818 research outputs found
The mechanism of Honokiol induced cancer cell apoptosis via AMPK/Nur77 signal pathway
AMPK是高度保守的细胞内能量感应器,它能通过抑制细胞增殖和生物合成过程响应细胞内能量应激。越来越多的研究表明,AMPK不仅是细胞能量平衡和代谢途径的主要调节因子,还与细胞凋亡和细胞自噬等过程有关。Nur77(也称为TR3/NGFI-B)是由立早基因NR4A1编码的孤儿核受体,是核受体超家族中的一员。Nur77能被激素、生长因子等诱导表达,参与细胞的生长、发育、增殖和凋亡等重要生理过程。 和厚朴酚是传统中药厚朴或凹叶厚朴中的主要活性成分之一。研究表明,和厚朴酚具有抗菌、抗炎、抗氧化、抗焦虑、抗血管生成和抗肿瘤等重要生理功能。和厚朴酚能够抑制多种肿瘤细胞生长,诱导细胞凋亡,和厚朴酚还能诱导肿瘤...AMPK is a highly conserved sensor of cellular energy status which can in response to energy stress by suppression of proliferation and biosynthesis of cancer cell. Research increasingly suggests that AMPK is not only a main regulator of cellular energy homeostasis and metabolic pathways, it’s also associated with apoptosis and autophagy of cancer cell. Nur77 is an orphan receptor coded by immediat...学位:理学硕士院系专业:药学院_化学生物学学号:3232013115338
A Research on R&D performance management in YY Software company
在政府大力提倡“大众创业,万众创新”的风气以及互联网+的趋势浪潮下,软件研发人才深受各行业企业欢迎。优秀的软件研发人才成为人才市场的香饽饽,也是各互联网公司或者创业公司重点从软件公司挖掘的对象,传统的软件企业研发势必面临优秀人才的流失、员工的积极性、组织的有效性等诸多问题。一套科学合理的绩效管理体系,不仅可以提高研发的整体水平,也能提高研发员工对于企业的认同感和归属感,降低人才流失,提高组织组织的有效性,从而为企业的发展、战略目标的落地和创新实现提供有效保障。 本文笔者从YY软件公司的当前研发人员绩效管理体系为研究起点出发,通过对绩效管理的国内外研究现状以及相关理论的收集、整理、分析和归纳,...In the government to vigorously promote the "popular entrepreneurship and innovation" and the trend of the Internet+, the software R&D personnel welcomed by the industry and enterprises.Especially,the excellent software R&D personnel to become very favorite, the Internet company and Startup company focus from the software company to hunt them, the traditional software enterprise R&D are facing the...学位:管理学硕士院系专业:管理学院_工商管理硕士(工商管理硕士)学号:1792013115075
Explanations of Momentum Effect and a Study of the Momentum Profits of Chinese Stock Returns
作为一种市场异象,惯性现象始终没有得到被广泛接受的解释,它目前已经成为维护有效市场假说的学者们眼中的一大难题,也成为支持行为金融理论的学者们自由发挥的阵地。鉴于国内文献中几乎找不到比较系统的关于惯性现象的文献综述,作者就自己的能力所及对惯性现象的理论解释做了一个综述。同时,本文就中国股市的惯性现象作了多角度的检验。在实证研究中,作者采用了四种惯性策略,并且将整个检验期间划分为两个时期进行检验。全文共分四章。第一章是导言。阐述了惯性现象研究的理论意义与实践意义、国内外研究现状、本文的研究思路、结构安排、创新与不足。第二章对惯性现象的理论解释进行综述。大量研究文献表明,惯性现象确实在全球范围内普遍...As one of the most hotly debated anomalies in the asset-pricing literature, the momentum effect presents one of the strongest challenges to the efficiency and rationality of financial markets. The scholars who maintain the market efficiency hypothesis have to face a difficult problem, and the scholars who support the behavioral finance have found a hot research field. In view of the fact that...学位:经济学博士院系专业:经济学院财政金融系_金融学(含保险学)学号:B19981202
新农村建设视角下的农村金融运行机制重构
党的十六届五中全会明确提出了建设社会主义新农村的宏伟目标。加快新农村建设,离不开金融的支持和服务。金融是现代经济的核心,没有现代农村金融,就不可能发展现代农业,就难以保证农业结构的调整、农民持续增收和农村社会的和谐。长期以来,由于对农村缺乏周密和
Design and Implementation of High-available Historical Mirror Image System of ERP System in Banks
随着国内银行业的国际化发展,为了满足资本市场对信息披露的要求,及时、准确、全面地披露财务报告信息,统一规范商业银行人、财、物等内部资源业务流程,降低操作风险,提高商业银行内部控制和内部管理水平,商业银行根据自身的整体战略目标和信息技术发展规划,商业银行结合自身的资源现况,实施ERP项目成为一种迫切需要。 在商业银行ERP系统运行以来,业务数据量增长较快,为保证银行数据能在ERP系统上健康、稳定高效的运行,商业银行需要对ERP系统进行优化,并进行历史数据和生产数据的剥离。在这个背景下设计开发了ERP系统的镜像系统,历史镜像系统核心部分由历史系统和镜像轮询调度组成,由商业银行、存储设备供应商HD...With the internationalization development of domestic banking industry, in order to satisfy the requirement of capital market to information disclosure , disclose the information of the financial reports prompt, accurately and comprehensively, standardize the business process of internal resources such as labors, finance and property in commercial banks, reduce operation risk, enhance the level...学位:工程硕士院系专业:软件学院_工程硕士(软件工程)学号:X200723000
Electrochemically shape-controlled formation of concave AuPd alloy nanoparticles on ITO substrate
运用电化学方波电位法, 在氧化铟锡(ITO)透明导电膜玻璃基底上实现AuPd纳米粒子的形状控制合成. 当固定方波下限电位0.30 V,; 上限电位分别为0.64和0.70 V时, 分别制备出内凹三八面体(TOH)和内凹六八面体(HOH) AuPd合金纳米粒子.; 运用扫描电镜(SEM)、X射线能量散射谱(EDX)和电化学循环伏安法表征所制备的纳米粒子, 结果表明所制备的AuPd纳米粒子在ITO上分散均匀,; 具有清晰的内凹三八面体和内凹六八面体的形状, Au:Pd元素比均接近3:1. 但由于Au比Pd的表面自由能低,; 导致Au在AuPd合金纳米粒子表面富集.发现从合成的TOH AuPd合金纳米粒子出发, 对其施加下限电位0.30 V、上限电位0.70; V的方波电位处理, 可实现由TOH向HOH形状转变; 延长方波电位处理时间仅改变AuPd合金纳米粒子的尺寸, 但HOH形状保持不变.Shape-control of AuPd alloy nanoparticles (AuPd NPs) substrated on; indium-tin oxide (ITO) was successfully achieved, for the first time, by; using electrochemical square-wave-potential (SWP) method. Concave; trisoctahedral AuPd alloy NPs (TOH AuPd NPs) and concave hexoctahedral; AuPd alloy NPs (HOH AuPd NPs) were prepared under SWP conditions with; lower potential of 0.3 V while different upper potentials of 0.64 and; 0.70 V, respectively. Different techniques including SEM, EDX and; electrochemical cyclic voltammetry were employed to characterize the; morphology and composition of AuPd alloy NPs. The results demonstrated; that the as-prepared TOH AuPd NPs and HOH AuPd NPs are uniform in shape; of correspondingly concave TOH and concave HOH, and are well dispersed; on the ITO substrate. The composition in terms of and Au:Pd atomic ratio; of both TOH and HOH AuPd alloy NPs is determined by EDX around 3:1.; However, a surface enrichment of Au on the AuPd NPs was observed, and is; ascribed to the lower surface energy of Au in comparison with that of; Pd. It has been found that, starting from the as-synthesized TOH AuPd; NPs, shape transformation from TOH to HOH can be accomplished by; applying a treatment of square wave with lower potential of 0.3 V and; upper potential of 0.7 V. Prolonging the treatment time results in; increasing the size of AuPd NPs, while the HOH shape is preserved.国家自然科学基
我国国有商业银行规模经济实证研究
我国国有商业银行资产规模在整个银行体系中占据了绝对地位,但是,国有银行整体的经营效率却远低于股份制商业银行,这与其在中国银行业中地位极不相符。如何扭转国有商业银行的经营效率,这已成了近几年银行业的一个重大课题,本文从考察四大国有银行1994-2004年间的规模经济状况出发,用Sur估计了我国国有商业银行的规模经济效应。实证结果显示,在样本期内,四大国有银行经历了从规模经济到规模不经济再逐渐接近到规模经济状态。这一研究结论将为我国国有商业银行后续的改革提供参考
Preparation and Characterization of Pt-Ni-SnO2/C for Ethanol Oxidation Reaction
采用改进的Bonnemann法成功制备了Pt/C、Pt-Ni_(1/3)/C、Pt-SnO_2/C、Pt-Ni_x-SnO_2/C(x =; 1/4, 1/3, 2/3,; 1)阳极电催化剂。利用X射线衍射(XRD)、高分辨透射电子显微镜(HR-TEM)以及X射线光电子能谱(XPS)对催化剂晶型结构、表面形貌和表面电; 子结构进行了表征。运用线性扫描伏安(LSV)和电流密度-时间(j-t)曲线进行电化学测试,研究了乙醇电催化氧化(EOR)活性。并用原位红外光谱(; in situ; FT-IR)研究了EOR过程中产物的分布。结果表明,Pt-Ni_(1/3)-SnO_2/C是由Pt-Ni合金和SnO_2两相组成。XPS结果表明; ,在Pt-SnO_2中添加微量的Ni,Pt表面电子结构发生了改变。电化学结果表明,三元催化剂的EOR活性均优于二元和纯Pt,其中Pt-Ni_(1; /3)-SnO_2/C的EOR活性最佳。Ni和SnO_2的加入并没有显著提高乙醇C-C键的断裂能力,但是二者的协同作用在低电位(0.1; V)下加强了乙醛的进一步氧化,生成了乙酸。A series of Pt/C, Pt-Ni-1/3/C, Pt-SnO2/C and Pt-Nix-SnO2/C (x = 1/4, 1/3, 2/3, 1) anode electro-catalysts have been synthesized by an improved Bonnemann method. The crystal structure, surface morphology and surface electronic structure were characterizated by X-ray diffraction (XRD), high resolution transmission electron microscope (HR-TEM) and X-ray photoelectron spectroscopy (XPS). The electro-catalytic activities were characterizated by linear sweep voltammetry (LSV) and amperometric current density-time (j-t) curve techniques for ethanol oxidation reaction (EOR). In situ spectroelectrochemical studies have been used to identity adsorbed reaction intermediates and products (in situ Fourier transform infrared spectroscopy, FT-IR). XRD and HR-TEM analysis revealed two phases in the ternary Pt-Ni-SnO2/C catalyst: Pt-Ni alloys and SnO2. XPS results show that the electronic structure of the Pt in Pt-Ni-1/3-SnO2/C might be changed due to the addition of Ni. The activity of Pt-Ni-SnO2/C for EOR was found to be higher than that of Pt/C, Pt-Ni/C and Pt-SnO2/C catalysts. The incorporation of Ni and SnO2 did not significantly improve C-C bond breaking for complete oxidation of ethanol, but the synergy under the low potential (0.1 V) to strengthen the further oxidation of acetaldehyde, generate the acetic acid.吉林省科技发展计划项目(20120741)和厦门大学固体表面物理化学国家重点实验室开放课题(201407)资
论国债与货币市场和资本市场的关系
论国债与货币市场和资本市场的关系黄志刚朱剑锋目前,国内理论界对国债与货币市场和资本市场的关系认识混乱。大部分人认为国债市场属于资本市场,因为资本市场包括中长期借贷市场和证券市场,而国债市场又是属于证券市场的(安体富、周升业,1996年)。也有人认为国..
PtNiSnO/C的制备、表征及其电催化氧化乙醇活性
采用改进的B?nnemann法成功制备了Pt/C、Pt-Ni/C、Pt-SnO/C、Pt-Ni-SnO/C(x=1/4,1/3,2/3,1)阳极电催化剂。利用X射线衍射(XRD)、高分辨透射电子显微镜(HR-TEM)以及X射线光电子能谱(XPS)对催化剂晶型结构、表面形貌和表面电子结构进行了表征。运用线性扫描伏安(LSV)和电流密度-时间(j-t)曲线进行电化学测试,研究了乙醇电催化氧化(EOR)活性。并用原位红外光谱(in situ FT-IR)研究了EOR过程中产物的分布。结果表明,Pt-Ni-SnO/C是由Pt-Ni合金和SnO两相组成。XPS结果表明,在Pt-SnO中添加微量的Ni,Pt表面电子结构发生了改变。电化学结果表明,三元催化剂的EOR活性均优于二元和纯Pt,其中Pt-Ni-SnO/C的EOR活性最佳。Ni和SnO的加入并没有显著提高乙醇C―C键的断裂能力,但是二者的协同作用在低电位(0.1 V)下加强了乙醛的进一步氧化,生成了乙酸。吉林省科技发展计划项目(20120741);厦门大学固体表面物理化学国家重点实验室开放课题(201407)资助~~
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