The Interpreter's Role as a Mediator of Face-Work in Government Press Conferences in Diplomatic Settings in China

伴随着口译研究范式的多样化发展，基于社会学理论的研究也逐渐屡见不鲜。口译不再被看作是发生在社会“真空”环境下的单纯的语言类活动，而学者们更多地将其作为一种社会情境下的交际活动来研究。与此同时，学界对译员角色的看法也发生了本质性改变。译员不再被看做是透明的“机器”或“管道”，转而变成了显身并具有主体意识的交际参与者。随着学者们对译员角色的日益关注，它已然成为了口译研究中的重要课题。 本文的研究对象为外交场合下译员的“面子协调者”角色。“面子协调工作”这一概念最初由美国社会学家尔文•戈夫曼提出，它指的是个人为了维护自身面子而采取的一系列行动（1972:12）。已有的一些研究证明译员会...With the broadening scope of paradigms of interpreting studies, scholars are increasingly focusing on the interdisciplinary aspect of interpreting researches and there are more and more studies in light of sociological theories. Researchers no longer regard interpreting as a speech event happening in “vacuum” regardless of social factors, but as authentic social interactions. Accordingly, breakthr...学位：翻译硕士院系专业：外文学院_英语语言文学学号：1202013115277

Discussion on the Participation of Infantile Massage in Community Health Care

小儿推拿具有取穴少、经济安全、操作简单、家长易学等优点,适合在社区中推广。本文就其参与社区卫生服务的方式、内容、优势、问题和解决方法等方面,对实现小儿推拿“家庭化“进行论述,认为小儿推拿参与社区卫生服务最理想的方式是实现其“家庭化“,且“家庭化“的建立将是医疗技术进入社区的重要措施,是家庭卫生服务中最具特色的形式之一。Infantile massage has many advantages,for example,less acupoint selection,economic,safe,simple operation and easy to learn.It's suitable for promoting in the community.From aspects of methods,details,advantages,problems and solutions of infantile massage participating in community health service,the paper discussed infantile massage "family oriented"and thought that achieving its "family oriented"was the best way of infantile massage participating in community health service.The building of its"family oriented"was the key of medical technology entering into the community,and was one of the most unique forms of the family health service

Design of Auxiliary Converter for HXD1C Electric Locomotive

This paper presents the main circuit, technical parameters and general structure of the auxiliary converter for HXD1C six-axle electric locomotive with 7 200 kW. The control unit and technical characteristic of this auxiliary converter are mainly analyzed. The actual operation shows that the performance of this auxiliary converter is stable and it can meet the requirements of HXD1C electric locomotive

科学研究（科研管理）信息知识化服务研究

通过 e-science 环境下科研信息需求的变化与挑战分析，结合中科院文献情报中心学科信息知识化服务实践，尝试提出嵌入科研、科技管理全程的数字化知识化的信息服务及其环境建设思路与方法

Interplay between transforming growth factor-β and Nur77 in dual regulations of inhibitor of differentiation 1 for colonic tumorigenesis

细胞核受体Nur77和转化生长因子β（TGFβ）同结肠癌的发生发展密切相关。尽管目前学界对它们在结肠癌中的功能和作用机制有一定的认知，但仍有诸多问题有待解决。厦大药学院周虎教授团队发现，在结肠癌发生发展过程中，Nur77和TGFβ信号之间存在双重交互作用，这种交互作用产生了对分化抑制因子ID1的双层、双向的调节作用，进而调节结肠癌的发生发展。 此研究工作依托福建省药物新靶点研究重点实验室和厦门大学高通量药物筛选平台，由厦门大学药学院和香港中文大学生物医学学院共同完成，其中厦门大学为第一完成单位。周虎教授为文章的通讯作者，药学院博士研究生牛播宁为第一作者，博士研究生刘洁是第二作者。同时香港中文大学生物医学研究院的蒋晓华教授和林佳城博士也为研究做成了重要贡献。【Abstract】The paradoxical roles of transforming growth factor-β (TGFβ) signaling and nuclear receptor Nur77 in colon cancer development are known but the underlying mechanisms remain obscure. Inhibitor of differentiation 1 (ID1) is a target gene of TGFβ and a key promoter for colon cancer progression. Here, we show that Nur77 enhances TGFβ/Smad3-induced ID1 mRNA expression through hindering Smurf2-mediated Smad3 mono-ubiquitylation, resulting in ID1 upregulation. In the absence of TGFβ, however, Nur77 destabilizes ID1 protein by promoting Smurf2-mediated ID1 poly-ubiquitylation, resulting in ID1 downregulation. Interestingly, TGFβ stabilizes ID1 protein by switching Nur77 interaction partners to inhibit ID1 ubiquitylation. This also endows TGFβ with an active pro-tumorigenic action in Smad4- deficient colon cancers. Thus, TGFβ converts Nur77’s role from destabilizing ID1 protein and cancer inhibition to inducing ID1 mRNA expression and cancer promotion, which is highly relevant to colon cancer stemness, metastasis and oxaliplatin resistance. Our data therefore define the integrated duality of Nur77 and TGFβ signaling in regulating ID1 expression and provide mechanistic insights into the paradoxical roles of TGFβ and Nur77 in colon cancer progression.We thank Prof. Dieter A. Wolf (Xiamen University) for the assistance of manuscript writing, Prof. Ye-guang Chen (Tsinghua University) for kindly providing the CAGA-luciferase reporter, ca-TβRI, and original Smads plasmids, Prof. Yunbin Ye (Fujian Cancer Hospital) for kindly providing the GFP-ID1 expression plasmid, and Prof. Hongrui Wang (Xiamen University) for kindly providing the Smurf2C716A expression plasmid, and tumor pathologist Huamei Tang (Xiang’an Hospital of Xiamen University) for analyzing tumor tissues. This work was supported by grants from the National Natural Science Foundation of China (32070779, 31770811, 31471318, 31271453, 91129302, and 81301888), the Regional Demonstration of Marine Economy Innovative Development Project (16PYY007SF17), and the Fujian Provincial Science & Technology Department (2017YZ0002-1). 该项目研究得到了周虎教授主持的国家自然科学基金面上项目（32070779）等基金的支持

我国圈养和野生东北虎种群线粒体基因组遗传多样性的比较研究

东北虎（Panthera tigris altaica）是体型最大的猫科（Felidae）动物之一，是极具代表性的珍稀野生动物。现有研究表明，我国野生东北虎种群遗传多样性较低、近交水平较高。尽管目前我国野生东北虎的数量在逐步增长，但通过人工干预来提高野生东北虎的遗传多样性会更利于其数量的恢复，通过野化放归进行遗传拯救是一种关键策略，但实施遗传拯救之前，必须确定圈养个体与现存野生个体间的遗传关系。采用粪便DNA的高通量测序数据组装了51只横道河子圈养东北虎和13只完达山、老爷岭等地的野生东北虎的线粒体基因组，分析两者之间的关系，评估线粒体基因组的遗传多样性。结果表明：圈养东北虎的遗传多样性高于野生种群，所有遗传变异均为无害。部分圈养个体与野生种群同属一个进化支，且具有野生种群所不包含的遗传变异，可用于实施遗传拯救。此外，圈养种群存在显著的遗传分化，一个与当前野生种群关系很远的分支可能代表未知的地理种群，因此，建议对该远缘分支开展野外来源的追溯，确定其谱系地理学地位和保护价值，使其成为恢复野外历史遗传多样性的后备资源