Properties and Applications of Osmium Metallapentalynes and Metallapentalenes

2013年，本课题组报道了一类全新的金属杂芳香化合物——金属杂戊搭炔 合成。金属杂戊搭炔反应性丰富，可利用多种衍生化反应构筑一系列结构多样、 性能各异的金属杂戊搭炔/烯类化合物。本论文系统研究了金属杂戊搭炔/烯类化 合物的光学、电化学性能，并从中筛选出性能优越的化合物，进行光声成像、光 热治疗以及光动力学治疗等应用的初探。本论文共分为以下五章： 第一章是绪论，结合本论文的核心内容，简要介绍了金属杂戊搭炔/烯化合 物的合成与性能、光声成像、光热治疗、光动力学治疗等内容。此外，简述了本 论文设想和目的。 第二章研究了金属杂戊搭炔/烯化合物的光学性能，结合理论计算，解释了 化合物的...In 2013, we reported a kind of brand new metallaaromatics, i.e. metallapentalynes. Metallapentalynes are highly reactive and a series of metallapentalynes as well as metallapentalenes could be readily obtained by its derivatization. In this dissertation, we investigated the spectral properties and electrochemical performance of the metalla-aromatics...学位：理学硕士院系专业：化学化工学院_高分子化学与物理学号：2052013115168

Measurement of the Static Optoelectronic Characteristics of InGaAs/InP Avalanche Photodiode

建立了雪崩二极管的静态光电特性的自动测试系统。利用该系统对光敏面的直径为500μm的台面型InGaAs/InP雪崩光电二极管(APDs)进行测试。测试结果表明,该APD器件在90%击穿电压下的暗电流为151nA,在直径500μm的光敏面上其光响应均匀性良好。提出一种测量雪崩二极管倍增因子的方法,只需利用普通的测量电流-电压的测试仪器,就可以获得开始倍增时的光电流,从而得到APD的倍增因子。通过该方法得到的InGaAs/InPAPD器件最大倍增因子的典型值在10～100量级。A measurement system is set up which could measure static optoelectronic characteristics of avalanche photodiodes (APDs). By using this system, the mesa-structure InP/InGaAs APDs is measured. The results show that the APDs have a relatively low dark current (～150 nA at 90% of breakdown) and a uniform photoresponse profile of about 500 μm diameter. A method of getting APDs's multiplication gain is also proposed. Through getting the photocurrent at the point where multiplication is beginning, the multiplication gain can be obtained by the simple current-voltage equipment. For InP/InGaAs APDs, the typical maximum multiplication gain measured by this method is about 10～100

基于内毒素血症探讨皂术茵陈方对非酒精性脂肪性肝炎大鼠的影响

目的 基于内毒素血症探讨皂术茵陈方防治非酒精性脂肪性肝炎(NASH)大鼠的影响及其作用机制。方法 采用随机数字表法将40只大鼠分为5组,即正常组、模型组、皂术茵陈方组、盐酸吡格列酮组及培菲康组,每组8只。除正常组外,其余32只大鼠采用高脂饮食16周建立大鼠NASH模型,在造模第9周开始,皂术茵陈方组给予皂术茵陈方水提液60 mg/(kg·d)灌胃,盐酸吡格列酮组给予盐酸吡格列酮10 mg/(kg·d)灌胃,培菲康组给予培菲康210 mg/(kg·d)灌胃,正常组及模型组均给予双蒸水10 mL/(kg·d)灌胃,共治疗8周。第16周末经腹主动脉取血,生化法检测肝组织甘油三酯(TG)水平,苏木精—伊红(HE)染色观察肝组织病理学变化。终点显色法检测血浆内毒素(LPS)含量。ELISA法检测肝组织肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-1β、IL-6等炎症因子的表达水平。结果 与正常组比较,模型组大鼠肝组织显示出典型的NASH组织学特征,出现重度脂肪变性,不同程度的炎细胞浸润和坏死灶。大鼠肝湿重、肝指数、肝脏TG含量、血浆LPS水平、肝组织TNF-α、IL-1β、IL-6等炎症因..

CCCCC pentadentate chelates with planar Möbius aromaticity and unique properties

本课题充分发挥了厦门大学多学科协同研究优势，通讯作者为夏海平教授（合成、表征）、刘刚教授（生物医学应用）和吕鑫教授（理论计算）。合成实验和结构表征由朱从青（第一作者，目前在麻省理工学院、2005年诺贝尔化学奖得主Richard Schrock教授课题组从事博士后研究）完成；生物医学应用由杨彩霞（共同第一作者）、林凎、杨宇惠、王晓勇合作完成；理论计算由朱军、王永恒、朱从青完成。美国NIH的陈小元教授参与了生物医学应用的讨论。该研究工作得到国家自然科学基金委、科技部项目的支持。The coordinating atoms in polydentate chelates are primarily heteroatoms. We present the first examples of pentadentate chelates with all binding atoms of the chelating agent being carbon atoms, denoted as CCCCC chelates. Having up to five metal-carbon bonds in the equatorial plane has not been previously observed in transition metal chemistry. Density functional theory calculations showed that the planar metallacycle has extended Craig-Möbius aromaticity arising from 12-center–12-electron dπ-pπ π-conjugation. These planar chelates have broad absorption in the ultraviolet-visible–near-infrared region and, thus, notable photothermal performance upon irradiation by an 808-nm laser, indicating that these chelates have potential applications in photothermal therapy. The combination of facile synthesis, high stability, and broad absorption of these complexes could make the polydentate carbon chain a novel building block in coordination chemistry.the National Basic Research Program of China (nos. 2012CB821600 and 2014CB744503) , the National Science Foundation of China (nos. 21332002, 81422023, 51273165, 21490573, and 21573179)

Effect of laser dispersed treated morphology on traction coefficient under mixed lubrication

To investigate the influence of surface texture on traction characteristics of wheel/rail under mixed lubrication, laser dispersed treatment was used to form texture patterns, such as longitudinal, transverse and rhombus, on the surface of wheel discs. The film thickness and contact area ratio were calculated by using deterministic model instead of stochastic model. Based on the load-sharing concept, the hydrodynamic film and asperities both contribute in carrying the total load. Therefore the traction force is composed of two components: hydrodynamic traction force and asperity traction force. The tribological tests were conducted on an Amsler type wear testing machine. It is shown that the traction coefficient of rhombus pattern is higher than that of longitudinal and transverse, while the latters are similar. Though the asperity orientation of longitudinal and transverse is different, their influence on traction coefficient under mixed lubrication should be investigated further. © Civil-Comp Press, 2014

Comparison study of infantile tuina between LI Dexiu and LIU Kaiyun

以《李德修小儿推拿秘笈》和刘开运《小儿推拿疗法》为蓝本,研究两者在操作手法、穴位考订以及治疗原则方面的异同点,为李德修与刘开运小儿推拿的更好推广应用提供理论依据。With esotericaof Infantile Tuina by LI Dexiu and Infantile Tuina Therapy of LIU Kaiyun,the differences and similarities of manipulations,acupoints and the principles of treatment were studied so as to provide theoretical evidence to popularize tuinaof LI Dexiu and LIU Kaiyun

实用化GaInP-AlGaInP半导体量子阱可见光激光器

用低压MOVPE方法研制出了波长为655nm与670nm的GaInP-AIGaInP半导体量子阱可见光激光器，并已形成一定的批量生产能力。器件的阈值电流典型值为45mA，输出光功率不小于5mW，最高工作温度不低于50℃，预计20℃时寿命接近100000小时，主要技术指标与目前进口的同类产品水平相当，完全可以满足实用要求

InGaAs／InPAPD探测器光电特性检测

建立了雪崩二极管的静态光电特性的自动测试系统．利用该系统对光．敏面的直径为500岬的台面型InGaAs/InP雪崩光电二极管（APDs）进行测试．测试结果表明，该APD器件在90％击穿电压下的暗电流为151nA，在直径500μm的光敏面上其光响应均匀性良好．提出一种测量雪崩二极管倍增因子的方法，只需利用普通的测量电流一电压的测试仪器，就可以获得开始倍增时的光电流，从而得到APD的倍增因子．通过该方法得到的InGaAs／InPAPD器件最大倍增因子的典型值在10-100量级