3 research outputs found
ΠΠΠ€ΠΠΠΠΠΠΠΠ«Π Π‘ΠΠΠΠ‘Π’ΠΠ ΠΠΠΠ’ΠΠ₯ΠΠΠΠΠΠΠ§ΠΠ‘ΠΠΠΠ ΠΠΠΠΠΠΠ ΠΠΠΠ’ΠΠ€ΠΠ Π ΠΠΠ Π§ΠΠΠΠΠΠΠ
Background:Β Recent research shows that the growth and development of the gastrointestinalΒ tract of children fed by breast milk is more intense than that of the formula fed, since the human lactoferrin contained in the breast milk is a factor that stimulates cell growth. Therefore, the possibility of using exogenous lactoferrin will be of great importance in the nutrition of infants.Objektive: To study the bifidogenic properties of the biotechnological analogue of human lactoferrin. Methods: Kinetics of growth and CFU titer of bifidobacterial culture in the presence of a biotechnological analogue of human lactoferrin (0,05β5 mg /ml) was determined.Results: It has been shown that different concentrations of the protein can have both a stimulating (for B. bifidum and B. infantis) and inhibitory (for B. longum) effect on the growth of bifidobacteria, which is due to the affinity of lactoferrin binding to them. It seems important to further study the stimulating effect of this protein on the growth of lactobacilli in the intestine of the child.Conclusion:Β Due to bifidogenic and high bactericidal action, lactoferrin can be effective in feeding newborns.ΠΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠ΅.Β Β ΠΠΎΠ²Π΅ΠΉΡΠΈΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΒ ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡ,Β ΡΡΠΎΒ ΡΠΎΡΡΒ ΠΈ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅Β ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎ-ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎΒ ΡΡΠ°ΠΊΡΠ°Β Π΄Π΅ΡΠ΅ΠΉ, Π²ΡΠΊΠ°ΡΠΌΠ»ΠΈΠ²Π°Π΅ΠΌΡΡ
Β ΠΌΠ°ΡΠ΅ΡΠΈΠ½ΡΠΊΠΈΠΌ ΠΌΠΎΠ»ΠΎΠΊΠΎΠΌ,Β ΠΏΡΠΎΠΈΡΡ
ΠΎΠ΄ΠΈΡΒ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½Π΅Π΅,Β ΡΠ΅ΠΌ Ρ Π²ΡΠΊΠ°ΡΠΌΠ»ΠΈΠ²Π°Π΅ΠΌΡΡ
Β ΠΌΠΎΠ»ΠΎΡΠ½ΡΠΌΠΈ ΡΠΌΠ΅ΡΡΠΌΠΈ, ΠΏΠΎΡΠΊΠΎΠ»ΡΠΊΡ ΡΠΎΠ΄Π΅ΡΠΆΠ°ΡΠΈΠΉΡΡ Π² Π½Π΅ΠΌ Π»Π°ΠΊΡΠΎΡΠ΅ΡΡΠΈΠ½ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ°ΠΊΡΠΎΡΠΎΠΌ, ΡΡΠΈΠΌΡΠ»ΠΈΡΡΡΡΠΈΠΌ ΠΊΠ»Π΅ΡΠΎΡΠ½ΡΠΉ ΡΠΎΡΡ. ΠΠΌΠ΅Π½Π½ΠΎ ΠΏΠΎΡΡΠΎΠΌΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡΒ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΡΠΊΠ·ΠΎΠ³Π΅Π½Π½ΠΎΠ³ΠΎ Π»Π°ΠΊΡΠΎΡΠ΅ΡΡΠΈΠ½Π°Β Π±ΡΠ΄Π΅Ρ ΠΈΠΌΠ΅ΡΡ Π±ΠΎΠ»ΡΡΡΡ Π·Π½Π°ΡΠΈΠΌΠΎΡΡΡ Π² ΠΏΠΈΡΠ°Π½ΠΈΠΈ Π³ΡΡΠ΄Π½ΡΡ
Π΄Π΅ΡΠ΅ΠΉ.Π¦Π΅Π»ΡΒ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ β ΠΈΠ·ΡΡΠΈΡΡ Π±ΠΈΡΠΈΠ΄ΠΎΠ³Π΅Π½Π½ΡΠ΅Β ΡΠ²ΠΎΠΉΡΡΠ²Π° Π±ΠΈΠΎΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΎΠ³Π°Β Π»Π°ΠΊΡΠΎΡΠ΅ΡΡΠΈΠ½Π° ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°.ΠΠ΅ΡΠΎΠ΄Ρ. ΠΠΏΡΠ΅Π΄Π΅Π»ΡΠ»Π°ΡΡ ΠΊΠΈΠ½Π΅ΡΠΈΠΊΠ° ΡΠΎΡΡΠ° ΠΈ ΠΠΠ-ΡΠΈΡΡ ΠΊΡΠ»ΡΡΠΈΠ²ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π±ΠΈΡΠΈΠ΄ΠΎΠ±Π°ΠΊΡΠ΅ΡΠΈΠΉ Π² ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠΈ Π±ΠΈΠΎΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎΒ Π°Π½Π°Π»ΠΎΠ³Π° Π»Π°ΠΊΡΠΎΡΠ΅ΡΡΠΈΠ½Π° ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ ΡΠ°Π·Π»ΠΈΡΠ½ΡΠ΅ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ Π΄Π°Π½Π½ΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ° (0,05β5 ΠΌΠ³/ΠΌΠ») ΠΌΠΎΠ³ΡΡ ΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡ ΠΊΠ°ΠΊ ΡΡΠΈΠΌΡΠ»ΠΈΡΡΡΡΠ΅Π΅ (Π΄Π»Ρ Bifidobacterium bifidum ΠΈ Bifidobacterium infantis), ΡΠ°ΠΊ ΠΈ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΡΡΡΠ΅Π΅ (Π΄Π»Ρ Bifidobacterium longum) Π΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ Π² ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΈ ΡΠΎΡΡΠ° Π±ΠΈΡΠΈΠ΄ΠΎΠ±Π°ΠΊΡΠ΅ΡΠΈΠΉ,Β ΡΡΠΎ ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½ΠΎ Π°ΡΡΠΈΠ½Π½ΠΎΡΡΡΡΒ ΡΠ²ΡΠ·ΡΠ²Π°Π½ΠΈΡ Ρ Π½ΠΈΠΌΠΈ Π»Π°ΠΊΡΠΎΡΠ΅ΡΡΠΈΠ½Π°. ΠΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ΅ΡΡΡΒ Π²Π°ΠΆΠ½ΡΠΌ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠ΅Π΅ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΡΡΠΈΠΌΡΠ»ΠΈΡΡΡΡΠ΅Π³ΠΎ ΡΡΡΠ΅ΠΊΡΠ°Β ΡΡΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ° Π½Π° ΡΠΎΡΡ Π»Π°ΠΊΡΠΎΠ±Π°ΡΠΈΠ»Π» Π² ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ΅ ΡΠ΅Π±Π΅Π½ΠΊΠ°.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ»Π°Π³ΠΎΠ΄Π°ΡΡ Β Π±ΠΈΡΠΈΠ΄ΠΎΠ³Π΅Π½Π½ΠΎΠΌΡ ΠΈ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΠΌΡ Π±Π°ΠΊΡΠ΅ΡΠΈΡΠΈΠ΄Π½ΠΎΠΌΡ Π΄Π΅ΠΉΡΡΠ²ΠΈΡ Π»Π°ΠΊΡΠΎΡΠ΅ΡΡΠΈΠ½ ΠΌΠΎΠΆΠ΅Ρ Π±ΡΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ Π² Π»Π΅ΡΠ΅Π±Π½ΠΎΠΌ ΠΏΠΈΡΠ°Π½ΠΈΠΈ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΡΡ
BIFIDOGENIC PROPERTIES OF A BIOTECHNOLOGICAL ANALOGUE OF HUMAN LACTOFERRIN
Background:Β Recent research shows that the growth and development of the gastrointestinalΒ tract of children fed by breast milk is more intense than that of the formula fed, since the human lactoferrin contained in the breast milk is a factor that stimulates cell growth. Therefore, the possibility of using exogenous lactoferrin will be of great importance in the nutrition of infants.Objektive: To study the bifidogenic properties of the biotechnological analogue of human lactoferrin. Methods: Kinetics of growth and CFU titer of bifidobacterial culture in the presence of a biotechnological analogue of human lactoferrin (0,05β5 mg /ml) was determined.Results: It has been shown that different concentrations of the protein can have both a stimulating (for B. bifidum and B. infantis) and inhibitory (for B. longum) effect on the growth of bifidobacteria, which is due to the affinity of lactoferrin binding to them. It seems important to further study the stimulating effect of this protein on the growth of lactobacilli in the intestine of the child.Conclusion:Β Due to bifidogenic and high bactericidal action, lactoferrin can be effective in feeding newborns
EFFICIENCY OF USING THE ADAPTED GOATβS MILK FORMULA IN THE DIET OF HEALTHY YOUNG INFANTS: A MULTICENTER PROSPECTIVE COMPARATIVE STUDY
Background. There is no doubt that it is necessary to study the efficiency of milk formulas that are introduced into the Russian market of baby food. This applies to both new products and known brands of formulas whose composition is subject to change.Objective. Our aim was to assess the clinical efficacy of the adapted goat's milk formula in the diet of young infants.Methods. We conducted a prospective comparative study with healthy full-termΒ children aged 0β5 months being on a formula (main group) or breast feeding (comparison group). The tolerability of the adapted goat's milk formula, the dynamics of anthropometric indicators, changes in body composition as well as microscopic characteristicsΒ of stool and general clinical and biochemical parametersΒ of peripheral blood were assessed after 1 month.Results. Good tolerability of the goat's milk formula was noted in 184 (96.8%) of 190 children in the main group. In the course of taking the product, the proportion of children with functional disorders of the gastrointestinal tract decreased significantly from 57 (30%) to 27 (14%) (p < 0.001). Physical development,Β complete blood count results, the levels of ferritin, prealbumin and 25(OH)D in children of the main group and the comparison group (n = 71) were comparable and were within the mean age parameters. Qualitative analysis of the level of specific IgE to goat's milk proteins did not reveal any sensibilization in any of the children receiving the milk formula, either at the beginning of the study or after 1 month of taking the product.Conclusion. The studied adapted goat's milk formula can be used in nutrition of young infants in cases of lack or absence of mother's milk