ポストコロナジダイ ニ オケル ヨコレンケイ キョウカガタ コクサイ コウリュウ カツドウ ノ テンカイ タヨウナ ブンカ ゲンゴケン カラ ノ リュウガクセイ リクルート ヲ ソクシン スル オオサカダイガク バーチャル ダイガク ツアー ノ ジッセン

新型コロナウイルス感染症拡大等により，全世界で海外留学を取り巻く環境が激変している．多種多様なオンラインイベント，膨大な情報やオンラインコミュニティを選択できる環境におかれている留学希望者及び大学の需要に合わせて，新たなプログラムの企画と開発が必要になっている．大阪大学は2020年春よりオンライン留学説明会を企画，実施し，また大学のブランディング活動を継続しつつ，バーチャル留学プログラムを設立することにより，バーチャルおよび対面での国際学生交流活動を企画，開催してきた．大阪大学は，新たに展開したこれらの活動と，留学生の応募と入試に関するサポート，就職指導と支援なども組入れ，留学生のオンラインリクルート体制を構築した．本稿では，大学の国際化促進フォーラムの幹事校として，大阪大学が主催した「多様な文化・言語圏からの留学生リクルート：バーチャル大学ツアーの実施」の企画背景，実践事例と今後の展開方向について紹介する．大阪大学はこれまでの経験を活かし，ポストコロナを見据えた留学生のリクルート戦略としてバーチャル大学ツアーを開催し，ニューノーマルにおけるオールジャパンでの留学生リクルートの促進を図り，協力体制の構築に貢献した．本稿の目的は，このプロジェクトの実施成果と課題を分析し，横連携強化型国際交流活動の更なる発展の可能性を展望することである．The global circumstances surrounding international student recruitment and study abroad programs have changed dramatically since the disruption of international exchange during the Covid-19 pandemic. With many online events, abundant flow of information, and online communities to choose from, there is a need to plan and develop new programs that meet the needs of prospective students and universities. Osaka University has built an online international student recruitment system through the planning and implementation of online study abroad information events, virtual study abroad programs, and international student exchange activities, as well as through the establishment of a support system for international student applications and admissions and career guidance and job-hunting support. This paper describes the planning backdrop, actual practices, and future directions of the “Virtual university tours: a new tool to recruit international students with diverse linguistic and cultural backgrounds” hosted by Osaka University as a secretariat of the Japan Forum for Internationalization of Universities. Leveraging its accumulated experience, Osaka University held a virtual university tour to recruit international students aiming for the post-Covid era. The activities promote all-Japan recruitment of international students in the new normal and contribute to the construction of a cooperative framework. The purpose of this paper is to discuss the results of the implementation of this project, analyze its challenges, and look at the possibilities for further development of international exchange activities that strengthen lateral cooperation.教育実践レポートPractice Report

knowledge management based personalized service

论文介绍了知识管理的兴起和相关基本概念,应用于客户服务所带来的前景以及对个性化服务所提出的挑战。结合项目研究,论文基于对客户服务和个性化服务的理解,提出了一种基于知识管理的个性化服务机制及其实现方案

Compatibilization Mechanism of PC/UHMWPE/HDPE-g-GMA by Reactive Extrusion Process

通过对增容前后共混物的冲击断面形态、Molau实验现象、动态粘弹行为差异的研究和增容共混物抽提物的结构表征,探讨了共混体系的反应挤出增容机理.FT IR分析表明抽提残余物中含有 PC g HDPE接枝物,增容共混物的 Tg、Tmax向低温方向偏移3~4℃,证实了熔融共混过程中增容剂 HDPE g GMA的环氧基团与 PC的酚羟基发生“原位”化学反应,并生成PC g HDPE接枝物;该接枝物分布于两相界面,起到提高界面粘结力、促进 UHMWPE分散等作用,产生了良好的增容效果,属反应性增容作用机理.The difference between compatibilized and uncompatibilized blends on Molau test,fracture morphological structures undergone impact test and DMTA test was studied.Then,compatibilization mechanism of PC/UHMWPE/HDPE-g-GMA blends was discussed.FT-IR analysis showed that extractive of compatibilized blends contained the PC-g-HDPE graft copolymer and DMTA test indicated that T_g,T_(max) of PC for compatibilized blends decreased 3~4℃,which proved that there was “in site” chemical reaction between the epoxy groups of HDPE-g-GMA and the phenolic hydroxyl groups of PC in reactive extrusion process.PC-g-HDPE, which originated from “in site” chemical reaction,was mainly dispersed in interphase.It increased acting force of interphase,prevented congregation of dispersed phase,promoted dispersion of dispersed phase.HDPE-g-GMA improved compatibilization of PC/UHMWPE blend by reactive compatibilization mechanism

Studies on the Interaction between Graphene and p53-DNA by Molecular Dynamics Simulations and Spectroscopic Methods

Graphene and its derivatives have been widely used in the fields ranging from energy to biomedicine because of its peculiar physical and chemical properties. However,limited attention has been paid to potential hazards of graphene to organisms and environments. In this study,the interaction between graphene and the promoter region of p53 gene (p53-DNA) was investigated using molecular dynamics simulation (MD) technology and spectroscopic methods based on the combination of UV-vis absorption,DNA melting point test and fluorescent spectra,followed by the illustration of the interaction mechanism. MD results showed that some aromatic moieties of graphene could intercalate into the p53-DNA base pairs,which relied on pi-pi stacking interaction between aromatic moieties of graphene and p53-DNA base,and the other parts of graphene could further combine with p53-DNA by groove binding. Moreover,spectroscopic tests exhibited that graphene could increase the melting point (T_m) of p53-DNA and lead to static fluorescence quenching of EB-DNA system,suggesting that graphene was indeed able to bind with p53-DNA. Meanwhile,the ascent of absorbance of 260 nm was found in the p53-DNA as a result of the combination of graphene and p53-DNA,which meant graphene posed some effect on the double helix structure of p53-DNA. In conclusion,the mechanism of interaction between graphene and p53-DNA was investigated at molecular level in this study,which contributed to a further understanding of the toxicological effects of graphene

A Review of Pollution Status and Toxicological Researches of Typical Brominated Flame Retardants Tetrabromobisphenol A(TBBPA)and Decabromodiphenyl Ethane(DBDPE)

With hexabromocyclododecane(HBCDs)and poly brominated diphenyl ethers(PBDEs)listed as persistent organic pollutants(POPs),tetrabromobisphenol A(TBBPA)and decabromodiphenyl ethane(DBDPE)have become two of the most widely produced and used brominated flame retardants(BFRs).The underlying ecological risk of TBBPA and DBDPE have received increasing attentions since these two typical BFRs are being detected at high concentrations in environmental media.This paper summarized the pollution status of TBBPA and DBDPE and their toxicological effects.TBBPA and DBDPE have been detected in multiple environmental media,such as atmosphere,waters,soil,sediment and organisms.In addition,more severe pollution could be found in industrial areas.TBBPA and DBDPE were even found in human body and breast milk.Overall,TBBPA presented developmental toxicity,hepatorenal toxicity,endocrine disruption effect,reproductive toxicity,and neurotoxicity,while DBDPE showed developmental toxicity,hepatorenal toxicity,and endocrine disruption effect.According to the limited reports on DBDPE toxicity,we concluded that DBDPE was of relatively low toxicity.The aim of this review is to help evaluate the environmental risk,analyze the environmental capacity,and governmentally control the production of TBBPA and DBDPE

菲律宾蛤仔(Ruditapes philippinarum)金属硫蛋白基因克隆及Cd~(2+)胁迫下的表达分析

金属硫蛋白(Metallothionein,MT)是一类富含半胱氨酸的小分子蛋白质,参与机体重金属解毒和金属元素代谢等生理过程。本研究采用RACE技术,克隆获得了菲律宾蛤仔(Ruditapesphilippinarum)金属硫蛋白(RpMT)的全长cDNA序列。RpMT的cDNA全长为570bp,编码75个氨基酸,包含15个MT所特有的Cys-Xn-Cys结构。采用实时荧光定量PCR技术,分析了两种壳色菲律宾蛤仔(白蛤和斑马蛤)RpMT基因在Cd~(2+)暴露后的表达变化。结果发现:Cd~(2+)急性和亚慢性暴露均可导致两种壳色蛤仔消化腺和鳃组织RpMT基因表达量的显著上调;暴露后两种壳色蛤仔鳃组织RpMT基因表达量的增加幅度均高于消化腺组织,且以白蛤鳃组织基因表达水平的上调幅度较高。上述结果表明,RpMT可能在菲律宾蛤仔抵御Cd~(2+)胁迫过程中发挥了重要作用

CLONING AND EXPRESSION OF METALLOTHIONEIN GENE IN RUDITAPES PHILIPPINARUM EXPOSED TO CADMIUM

金属硫蛋白(Metallothionein,MT)是一类富含半胱氨酸的小分子蛋白质,参与机体重金属解毒和金属元素代谢等生理过程。本研究采用RACE技术,克隆获得了菲律宾蛤仔(Ruditapesphilippinarum)金属硫蛋白(RpMT)的全长cDNA序列。RpMT的cDNA全长为570bp,编码75个氨基酸,包含15个MT所特有的Cys-Xn-Cys结构。采用实时荧光定量PCR技术,分析了两种壳色菲律宾蛤仔(白蛤和斑马蛤)RpMT基因在Cd~(2+)暴露后的表达变化。结果发现:Cd~(2+)急性和亚慢性暴露均可导致两种壳色蛤仔消化腺和鳃组织RpMT基因表达量的显著上调;暴露后两种壳色蛤仔鳃组织RpMT基因表达量的增加幅度均高于消化腺组织,且以白蛤鳃组织基因表达水平的上调幅度较高。上述结果表明,RpMT可能在菲律宾蛤仔抵御Cd~(2+)胁迫过程中发挥了重要作用