Secondary metabolites of hypericum species from the drosanthe and olympia sections

, fatihyayla/0000-0002-6490-6288; Jakstas, Valdas/0000-0001-7627-6263WOS: 000375936200012Eight Hypericum species native to Southern Turkey from Drosanthe and Olympia sections were investigated for the presence of several bioactive compounds, namely, hypericin, pseudohypericin, hyperforin, adhyperforin, the chlorogenic, neochlorogenic, caffeic and 2,4-dihydroxybenzoic acids, hyperoside, isoquercitrin, quercitrin, quercetin, avicularin, rutin, (+)-catechin, (-)-epicatechin, mangiferin, I3, II8-biapigenin, and amentoflavone for the first time. Plants were harvested at flowering, dried at room temperature, dissected into different tissues, and assayed for chemical contents. HPLC analysis of methanolic fractions displayed similar chemical profile and significant quantitative differences among the investigated taxa. the present results support the taxonomic value of hypericins, rutin, and mangiferin at the sectional level and make an important contribution to our current knowledge about Hypericum chemistry. Such kind of data could also be beneficial for explanation of the chemo-taxonomic utility of the corresponding compounds as well as phytochemical evaluation of the species tested. (C) 2016 SAAB. Published by Elsevier B.V. All rights reserved

Physiological and physical seed dormancy of some hypericum species growing in Turkey.

To investigate the nature of dormancy in Hypericum androsaemum, H. scabrum, H. lydum and H. tetrapterum seeds which did not show germination under nor mal laboratory conditions. The 15 day long germination experiment under the constant light pre ceded by 30 min soaking in water (tap water, 40, 50 and 60°C hot water), GA3 (50, 100 and 150 ppm) and H2SO4 (1, 2 and 3%) was per formed. The germination response to the pre-soaking treatments was variable and discussed as a possible result of double dormancy involving partially dormant embryo and a chemical inhibitor for H. androsaemum and H. scabrum. Seed germination was restricted only by hard seed coat in H. lydum, and H. tetrapterum indicating the presence of physical dormancy.  

Hypericum origanifolium Willd.: the essential oil composition of a new valuable species

Bertoli, Alessandra/0000-0002-0701-5163WOS: 000366065200080Turkish Hypericum origanifolium Willd has been recently considered for its hypericin and phenolic content as a potential substitute of the well-established EU market position Hypericum perforatum. However, a complete phytochemical characterization of H. origamfolium has not carried out yet in order to assert its potential industrial value.The present paper represents the first attempt to define the aromatic fingerprint of a representative wild Turkish H. origanifolium Willd. population. in addition, its volatiles were studied as potential discriminating constituents between H. perforatum and H. origanifolium with a similar hypericin and phenolic composition. (C) 2015 Published by Elsevier B.V

Volatile secondary metabolites of Hypericum tetrapterum and Hypericum bithynicum

The phytochemical analyses on the flowering aerial parts resulted in identification of 32 and 30 compounds which represent 100% of total volatile components in Hypericum tetrapterum and Hypericum bithynicum (Hypericaceae), respectively. Among the chemicals, methylpalmitate, p-menthone, linalool and α-santalene for H. tetrapterum and camphor, α-bisabolol, methylpalmitate and nerolidol for H. bithynicum were recognized as major volatile ingredients. Volatile profile of H. tetrapterum from Turkish origin had never been described and this is the first report on volatile chemistry of H. bithynicum. Chemotaxonomic significance of the tested compounds was also discussed

Distribution of phenolic compounds and antioxidant activity in plant parts and populations of seven underutilized wild achillea species

Evaluation of phytochemical composition of underutilized Achillea species provides the primary selection of germplasms with the desired quality of raw material for their further applications. The aim of the study was to evaluate the comprehensive distribution patterns of phenolic compounds in seven wild Achillea spp. and their plant parts, and to assess their antioxidant activity. Plant material was collected from different sites in Turkey. A complex of hydroxycinnamic acids, flavonols and flavones was identified and quantified in methanolic extracts using HPLC-PDA method. Antioxidant activity was assessed by radical scavenging assay. The results showed that qualitative and qualitative profiles of caffeoylquinic acids and flavonoids were species-specific, explaining the characteristic patterns of their variation in the corresponding species and plant parts. The highest total amount of caffeoylquinic acids was detected in A. setacea. A. arabica exposed the highest accumulation of mono-caffeoylquinic acids and flavonoids with the greatest levels of quercetin and luteolin derivatives and the flavonol santin. Santin was detected in all plant parts of A. cappadocica, A. setacea, A. santolinoides subsp. wilhelmsii, and A. arabica. A notable antiradical capacity was confirmed in A. arabica, A. setacea and A. cappadocica plant extracts. The leaves of all studied species were found to have priority over inflorescences and stems in terms of radical scavenging activity. The new data complemented the information that may be relevant for the continuation of chemophenetic studies in the heterogeneous genus Achillea

Phenolic compounds and antioxidant activity of Achillea arabica populations

In this study, we aimed to present the screening of the contents of phenolics including caffeoylquinic acid derivatives, quercetin, luteolin, apigenin and some their derivatives as well as santin and total antioxidant activity for a total of 53 populations of Achillea arabica Kotschy from different parts of Turkey. The flowering plant material was evaluated for phenolic compound contents by using High Performance Liquid Chromatog-raphy (HPLC-PDA) fingerprint analysis. The antioxidant activity of plant extracts was evaluated by free radi-cal scavenging (ABTS) and ferric reducing antioxidant power (FRAP) assays. Phenolic contents and antioxidant activity varied remarkably across populations and a significant correlation was found between particular phenolics content and antioxidant activity, suggesting that phenolic metabolites can be regarded as main contributors to the observed antioxidant capacity. The data are valuable in selecting of germplasms, whose plant material may be important in the development of new bioproducts and present A. arabica as a convenient and readily accessible source of natural antioxidants that can be incorporated in food and phar-maceutical applications. (C) 2022 SAAB. Published by Elsevier B.V. All rights reserved

Trends in Phenolic Profiles of <i>Achillea millefolium</i> from Different Geographical Gradients

The traditional widely used raw material of Achillea millefolium is currently mainly derived from wild populations, leading to diversification and uncertainty in its quality. The aim of the study was to determine the accumulation differences of phenolic compounds between geographically distant populations of Achillea millefolium from northern and southern gradients. Plant material was collected from Gaziantep and Nevşehir provinces in Turkey and from wild populations in Lithuania. A complex of nine hydroxycinnamic acids and eleven flavonoids was identified and quantified in the methanolic extracts of inflorescences, leaves, and stems using the HPLC-PDA method. Caffeoylquinic acids predominated in leaves, while inflorescences tended to prevail in flavonoids. The PCA score plot model represented the quantitative distribution pattern of phenolic compounds along a geographical gradient of populations. The content of phenolic compounds in plant materials from northern latitudes was more than twice that of plants from southern latitudes. A significant correlation of individual phenolic compounds with latitude/longitude corresponded to their differences between two countries. Differences in accumulation of caffeoylquinic acids and flavonoids revealed several intraspecific groups within A. millefolium. Our findings suggest that spatial geographical data on the distribution of phenolic compounds in A. millefolium populations could be used as a tool to find potential collection sites for high-quality raw materials