36 research outputs found
Cultural Heritage Digitization in Serbia: Standards, Policies, and Case Studies
The paper identifies necessary steps to create a national information system for management
and preservation of cultural heritage documentation. The Republic of Serbia, where the digitization
of cultural heritage is recognized as a segment of cultural development and officially accepted as
one of the methods for preservation and presentation of heritage documentation, is taken as a case
study. The paper describes the evolutionary path of the digitization process in Serbia and analyzes
the importance of the adoption of a legal framework and establishment of national standards in the
process of achieving the uniqueness in cultural heritage long-term sustainable documentation
management and preservation across cultural institutions
Alkylamino and aralkylamino derivatives of avarone and its mimetic as selective agents against non-small cell lung cancer cells, their antibacterial and antifungal potential
In this paper, the synthesis of fourteen alkylamino and arylamino derivatives of sesquiterpene quinone avarone and its model compound tert-butylquinone is described. Branched, cyclic, allylic and benzylic alkylamino/arylamino groups were introduced into the quinone moiety. For all the obtained derivatives, their biological activity and redox properties were studied. The cytotoxic activity of the synthesized derivatives towards multidrug resistant (MDR) human non-small cell lung carcinoma NCI-H460/R cells, their sensitive counterpart NCI-H460 and human normal keratinocytes (HaCaT) was investigated. The antimicrobial activity towards Gram-positive and Gram-negative bacteria, and fungal cultures was determined. Some of the synthesized derivatives showed selectivity for cancer cells, including MDR cells. Regarding their cell death induction potential, the most promising compounds were allylamino derivatives, preferentially triggering apoptosis, with high selectivity for cancer cells, including MDR cells. Several compounds showed promising antimicrobial activity, comparable to those of commercial antibiotic and antimycotic agents
Supplementary data for article: Aleksić, I.; Šegan, S.; Andrić, F.; Zlatović, M.; Moric, I.; Opsenica, D. M.; Senerovic, L. Long-Chain 4-Aminoquinolines as Quorum Sensing Inhibitors in Serratia Marcescens and Pseudomonas Aeruginosa. ACS Chemical Biology 2017, 12 (5), 1425–1434. https://doi.org/10.1021/acschembio.6b01149
Supporting information for: [https://doi.org/10.1021/acschembio.6b01149]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2461]Related to accepted version: [http://cherry.chem.bg.ac.rs/handle/123456789/3089
Supplementary material for the article: Jeremić, M.; Pešić, M.; Dinić, J.; Banković, J.; Novakovićc, I.; Šegan, D.; Sladić, D. Simple Avarone Mimetics as Selective Agents against Multidrug Resistant Cancer Cells. European Journal of Medicinal Chemistry 2016, 118, 107–120. https://doi.org/10.1016/j.ejmech.2016.04.011
Supplementary material for: [https://doi.org/10.1016/j.ejmech.2016.04.011]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2256
Supplementary data for article: N-benzyl derivatives of long-chained 4-Amino-7-chloro-quionolines as inhibitors of pyocyanin production in Pseudomonas aeruginosa
Supplementary data for article: N-benzyl derivatives of long-chained 4-Amino-7-chloro-quionolines as inhibitors of pyocyanin production in Pseudomonas aeruginosa
Supplementary data for article: Šegan, S. B.; Andrić, F.; Radoičić, A.; Opsenica, D. M.; Šolaja, B. A.; Zlatović, M.; Milojković-Opsenica, D. Correlation between Structure, Retention and Activity of Cholic Acid Derived Cis-Trans Isomeric Bis-Steroidal Tetraoxanes. Journal of Separation Science 2011, 34 (19), 2659–2667. https://doi.org/10.1002/jssc.201100185
Supporting information for: [https://doi.org/10.1002/jssc.201100185]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1212
Supplementary data for article: Šegan, S. B.; Trifković, J.; Verbić, T.; Opsenica, D. M.; Zlatović, M.; Burnett, J.; Šolaja, B. A.; Milojković-Opsenica, D. Correlation between Structure, Retention, Property, and Activity of Biologically Relevant 1,7-Bis(Aminoalkyl)Diazachrysene Derivatives. Journal of Pharmaceutical and Biomedical Analysis 2013, 72, 231–239. https://doi.org/10.1016/j.jpba.2012.08.025
Supplementary material for: [https://doi.org/10.1016/j.jpba.2012.08.025]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1555
Supplementary material for the article: Jeremić, M.; Pešić, M.; Dinić, J.; Banković, J.; Novakovićc, I.; Šegan, D.; Sladić, D. Simple Avarone Mimetics as Selective Agents against Multidrug Resistant Cancer Cells. European Journal of Medicinal Chemistry 2016, 118, 107–120. https://doi.org/10.1016/j.ejmech.2016.04.011
Supplementary material for: [https://doi.org/10.1016/j.ejmech.2016.04.011]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2256
Supplementary data for article: Aleksić, I.; Šegan, S.; Andrić, F.; Zlatović, M.; Moric, I.; Opsenica, D. M.; Senerovic, L. Long-Chain 4-Aminoquinolines as Quorum Sensing Inhibitors in Serratia Marcescens and Pseudomonas Aeruginosa. ACS Chemical Biology 2017, 12 (5), 1425–1434. https://doi.org/10.1021/acschembio.6b01149
Supporting information for: [https://doi.org/10.1021/acschembio.6b01149]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2461]Related to accepted version: [http://cherry.chem.bg.ac.rs/handle/123456789/3089