโ€™์€ ๋น„๋ก ๊ทธ ํ˜•ํƒœ๋Š” ๊ฐ™์ง€๋งŒ ๊ฒฐํ•ฉํ•˜๋Š” ๋Œ€์ƒ ๋ฐ ๋ถ„ํฌ์— ๋”ฐ๋ผ ๊ทธ ๊ธฐ๋Šฅ๊ณผ ์˜๋ฏธ๊ฐ€ ๋‹ฌ๋ž๋‹ค. ์ด์— ๋”ฐ๋ผ ๋ณธ๊ณ ๋Š” โ€˜-๋ฅผโ€™์˜ ์„ฑ๊ฒฉ์„ ๊ธฐ์ค€์œผ๋กœ ํ•˜์—ฌ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์„ ํฌ๊ฒŒ ๋ฌดํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ๊ณผ ์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์œผ๋กœ ๋‚˜๋ˆ„์—ˆ๋‹ค. ๊ทธ๋ฆฌ๊ณ  ์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์€ ๋‹ค์‹œ ํ˜•ํƒœ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ๊ณผ ๋ถ„ํฌ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์œผ๋กœ ๋‚˜๋ˆ„์—ˆ๋‹ค. ๋ฌดํ‘œ์  โ€˜-๋ฅผโ€™์€ ์ „ํ˜•์ ์ธ ๋Œ€๊ฒฉ์กฐ์‚ฌ โ€˜-๋ฅผโ€™์ด๋ฉฐ, ์œ ํ‘œ์  โ€˜-๋ฅผโ€™์€ ๋น„๋Œ€๊ฒฉ์ด๋‚˜ ๋น„๋…ผํ•ญ์— ๊ฒฐํ•ฉํ•˜์—ฌ ๋น„์ „ํ˜•์ ์ธ ์“ฐ์ž„์„ ๋ณด์ด๋Š” โ€˜-๋ฅผโ€™์ด๋‹ค. ํ˜•ํƒœ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์€ ๋‹ค๋ฅธ ๋” ์ ํ•ฉํ•œ ์กฐ์‚ฌ๋กœ ๊ต์ฒด๋  ์ˆ˜ ์žˆ๋Š” โ€˜-๋ฅผโ€™์ด๋ฉฐ, ๋ถ„ํฌ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™์€ ๊ฒฉ์กฐ์‚ฌ๊ฐ€ ์ „ํ˜€ ํ•„์š”ํ•˜์ง€ ์•Š์€ ์ž๋ฆฌ์— ์“ฐ์ธ โ€˜-๋ฅผโ€™์ด๋‹ค. ๊ฐ ์œ ํ˜•์˜ ์ •๋ณด ๊ตฌ์กฐ๋ฅผ ๋ถ„์„ํ•œ ๊ฒฐ๊ณผ, ๋ฌดํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์€ ํ•˜์˜ ๊ด€๊ณ„ใ€€์œ ํ˜•์„ ์ œ์™ธํ•˜๋ฉด โ€˜-๋ฅผโ€™์ด ๊ฒฐํ•ฉํ•œ ๋‘ ๋…ผํ•ญ ๊ฐ„์— ํ™”์ œ-์ดˆ์ , ์ดˆ์ -ํ™”์ œ์˜ ์ •๋ณด ๊ตฌ์กฐ๊ฐ€ ๋ชจ๋‘ ๊ฐ€๋Šฅํ•˜์˜€๋‹ค. ์ด๊ฒƒ์€ โ€˜-๋ฅผโ€™์ด ํ†ต์‚ฌ ์ธต์œ„์—์„œ๋Š” ๊ฒฉ ํ‘œ์ง€ ๊ธฐ๋Šฅ์„ ํ•˜์ง€๋งŒ, ๋‹ดํ™” ์ธต์œ„์—์„œ๋Š” ๋งฅ๋ฝ์— ๋”ฐ๋ผ ์ดˆ์  ์˜๋ฏธ๋ฅผ ์‹คํ˜„ํ•  ์ˆ˜ ์žˆ์Œ์„ ๋ณด์—ฌ์ฃผ๋Š” ๊ฒƒ์ด๋ผ๊ณ  ํ•  ์ˆ˜ ์žˆ๋‹ค. ๋˜ํ•œ ๊ฒฉ์กฐ์‚ฌ โ€˜-๋ฅผโ€™์ด ์œ ํ‘œ์ ์œผ๋กœ ์“ฐ์ผ์ˆ˜๋ก ๋‹ดํ™” ์ธต์œ„์—์„œ โ€˜-๋ฅผโ€™์ด ๊ฐ–๊ณ  ์žˆ๋˜ ์ดˆ์  ์˜๋ฏธ๊ฐ€ ํ†ต์‚ฌ ์ธต์œ„์—์„œ ๋ถ€๊ฐ๋˜๋Š” ๊ฒฝํ–ฅ์„ฑ์„ ํŒŒ์•…ํ•ด๋ณผ ์ˆ˜ ์žˆ์—ˆ๋‹ค. ์ฆ‰ ๋ฌดํ‘œ์  โ€˜-๋ฅผโ€™, ํ˜•ํƒœ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™, ๋ถ„ํฌ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™๋กœ ๊ฐˆ์ˆ˜๋ก ํ†ต์‚ฌ ์ธต์œ„์—์„œ โ€˜-๋ฅผโ€™์˜ ์ดˆ์  ์˜๋ฏธ๊ฐ€ ํ˜„์ €ํ•ด ์ง€๋Š” ๊ฒƒ์„ ์•Œ ์ˆ˜ ์žˆ์—ˆ๋‹ค. ๋‚˜์•„๊ฐ€ ๋ถ„ํฌ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™์€ ๋‹ดํ™” ์ธต์œ„์—์„œ โ€˜-๋ฅผโ€™์˜ ์ดˆ์  ์˜๋ฏธ๊ฐ€ ํ†ต์‚ฌ ์ธต์œ„์—์„œ โ€˜๊ฐ•์กฐโ€™ ์˜๋ฏธ๋กœ ๋ฌธ๋ฒ•ํ™”ํ•œ ๊ฒƒ์œผ๋กœ ์ดํ•ดํ•  ์ˆ˜ ์žˆ์—ˆ๋‹ค.1. ์„œ๋ก  1 1.1. ์—ฐ๊ตฌ ๋Œ€์ƒ ๋ฐ ๋ชฉ์  1 1.2. ์„ ํ–‰ ์—ฐ๊ตฌ 3 1.3. ๋…ผ์˜์˜ ๊ตฌ์„ฑ 7 2. ๊ธฐ๋ณธ์  ๋…ผ์˜ 9 2.1. ๊ฒฉ์กฐ์‚ฌ, ๋ณด์กฐ์‚ฌ์˜ โ€˜-๋ฅผโ€™ 9 2.2. ์ดˆ์ , ํ™”์ œ์˜ โ€˜-๋ฅผโ€™ 16 2.2.1. ์ดˆ์ ๊ณผ ํ™”์ œ 17 2.2.2. ํ™•์ธ ์ดˆ์ ๊ณผ ์ •๋ณด ์ดˆ์  24 3. โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์˜ ์œ ํ˜• 34 3.1. โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ์˜ ํ˜•์„ฑ ์กฐ๊ฑด 34 3.2. ๋ฌดํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 39 3.3. ์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 44 3.3.1. ํ˜•ํƒœ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 44 3.3.2. ๋ถ„ํฌ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 47 3.4. ์†Œ๊ฒฐ 52 4. ๋ฌดํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 54 4.1. ๋ถ€๋ถ„ ๊ด€๊ณ„ ์ค‘์ถœ๋ฌธ 54 4.2. ์ˆ˜๋Ÿ‰ ๊ด€๊ณ„ ์ค‘์ถœ๋ฌธ 61 4.3. ํ•˜์˜ ๊ด€๊ณ„ ์ค‘์ถœ๋ฌธ 67 4.4. ์†Œ๊ฒฐ 72 5. ์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 74 5.1. ํ˜•ํƒœ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 74 5.1.1. ์ฒ˜๊ฒฉ ๋…ผํ•ญ์— ๊ฒฐํ•ฉํ•œ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 74 5.1.2. ์—ฌ๊ฒฉ ๋…ผํ•ญ์— ๊ฒฐํ•ฉํ•œ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 79 5.1.3. ํ–ฅ๊ฒฉ ๋…ผํ•ญ์— ๊ฒฐํ•ฉํ•œ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 83 5.2. ๋ถ„ํฌ-์œ ํ‘œ์  โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 87 5.2.1. ์–ด๊ธฐ์— ๊ฒฐํ•ฉํ•œ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 88 5.2.2. ์–ด๋ฏธ์— ๊ฒฐํ•ฉํ•œ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 92 5.2.3. ๋ถ€์‚ฌ(์–ด)์— ๊ฒฐํ•ฉํ•œ โ€˜-๋ฅผโ€™ ์ค‘์ถœ๋ฌธ 95 5.3. ์†Œ๊ฒฐ 100 6. ๊ฒฐ๋ก  102 ์ฐธ๊ณ ๋ฌธํ—Œ 105<ABSTRACT> 114Maste

    The Role of RNA-binding Factor in IRES-dependent Translation

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    DoctorEukaryotic cells have many strategies to control the translation of mRNA for the synthesis of protein. Beyond the canonical cap-dependent model of cap recognition followed by ribosomal scanning, an alternative method of cap-independent translation was first described for the picornavirus family and subsequently for a growing subset of viral and cellular mRNAs. Translation of many cellular and viral mRNAs is directed by internal ribosomal entry sites (IRESs). Several proteins that enhance IRES activity through interactions with IRES elements have been discovered. However, the molecular basis for the IRES-activating function of the IRES-binding proteins remains unknown. Here, I report that NS1-associated protein 1 (NSAP1), which augments several cellular and viral IRES activities, enhances hepatitis C viral (HCV) IRES function by facilitating the formation of translation-competent 48S ribosome-mRNA complex. NSAP1, which is associated with the solvent side of the 40S ribosomal subunit, enhances 80S complex formation through correct positioning of HCV mRNA on the 40S ribosomal subunit. NSAP1 seems to accomplish this positioning function by directly binding to both a specific site in the mRNA downstream of the initiation codon and a 40S ribosomal protein (or proteins). Cellular IRES have pivotal role modulating protein synthesis in several stress condition that cap-dependent translation is inhibited. However, unlike viral IRES, basic module to be required for IRES activity in cellular IRES is fully unknown and to find such a module is challenging task. Here, I provide the evidence that ACR, an A rich sequence originated from HCV IRES, can function as artificial IRES in vitro and in vivo. The efficiency of ACR-driven translation is proportional to the number of ACR in reporters, and A to G substitution impaired ACR-dependent translation enhancement. NF45 is identified as ACR interacting protein and ACR-dependent translation was decreased in NF45 knockdown cells. These data indicate that ACR is one of the basic modules of cellular IRES modulated by NF45. In summary, I investigated molecular basis of RNA-binding protein in IRES-dependent translation of eukaryotic mRNAs. Especially, I showed that NSAP1 enhances HCV IRES-dependent translation by facilitating the formation of a translation-competent 48S complex that is ready to form the 80S complex through association of with the HCV IRES and 40S ribosomal subunit. This is the first report showing that a protein that interacts with an IRES element enhances translation through a direct interaction with the 40S ribosomal subunit. In addition, I also showed that ACR sequence originated from HCV IRES can function as an artificial IRES modulated by another cellular protein NF45. These studies shed light on the molecular mechanism of cellular factor on IRES-dependent translation that is still challenging

    ๊ณต๊ฐ„์ •๋ณด๊ธฐ๋ฐ˜ ํ™•์ถฉ์„ ์œ„ํ•œ ์ธ๊ณต์œ„์„ฑ ์˜์ƒ์ž๋ฃŒ ํ™œ์šฉ๋ฐฉ์•ˆ ์—ฐ๊ตฌ(Satelite imagery application for the development of spatial data infrastructure)

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    ๋…ธํŠธ : ์ด ์ฑ…์€ ๊ตญํ† ์—ฐ๊ตฌ์›์˜ ์ž์ฒด ์—ฐ๊ตฌ๋ฌผ๋กœ์„œ ์ •๋ถ€์˜ ์ •์ฑ…์ด๋‚˜ ๊ฒฌํ•ด์™€๋Š” ์ƒ๊ด€์—†์Œ์„ ๋ฐํ˜€๋‘ก๋‹ˆ๋‹ค

    ์ž…์ง€์„ ์ •์„ ์œ„ํ•œ GIS ํ™œ์šฉ๋ฐฉ์•ˆ ์—ฐ๊ตฌ(GIS application for site selection)

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    ๋…ธํŠธ : ์ด ๋ณด๊ณ ์„œ๋Š” ๊ตญ๊ฐ€์ง€๋ฆฌ์ •๋ณด์ฒด๊ณ„ ๊ตฌ์ถ•์‚ฌ์—… ์ง€์›์—ฐ๊ตฌ์˜ ์ผํ™˜์œผ๋กœ ๊ตญํ† ๊ฐœ๋ฐœ์—ฐ๊ตฌ์›์ด ์ˆ˜ํ–‰ํ•œ ์—ฐ๊ตฌ๊ฒฐ๊ณผ๋ฌผ์ž…๋‹ˆ๋‹ค

    Analysis of the impact of monitoring and supervision on organizational performance of public institutions

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    ํ•™์œ„๋…ผ๋ฌธ(์„์‚ฌ) -- ์„œ์šธ๋Œ€ํ•™๊ต๋Œ€ํ•™์› : ํ–‰์ •๋Œ€ํ•™์› ๊ณต๊ธฐ์—…์ •์ฑ…ํ•™๊ณผ, 2022. 8. ๊น€์ค€๊ธฐ.์‚ฌํšŒ๊ฐ€ ๋‹ค๋ณ€ํ™”ํ•จ์— ๋”ฐ๋ผ ๋‚ ๋กœ ์ฆ๊ฐ€ํ•˜๋Š” ๊ณต๊ณต์„œ๋น„์Šค ์ˆ˜์š”์— ๋Œ€์‘ํ•˜๊ธฐ ์œ„ํ•ด ๊ณต๊ณต๊ธฐ๊ด€์˜ ์—ญํ• ์€ ์ง€์†์ ์œผ๋กœ ํ™•๋Œ€๋˜์—ˆ๋‹ค. ๊ณต๊ณต๊ธฐ๊ด€์€ ์—…๋ฌด ์ˆ˜ํ–‰ ๊ณผ์ •์—์„œ ์ฃผ์ธ-๋Œ€๋ฆฌ์ธ ๊ด€๊ณ„์— ๋†“์—ฌ์žˆ๋Š” ๋‹ค์–‘ํ•œ ์ฃผ์ฒด๋“ค์˜ ๊ฐ์‹œโ€ง๊ฐ๋…์„ ๋ฐ›๊ฒŒ ๋œ๋‹ค. ์ด๋ฅผ ํ†ตํ•ด ๊ณต๊ณต๊ธฐ๊ด€์ด ๋ณธ๋ž˜์˜ ๋ชฉํ‘œ๋ฅผ ์ถ”๊ตฌํ•˜๊ณ  ๋„๋•์  ํ•ด์ด๋ฅผ ์ตœ์†Œํ™”ํ•˜๋„๋ก ํ•จ์œผ๋กœ์จ ๊ตญ๋ฏผ๋“ค์ด ๊ธฐ๋Œ€ํ•˜๋Š” ๋ฐฉํ–ฅ์œผ๋กœ ์‚ฌ์—…์„ ์ถ”์ง„ํ•˜๊ณ  ๊ฒฝ์˜ํ•˜๊ฒŒ ํ•˜์—ฌ ์ข…๊ตญ์ ์œผ๋กœ ๊ณต๊ณต๊ธฐ๊ด€์˜ ๊ฒฝ์˜์„ฑ๊ณผ๋ฅผ ํ–ฅ์ƒ์‹œํ‚จ๋‹ค๋Š” ๊ฒƒ์ด ์ฃผ์ธ-๋Œ€๋ฆฌ์ธ ์ด๋ก ์˜ ์„ค๋ช…์ด๋‹ค. ๋ณธ ์—ฐ๊ตฌ๋Š” ๊ณต๊ณต๊ธฐ๊ด€์— ๋Œ€ํ•œ ๊ฐ์‹œโ€ง๊ฐ๋… ํ™œ๋™์ด ๊ฒฝ์˜์„ฑ๊ณผ๋ฅผ ๋†’์ด๋Š” ๋ฐ ๊ธฐ์—ฌํ•  ๊ฒƒ์ด๋ผ๋Š” ์ด๋ก ๊ณผ ์„ ํ–‰์—ฐ๊ตฌ ๊ฒฐ๊ณผ๋ฅผ ์‹ค์ฆ์ ์œผ๋กœ ์ž…์ฆํ•˜๊ณ ์ž ํ•˜์˜€๋‹ค. ๊ณต๊ณต์„ฑ๊ณผ ์ˆ˜์ต์„ฑ์„ ๋™์‹œ์— ์ถ”๊ตฌํ•ด์•ผ ํ•˜๋Š” ๊ณต๊ณต๊ธฐ๊ด€์˜ ๊ฒฝ์˜์„ฑ๊ณผ๋Š” ํšจ๊ณผ์„ฑ, ํšจ์œจ์„ฑ, ์ฑ…์ž„์„ฑ ๋“ฑ ๋‹ค์–‘ํ•œ ์ฐจ์›์—์„œ ๊ฒ€์ฆ๋˜์–ด์•ผ ํ•œ๋‹ค. ๋ณธ ์—ฐ๊ตฌ์—์„œ๋Š” ์ข…ํ•ฉ๊ฒฝ์˜์„ฑ๊ณผ๋กœ์„œ ๊ฒฝ์˜ํ‰๊ฐ€ ๊ฒฐ๊ณผ, ์žฌ๋ฌด์  ์„ฑ๊ณผ, ๊ณ ๊ฐ๋งŒ์กฑ๋„, ์ฒญ๋ ด๋„๋ฅผ ์ข…์†๋ณ€์ˆ˜๋กœ ์„ค์ •ํ•˜์˜€๊ณ , ์ด์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๋…๋ฆฝ๋ณ€์ˆ˜๋กœ ๊ตญ๋ฏผ์„ ๋Œ€ํ‘œํ•˜๋Š” ๊ตญํšŒ์˜ ๊ตญ์ •๊ฐ์‚ฌ, ๊ฐ์‚ฌ์›๊ณผ ์ฃผ๋ฌด๋ถ€์ฒ˜์˜ ๊ฐ์‹œโ€ง๊ฐ๋…, ๊ตญ๋ฏผ์˜ ์ง์ ‘์ ์ธ ๊ฐ์‹œโ€ง๊ฐ๋… ํ™œ๋™์„ ์„ค์ •ํ•˜์—ฌ ๋ถ„์„ํ•˜์˜€๋‹ค. ๋ถ„์„ ๊ฒฐ๊ณผ ๊ตญ์ •๊ฐ์‚ฌ๋Š” ๊ณต๊ณต๊ธฐ๊ด€ ๊ฒฝ์˜ํ‰๊ฐ€์™€ ์žฌ๋ฌด์  ์„ฑ๊ณผ์— ๊ธ์ •์  ์˜ํ–ฅ์„ ๋ฏธ์ณค์œผ๋ฉฐ ์‹œ์ •์š”๊ตฌ์‚ฌํ•ญ์„ ๋‚ด์šฉ์— ๋”ฐ๋ผ ๋ถ„๋ฅ˜ํ•ด๋ณผ ๋•Œ ๊ณต๊ณต๊ธฐ๊ด€ ์‚ฌ์—…์— ๊ด€ํ•œ ์ง€์ ์ด ๊ฒฝ์˜ํ‰๊ฐ€ ๊ฒฐ๊ณผ์— ๊ธฐ์—ฌํ•˜๋Š” ๊ฒƒ์œผ๋กœ ํ™•์ธ๋˜์—ˆ๋‹ค. ์ •๋ถ€๋ถ€์ฒ˜์˜ ๊ฐ์‹œโ€ง๊ฐ๋… ์ค‘์—์„œ๋Š” ์ฃผ๋ฌด๋ถ€์ฒ˜์˜ ์ง€์ ์ด ๊ฒฝ์˜ํ‰๊ฐ€ ๊ฒฐ๊ณผ์— ๊ธ์ •์  ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ๋‹ค. ๋งˆ์ง€๋ง‰์œผ๋กœ ๊ตญ๋ฏผ์ด ์ง์ ‘ ๊ณต๊ณต๊ธฐ๊ด€ ๊ฒฝ์˜ํ™œ๋™์„ ๊ฐ์‹œํ•˜๋Š” ํ™œ๋™ ์ค‘ ์ •๋ณด๊ณต๊ฐœ์ฒญ๊ตฌ๊ฐ€ ๊ณ ๊ฐ๋งŒ์กฑ๋„๋ฅผ ๋†’์ด๋Š” ๋ฐ ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๊ฒƒ์œผ๋กœ ๋ถ„์„๋˜์—ˆ๋‹ค. ๊ฒฐ๋ก ์ ์œผ๋กœ ๋ณธ ์—ฐ๊ตฌ์—์„œ ๋‹ค์–‘ํ•œ ๊ฐ์‹œโ€ง๊ฐ๋… ํ™œ๋™์ด ๊ณต๊ณต๊ธฐ๊ด€์˜ ๊ฒฝ์˜์„ฑ๊ณผ์— ๋ฏธ์น˜๋Š” ์˜ํ–ฅ์— ๋Œ€ํ•œ ๊ฐ€์„ค๋“ค์ด ๋ชจ๋‘ ์ฑ„ํƒ๋˜์ง€๋Š” ๋ชปํ•˜์˜€์ง€๋งŒ, ๊ฐ์‹œโ€ง๊ฐ๋… ํ™œ๋™๋ณ„๋กœ ํŠน์ • ๊ฒฝ์˜์„ฑ๊ณผ์— ์œ ์˜ํ•œ ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๊ฒƒ์„ ํ™•์ธํ•  ์ˆ˜ ์žˆ์–ด ์ผ๋ถ€ ๊ฐ€์„ค๋“ค์„ ์ฑ„ํƒํ•  ์ˆ˜ ์žˆ์—ˆ๋‹ค. ๋ณธ ์—ฐ๊ตฌ๋Š” ๊ณต๊ณต๊ธฐ๊ด€์˜ ๊ฒฝ์˜์„ฑ๊ณผ๋ฅผ ๊ฐ๊ด€์ ์œผ๋กœ ์ธก์ •ํ•˜๊ณ  ๊ทธ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๊ฐ์‹œโ€ง๊ฐ๋… ์š”์ธ๋“ค์„ ์‹ค์ฆ์ ์œผ๋กœ ๋ถ„์„ํ•œ ๋ฐ ์˜์˜๊ฐ€ ์žˆ๋‹ค. ํŠนํžˆ ๊ตญ์ •๊ฐ์‚ฌ์™€ ์ฃผ๋ฌด๋ถ€์ฒ˜ ๊ฐ์‚ฌ๋Š” ๊ณต๊ณต๊ธฐ๊ด€ ๊ฒฝ์˜์„ ํ†ต์ œํ•˜๊ณ  ์ž์œจ์„ฑ์„ ํ•ด์น˜๋Š” ๊ฒƒ์œผ๋กœ ์ธ์‹๋˜๊ธฐ ์‰ฌ์šฐ๋‚˜ ๊ฒฝ์˜ํ‰๊ฐ€์— ๋„์›€์ด ๋˜๋Š” ๊ฒƒ์œผ๋กœ ๋ถ„์„๋˜์–ด ์ง€์ ์‚ฌํ•ญ์„ ๊ฒฝ์˜ ๊ฐœ์„ ์— ํ™œ์šฉํ•  ํ•„์š”๊ฐ€ ์žˆ์Œ์„ ์‹œ์‚ฌํ•œ๋‹ค. ๋‹ค๋งŒ ๊ฒฝ์˜์„ฑ๊ณผ ์ค‘ ์ฒญ๋ ด๋„์˜ ๊ฒฝ์šฐ ๊ฐ€์„ค๊ณผ ๋ฐ˜๋Œ€๋กœ ๊ฐ์‹œโ€ง๊ฐ๋… ํ™œ๋™์ด ๋ถ€์ •์  ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚˜ ์ถ”๊ฐ€์ ์ธ ๋ณ€์ˆ˜์˜ ๋ฐœ๊ตด ๋“ฑ์ด ์—ฐ๊ตฌ์˜ ๊ณผ์ œ๋กœ ๋‚จ์•˜๋‹ค.As society diversifies, the role of public institutions has been continuously expanded to respond to the ever-increasing demand for public services. Public institutions are subject to the supervision of various entities in the principal-agent relationship in the course of their missions. Principal-agent theory explains that through this supervision public institutions pursue their original goals and minimize moral hazard, thereby promoting and managing the business in the direction expected by the people, ultimately improving the organizational performance of public institutions. This study is intended to empirically prove the theory and previous research results that monitoring and supervising public institutions would contribute to improve business performance. The organizational performance of public institutions that must pursue both publicness and profitability must be verified in various dimensions such as effectiveness, efficiency and responsibility. In this study, government management evaluation, financial performance, customer satisfaction and integrity of public institutions are set as dependent variables while audits of the National Assembly, monitoring and supervision of the Board of Audit and Inspection, audit and inspection of the government ministries, direct monitoring and supervision activities of the people are set as independent variables. As a result, it was confirmed that the National Assembly audit and inspection had a positive effect on the organizational performance and financial performance of public institutions. Regarding the audit and inspection of government ministries, opinions of the department in charge had a positive effect on the results of the government management evaluation. Lastly, information disclosure request in monitoring and supervision activities of the people has an effect on increasing customer satisfaction. In conclusion, although we cannot adopt all of the hypotheses on the effects of various monitoring/supervision activities on the organizational performance of public institutions this study, we can confirm that each monitoring/supervision activity has a significant effect on specific performance. This study is meaningful in that it objectively measures the organizational performance of public institutions and empirically analyzes the monitoring and supervision factors that affect them. While audits of National Assembly and audits and inspections of government ministries are easily perceived as controlling the management of public institutions and impairing the autonomy of public institutions, this study shows that it is helpful in government management evaluation, suggesting that requests for correction need to be utilized for the management improvement of public institutions. On the other hand, as monitoring and supervising public institutions have a negative effect on the integrity of public institutions, so the excavation of additional variables remained a task for the study.์ œ 1 ์žฅ ์„œ๋ก  1 ์ œ 1 ์ ˆ ์—ฐ๊ตฌ์˜ ๋ชฉ์ ๊ณผ ํ•„์š”์„ฑ 1 ์ œ 2 ์ ˆ ์—ฐ๊ตฌ์˜ ๋Œ€์ƒ๊ณผ ๋ฐฉ๋ฒ• 3 ์ œ 2 ์žฅ ์ด๋ก ์  ๋…ผ์˜์™€ ์„ ํ–‰์—ฐ๊ตฌ ๊ฒ€ํ†  6 ์ œ 1 ์ ˆ ์ด๋ก ์  ๋…ผ์˜ 6 1. ๋Œ€๋ฆฌ์ธ ์ด๋ก  6 2. ํ†ต์ œ๋กœ์„œ์˜ ๊ฐ์‹œ๊ฐ๋…์— ๊ด€ํ•œ ์ด๋ก  8 3. ๊ณต๊ณต๊ธฐ๊ด€์— ๋Œ€ํ•œ ๊ฐ์‹œ๊ฐ๋… ์ œ๋„ ํ˜„ํ™ฉ 9 4. ์กฐ์ง์„ฑ๊ณผ์— ๊ด€ํ•œ ์ด๋ก  15 ์ œ 2 ์ ˆ ์„ ํ–‰์—ฐ๊ตฌ ๊ฒ€ํ†  17 1. ํ†ต์ œ์˜ ์„ฑ๊ณผ ์˜ํ–ฅ์— ๊ด€ํ•œ ์—ฐ๊ตฌ 17 2. ์ฃผ์ฒด๋ณ„ ํ†ต์ œ์˜ ์˜์˜์— ๊ด€ํ•œ ์—ฐ๊ตฌ 21 ์ œ 3 ์žฅ ์—ฐ๊ตฌ ์„ค๊ณ„ 25 ์ œ 1 ์ ˆ ์—ฐ๊ตฌ์˜ ๋ถ„์„ํ‹€ 25 ์ œ 2 ์ ˆ ๋ณ€์ˆ˜์˜ ์„ค์ • 28 1. ์ข…์†๋ณ€์ˆ˜์˜ ์„ค์ • ๋ฐ ์ธก์ • 28 2. ๋…๋ฆฝ๋ณ€์ˆ˜์˜ ์„ค์ • ๋ฐ ์ธก์ • 29 3. ํ†ต์ œ๋ณ€์ˆ˜์˜ ์„ค์ • ๋ฐ ์ธก์ • 30 ์ œ 3 ์ ˆ ์—ฐ๊ตฌ๊ฐ€์„ค๊ณผ ๋ถ„์„๋ชจํ˜• 32 1. ์—ฐ๊ตฌ๊ฐ€์„ค ์„ค์ • 32 2. ๋ถ„์„๋ชจํ˜• 35 ์ œ 4 ์žฅ ์‹ค์ฆ๋ถ„์„ ๊ฒฐ๊ณผ 36 ์ œ 1 ์ ˆ ๊ธฐ์ดˆํ†ต๊ณ„๋ถ„์„ 36 1. ๋…๋ฆฝ๋ณ€์ˆ˜ ๋ถ„์„ 36 2. ์ข…์†๋ณ€์ˆ˜ ๋ถ„์„ 37 3. ํ†ต์ œ๋ณ€์ˆ˜ ๋ถ„์„ 39 4. ์ƒ๊ด€๊ด€๊ณ„ ๋ถ„์„ 40 5. ๋‹ค์ค‘๊ณต์„ ์„ฑ ๊ฒ€์ฆ 40 ์ œ 2 ์ ˆ ๋‹ค์ค‘ํšŒ๊ท€ ๋ถ„์„ 43 1. ์ข…ํ•ฉ๊ฒฝ์˜์„ฑ๊ณผ์— ๋Œ€ํ•œ ๋ถ„์„ ๊ฒฐ๊ณผ 43 2. ์žฌ๋ฌด์  ์„ฑ๊ณผ์— ๋Œ€ํ•œ ๋ถ„์„ ๊ฒฐ๊ณผ 52 3. ๊ณ ๊ฐ๋งŒ์กฑ๋„์— ๋Œ€ํ•œ ๋ถ„์„ ๊ฒฐ๊ณผ 57 4. ์ฒญ๋ ด๋„์— ๋Œ€ํ•œ ๋ถ„์„ ๊ฒฐ๊ณผ 61 5. ๊ฐ์‹œ๊ฐ๋… ํ™œ๋™์˜ ๊ฒฝ์˜์„ฑ๊ณผ์— ๋Œ€ํ•œ ๋‹ค์ค‘ํšŒ๊ท€ ๋ถ„์„ ๊ฒฐ๊ณผ์ข…ํ•ฉ 65 ์ œ 5 ์žฅ ๊ฒฐ๋ก  71 ์ œ 1 ์ ˆ ์—ฐ๊ตฌ๊ฒฐ๊ณผ์˜ ์š”์•ฝ 71 ์ œ 2 ์ ˆ ์—ฐ๊ตฌ์˜ ์‹œ์‚ฌ์  75 ์ œ 3 ์ ˆ ์—ฐ๊ตฌ์˜ ํ•œ๊ณ„ 78 ์ฐธ๊ณ ๋ฌธํ—Œ 81 Abstract 85์„

    A Study on the Plurality of Movement

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