Evaluation of Sleep Related Breathing Disorders and Obstructive Sleep Apne Syndrome in Interstitial Lung Patients

Objective: Interstitial lung disease (ILD) may create sleep disturbances due to chronic disease-related stress, respiratory abnormalities and adverse effects of treatment. We aimed to determine the quality of sleep in ILD patients, and the incidence of Obstructive sleep apnea syndrome (OSAS) in these patients. Materials and Methods: Taken to this study were 52 patients who were followed up in our center due to ILD. Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI) were applied to the patients. Spirometry and diffusion test were performed. Polysomnography (PSG) was performed to 27 patients whose ESS were more than or equal to 10. Results: Demographic characteristics, body mass index, spirometry and diffusion measurements, PSQI global score and the sub-components of it didn’t show difference according to ESS daytime sleepiness. Sleep quality of 44% of the patients was determined to be poor by PSQI. PSQI global score and sub-components weren’t correlated with apnea-hypopnea index, stage 1 latency, sleep efficiency and nocturnal desaturation (p>0.05) in 27 patients who underwent PSG. We observed increased stage 1 sleep and decreased stage 2-3 and rapid eye movement sleep. As nocturnal hypoxemia was seen arousals (p=0.000, r=0.698) increased. OSAS was diagnosed in 19 (70%) of subjects. Conclusion: Although ILD patients don’t have daytime hypoxemia; they may have nocturnal hypoxemia and OSAS, which may effect their sleep quality. Therefore ILD patients should be evaluated for daytime sleepiness, and sleep-related breathing disorders

The relationship between smoking history, functional exercise capacity and airway obstruction severity in patients with chronic obstructive pulmonary disease

Aim and objective The aim of the study was to investigate the relationship between smoking history, functional exercise capacity and airway obstruction severity in patients with chronic obstructive pulmonary disease (COPD). Methods Thirty patients with stable COPD participated in this study. Demographic value and smoking history (pack-years) were recorded. Pulmonary function tests were performed. Functional exercise capacity was evaluated with six minute walking test (6MWT). The Pearson correlation coefficient was calculated to examine the correlation between the variables. Results The mean of age (years), smoking history (pack-years), forced expiratory volume in 1 second (FEV1 %), 6MWT distance (m) were 74.60, 47.30, 55.03, 382.70 respectively. The smoking history had significant negative correlation with FEV1 % (r=-0.374, p=0.042) and 6MWT distance (r=-0.426, p=0.019). Conclusions The study showed that smoking history had significant negative correlation with functional exercise capacity and airway obstruction severity in patients with COPD. By reducing cigarette consumption, functional exercise capacity can be increased and the severity of airway obstruction can be decreased