14,737 research outputs found
The Macroregional Control during the Medieval China — A Case Study on Long You Dao in Tang Dynasty
区域考察是研究中国历史的重要视角,亦是本文的出发点。但在区域的分划上,本文并未选择自然地理区划、市场体系等作为划分依据,而是借助王朝国家所建立的大区控制体系以作为分区的依据。在此基础之上,再去探讨王朝国家试图控制大区的过程、方式及其意义,亦即将区域置于王朝国家对于地方控制的政治进程中进行讨论。本文即是以唐代的“陇右道”为切入点,通过大区的划分,控制与意义三部分进行考察,得出以下四点认识: (1)贞观十道划分时,将“陇右道”所辖的河、陇二十一州冠以“陇右”之名,是对前代“陇右”观念演变结果的继承。“陇右”一名初见于两汉之际,作为一种宽泛的地理观念,常与“河西”对举,大体指陇山以西,黄河以东地区...Regional research is an important perspective for studying Chinese history,and it is also the starting point of this dissertation. However, in the aspect of region division, the author does not choose to divide a region with certain standards, such as geographical features and marketing systems, but according to the macroregional control system that a dynastic state establishes. And on this basis,...学位:历史学博士院系专业:人文学院_历史地理学学号:1032012015370
Design and Implementation of University Student Information Management System
学生信息管理系统是高校教学管理中一个重要的组成部份,是高校一项重要数据资源,既给学校的决策者和管理提供辅助决策,也能为直接管理学生的管理部门和人员提供方便。 由于信息里大、数据多、需更新及时,传统的人工化和纸制化管理方式对学生信息维护、更新、修改和查询,是一件繁琐的事情,且容易出错,已不能满足现代化管理的需要。所以,开发一套学生信息管理系统应运而生。 系统采用了C/S架构,采用易语言进行开发。学生信息管理系统具有系统登录、系统管理、学生信息管理、学生评测管理、学生信息查询和常用工具管理等功能。设计完成后的系统为各种管理人员提供了不同的功能。 论文共分为七部分,首先是绪论,介绍课题研究背景...Student information management system is an important component part of teaching managementand is an important data resource of colleges, which not only provides decision support for policy makers and college management, but also facilitates management departments and staff that manage student information. Because the huge amount of information and abundant data need to be updated in a timely ...学位:工程硕士院系专业:软件学院_软件工程学号:X201323004
Design and Implementation of a Hypermarkets Company Business Management Information System
随着信息技术的飞速发展,以及现代社会中管理信息理念的普及,管理信息系统广泛应用到现实生活的各个领域。与此同时,随着国内经济的快速发展,中小型的商品零售企业,例如各种连锁超市、百货商场、购物广场越来越多,这些企业经营的商品种类繁多、供应商数量庞大、分店分布散乱难以管理,为了解决这些问题,企业必须利用先进的管理信息系统来提高管理水平。随着我国社会主义市场经济体制的巩固和发展,很多企业规模的不断扩大,连锁门店的扩张是零售行业发展的主要方式。但是随着连锁门店的不断增加,企业对旗下门店、销售、财务结算、供应商以及采购招商的管理越来越复杂,传统的手工管理方式已经不能够满足零售企业发展的需要,零售企业必须加...With the rapid development of information technology, and the population of information management concept in modern society, management information systems are widely applied to various areas of real life. At the same time, with the rapid development of the domestic economy, more and more small and medium sized retail businesses is coming out, such as various supermarket, department stores, shopp...学位:工程硕士院系专业:软件学院_工程硕士(软件工程)学号:X201323238
The effect and mechanism of IL-1 R II / IL-1 RAcp in Autoimmune Myocarditis
【目的】白介素-1(IL-1)是一种T淋巴细胞激活因子,大量研究报道,在心肌炎急性期表达量明显升高。白介素1受体II型(IL-1RII)可以招募白介素1受体辅助蛋白(IL-1RAcp),从而拮抗IL-1β的作用。本课题目的为评估IL-1RII和IL-1RAcp的重组质粒对大鼠自身免疫性心肌炎(EAM)的作用,并进一步探讨其机制,为心肌炎的临床治疗提供理论基础。 【方法】首先在临床实验中,我们选取厦门市心血管病医院诊断明确的心肌炎住院患者28例,应用bio-plex蛋白芯片技术检测其血浆内15种炎性因子的表达;在体内实验,第0天免疫Lewis大鼠建立EAM模型,并在第10天导入重组质粒pCAG...【Purpose】Interleukin-1 is an activator of T lymphocyte cells, and highly express in acute myocarditis according to massive reports. IL-1RII can completely inhibit the combination of IL-1β by recruiting IL-1RAcp. This experiment aims to estimate the effect of IL-1RII/IL-1RAcp recombinant plasmids in treatment with experimental autoimmune myocarditis (EAM), and elucidate the mechanism in treatment, ...学位:医学硕士院系专业:医学院_内科学学号:2452013115347
Design and Implementation of Students Financial Assistance Management System for a University Base on .NET
目前我国高等院校的家庭经济困难学生资助问题已成为学院关注的焦点问题,而家庭经济困难学生资助工作已经成为学校学生管理工作中的一项重要内容。然而目前大部分高等院校在学生资助工作时仍然是手工或半自动化管理方式,工作效率和质量都很低。因此决定利用网络技术和信息化技术对普通高校的学生资助管理进行了优化设计,对学生资助管理和流程审批的业务需求进行深入分析,开发一个适合于普通高校的学生资助管理系统。 本文根据目前高等院校的学生资助管理的实际工作需要,分析了普通高校的学生资助管理系统的整体业务需求,确定系统的总体流程,然后使用UML工具进行系统的业务需求详细分析,描述了系统的功能性需求和非功能性需求;然后探...The problem of financially strapped students became the central issue of Colleges and universities. The subsidizing of financially strapped students had been the macro content of high school students management. The management style of students financial assistance of Colleges and universities is manual stage and office tools, which causes low efficiency and quality, Therefore, deciding to use ne...学位:工程硕士院系专业:软件学院_工程硕士(软件工程)学号:X201323006
Design and Implementation of Personnel Information Management System for an Enterprise
当前,市商业银行作为某市重点建设的银行企业之一,在市场竞争中暴露出统一管理难度大、考核制度不够完善、招聘和培训效率低下等问题,为此,本行需要开发了一套人力资源管理信息系统。 为了从根本上解决银行存在的管理问题,本文提出了一套人力资源信息管理系统。本系统采用了J2EE技术架构中的SSH框架和JSP动态网页技术,结合软件工程思想,通过面向对象的编程方式,以SQLServer2008作为后台数据库,MyEclipse为开发平台,实现了组织机构管理、人员信息管理、人员变动管理、人员合同管理、员工培训管理等功能模块。通过对单位、部门、岗位、编制信息维护,构建了完整的组织机构网络;通过对人员信息的管理,...As one of the key constructed bank in the city, the commercial bank exposes lots of problems, such as the difficulty of management in market competition, the imperfection of the appraisal system, recruitment and training problem are such low efficiency, therefore, the bank need to develop a set of human resource management information system, to improve the management of human resources. In order...学位:工程硕士院系专业:软件学院_工程硕士(软件工程)学号:X201323148
Analysis on amide synthase and methyltransferase in biosynthesis of streptovaricin from the strain NRRL 2494
曲张链菌素(streptovaricin)是由壮观链霉菌(Streptomycesspectabilis)NRRL2494产生的安莎类抗生素,与抗结核药物利福霉素具有相似的化学结构骨架,具有抗菌及免疫抑制等多种生物活性。本论文在对NRRL2494菌株基因组测序的基础上,获得曲张链菌素生物合成基因簇,并通过构建稳定的遗传操作体系,研究其生物合成途径中重要基因的功能,为利用组合生物学手段获得成药性好的曲张链菌素类化合物奠定基础。 本论文首次分析了NRRL2494菌株的基因组全长17.5MB序列,并通过生物信息学分析得出了曲张链菌素生物合成基因簇序列含有37个开放阅读框,总长度约为91.5kb。结...Streptovaricin, produced by Streptomyces spectabilis NRRL 2494, is a kind of ansamycins with similar chemical structure to the well known antituberculous drug rifamycin. Streptovaricin has significant biological activity. This paper aims to obtain streptovaricin biosynthetic gene clusters on the basis of the strain NRRL 2494 whole-genome sequencing and then elucidate the functions of related impor...学位:理学硕士院系专业:生命科学学院_微生物学学号:2162012115238
Laboratory experiments on bacterial weathering of granite and its constituent minerals
Thesis (Ph. D. in Science)--University of Tsukuba, (A), no. 4973, 2009.3.25Includes bibliographical references (leaves 52-63
Silencing of PKM2 promotes Fas-Dependent Apoptosis via P53 -Mediated in Gastric cancer Cells
背景和目的:PKM2作为丙酮酸激酶(pyruvatekinaseisoenzyme,PK)家族成员,在肿瘤中呈现高表达,并且在肿瘤能量代谢过程中起到关键作用。近期研究发现,PKM2还具备转录因子活性,参与调控细胞增殖与迁移侵袭,在恶性肿瘤的发生发展中发挥重要作用。我们研究发现,胃癌细胞株BGC823及AGS中基因沉默PKM2后,促进了顺铂诱导的细胞凋亡,由此表明PKM2可以减低胃癌细胞对化疗药物的敏感性,但具体机制有待探索,我们的研究旨在明确基因沉默PKM2在胃癌细胞凋亡及耐药方面的作用及相关分子信号通路。 方法:首先,运用短发夹RNA(shRNA)稳定转染胃癌细胞株BGC823和AGS,抑...Background and Aims: The M2 splice isoform of pyruvate kinase (PKM2) as a member of pyruvate kinase isoenzyme family , highly expressed in tumor cells, and plays an important role in the process of tumor metabolism. The latest study finds that PKM2 has an activity of transcription factor , participate in regulation of cell proliferation and migration, and plays an important role in the emergence ...学位:医学硕士院系专业:医学院_内科学学号:2452012115313
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