476 research outputs found

    Design and Implementation of Highway Management Information System Based on J2EE

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    随着中国经济的飞速发展,中国在交通领域实现了突破性的进展,高速公路基础设施建设进程也加快,不仅是对于路网的建设有着更加全面的提升,在服务方面也有着很大的完善,主干线的建设也开始了不断改善。不过,正是因为高速公路逐渐增多,相应的交通事故也越来越频繁,加强路政的管理迫在眉睫。但是,传统的路政管理已经无法满足如今的社会需要,传统的路政管理手段明显落后,大量的信息也导致通过传统的管理方法不能及时处理,以致各部门不能及时做出针对性决策。因此,目前迫切需要引进高速公路路政管理系统来对高速公路的路政进行管理,只有通过信息技术才能满足现在路政需求。 本系统设计框架基于J2EE开发框架之上进行开发,集合B/S...With the rapid development of Chinese economy, China in the transport sector to achieve a breakthrough, highway infrastructure construction process has accelerated, not only for the construction of road network has a more comprehensive upgrade, the service also has a great improvement , the construction of the main route also started improving.However, precisely because of the gradual increase in ...学位:工程硕士院系专业:软件学院_工程硕士(软件工程)学号:X201323111

    A Study on the competition strategy of S depot Company

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    摘要 近年来厦门堆场行业已经出现了群雄混战的局面,竞争日趋白热化。同时2008年爆发的全球金融危机给海运行业带来的巨大冲击,已经迅速威胁到堆场行业自身的生存和发展。作为S公司的重要组成部分,在新形势下S堆场公司如何生存和发展,并配合母公司实现其战略目标,这要求公司迅速摸索出一条适合自身发展的竞争战略。 本文以“S堆场公司的竞争战略研究”为题,运用竞争战略的理论和方法,借助PEST分析、五力模型、价值链分析、BCG矩阵分析、SWOT分析和战略钟模型等分析工具,对S堆场公司所面临的外部环境以及内部资源与能力进行详细的分析。在如何配合母公司完成其战略目标的情况下,确立适合自身的发展战略,在此基础...ABSTRACT In recent years, Xiamen depot industry sees a fiercer and fierce competition among companies. Meanwhile the global financial crisis started in 2008 is bringing a great impact to the sea shipping industry and has threatened the depot industry survival and development. As an important component of S company, S depot company needs to find out how to survive and develop under the new circums...学位:工商管理硕士院系专业:管理学院高级经理教育中心(EMBA项目)_高级管理人员工商管理硕士(EMBA)学号:X200715602

    A Study on the Impact of Corporate Social Performance on Corporate Financial Performance——Based on the Sample of China Listed Companies in Manufacturing Sector

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    现代企业社会责任的思想形成于20世纪初,上世纪七十年代以来,关于企业社会绩效与财务绩效关系的实证研究逐渐成为企业社会责任研究的焦点。本文致力于探索我国企业社会绩效对财务绩效的影响机制,为我国企业社会责任实践提供经验支持。 本文先对过去四十多年的研究进行了综述,发现国内外关于企业社会绩效对财务绩效影响的实证研究已经非常丰富,主要有三个结论:正相关、负相关和不相关,其中大部分的研究支持正相关的结论,认为负相关和不相关的研究都相对较少,但不同实证间的研究方法和样本来源都各不相同,互相之间缺乏可比性,因此本文接下来分析了现有研究的问题并提出相应的改进思路。 在此基础上,本文从利益相关者理论入手...Contemporary corporate social responsibility thought was formed at the beginning of the 20th century. Since 1970s, the empirical research on the relationship between corporate social performance(CSP) and financial performance(CFP) has gradually become the focus on the study of corporate social responsibility. This article is dedicated to explore the mechanism of how CSR affects CFP, so as to provi...学位:经济学硕士院系专业:经济学院_管理经济学学号:1532010115200

    城市贫困群体的社会分裂与融合

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    本文从贫困群体文化的角度分析了我国的城市贫困问题。文章认为 ,由于我国城市贫困人口缺乏就业机会 ,开始出现长期化和相对固定化的趋势 ,具有较强的贫困群体意识 ,他们正逐渐从主流社会中脱离出来 ,表现出了与社会分裂的趋势。因此 ,从有利于城市贫困群体社会融合的角度出发 ,城市反贫困应注重采取的措施是社会救助要体现“以人为本”的宗旨 ,要为城市贫困人口提供更多的就业机会 ,在难以提供更多就业机会的情况下实施“准就业” ,以社区建设促进城市贫困群体的社会融合

    中国国有企业改革与发展研究

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    国企改革是中央实施做强做大国有企业方针的重大战略步骤,推进国有企业改革,要有利于国有资本保值增值,有利于提高国有经济竞争力,有利于放大国有资本功能。所以研究中国国有企业改革与发展是社会主义的题中之意,本文主要剖析国企改革的历史进程,以及国有企业改革存在的问题,并提出相应的措施

    pJAK2 polypeptide,an antagonist of suppressors of cytokine signaling-1,can enhance the antitumor effect of dendritic cells

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    目的:探讨细胞因子信号转导抑制因子-1(SuPPrESSOrS Of CyTOkInE SIgnAlIng1,SOCS1)拮抗物PJAk2多肽(氨基酸序列号为1001-1013)参与树突状细胞(dEndrITIC CEllS,dCS)的体外诱导培养后对dCS抗肿瘤作用的影响。方法:采集健康人外周血,离心获得单个核细胞,用重组人粒细胞巨噬细胞集落刺激因子(rECOMbInAnT HuMAn grAnulOCyTE-MACrOPHAgE COlOny STIMulATIng fACTOr,rHgM-CSf)及重组人白细胞介素-4(rECOMbInAnT HuMAn InTErlEukIn-4,rHIl-4)诱导dCS,第5天分为4组:单纯dCS培养(对照)组、抗原负载(lySATE-dCS)组、多肽修饰(PJAk2-dCS)组和抗原与多肽共培养(lySATE+PJAk2-dCS)组,第6天各组加入肿瘤坏死因子-α(TuMOr nECrOSIS fACTOr-AlPHA,Tnf-α)促成熟。倒置显微镜下观察dCS形态;fCM法检测dCS表型;乳酸脱氢酶(lACTATE dEHydrOgEnASE,ldH)细胞毒实验检测各组细胞毒性T淋巴细胞(CyTOTOXIC T lyMPHOCyTE,CTl)对胃癌细胞bgC-823的靶向杀伤作用;ElISA法检测白细胞介素-12(InTErlEukIn-12,Il-12)和γ干扰素(InTErfErOn-γ,Ifn-γ)的水平。结果:与未加入诱导剂组相比,各组均成功诱导出成熟dCS,均高表达Cd80、Cd83、Cd86和人类白细胞dr抗原(HuMAn lEukOCyTE AnTIgEn dr,HlA-dr),但以lySATE+PJAk2-dCS组的表达水平最高。在10:1~30:1的效靶比范围内,CTl杀伤作用与效靶比呈正相关。当效靶比为30:1时,对照组的CTl杀伤率达(19.77±2.34)%,低于其他3组(P<0.01),而lySATE+PJAk2-dCS组较lySATE-dCS组及PJAk2-dCS组都高(P<0.05)。lySATE+PJAk2-dCS组培养上清液中Il-12及Ifn-γ的分泌水平明显高于对照组(P<0.01)。结论:SOCS1拮抗物PJAk2多肽(1001-1013)可增强dCS对胃癌细胞的抗原递呈及特异性抗肿瘤作用。Objective:To investigate the effect of pJAK2 polypeptide,an antagonist of SOCS1(suppressors of cytokine signaling 1),on antitumor effect of in vitro cultivation-induced DCs(dendritic cells).Methods:Peripheral blood was collected from the healthy volunteers,and the PBMCs(peripheral blood mononuclear cells)were isolated.DCs were induced by rhGM-CSF(recombinant human granulocyte-macrophage colony-stimulating factor)and rhIL-4(recombinant human interleukin-4).On the fifth day,DCs were divided into four groups:control group,Lysate-DCs group,pJAK2-DCs group,and Lysate + pJAK2 DCs group.On the sixth day,TNF-α(tumor necrosis factor-alpha)was added into each group.The morphological features of DCs were observed under an inverted microscope;the phenotypes were detected by FCM(flow cytometry);the killing effect of CTLs(cytotoxic T lymphocytes)on gastric cancer BGC-823 cells was evaluated by LDH(lactate dehydrogenase)cytotoxicity test;the concentrations of IL-12(interleukin-12)and IFN-γ(interferon-γ)were detected by ELISA(enzyme-linked immuno sorbent assay).Results:Mature DCs presented typically morphological and phenotypic features;the DCs in Lysate + pJAK2-DCs group had the highest expression levels of CD80,CD83,CD86 and HLA-DR(human leukocyte antigen DR).When the ratio of effectors to target cells ranged from 10:1 to 30:1,the killing activity of CTLs had a positive correlation with the ratio.When the ratio of effectors to target cells was 30:1,the killing activity of CTLs in the control group was(19.77±2.34)%,which was lowest as compared with the other groups(P < 0.01),meanwhile the killing activity of CTLs in Lysate + pJAK2-DCs group was higher than those in Lysate-DCs and pJAK2-DCs groups(P < 0.05).The levels of IL-12 and IFN-γ secretion in Lysate + pJAK2-DCs group were apparently higher than those in the control group(P < 0.01).Conclusion:An antagonist of SOCS1,pJAK2 polypeptide,can enhance the ability of antigen presentation and specific antitumor effect of DCs on gastric cancer cells.南京军区医学科技创新课题资助项目(编号:10MA068); 福建省自然科学基金面上项目(编号:2010D013); 厦门市科技计划创新项目(编号:3502z20104014

    浅论我国投资中的中央银行宏观参与

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    一、中央银行在投资中所能控制的是投资需求投资的含义不仅指新建项目本身,而且指将货币转化为资本以取得利润的行为.因此,投资需求的增减反映在货币上就是货币量的增减。投资引起的货币量增减对社会经济生活的影响有下述几种情况:第一,在投资需求增加引起的社会总需求的增加与潜在的生产要素相适应的情况下,投资需求的增加则导致社会生产的发展,实际产出增加,市场商品供给量增加,而不会对物价水平产生太大的影响.第二,在投资需求增加所引起的社会总需求的增加量超过了潜在的生产要素量的情况下,投资需求增加,一方面会引起生产的发展,实际产出的增加;另一方面则会引起物价水平的上涨
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