4 research outputs found

    上皮性卵巢癌中Gal-3和Bcl-2的表达及临床意义

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    【目的】检测半乳糖凝集素-3(Gal-3)、B淋巴细胞瘤/白血病蛋白-2(Bcl-2)在上皮性卵巢癌组织中的表达,探 究二者与相关临床病理特征及预后关系,检验它们作为预测预后标记物的可能性。【方法】采用免疫组织化学方法,检测 98例上皮性卵巢癌组织、10例正常卵巢组织中Gal-3和Bcl-2的表达,分析二者与临床病理特征、预后的关系。【结果】98例 上皮性卵巢癌中,Gal-3、Bcl-2均为胞浆表达,Gal-3阳性率为76.5%(75/98),Bcl-2阳性率为51.0%(50/98),正常卵巢上皮不 表达Gal-3、Bcl-2蛋白。Gal-3与Bcl-2相关性无统计学意义。Gal-3表达与病理类型、铂敏感性相关(P = 0.043,P = 0.038), Bcl-2表达与FIGO分期相关(P = 0.029)。Cox单因素分析显示上皮性卵巢癌Gal-3表达(P = 0.008)、Bcl-2表达(P = 0.021)、 分期(P < 0.001)、铂敏感性(P < 0.001)是影响术后生存的因素,而Cox多因素分析中则只有Gal-3表达(P = 0.014)、铂敏感 性(P = 0.021)、分期(P < 0.001)才是独立预后因素。【结论】Gal-3、Bcl-2可能参与上皮性卵巢癌的发生发展。Gal-3表达与 病理类型、铂敏感性、预后相关,可能成为上皮性卵巢癌预后的独立判定因子

    Measurement of integrated luminosity of data collected at 3.773 GeV by BESIII from 2021 to 2024*

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    Amplitude analysis of the decays D0π+ππ+πD^0\rightarrow\pi^+\pi^-\pi^+\pi^- and D0π+ππ0π0D^0\rightarrow\pi^+\pi^-\pi^0\pi0

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    Determination of the number of ψ(3686) events taken at BESIII

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    The number of ψ(3686) events collected by the BESIII detector during the 2021 run period is determined to be (2259.3±11.1)×106 by counting inclusive ψ(3686) hadronic events. The uncertainty is systematic and the statistical uncertainty is negligible. Meanwhile, the numbers of ψ(3686) events collected during the 2009 and 2012 run periods are updated to be (107.7±0.6)×106 and (345.4±2.6)×106, respectively. Both numbers are consistent with the previous measurements within one standard deviation. The total number of ψ(3686) events in the three data samples is (2712.4±14.3)×10^
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