Evaluation on difference of therapeutic efficacy of Jiawei Xiaoyao Granules and Pills in treatment of emotional disorder during perimenopause based on Greene Climacteric Scale

目的:在前期加味逍遥丸治疗围绝经期情绪障碍具有比较优势的基础上,基于grEEnE量表探讨其颗粒剂和丸剂不同剂型间疗效差异。方法:经筛选后患有情绪障碍的围绝经期女性75例随机等分为A、b、C3组,分别对应采用帕罗西汀、加味逍遥丸和加味逍遥颗粒剂治疗8周。所有患者在治疗前后各进行1次grEEnE及其子因子评定,并在观察期结束时进行TESS评定。结果:grEEnE总分差及其焦虑、抑郁因子分差:3种治疗方法均能改善,且相互间无显著差异;grEEnE性因子和血管因子分差:后二组均优于A组(P<0.01);TESS评分:与A组比较,b、C组均有统计学意义(P<0.01),评分均小于A组,且后二组间无显著差异。结论:加味逍遥的2种剂型间疗效无显著差异,考虑到帕罗西汀的不良反应,治疗该病加味逍遥的2种剂型都值得推荐。Objective: To investigate the difference in therapeutic efficacy between Jiawei Xiaoyao Granules and pills based on the preliminary research of treating emotional disorder during perimenopause with Jiawei Xiaoyao Pills and Greene Climacteric Scale.Methods: 75 female patients with emotional disorder during perimenopause were slected and randomly divided into 3 groups as group A, B and C.Patients in the 3 groups were treated with paroxetine, Jiawei Xiaoyao Pills and Jiawei Xiaoyao Granules respectively for 8 weeks.Greene and Greene factors assessment were carried out in all the patients before and after treatment, and the TESS assessment was carried out at the end of the observation period.Results: The three therapies all could improve the gap in total score of Greene and its factors as anxiety and depressed, and the difference among these three groups was no significant.The factors of Greene and gap in score of vascular factors of group B and C was better than that of group A(P<0.01).The difference in TESS score between group A and group B and C was significant(P<0.01), while the difference between group B and group C was not significant.Conclusion: The difference in curative effect between the two formulations was not significant.Because of the adverse reactions of paroxetine, in the treatment of emotional disorder during perimenopause, the two formulations of Jiawei Xiaoyao Powder were worth to be recommended.国家自然科学青年基金项目(No.81302960)~

Chlorofullerenes featuring triple sequentially fused pentagons

通讯作者地址: Tan,YZ(通讯作者),Xiamen Univ, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China 地址: 1. Xiamen Univ, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China 2. Xiamen Univ, Coll Chem & Chem Engn, Dept Chem, Xiamen 361005, Peoples R China 电子邮件地址: [email protected], [email protected] triple sequentially fused pentagons (TSFP) motif is one of the basic subunits that could be used for constructing fullerenes, but it violates the isolated pentagon rule (IPR) and has not been found in carbon cages to date. The properties of TSFP-incorporating fullerenes are thus poorly explored both theoretically and experimentally. Reported herein are four chlorinated derivatives of three different fullerene cages, all with the TSFP motif. X-ray crystallographic analyses indicate that the molecular strain inherent to the pentagon adjacency of a TSFP is significantly relieved upon exohedral chlorination, leaving one of the four pentagon fusion sites unsaturated and rendering the present derivatives chiral. This unique reactivity, in stark contrast to that of previously reported non-IPR fullerenes containing double fused pentagons or triple directly fused pentagons, can be rationalized by density functional theory calculations, and are expected to stimulate further studies of these new members of the fullerene family, both theoretically and experimentally.NNSF of China 20525103,20531050,20721001,20423002 20673088 973 Program 2007CB81530

l-序列的采样元素分布及k-错线性复杂度

证明了极大周期FCSR序列的任意采样序列在一个周期内0,1元素分布几乎平衡,利用这一分布性质研究了连接数为强2-素数的l-序列的k-错线性复杂度,结果显示这类l-序列具有非常稳定的线性复杂度

Анализ предпринимательских моделей перспективных для развития гостиничного бизнеса г. Владивостока : выпускная бакалаврская работа по направлению подготовки: 43.03.03 - Гостиничное дело

利用改进的可视化装置，研究了10°锥角的台锥型液相色谱柱内的谱带流型与柱参数变化的关系．将有机玻璃柱管加工成内圆台外方型的一体结构，选择折射率一致的色谱固定相硅胶和流动相环己烷，使整个色谱柱成为高度清晰的透明体，能直接观察柱中彩色样品谱带的动态三维流型．研究结果表明，在实验条件范围内，流动相流速对谱带流型无影响，填料的形状和性质对塞子状流型有一定程度的影响．比较了柱长为5cm和等比例放大后柱长为10cm锥型柱内的流型，发现放大后的锥型柱内仍然保持塞子状流型，总柱效等比例增加．表明继续按比例放大成为工业规模色谱柱后仍能保持塞子状流型

基于地统计学的土壤团聚体空间变异研究进展

团聚体是土壤基本结构单元,犹如生物体的细胞,深刻影响着土壤肥力和植物生长,并在土壤抗蚀性、土壤修复、全球碳汇效应等方面起着重要作用。过去研究多关注于土壤团聚体的微观形成过程与稳定机制。由于土壤特性、自然要素、人为活动等多因素共同驱动,团聚体的微观尺度分析并不能完全理解团聚体在生态系统中的作用与功能;同时,团聚体结构和稳定性具有高度空间异质性,传统的经典统计学方法难以反映真实状态下团聚体的空间格局,使得其研究方法逐渐过渡到地统计学。本文综述国内外基于GIS和地统计学的土壤团聚体空间变异性的研究现状,分析空间定量方法和尺度效应,总结团聚体空间变异的定量方法、影响因素、空间变异预测模型及其可视化方法,提出了当前研究存在的主要问题,展望了GIS和地统计学在土壤团聚体空间变异性中的研究前景。</p

Ｅｆｆｅｃｔｓ ｏｆ Ｔｏｐｏｇｒａｐｈｙ ａｎｄ Ｌａｎｄ Ｕｓｅ ｏｎ Ｓｐａｔｉａｌ Ｄｉｓｔｒｉｂｕｔｉｏｎ ｏｆ

地形和土地利用方式对土壤无机碳(SIC)的空间分布和碳汇效应有重要影响。以黄土高原丘陵沟壑区纸坊沟小流域为对象,研究土地利用、地形对0-200cm土层内SIC空间分布的影响。结果表明,地形对纸坊沟流域SIC空间分布呈极显著影响(P&lt;0.01),表现为峁顶(15.32g/kg)&gt;坡地(14.45g/kg)&gt;沟底(12.27g/kg)的变化趋势;土地利用方式影响该流域SIC分布,其含量表现为灌木地&gt;草地&gt;林地&gt;农地,其中灌木地极显著高于林地、草地和农地,林地和草地极显著高于农地,而林地与草地无显著差异;地形与土地利用交互作用极显著影响SIC空间分布(P&lt;0.01)。相关结果可为黄土高原土壤碳库提供基础数据,有助于明确黄土高原在中国陆地碳循环中的作用。Ｉｔ　ｉｓ　ｓｉｇｎｉｆｉｃａｎｔ　ｔｏ　ａｃｃｕｒａｔｅｌｙ　ａｓｓｅｓｓ　ｒｅｇｉｏｎａｌ　ｓｐａｔｉａｌ　ｄｉｓｔｒｉｂｕｔｉｏｎ　ｃｈａｒａｃｔｅｒｉｓｔｉｃｓ　ａｎｄ　ｉｎｆｌｕｅｎｃｉｎｇｆａｃｔｏｒｓ　ｏｆ　ｓｏｉｌ　ｉｎｏｒｇａｎｉｃ　ｃａｒｂｏｎ　ａｎｄ　ｔｏ　ｓｔｕｄｙ　ｅｆｆｅｃｔｓ　ｏｆ　ｌａｎｄ　ｕｓｅ　ａｎｄ　ｔｏｐｏｇｒａｐｈｉｅｓ　ｏｎ　ｓｐａｔｉａｌ　ｄｉｓｔｒｉｂｕｔｉｏｎ　ｏｆ　ｓｏｉｌｉｎｏｒｇａｎｉｃ　ｃａｒｂｏｎ．Ｔａｋｉｎｇ　Ｚｈｉｆａｎｇｇｏｕ　ｓｍａｌｌ　ｗａｔｅｒｓｈｅｄ，ｗｈｉｃｈ　ｉｓ　ｓｉｔｕａｔｅｄ　ｉｎ　ｌｏｅｓｓ　ｈｉｌｌｙ－ｇｕｌｌｙ　ｒｅｇｉｏｎ，ａｓ　ａｎｏｂｊｅｃｔ，ｉｎｆｌｕｅｎｃｅｓ　ｏｆ　ｌａｎｄ　ｕｓｅ　ａｎｄ　ｔｏｐｏｇｒａｐｈｉｃ　ｏｎ　ｔｈｅ　ｄｉｓｔｒｉｂｕｔｉｏｎ　ｏｆ　ｉｎｏｒｇａｎｉｃ　ｃａｒｂｏｎ　ｏｎ　０－２００ｃｍ　ｓｏｉｌ　ｌａｙｅｒｗｅｒｅ　ｓｔｕｄｉｅｄ．Ｒｅｓｕｌｔｓ　ｓｈｏｗｅｄ　ｔｈａｔ　ｔｈｅ　ｔｅｒｒａｉｎ　ｈａｄ　ａ　ｓｉｇｎｉｆｉｃａｎｔ　ｉｎｆｌｕｅｎｃｅ　ｏｎ　ｔｈｅ　ｓｐａｔｉａｌ　ｄｉｓｔｒｉｂｕｔｉｏｎ　ｏｆ　ｓｏｉｌｉｎｏｒｇａｎｉｃ　ｃａｒｂｏｎ　ｏｎ　Ｚｈｉｆａｎｇｇｏｕ　ｓｍａｌｌ　ｗａｔｅｒｓｈｅｄ，ａｎｄ　ｒａｎｇｅｄ　ａｓ：Ｔａｂｌｅ　ｌａｎｄ（１５．３２ｇ／ｋｇ）＞ｓｌｏｐｅ　ｌａｎｄ（１４．４５ｇ／ｋｇ）＞ｇｕｌｌｙ　ｌａｎｄ（１２．２７ｇ／ｋｇ）．Ｔｈｅｒｅ　ｗｅｒｅ　ｄｉｆｆｅｒｅｎｃｅｓ　ｉｎ　ｔｈｅ　ｄｉｓｔｒｉｂｕｔｉｏｎ　ｏｆ　ｓｏｉｌ　ｉｎｏｒｇａｎｉｃ　ｃａｒｂｏｎ　ｕｎｄｅｒｄｉｆｆｅｒｅｎｔ　ｌａｎｄ　ｕｓｅ．Ｓｏｉｌ　ｉｎｏｒｇａｎｉｃ　ｃａｒｂｏｎ　ｃｏｎｔｅｎｔ　ｉｎ　ｓｈｒｕｂ　ｌａｎｄ　ｗｅｒｅ　ｓｉｇｎｉｆｉｃａｎｔｌｙ　ｈｉｇｈｅｒ　ｔｈａｎ　ｔｈｏｓｅ　ｉｎ　ｗｏｏｄｌａｎｄ，ｇｒａｓｓｌａｎｄ　ａｎｄ　ｆａｒｍｌａｎｄ，ｗｏｏｄ　ｌａｎｄ　ａｎｄ　ｇｒａｓｓｌａｎｄ　ｓｉｇｎｉｆｉｃａｎｔｌｙ　ｈｉｇｈｅｒ　ｔｈａｎ　ｔｈｏｓｅ　ｉｎ　ｆａｒｍｌａｎｄ．Ｂｕｔ　ｔｈｅｒｅｗｅｒｅ　ｎｏ　ｓｉｇｎｉｆｉｃａｎｔ　ｄｉｆｆｅｒｅｎｃｅ　ｂｅｔｗｅｅｎ　ｗｏｏｄ　ｌａｎｄ　ａｎｄ　ｇｒａｓｓｌａｎｄ，ａｎｄ　ｓｏｉｌ　ｉｎｏｒｇａｎｉｃ　ｃａｒｂｏｎ　ｃｏｎｔｅｎｔ　ｕｎｄｅｒｄｉｆｆｅｒｅｎｔ　ｌａｎｄ　ｕｓｅ　ｃｏｕｌｄ　ｂｅ　ｏｒｄｅｒｅｄ　ａｓ　ｆｏｌｌｏｗｓ：Ｓｈｒｕｂ　ｌａｎｄ＞ｇｒａｓｓｌａｎｄ＞ｗｏｏｄｌａｎｄ＞ｆａｒｍｌａｎｄ；ｉｎｔｅｒａｃｔｉｏｎ　ｏｆｔｏｐｏｇｒａｐｈｉｃ　ｐｏｓｉｔｉｏｎ　ａｎｄ　ｌａｎｄ　ｕｓｅ　ｓｉｇｎｉｆｉｃａｎｔｌｙ　ａｆｆｅｃｔｅｄ　ｔｈｅ　ｓｐａｔｉａｌ　ｄｉｓｔｒｉｂｕｔｉｏｎ　ｏｆ　ｓｏｉｌ　ｉｎｏｒｇａｎｉｃ　ｃａｒｂｏｎ（Ｐ＜０．０１）．Ｔｈｅ　ｒｅｓｕｌｔ　ｃａｎ　ｐｒｏｖｉｄｅ　ｂａｓｉｃ　ｉｎｆｏｒｍａｔｉｏｎ　ｆｏｒ　ｓｏｉｌ　ｃａｒｂｏｎ　ｐｏｏｌ　ｏｆ　ｔｈｅ　Ｌｏｅｓｓ　Ｐｌａｔｅａｕ，ｉｔ　ｉｓ　ｈｅｌｐｆｕｌ　ｔｏｋｎｏｗ　ｔｈａｔ　ｔｈｅ　Ｌｏｅｓｓ　Ｐｌａｔｅａｕ　ｗｈｉｃｈ　ｉｓ　ｉｍｐｏｒｔａｎｔ　ｔｏ　ｃａｒｂｏｎ　ｃｙｃｌｅ　ｏｆ　ｔｅｒｒｅｓｔｒｉａｌ　ｅｃｏｓｙｓｔｅｍｓ　ｏｆ　Ｃｈｉｎａ

XPS study on birnessites with different average oxidation states

为了了解水钠锰矿八面体空位的具体分布状况以及表面化学性质,采用X线光电子能谱技术(XPS)对不同锰氧化度水钠锰矿表面Mn与O元素的化学状态进行研究;探讨水钠锰矿结构中空位的分布状况,并建立结构模型。研究结果表明:在高真空测试环境下,在不同锰氧化度水钠锰矿结构中,Mn存在饱和配位和不饱和配位2种化学状态,其含量(摩尔数分数,下同)分别为83.79%~91.69%和8.31%~17.21%;对于锰氧化度较高的水钠锰矿,不饱和配位Mn的含量较小;O以晶格氧、羟基氧和水分子中氧3种化学状态存在,其含量分别为50.44%~65.05%,24.90%~39.27%和8.07%~12.63%;对于锰氧化度较高的水钠锰矿,结构中羟基氧的含量较大;当水钠锰矿沿(110)方向上含Mn3+的MnO6八面体链中Mn3+含量增大时,结构中空位含量相应减少。 更多还原<br /