ESTRO-ACROP guideline on surface guided radiation therapy

Surface guidance systems enable patient positioning and motion monitoring without using ionising radiation. Surface Guided Radiation Therapy (SGRT) has therefore been widely adopted in radiation therapy in recent years, but guidelines on workflows and specific quality assurance (QA) are lacking. This ESTRO-ACROP guideline aims to give recommendations concerning SGRT roles and responsibilities and highlights common challenges and potential errors. Comprehensive guidelines for procurement, acceptance, commissioning, and QA of SGRT systems installed on computed tomography (CT) simulators, C-arm linacs, closed-bore linacs, and particle therapy treatment systems are presented that will help move to a consensus among SGRT users and facilitate a safe and efficient implementation and clinical application of SGRT. Keywords: ACROP; ESTRO; Guideline; SGRT; Surface guided radiation therapy

Do I-Pass for FAIR?:A self-assessment tool to measure the FAIR-ness of an organization

The 15 FAIR data principles are intended to be applied to a dataset, but the acronym FAIR is also used as an adjective for other (digital) matters, such as FAIR data stewardship, FAIR data infrastructure and FAIR data services. Moreover, in the context of Open Science and scientific integrity, more and more Dutch universities and research organizations discuss a FAIR organization as an important goal, thus implementing RDM practices and support with the FAIR principles as a main driver. Triggered by this use of the acronym FAIR for organizations, an LCRDM (National Coordination Point Research Data Management) task group explored the definition, characteristics and principles of a so-called ‘FAIR enabling organization’. The task group delivered two products: (1) a definition for a FAIR enabling organization and (2) a self-assessment tool to evaluate the FAIR-ness of a research organization (research institute, university or university of applied sciences). This self-assessment tool is a simple instrument, presented in an editable PDF form. By answering the questions and evaluating the level (beginner, intermediate, or advanced) at which you assess the performance of your organization, you will be able to define the actual FAIR-ness. In addition you can define a Road Map to become a FAIR Enabling Research Organization using the information in de more advances level(s)

PET imaging of hypoxia using [F-18]HX4: a phase I trial

 Download the images using these instructions and this DOI : 10.1007/s00259-010-1437-x Background and purposeNon-invasive PET imaging of tumour hypoxia could help in the selection of those patients who could benefit from chemotherapy or radiation with specific antihypoxic treatments such as bioreductive drugs or hypoxic radiosensitizers. In this phase I trial, we aimed to determine the toxicity of [18F]HX4, a member of the 2-nitroimidazole family, at different dose levels. The secondary aim was to analyse image quality related to the HX4 dose and the timing of imaging.MethodsPatients with a..