Proposal of the manufacturing process of construction of a dwelling house

Import 29/09/2010Náplní této práce bylo řešit projekt obytného domu v kvalitě požadované pro stavební povolení. Práce se skládá z částí technologické a pozemní stavby. V části pozemní stavby je řešena technická zpráva a výkresová část s vybranými detaily. V technologické části je řešen rozpočet stavby s harmonogramem výstavby a technologický postup dílčí etapy, zaměřený na montáž krovu. Stavba je podsklepená se třemi nadzemními podlažími a zastřešená krove. Stavba je založena na železobetonových pasech, vyzděná z cihel typu POROTHERM. Projekt stavby je zasazen do zastavěného území v Ostravě – Porubě na ulici Polská.The aim of this work is an appartment house project solution on the level required for the building permit. The work consists of two parts – a technological part and a structural engineering. The second mentioned part – the structural engineering – solves the problem of a technical report and also specific drawings with some detailed parts. The technological part deals with a building budget along with a building harmonogram and a technology of the particular building phases, focused on the roof truss assemblage. The building includes a basement, three living floors and a roofeed truss. The building is founded on the steel concrete stripfoundation and bricked up as a Porotherm system. The building project is set to a developed area in the city of Ostrava, district Poruba, Polska Street.Prezenční225 - Katedra pozemního stavitelstvívelmi dobř

Administrative Building

Import 27/01/2012Náplní této práce je řešení projektu pro realizaci stavby Administrativní budovy v požadované kvalitě. členění práce je provedeno do šesti částí. V první části je řešena výkresová dokumentace stavby v rozsahu dle zadání spolu s projektovou dokumentací stavby. V druhé části se provádí porovnání variantního řešení výkopových prací (zajištění stěny pomocí svahování, pažení) a jejich porovnání z hlediska finanční náročnosti. V třetí části je řešen technologický postup s návrhem pracovní sestavy pro obě varianty. Ve čtvrté části je řešen rozpočet stavby, v páté části je řešen harmonogram výstavby a v poslední šesté části jsou řešeny Zásady organizace výstavby. Objekt je řešen jako monolitický železobetonový sloupový skelet s výplňovým zdivem typu Porotherm a zastřešen pomocí ploché střechy. Objekt má jedno podzemní podlaží, ve kterém je fitness centrum a čtyři nadzemní, ve kterých jsou kancelářské prostory.The scope of this work is the project for the Construction Office buildings on the level required quality. Breakdown of work is done in six parts. The first part dealt with construction drawings to the extent to specification together with the project documentation of the building. In the second part of the comparison is made variant solution excavation work (securing walls with sloping, sheeting) and their comparison in terms of financial cost. In the third part is solved technological process proposed by the Task reports for both variants. In the fourth part is solved by the construction budget, in the fifth part is solved by the construction schedule and the last sixth part are dealt with principles of construction organizations. The building is designed as a monolithic reinforced concrete column frame with masonry infill type Porotherm and roofed a flat roof. The building has a basement, which is a fitness center and four above ground, in which office space.Prezenční225 - Katedra pozemního stavitelstvívelmi dobř

Two phenotypes of chronic recurrent multifocal osteomyelitis with different patterns of bone involvement

Abstract Introduction Chronic Recurrent Multifocal Osteomyelitis (CRMO) is an autoinflammatory bone disorder with predominantly paediatric onset. Children present with multifocal osteolytic lesions accompanied by bone pain and soft tissue swelling. Patients often exhibit extraosseous co-morbidities such as psoriasis, inflammatory bowel disease, and arthritis. Objectives Comparison of children with two different phenotypes of CRMO defined by presence or absence of extraosseous co-morbidities. Methods Children diagnosed with CRMO at the Motol University Hospital between 2010 and 2020 were retrospectively reviewed, and according to the absence or presence of extraosseous manifestations divided into two cohorts – bone limited CRMO and complex CRMO. The two groups were compared in terms of demographic data, age at disease onset, number and site of bone lesions, laboratory biomarker values, and need of escalation to a second-line therapy. Results Thirty-seven children (30 female, 7 male) with confirmed CRMO were included in the analysis. The mean age at disease onset was 10 years. All but 3 patients presented with multifocal disease. Twenty-three children (62%) had at least one extraosseous manifestation (13 sacroiliitis, 8 inflammatory bowel disease, 6 skin disease [acne, pustulosis, or psoriasis], 7 arthritis). Complex CRMO was associated with a significantly higher ESR rate (p = 0.0064) and CRP level (p = 0.018). The groups did not differ in number of foci or in age at disease onset. Bone lesion distribution differed between the two groups with significantly more frequent involvement of clavicle (p = 0.011) and pelvis (p = 0.038) in patients with complex CRMO. Children with complex CRMO more often needed escalation of therapy to DMARDs and biologic agents. Conclusion Our data suggest that CRMO affecting solely the skeleton has milder course compared to complex CRMO with extraskeletal features. Further studies are needed to explore the clinical as well as the patient reported outcomes and promote individually tailored therapeutic strategies in both CRMO phenotypes