Content of bioactive constituents and antioxidant potential of Galium L. species

Qualitative phytochemical analyses of eight species from the genus Galium (G. corrudifolium, G. cruciata, G. divaricatum, G. lucidum, G. mollugo, G. palustre, G. parisiense, and G. verum), followed by spectrophotometric evaluation of their total phenolic, flavonoid and iridoid content, as well as antiradical capacity, were conducted. G. cruciata contained the greatest amount of total phenolics (111.00 mg gallic acid equivalents g–1 dry extract), while G. verum had the greatest amount of flavonoids (23.11 mg quercetin equivalents g–1 dry extract) and iridoids (461.30 mg aucubin equivalents g–1 dry extract). The best antioxidant (antiradical) activity was shown by G. cruciata (IC50 (ABTS) = 30.30 µg mL–1; IC50 (DPPH) = 27.62 µg mL–1), followed by G. divaricatum, G. verum and G. palustre. The same species were rich in various bioactive constituents and would be appropriate for inclusion in further investigations considering their biomedical potential. This work is licensed under a Creative Commons Attribution 4.0 International License

Tradicionalna upotreba, kemijski sastav i biološki učinci vrsta roda Galium L.

Species from the genus Galium L. (Rubiaceae) have a wide area of distribution and some of them are frequently used in folk medicine and human nutrition. Although today the application of these plant species in official medicine has not been recognized, recent findings indicate that their biomedical potential might be worth reconsidering. The paper gives a short overview of their traditional uses recorded in different countries together with their major bioactive compounds and the more recent results of various biological activity tests

Tradicionalna upotreba, kemijski sastav i biološki učinci vrsta roda Galium L.

Species from the genus Galium L. (Rubiaceae) have a wide area of distribution and some of them are frequently used in folk medicine and human nutrition. Although today the application of these plant species in official medicine has not been recognized, recent findings indicate that their biomedical potential might be worth reconsidering. The paper gives a short overview of their traditional uses recorded in different countries together with their major bioactive compounds and the more recent results of various biological activity tests