31 research outputs found
Detection on Proper Wearing of Seat Belt Based on Infrared Mark Vision
针对安全带佩戴规范性仍未引起充分重视的现实问题,借助具有红外敏感表面涂层标记的三点式安全带,基于标记视觉和图像处理技术提出一种安全带佩戴规范性的; 集成检测方法:利用增强现实技术快速识别定位安全带标记,在此基础上分别设计数量阈值算法、模糊聚类阈值算法、曲线拟合松弛度算法和肩部外轮廓交点定位算; 法,用以进行安全带是否佩戴和佩戴形式、松紧程度、高低位置是否规范等4种判断,从而实现安全带是否规范佩戴的检测目标。实验结果表明,在各种成像条件和; 图像背景干扰下,对应上述4种判断的识别准确率分别为95.4%, 93.1%,; 79.5%和85.3%,而安全带佩戴规范性的综合识别准确率达89.5%,验证了所提出算法的准确性、有效性和适应能力。In view of the problem that whether seat belt is properly used or not; haven't yet attracted sufficient attention,an integrated detection; method of the proper use of seat belt is proposed by means of the; three-point safety belt with infrared-ray-sensitive coat marks and based; on mark vision and image processing technologies: Augmented reality; technology is used to rapidly identify and locate the marks on seat; belt,based on which the algorithms of number threshold,fuzzy clustering; threshold,curve fitting relaxation and shoulder profile intersection; locating are developed respectively to conduct four judgments of weather; seat belt is used or not,the wearing forms of seat belt, belt tightness; and belt height,and hence achieve the detection goal of the proper use; of seat belt. Experiment results show that under various image forming; conditions and image background interferences,the identification; accuracies of the algorithms used corresponding to above mentioned four; judgments are 95.4%,93.1%,79.5% and 85.3% respectively with an overall; identification accuracy of 89.5%,verifying the correctness,effectiveness; and adaptability of the algorithms proposed.国家自然科学基金; 福建省自然科学基
Synthesis of magnetic, fluorescent and mesoporous core-shell-structured nanoparticles for imaging, targeting and photodynamic therapy
通讯作者地址: Chen, XL (通讯作者),Xiamen Univ, Coll Chem & Chem Engn, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R ChinaA synthetic method to prepare novel multifunctional core-shell-structured mesoporous silica nanoparticles for simultaneous magnetic resonance (MR) and fluorescence imaging, cell targeting and photosensitization treatment has been developed. Superparamagnetic magnetite nanoparticles and fluorescent dyes are co-encapsulated inside nonporous silica nanoparticles as the core to provide dual-imaging capabilities (MR and optical). The photosensitizer molecules, tetra-substituted carboxyl aluminum phthalocyanine (AlC(4)Pc), are covalently linked to the mesoporous silica shell and exhibit excellent photo-oxidation efficiency. The surface modification of the core-shell silica nanoparticles with folic acid enhances the delivery of photosensitizers to the targeting cancer cells that overexpress the folate receptor, and thereby decreases their toxicity to the surrounding normal tissues. These unique advantages make the prepared multifunctional core-shell silica nanoparticles promising for cancer diagnosis and therapy.NSFC21021061,20925103,20871100,Fok Ying Tung Education Foundation 121011
NSF of Fujian Province 2009J06005
Fundamental Research Funds for the Central Universities 2010121015
Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministr
Electric-field-induced selective catalysis of single-molecule reaction
随着单分子电学检测技术的迅速发展,分子电子学的研究不再局限于分子电子学器件的构筑及其电学性质的测量,而且扩展到单分子尺度化学反应过程的探索。然而目前相关的研究仍然局限于理论计算方面,在单分子尺度上实时监测和调控化学反应的活性和选择性是化学领域的长期目标和挑战。针对这一挑战,洪文晶教授课题组与程俊教授课题组合作,自主研发了精密科学仪器,将单个有机分子定向连接在两个末端尺寸为原子级的电极之间,解决了化学反应中分子取向控制的问题.理论计算结果证实了定向电场可以有效地稳定化学反应的过渡态,从而降低反应能垒。该研究工作在化学化工学院洪文晶教授、程俊教授、能源材料化学协同创新中心(iChEM)刘俊扬副研究员的共同指导下完成,由硕士研究生黄晓艳、iChEM博士研究生唐淳、博士研究生李洁琼以及兰州大学的陈力川博士作为共同第一作者,化学化工学院师佳副教授、陈招斌高级工程师、夏海平教授和田中群教授,萨本栋微纳研究院杨扬副教授、环境与生态学院白敏冬教授以及兰州大学张浩力教授参与了研究工作的讨论并给予指导,博士后乐家波、博士研究生郑珏婷、张佩(已毕业)、李瑞豪、李晓慧也参与了研究工作。Oriented external electric fields (OEEFs) offer a unique chance to tune catalytic selectivity by orienting the alignment of the electric field along the axis of the activated bond for a specific chemical reaction; however, they remain a key experimental challenge. Here, we experimentally and theoretically investigated the OEEF-induced selective catalysis in a two-step cascade reaction of the Diels-Alder addition followed by an aromatization process. Characterized by the mechanically controllable break junction (MCBJ) technique in the nanogap and confirmed by nuclear magnetic resonance (NMR) in bottles, OEEFs are found to selectively catalyze the aromatization reaction by one order of magnitude owing to the alignment of the electric field on the reaction axis. Meanwhile, the Diels-Alder reaction remained unchanged since its reaction axis is orthogonal to the electric fields. This orientation-selective catalytic effect of OEEFs reveals that chemical reactions can be selectively manipulated through the elegant alignment between the electric fields and the reaction axis.This work was supported by the National Key R&D Program of China (2017YFA0204902), the National Natural Science Foundation of China (21722305, 21703188, 21673195, 21621091, 51733004, 51525303, and 91745103), the China Postdoctoral Science Foundation (2017M622060), and the Young Thousand Talents Project of China.
该工作得到国家自然科学基金委(21722305、21703188、21673195、51733004、51525303、91745103),国家重点研发计划课题(2017YFA0204902),中国博士后面上基金(2017M622060)的资助,以及固体表面物理化学国家重点实验室、醇醚酯化工清洁生产国家工程实验室、能源材料化学协同创新中心的支持
一种用于1,5-戊二酸二甲酯加氢制取1,5-戊二醇的催化剂及方法
本发明涉及一种1,5-戊二酸二甲酯加氢制取1,5-戊二醇的催化剂及其制备方法,催化剂是由活性组分氧化铜,助剂氧化锌、氧化铝三组分组成,在催化剂总重量中氧化铜占40%~60%,氧化锌占20%~50%,氧化铝占10%~20%;其制备方法是将铜、锌和铝的可溶性盐类按其重量比混合用水溶解,在加热搅拌下,用碱溶液中和到pH=7,对其沉淀物进行过滤、洗涤、干燥、焙烧、成型,使用本发明的催化剂进行1,5-戊二酸二甲酯加氢生成1,5-戊二醇,可以实现较低的反应压力,为3~5Mpa,从而能较大地降低生产装置的一次性投资和生产成本,并减小操作的难度。带填
两种绿藻辅助饲喂对克氏原螯虾生理活性的影响
以克氏原螯虾为研究对象,测定了在正常投喂人工颗粒饲料的基础上辅助添加小球藻、刚毛藻饲喂克氏原螯虾的生理活性。结果表明:试验期间添加小球藻(1.0×10^6—1.0×10^7 cells·L^-1)、刚毛藻(0.06—0.08 g·L^-1)对克氏原螯虾的生长与存活率均无显著影响(P>0.05),但肌肉超氧化物歧化酶(SOD)和肝胰脏酸性磷酸酶(ACP)的活性显著降低(P<0.05);机体的血细胞密度显著增加(P<0.05),外骨骼和肌肉中虾青素的含量极显著增加(P<0.01);单独添加刚毛藻肌肉虾青素含量也显著提高(P<0.05),血清、肝胰脏和肌肉碱性磷酸酶(AKP)的活性极显著提高(P<0.01),肝胰脏酸性磷酸酶的活性极显著降低(P<0.01)。摄食小球藻和刚毛藻对于克氏原螯虾的抗逆活性和免疫能力具有促进作用,养殖水体中适度添加小球藻和刚毛藻有助于克氏原螯虾的健康与活力
The Ecotoxicity Effects of Cadmium on Microorganism in Udic-Ferrosols and Aquic-Cambosols
以土壤微生物生物量碳(Cmic)、土壤酶活性及微生物多样性为微生物学指标,以0.01mol·L-1CaCl2作为Cd有效态提取剂,以江西红壤和天津潮土为供试土壤,在室内25℃连续培养28d的条件下探讨了外源Cd对土壤微生物的生态毒理效应。结果表明:1)不同培养时间潮土CaCl2提取态Cd含量均显著低于红壤,潮土微生物受到Cd的抑制作用也明显小于红壤。2)各微生物指标的敏感性不同,并受土壤类型和培养时间的影响,其中,脱氢酶的敏感性强于脲酶,微生物功能多样性指标中BiologEco板上每孔的平均吸光值(AWCD)的敏感性强于Shannon指数;Cmic、脲酶、脱氢酶、AWCD和Shannon指数均..
异氟醚通过醛糖还原酶改善线粒体功能保护脑缺血/再灌注损伤
目的探讨异氟醚(ISO)对脑缺血/再灌注(IR)小鼠线粒体功能的影响及其可能机制。方法醛糖还原酶(AR)基因敲除的小鼠(AR-/-)及对照野生型小鼠(Wild-type,WT)随机分为WT-S组、WT-IR组、WT-IR+ISO组、AR-/-+S组、AR-/-+IR组、AR-/-+IR+ISO组,每组6只。通过线栓法建立小鼠大脑中动脉栓塞模型(缺血1 h,再灌注23 h),Zea-Longa 法评估小鼠神经功能评分,2,3,5-氯化三苯基四氮唑 (TTC)染色评估脑梗塞体积,Western blot检测脑组织AR蛋白表达,免疫荧光定位检测缺血半暗带AR蛋白表达水平,TUNEL法评估缺血半暗带细胞凋亡情况,流式细胞分析线粒体通透性转换孔(MPTP)的开放程度。结果脑缺血/再灌注损伤引起小鼠神经功能缺损及脑部缺血梗死灶(P<0.01),同时上调缺血半暗带中AR蛋白的表达(P<0.01),引起脑细胞凋亡增多及线粒体MPTP开放增加(均P<0.001);与WT-IR组相比,AR-/-+IR组神经功能评分、脑梗塞体积、细胞凋亡以及MPTP开放程度明显得到改善(均P<0.05)。与WT-IR组相比,WT-IR+ISO组神经功能评分和脑梗塞体积明显减少(均P<0.05),损伤侧脑组织中的AR蛋白的表达降低(P<0.01),损伤脑组织中的凋亡细胞以及MPTP开放程度减少(均P<0.001)。而对比AR-/-+IR组,AR-/-+IR+ISO组小鼠在神经功能评分、脑梗塞体积、凋亡细胞以及MPTP开放程度等方面差异无统计学意义。结论异氟醚能通过减少AR蛋白的表达,减轻线粒体功能损伤,从而改善小鼠脑缺血/再灌注损伤
新型嵌套折展子母网箱机构研究
网箱养殖是海洋设施养殖的重要战略方向,针对现有深海网箱难以自适应调整养殖区域以优化生态环境、体积庞大难以运输等问题,提出了新型嵌套折展子母网箱机构,以空间折展机构为网箱支撑母框架,嵌套安装于母框架的平面柔性折展机构为子网箱框架,以闭环钢丝绳驱动网箱折展。研究构成网箱框架机构的三重对称Bricard机构折展关键状态尺度约束类型的演变,揭示机构折展过程中对称面相交共线的几何不变特性,构造以对称面交线为折展轴线的网箱折展驱动机构;进一步建立网箱框架机构运动学方程,通过对称面几何投影解析求解驱动杆转角与网箱折展状态的对应关系。所提出的具有大折展比的嵌套折展网箱机构为深海网箱的研制提供了新思路
