Sexual dysfunction is related with childhood trauma in female patients with fibromyalgia

Giriş: Çocukluk çağı travması (ÇÇT) fibromiyalji sendromunda (FMS) sık görülmektedir ve çeşitli fiziksel ve ruhsal sorunlara neden olabilmektedir. ÇÇTli bireylerde cinsel işlevler ciddi biçimde etkilenebilmektedir. Bu çalışmada FMSli kadın hastalarda ÇÇTnin cinsel işlevlerle ilişkisinin incelenmesi hedeflenmiştir. Yöntem: Çalışmaya ardışık olarak başvuran ayaktan FMSli kadın hastalar (s=49, ortalama yaş: 40.82±6.91) ve yaş ve eğitim durumu açısından benzer olan kontrol grubu (s=45, ortalama yaş: 38.60±5.84) alındı. Fibromiyalji Etki Anketi (FEA), Çocuk- luk Çağı Ruhsal Travmaları Ölçeği (CTQ-28), Kadın Cinsel İşlev İndeksi (KCİİ), Beck Depresyon Ölçeği (BDÖ), Durumluk-Sürekli Kaygı Envanteri (DSKE) ve Görsel-Analog Skalası (GAS) değerlendirme aracı olarak kullanıldı. Bulgular: Hastaların sağlıklı kontrollere göre FSFI puanları anlamlı biçimde daha düşüktü. CTQ-28in toplam, emosyonel istismar, fiziksel istismar, emosyonel ihmal, fiziksel ihmal alt ölçeklerinde hastaların puanları sağlıklı kontrollere göre anlamlı biçimde daha yüksekti. Hasta grubunda FSFI toplam puanı ile CTQ-28 puanı arasında anlamlı derecede negatif bağıntı saptandı. Çoklu hiyerarşik lineer regresyon analizlerinde hasta grubunda CİBin belirleyicileri FMSnin ağırlık derecesi ve ÇÇTydi. Kontrol grubunda ise regresyon denklemi anlamlı sonuç verme- di. Tartışma: Çocukluk döneminde fiziksel ve emosyonel istismar öyküsü FMS grubunda daha sıktı ve cinsel işlev bozukluğu ile ilişkili bulundu. Erken yaşta travma, stres işlemeyi ve günlük stresle başa çıkmayı etkileyebilir. Sonuçta kişilerarası ilişkilerde aşırı duyarlılığa, cinsel eşle yakınlık kurma zorluğuna ve dolayısıyla cinselişlev bozukluklarına neden olabilir. işlev işlevObjective: Childhood trauma (CT) is frequently observed in fibromyalgia syndrome (FMS) and may cause various physical and mental morbidities. Sexual functioning is severely affected by CT. It was aimed to assess of the relationship between CT and sexual functioning in female patients with FMS. Methods: Consecutive outpatients with FMS (n=49, mean age: 40.82±6.91) and a control group similar to patient group in terms of age and education (n=45, mean age: 38.60±5.84) were enrolled. Fibromyalgia Impact Questionnaire (FIQ), Female Sexual Functioning Index (FSFI), Childhood Trauma Questionnaire (CTQ-28), Beck Depression Inventory (BDI), State- Trait Anxiety Inventory (STAI) and Visual Analog Scale (VAS) were the measures. Results: Patients had signify- cantly lower scores than healthy control group in FSFI. Total, emotional abuse, physical abuse, emotional neglect and physical neglect subscores of CT scale was significantly higher in FMS group. FSFI total score and CTQ-28 score was negatively correlated significantly in patient group. Predictors of sexual dysfunction in FMS was impact of the disease and CT in linear multiple hierarchical regression analyses. Regression equation was not significant in control group. Discussion: History of physical and emotional abuse at childhood was more frequent in this FMS sample and was related with sexual dysfunction. Trauma at early age may disturb stress processing and coping with daily stress. That may cause fragility in interpersonal relationships, difficulty in feeling warm towards the partner and consequently sexual dysfunctions

The Effects of Bone Mineral Density and Level of Serum Vitamin-D on Pain and Quality of Life in Fibromialgia Patients - Original Investigation

Aim: The purpose of this study is to determine bone mineral density (BMD) and the levels of serum 25-OH-vitamin D3 in premenopausal Fibromyalgia Syndrome (FMS) patients, and to examine the effect of them to the pain and quality of life in premenopausal FMS patients. Material and Methods: Premenouposal 30 patients with fibromyalgia and 30 healthy controls included the study. The demographic characteristic, serum values, vitamin D levels, bone mineral density measurements, Visual Analog Scala (VAS), Beck Depression Inventory (BDI), Short Form- 36 (SF-36) and Fibromyalgia Impact Questionery Form (FIQ) were determined. Patient and control group were compared in terms of these parameters. Results: There was no significant difference of Vitamin D levels and bone mineral density between case and controls. There was no significant difference between the groups with low and high vitamin D levels in terms of VAS, FIQ, BDI in SF-36 in FMS patients. There was no significant change with regard to VAS, FIQ, BDI, and SF36 between FMS patients with high or low BMD. Conclusion: There is no difference of vitamin D levels and bone mineral density between FMS patients and control group, vitamin D levels and bone mineral density have no effect on pain and quality of life in premenopausal patients with FMS. (From the World of Osteoporosis 2010;16:53-7