Relationship between polymorphism of fibroblast growth factor receptor 2 rs2981582 and susceptibility of breast cancer

目的探讨成纤维细胞生长因子受体2(fgfr2)基因rS2981582位点单核苷酸多态性(SnP)与乳腺癌易感性之间的关系。方法对193例乳腺癌患者和150例正常女性进行病例对照研究,采用dnA直接测序法同时检测其fgfr2基因第二内含子的SnP位点rS2981582的基因及基因型。结果乳腺癌患者fgfr2基因rS2981582位点的基因分布频率与正常女性相比,P>0.05;对该位点的基因分布频率与乳腺癌雌激素受体(Er)表达状态进行分析后发现,等位基因T的频率在Er阳性乳腺癌患者中为43.93%,在正常女性中为34.67%,两者相比,P 0.05).The gene frequency distribution and the expression of estrogen receptor(ER) in breast cancer were further analyzed.The minor allele T frequency of rs2981582 was 43.93% of cases whereas 34.67% of controls,the allele frequencies in the cases were significantly different from those of the controls(P < 0.05),the odds ratio(OR = 1.476) also showed a higher risk of breast cancer in individuals carrying the minor alleles.Conclusion The FGFR2 polymorphism rs2981582 C/T may contribute to the susceptibility of breast cancer with ER positive in Chinese women.国家自然科学基金资助项目(81173616); 福建省卫生厅青年科研课题(2009-2-78

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采用有性杂交和水稻成熟花粉辐照诱变育种技术相结合，选育出福建省第一个优质早籼稻品种“佳禾早占”。其产量水平 ４００～４５０ ｋｇ／６６７ｍ ２，高的 ５００ ｋｇ／６６７ ｍ２以上；稻米品质符合部颁优质食用米标准，经济效益好，是福建省主要推广的优质早稻新品种。福建省自然科学基金;; 农业科技项目资

对二维编织复合材料弹性、热、强度及失效分析模型的评论

纺织结构作为聚合物复合材料的增强相在许多工业应用中变得非常重要,例如在航海与航空领域中,由于其刚度及强度与其重量的高比值而倍受炊迎.由于工业及工程应用的需求,研究纺织复合材料的弹性性质及失效行为变得非常重要.这篇文章重点评论了关于二维编织复合材料弹性、热、强度及失效分析的数值及解析模型,给出了主要的建模技术及方法.同时也简单给出了编织复合材料从最初的一维模型到最近三维模型的发展.本文的目的不是对所论模型的数学方法进行详细分析,而是告知研究者关于先前工作的主要思想.这篇评论总共引用了122篇文献

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本发明属于物料配送技术领域，公开了一种车间环境下的多AGV协同调度方法及装置，所述方法包括：根据预先建立的全局地图和任务数据库进行加工任务分配，得到第一分配下车间内多个工位执行多个加工任务的加工总时间；所述加工总时间包括：多个AGV从当前工位到达下一工位的运输时间和多个工位的加工时间。根据工位的加工时间和运输时间对AGV进行路径规划，使路径规划后得到的第二分配的加工总时间最小，并以第二分配完成加工任务。有益效果：以加工时间和运输时间对AGV进行路径规划，可以减少AGV的停留等待工位加工的时间，避免AGV较长时间停留堵塞路径同时提高AGV的工作效率，进而提高系统的整体运行效率，降低加工总时间

A mechanical vibration identification method for sub-Nyquist sampling based on ESPRIT-like algorithm

This paper proposes a mechanical vibration identification method for sub-Nyquist sampling in theory, through the study on the ESPRIT algorithm. Then the method is improved for the problems encountered in the practical application: the big computational amount of solving generalized eigenvalues, the aggravation of ill-condition brought by correlation matrices, the big errors of attenuation coefficients. The improved identification method can be used to practically identify the sub-Nyquist sampling of mechanical vibrations. And the vibration signal identified can be recovered accurately. The validity of the method is verified through the simulation. &copy; 2014 IEEE

Breeding and Applicantion of Jiafuzhan——A New Breed of Early Indica Rice of High Quality

经过20多年的研究,采用自创的优质早籼稻新品种选育新途径,选育出大粒(千粒重30 g)优质、高产、稳产、抗病虫、适应性广的早籼稻新品种佳辐占.其品质基本上达到了部颁一级优质食用米标准,千粒重、长宽比、垩白度都是当前国内优质早籼稻品种中最好的品种之一.产量水平400~450 kg/667 m2,高产的超过500 kg/667 m2.广西、江西、广东等省、区已引种成功.2003~2004年在福建省推广11.4×104hm2,为农民增收2亿多元.该品种的育成,解决了水稻育种中长期存在的大粒不优质,早籼稻难优质,优质不高产,优质不抗病等难题.After 20 years' dedicated research under new technologies in breeding high-quality new-breed early indica Rice,Jiafuzhan has been successfully breeding.Its quality has almost reached A-level Editable Rice of Agriculture Department of China,and its average production reaches 400~450 kg/667m~2.with high yield production of 500 kg/667m~2.This new breed also has other characteristics such as enhanced resistance of blast and fallen,steady productivity and strong adaptability.Jiafuzhan has been put into production of over 11.4×10~4 hm~2 in Fujian Province and has been introduced and promoted in other provinces like Jiangxi,Guangdong and Guangxi.The successes of breeding Jiafuzhan is a solution to long existed problems in rice industry,such as low quality of big,grain rice and early indica rice,low productivity and poor blast resistance of high quality rice.农业部转化资金(02EFNZ16900762);; 福建省水稻育种攻关项目;; 福建省重大专项(2004NZ01-3);; 福建省三项费用(2000-Z-029);; 厦门市农业创新(3502Z20032007);; 国家后补助基金(2004年)资

空间引力波探测天文学的一个新窗口

本文内容分为两部分.第一部分通过外尔曲率来阐述引力波这个物理概念,为天体源引力波探测(地面或空间)建立一个基本的理论框架.第二部分中,在中国科学院二期先导研究的基础上,我们进一步地说明空间引力波探测的天文学意义,特别是在探索早期宇宙中星系结构的形成,星系-黑洞共同演化结构等重大天文问题中提供一种全新的观察窗口.简要介绍中国科学院空间引力波探测计划(太极计划)的任务设计,并进一步阐明其科学目标以及与(e)LISA项目的区别所在,最后给出空间任务中关键载荷的初步分析