《中国古代买地券研究》评介

买地券是一种冥世契约,是传统民间葬仪所使用的重要文本,其内容大抵是记录亡人或其亲属自冥世买得墓地,立此契为证,为亡人息冥世之讼,为生人求现世福荫。今所见买地券,最早属于东汉时期,两千年来,沿用不绝,直至今日,部分地区仍延续此风俗。于史家而言,古代买地券既是珍贵的出土材料,可与"纸上之遗文互相释证";又是真正的民间文献,反映民间生活之实相,顺应社会史之洪流,得预契约史之浪潮。故而近代以来,瞩目者众多,或著录

Sodium/calcium exchanger inhibitor SN-6 rescued heart dysfunction and cell death in calcium paradox

目的评价钠-钙交换体选择性抑制剂Sn-6对钙矛盾处理造成离体灌注大鼠心脏功能障碍和心肌细胞死亡的影响。方法离体心脏先后经历3 MIn无钙液、30 MIn有钙液灌注即钙矛盾处理,实验同步监测左室功能,并检测复钙期冠脉流出液乳酸脱氢酶(ldH)含量与实验结束时存活心肌组织面积的大小。结果钙矛盾处理使得左室功能丧失,表现为左室舒张末压(lVEdP)显著抬高,左心室发展压(lVdP)、心室压力变化最大速率(±dP/dT)为0;心脏几乎不存在活性组织;于无钙液灌注前2 MIn、无钙液灌注期和复钙后前5 MIn给予10μMOl/l Sn-6处理后,lVEdP显著降低,lVdP和±dP/dT明显恢复,心肌损伤面积缩小,ldH释放减少;Sn-6处理的对照心脏于灌流结束时左室功能没有显著改变。结论 Sn-6具有减轻钙矛盾处理造成的心功能损害,增加细胞存活的作用,提示钠-钙交换体是钙矛盾损伤的关键分子。Objective The present study was to observe the effect of sodium /calcium exchanger inhibitor SN-6 on heart dysfunction and cell death induced by calcium paradox.Methods Calcium paradox in isolated heart was elicited by 3-min calcium depletion followed by 30-min calcium repletion in the absence or presence of 10 μmol/L SN-6,an inhibitor of sodium/calcium exchanger.Cardiac function was monitored,and lactate dehydrogenase(LDH) release during calcium repletion and infarct size was measured.Results Upon calcium repletion,the heart deteriorated,exhibiting a marked depression in cardiac function,an enlarged infarct size and an increase in LDH release.These changes were significantly attenuated by SN-6.SN-6 had no effect on cardiac performance at the end of perfusion under control conditions.Conclusion The results demonstrate that SN-6 rescues heart dysfunction and cell death in calcium paradox.It also indicates that sodium/calcium exchanger is a key molecule in the injury.国家自然科学基金(30971196

A Meibomian Gland Massage Mechanism for Upper and Lower Eyelids Based on Anti-phase Rolling and Enveloping Movement

在睑板腺功能障碍的治疗过程中,睑板腺按摩是一种有效的辅助治疗手段。该文针对传统的机械辅助按摩结构中的缺陷进行了改进,提出了一种基于反相按摩辊滚压和包络原理的按摩机构,以提高阻塞物排出顺畅度和提高按摩区域覆盖率,最终达到提高辅助治疗效果的目的。同时,针对机构中电机受尺寸影响较大的情况,对运转过程中输入动力与输出载荷和损耗进行了评估计算,初步验证了所设计机构的可行性。During the course of meibomian gland dysfunction(MGD) treatment, meibomian gland massage is an effective auxiliary method.Based on an extrusion method using anti-phase massage rollers and a theory on envelope plane, a massage mechanism was proposed in this paper for the defect of the traditional mechanical assist massage structure to discharge obstruction of Meibomian gland more smoothly and to enlarge massage coverage.Meanwhile, for the case that the power of motor was significantly limited by size, an evaluation, about the input, output and loss, was carried out to initially verify the feasibility of the designed mechanism

Research of Flexible Gasbag Hot Compress Therapy of Meibomian Gland Massage Using Carbon Fiber

睑板腺功能障碍是引发干眼症的主要原因之一。睑板腺按摩配合热敷是一种治疗睑板腺功能障碍的有效辅助手段。该文针对自主设计的辊式睑板腺按摩仪,对其柔性气囊的热敷方式进行设计。采用碳纤维作为电发热丝,构成与柔性基材集成的电路,并配合控制电路,实现了对气囊的加热和温度控制。同时,研究了气囊与碳纤维的集成工艺,利用热压技术实现了碳纤维和柔性TPu薄膜的紧密结合,而不会影响按摩仪的按摩效果。该方法还可应用到其他以柔性材料为基材实现热敷的医疗器械中。Meibomian gland dysfunction(MGD) is one of the main reasons for dry eye and Meibomian gland massage with hot compress therapy is an effective adjutant therapy for MGD.Based on the self-designed meibomian gland massager, a method of heating is designed with flexible gasbag in this paper.With control circuit and flexible circuit made of carbon fiber, as electric heating wire, it's able to heat the gasbag and control the temperature.An integrated technology for gasbag and carbon fiber which using hot-pressing to make TPU and carbon fibers fit closely together, will not have influence on the massage.According to this, this technology is applicable for other medical devices with flexible material and hot compress therapy

The Research on Flower Colors and Anthocyanins in Ornamental Sunflower (Helianthus annuus L.)

观赏向日葵作为一种新型花卉，具有巨大的市场开发潜力。而花色作为向日葵的重要观赏性状之一，对其的研究却比较少。本文从向日葵花色多样性、花色遗传规律、花色与虫媒传粉的关系及其对向日葵花色遗传的影响做了分析和讨论，利用英国皇家园艺学会比色卡和分光色差仪对向日葵的花色做了归类总结，并且利用高效液相色谱法对向日葵的花青苷成分做了分析研究。 本研究结果表明，彩色向日葵色系可以分为两大类，即黄色系和红色系，其中红色系向日葵的花色变异较小；而黄色系向日葵的花色变异较大，可以再细分为橙黄色和柠檬黄色两个亚类。利用高效液相色谱法测定了39份向日葵舌状花瓣中的花青苷大概有9种(A、B、C、D、E、F、G、H、I)，这9种花青苷并不是在所有39份样品中都出现，且红色系向日葵中花青苷的种类较多。花青苷G在红色系和黄色系向日葵中均被检出。对红色向日葵花瓣的花青苷提取液进行多级质谱分析发现，花青苷元类型主要是矢车菊苷元，其糖苷类型主要是和葡萄糖、鼠李糖和/或阿拉伯糖结合；而在纯黄色的向日葵中通过多级质谱分析未检测到这些花青苷，说明矢车菊类花青苷是红色向日葵舌状花红色形成的化学基础