Normative Spectral Domain Optical Coherence Tomography Data in Healthy Turkish Children

<p><i>Purpose</i>: To determine the normative database of macular and retinal nerve fiber layer (RNFL) thickness parameters in healthy Turkish children by OCT. <i>Methods</i>: 318 eyes of 318 children (138 boys, 183 girls) aged between 3 and 17 years were evaluated. The children were scanned by Cirrus HD-OCT (Carl Zeiss Meditec) to measure the macula, RNFL, and optic nerve head parameters. <i>Results</i>: Axial length (AL) (<i>p</i> < 0.001, R²= 0.08), spherical equivalent (SE) (<i>p</i> < 0.001, R²= 0.12), and rim area (<i>p</i> < 0.001, R²= 0.15) were the strongest predictors of RNFL thickness. All of the macular measurements were significantly related to age (<i>p</i> < 0.001, R²> 5%). Average macular thickness (<i>p</i> < 0.01) and outer macula (<i>p</i> = 0.002) showed significant relationship with the AL and SE. <i>Conclusion</i>: This study ensures an age-adjusted pediatric normative database using OCT to diagnose and monitor macular diseases, optic nerve diseases, and glaucoma in children.</p