Advanced prostate cancer with normal serum prostate-specific antigen values

臨床病期C及びDの新鮮前立腺癌131症例中, 治療前の血清PSA値が正常値を示した10例の組織型は一定ではなく, 予後はかならずしも不良ではなかった.前立腺組織のPSA免疫染色で5例が陽性を示しその組織分化度は高い傾向であった.3例が陰性を示し, その組織分化度は低い傾向にあり, 2例は評価不能であった.再燃症状をきたした3例は, 再燃時には血清PSA値の上昇を認めなかったAlthough prostate-specific antigen (PSA) is a valuable marker of prostate cancer, some untreated patients with advanced prostate cancer have normal PSA values. Over a period of 5 years, we reviewed pretreatment serum PSA levels in 131 patients with advanced prostate cancer (stages C and D). Ten patients (7.6%) had normal PSA values. The histological type of prostate cancer associated with normal PSA values was variable and the prognosis was not so poor. Immunostaining for PSA was performed on the resected prostate tissue of the 10 patients. PSA staining was positive in 5 cases, negative in 3 cases, and equivocal in the remaining 2 cases. In conclusion, PSA is not always useful, especially for following patients with normal PSA values

オオサカ コウシュウ エイセイ キョウカイ ヲ カタル

座談

Society and community engagement in Japanese universities : A government-funded university childcare support project

Until 2005, it was a common idea that education and research are universities’ only mission in Japan. However, in 2005, the Central Council of Education stated that the ‘university has education and research as its original mission. At the same time, the role expected of the university is also changing, and now the importance of the contribution to society/community of the university is being emphasized’. Therefore, with this reference to the indispensability of the university’s contribution to society and community, its involvement in such has increased in both quality and quantity during the past 15 years in Japan. On the other hand, the term social and community engagement (SCE) is used rather than contribution to society/community abroad. Kobe Tokiwa University’s four departments—medical technology, nursing, child education, and oral health—are able to alleviate many of the problems that accompany related issues. From 2017 through 2021, this university will be implementing childcare support with the collaboration of citizens, the municipal government, and the university and supported by the Ministry of Education, Culture, Sports, Science and Technology’s Private University Research Branding Project. As a result of considering SCE in universities in Japan based on the activities in this project, SCE is a relationship where local residents, local governments, and universities contribute to the growth of both. It was suggested that promotion of community-based research is one of the key points for SCE.| 2005年に公表された「我が国の高等教育の将来像(答申)」(中央教育審議会)において、「社会貢献の役割を、言わば大学の『第三の使命』としてとらえていくべき時代となっている」と示された。それ以来、わが国における大学の社会貢献は質・量ともに増加した。一方、国外ではソーシャル／コミュニティ・エンゲージメント(以下、SCE)という言葉が散見されるようになっている。本学は医療検査、看護、こども教育、口腔保健の4学科を有しており、開学以来、地域とのつながりを重視し、本学が位置する自治体とも地域連携協定を結んでおり、2017年には文部科学省の私立大学研究ブランディング事業に採択された。本事業における活動をもとにして、わが国の大学におけるSCEについて検討した結果、SCEは地域住民・自治体・大学が「双方の成長に貢献しあう関係」であり、そのためにはコミュニティ・ベースド・リサーチを推進していくことが1つの要であることが示唆された

大型ヘリカル装置のIC聾アンテナと加熱特性

Ion－cyclotron heating was applied to the Large Helical Device by using single, trap loop antennas located at the outward side of the toroid. Good experimental results were obtaine with adequate plasma　confining configurations and antenna conditionings．Loading resistance of the antenna was2－8Ohm and　this was a sufficiently large value. Various heating characteristics were investigated by changing the　heating modes, ion species and magneticfield configurations．The minoriy-ion heating mode resulted in the best heating performances，and the heatin gcharacteristics largely depended on the cyclotron resonance positions．There were some unique features due to the heliotron configuration．These results showed the　effectiveness of the ICRF heating in a helical device and the appropriateness of the ICRF antenna design　in the LHD