114 research outputs found
An Empirical Study of Open Source Business Model Innovation based on Red Hat’s Case
MasterThe software area has moved at a quick pace to be one of the largest industries in the world. Open source opened new business way in software area. Open source was relatively big innovation. Many vendors adapt to open source business model for their benefit. Linux is a representative of the open source software. Red Hat has become associated to a large extent with Linux successfully. In this study, we attempt to understand the successful factors of Red Hat. Although Red Hat’s business is based on the open source, they make a benefit from the enterprises. The Red Hat business model was examined by interviews based on 10 Linux professionals. We have highlighted how many aspects of open source business model. This paper has reviewed the case of open source business model innovation of the growing open source in the software market. Author classified 5 innovative characteristics of the Red Hat business model based on the result of the interviews and references. Therefore, these characteristics can lead to robust revenue streams in future open source business model
Mesozooplankton Distribution in the Southern Yellow Sea in Autumn
We investigated the mesozooplankton community structure during autumn in the southern Yellow Sea. Mesozooplankton density generally ranged from 352 to 2,954 ind. m-3 and varied according to different sampling stations. The copepod Paracalanus parvus s.l. and its copepodites dominated in the communities, corresponding to 57.3% in density of the total. Surface and water-column averaged salinity were positively correlated with density of total mesozooplankton, copepods and a few dominant species, and the tunicate Thalia rhomboides was negatively related to chlorophyll-a concentration. The mesozooplankton community of the study area was divided into three groups according to the cluster analysis using species composition and density: one in the northern coastal region, another in the northern offshore region, and the other in the south. The most significant indicator species for each of the groups were Labidocera euchaeta in the northern coastal region, T. rhomboides in the northern offshore region, and Themisto sp. juveniles in the south. This study provides recent data on the characteristics of the mesozooplankton community in the southern Yellow Sea, which may be valuable for gaining a better understanding of changes in the pelagic ecosystem of the Yellow Sea.11Nscopuskc
Feeding impact of the planktonic copepod Calanus sinicus on phytoplankton in the northern East China Sea in late spring
The distribution and feeding of Calanus sinicus were studied in June 2015 on the 12 sampling stations spread from the southern coast of Korea to the northern East China Sea, to better understand an ecological role of C. sinicus in the research area. Ingestion rate, daily ration as percentage body weight and feeding impact of copepodite stage CIV to adults were estimated using the gut pigment method. Density of overall C. sinicus was varied from 2 to 1,387 inds. m-3 by stations. CV copepodite was the most abundant with the density of 273.7 inds. m-3 and CIV was next, followed by adult female and male. The gut pigment content of the copepodites of C. sinicus ranged from 3.2 to 5.5 ng chl. ind-1 with the highest value in the adult female. Although the gut pigment content and ingestion rate of adult female were higher than other developmental stages, the highest value of daily ration as percentage body weight was found at CIV copepodite. These results confirm that the feeding of copepodites of C. sinicus is more active than that of adults. Mean feeding impact of the copepodites of C. sinicus on phytoplankton biomass, in terms of chlorophyll a concentration, ranged from 0.1 to 2.6% with the highest value in the copepodite CV. No significant correlations was found between density, ingestion rate and feeding impact of C. sinicus and the environmental factors such as temperature, salinity or chlorophyll a concentrations.rch area. Ingestion rate, daily ration as percentage body weight and feeding impact of copepodite stage CIV to adults were estimated using the gut pigment method. Density of overall C. sinicus was varied from 2 to 1,387 inds. m-3 by stations. CV copepodite was the most abundant with the density of 273.7 inds. m-3 and CIV was next, followed by adult female and male. The gut pigment content of the copepodites of C. sinicus ranged from 3.2 to 5.5 ng chl. ind-1 with the highest value in the adult female. Although the gut pigment content and ingestion rate of adult female were higher than other developmental stages, the highest value of daily ration as percentage body weight was found at CIV copepodite. These results confirm that the feeding of copepodites of C. sinicus is more active than that of adults. Mean feeding impact of the copepodites of C. sinicus on phytoplankton biomass, in terms of chlorophyll a concentration, ranged from 0.1 to 2.6% with the highest value in the copepodite CV. No significant correlations was found between density, ingestion rate and feeding impact of C. sinicus and the environmental factors such as temperature, salinity or chlorophyll a concentrations.1
Secondary production of Acartia steueri and A. omorii (Copepoda: Calanoida) in a small bay, southeastern coast of Korea: The growth rate approach
Secondary production of marine calanoid copepod Acartia steueri and A. omorii were measured from 2 October 1991 to 8 October 1992 at a station in a small bay on the southeastern coast of Korea, using the traditional growth rate method. Phytoplankton standing stock ranged from 1.0 to 9.3 mg chl.a m-3. The two Acartia species were present throughout the year, while seasonal variation was found for their abundance. Biomass of A. steueri was averaged at 0.68 mgC m-3 with peaks in November, February, May, and July-early August, and relatively low biomass in September-January. For A. omorii, the biomass was averaged at 0.44 mgC m-3, with peaks in February and July, and relatively low biomass in late summer and fall. Annual production of A. steueri was 25.1 mgC m-3 yr-1 (or 166 mgC m-2 yr-1), showing peaks in November, May, and July-August with a small peak in February, and low production in December-April and September-October. For A. omorii, annual production was 33.5 mgC m-3 yr-1 (or 221 mgC m-2 yr-1), with peaks in February and July. There was no significant relationship of the daily production rate of A. steueri to water temperature or chlorophyll a concentration. However, the daily production rate of A. omorii was significantly correlated with chlorophyll a concentration, indicating that phytoplankton was the major influencing factor for seasonal variation of production of A.omorii in the bPhytoplankton standing stock ranged from 1.0 to 9.3 mg chl.a m-3. The two Acartia species were present throughout the year, while seasonal variation was found for their abundance. Biomass of A. steueri was averaged at 0.68 mgC m-3 with peaks in November, February, May, and July-early August, and relatively low biomass in September-January. For A. omorii, the biomass was averaged at 0.44 mgC m-3, with peaks in February and July, and relatively low biomass in late summer and fall. Annual production of A. steueri was 25.1 mgC m-3 yr-1 (or 166 mgC m-2 yr-1), showing peaks in November1
Secondary production of Acartia steueri and A. omorii (Copepoda: Calanoida) in a small bay, southeastern coast of Korea: The growth rate approach
Secondary production of marine calanoid copepod Acartia steueri and A. omorii were measured from 2 October 1991 to 8 October 1992 at a station in a small bay on the southeastern coast of Korea, using the traditional growth rate method. Phytoplankton standing stock ranged from 1.0 to 9.3 mg chl.a m-3. The two Acartia species were present throughout the year, while seasonal variation was found for their abundance. Biomass of A. steueri was averaged at 0.68 mgC m-3 with peaks in November, February, May, and July-early August, and relatively low biomass in September-January. For A. omorii, the biomass was averaged at 0.44 mgC m-3, with peaks in February and July, and relatively low biomass in late summer and fall. Annual production of A. steueri was 25.1 mgC m-3 yr-1 (or 166 mgC m-2 yr-1), showing peaks in November, May, and July-August with a small peak in February, and low production in December-April and September-October. For A. omorii, annual production was 33.5 mgC m-3 yr-1 (or 221 mgC m-2 yr-1), with peaks in February and July. There was no significant relationship of the daily production rate of A. steueri to water temperature or chlorophyll a concentration. However, the daily production rate of A. omorii was significantly correlated with chlorophyll a concentration, indicating that phytoplankton was the major influencing factor for seasonal variation of production of A.omorii in the bPhytoplankton standing stock ranged from 1.0 to 9.3 mg chl.a m-3. The two Acartia species were present throughout the year, while seasonal variation was found for their abundance. Biomass of A. steueri was averaged at 0.68 mgC m-3 with peaks in November, February, May, and July-early August, and relatively low biomass in September-January. For A. omorii, the biomass was averaged at 0.44 mgC m-3, with peaks in February and July, and relatively low biomass in late summer and fall. Annual production of A. steueri was 25.1 mgC m-3 yr-1 (or 166 mgC m-2 yr-1), showing peaks in November1
Reichenbachs constructive axiomatization : Its significance and limitation
학위논문 (석사)-- 서울대학교 대학원 : 협동과정 과학사및과학철학전공, 2011.2. 조인래.Maste
3D model of copepod Corycaeus speciosus
본 디자인은 눈에 잘 보이지 않고 현미경을 통하여 잘 관찰할 수 있는 해양생물(요각류)을 3D 모델링하
여 3D 프린터를 이용해 모형으로 만들어, 일반적인 전시 및 체험학습으로 쉽게 접근하지 못했던 작은 생물
을 모형으로 직접 만져보고 눈으로 확인하여 생물에 대한 학습효과를 높일 수 있도록 하였음
Effects of octreotide in small bowel obstruction of rats.
의과학사업단/석사[한글]
장폐쇄는 외과 영역에서 흔하게 접할 수 있는 질환으로 장관내 감압을 위해서 1930년대 개발된 비위관 삽입이 현재까지 가장 많이 사용되는 치료 술기이다. 소화기계 분비 억제 약물인 octreotide는 장관내 수분, 전해질 흡수를 촉진시켜 장폐쇄 환자의 증상을 감소시
키며 특히 말기 암환자들의 장폐쇄에 비위관을 대신할 수 있다는 연구들이 보고되고 있다. 이에 연구자들은 소장폐쇄 백서 모델에게 octreotide를 투여하여 치료 시간에 따른 장관내액과 전해질, 그리고 점막 조직의 변화를 알아보고자 하였다.
40마리의 체중 200∼500g의 수컷 Sprague-Dawley(SD)계 흰쥐를 개복하여 말단 회장을 실로 묶되 20마리는 완전 폐쇄, 20마리는 부분 폐쇄를 하였다. 대조군은 수술 후 1ml/kg의 생리식염수와 12시간마다 50ml/kg/day의 수액을 주입하였고 실험군은 수액과 함께 100 μg/kg의 octreotide를 투여하였다. 이들을 두 군으로 나누어 수술 후 24시간 및 48시간이 지난 후 각각 다시 개복하여 소장내액과 회장 조직을 채취한 후 희생시켰다. 소장내액의 총량, 원심분리후 양, Na^+, K^+, Cl^-, tCO₂를 조사하였고 회장 조직은 조직 병리 슬라이드를 제작해 점막 손상 점수를 조사하였다.
완전 폐쇄군의 경우, 실험군에서는 24시간 군과 48시간 군에서 모두 대조군에 비해 장관내액이 감소하였으나 통계학적 의미는 없었고, 전해질은 48시간군에서 tCO₂가 의미있게 증가하였으며 소장 점막손상이 대조군에 비해 의미있게 적었다.
부분 폐쇄군의 경우는 실험군이 대조군보다 장관내액이 증가한 것으로 나타났으나 통계학적 차이는 없었고, 오히려 24시간군에서 대조군에 비해 Cl-가 높게 측정되었다.
소장 완전 폐쇄 모델에서 octreotide는 48시간 투여시 점막 보호 효과가 있었으며 완전 폐쇄, 부분 폐쇄 모델 모두에서 소장내액량과 전해질은 차이를 보이지 않았다. 따라서 octreotide를 장폐쇄 환자에게 사용하기 위해서는 좀더 많은 동물 실험과 임상 연구가 필요
할 것으로 생각된다.
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핵심되는 말 : Octreotide, 장폐쇄
[영문]
Intestinal obstruction is a common disorder in surgical practice. The major morbidity of intestinal obstruction relates to intestinal distention and ischemia.
Gastrointestinal decompression by nasogastric or intestinal tubes developed in 1930s has been an only medical treatment modality.
Octreotide, the long acting somatostatin analogue, has recently been made available for clinical use. This synthetic peptide possesses a broad spectrum of physiologic action including the inhibition of gastrointestinal secretion. We hypothesized that octreotide, a potent inhibitor of intestinal secretion, can
improve the intestinal absorption and secretion processes in intestinal obstruction.
Forty Sprague-Dawley rats were randomly assigned to four groups; Group Ⅰ: complete obstruction for 24 hours(24CO), Group Ⅱ: complete obstruction for 48 hours(48CO), Group Ⅲ: partial obstruction for 24 hours(24PO), Group Ⅳ : partial obstruction for 48 hours(48PO). The rats were anesthetized with intraperitoneal injection of thiopental and were subjected to complete or partial ileal obstruction. Each group consisted of five control and five treated rats. The treated rats received octreotide (100㎍/㎏) while the controls received the same
quantity of saline every 12 hours for 24 or 48 hours. After 24 or 48 hours, the volume of small bowel contents were measured. The volume and the concentration of Na^+, K^+, Cl^-, tCO₂ after centrifugation were also analyzed. Ileal segments proximal to obstruction were harvested, fixed, stained and the pathological changes were evaluated with mucosal damage scores.
There was no difference in the volume and electrolyte composition of intestinal fluid among 4 groups. In 48CO group, octreotide-treated rats showed statistically lower mucosal damage scores than control rats (p<0.05).
In conclusion, octreotide exerted mucosal protecting effect in complete intestinal obstruction rat model.ope
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