Advances in Preparation, Physicochemical Properties and Applications of Heteroatom-Doped Graphene Quantum Dots

发光石墨烯量子点(grAPHEnE QuAnTuM dOTS,gQdS)的良好理化性能引起许多领域研究人员的关注,但其荧光量子产率不高、活性位点相对较少、选择性较差等缺陷限制了它在分析传感领域的应用。异原子掺杂gQdS可以在一定程度上解决这些问题。本文介绍了异原子掺杂gQdS的制备方法、理化性质和应用情况,并对异原子掺杂gQdS的发展和应用前景进行分析和展望。Luminescent graphene quantum dots( GQDs) display excellent physicochemical properties,which have ignited tremendous and increasing research interest of researchers from different fields.However,there are still some limitations including lowquantum yield,less active sites and unsatisfactory selectivity,which impede their wide applications.As research continues,doping GQDs with heteroatoms has been considered as an effective strategy to address the above problems.In this review,we summarize the preparation methods,physicochemical properties and applications of heteroatom-doped GQDs.There are two kinds of heteroatom-doped GQDs including single-doped GQDs( B,N,S,F,Cl,et al.) and co-doped GQDs( B,N or N,P or N,S co-doping).The introduced heteroatoms changed the charge density and charge distribution of the GQDs,resulting in the enhancement of fluorescence quantum dots,more active sites and the appearances of new physicochemical properties including electrocatalytic activity and intrinsic peroxidase-like catalytic activity.We also give a perspective on the subsequent development and promising applications of heteroatom-doped GQDs.国家自然科学基金项目(No.21375112); 厦门市科技局高校创新项目(No.3502Z20143025)资助~

子宫内膜癌雌孕激素受体与临床病理分析

【目的】探讨子宫内膜癌雌激素受体(ER)、孕激素受体PR)与临床、病理间的关系。【方法】对83 例子宫内膜癌 患者手术标本常规进行病理检查, 同时采用免疫组化技术检测ER、PR。【结果】子宫内膜癌组织ER、PR 及ER 和PR 同时阳 性率较高, 分别为56.6%、81.9 %、53.0 %。绝经前子宫内膜癌组织ER、PR 阳性率高于绝经后(P <0.05)。子宫内膜癌Ⅰ 期 ER、PR 阳性率高于Ⅱ 期以上者(P <0.05)。子宫内膜癌组织高分化的ER 阳性率高于中低分化(P <0.05), 而PR 阳性率 与组织分化程度相关不大(P >0.05)。【结论】子宫内膜癌ER、PR 阳性表达与手术病理分期、分化程度有关, 对指导术后内 分泌治疗有一定价值

Morphological Characteristics of Atmospheric Aerosols with Different Sizes in Xiamen During Autumn

应用场发射扫描电镜(fESEM)研究了厦门城区秋季(2013年11月)不同粒径大气颗粒物的微观形貌及其元素组成特征.结果表明,厦门城区的大气颗粒物主要有烟尘集合体、飞灰颗粒、矿物颗粒、生物颗粒等.在粗粒径范围(>2.5μM),不规则矿物颗粒占多数,主要来自路面或建筑扬尘;细粒径颗粒物(2.5μm),mainly originating from road dust and construction dust.The composition of fine particles(<1.0μm)were mainly sulphates and nitrates.Soot aggregates and fly ashes almost appeared in every scope of sizes of aerosols,indicating that fine particles discharged from combustion evolved from small sizes to big ones because of agglomeration.All these features indicated that the particles mainly originated from fossil fuel burning,motor vehicle particles,dusts over the Xiamen City in autumn 2013,and much attention should be paid to control air pollution.国家自然科学基金(41171365;40971257); 厦门大学山海基金(2013SH011